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Revolution Medicines, Inc.

RVMD
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001628171

In the last 90 days, Revolution Medicines, Inc. insiders filed 0 open-market purchases and 17 sales; 693 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; Duquesne Family Office is the only superinvestor holding it.

Other share classesRVMDW

13F holders, Q4 2025

Institutional positions in Revolution Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+69 vs. Q3 2025
Shares held
199.3M
+7.61M (+4.0%) vs. Q3 2025
Total value
$15.9B
+$6.92B (+77.3%) vs. Q3 2025
New holders
107
136 more added
Sold out
38
101 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RVMD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 128 institutionsQ2 2021: 130 institutionsQ3 2021: 114 institutionsQ4 2021: 117 institutionsQ1 2022: 126 institutionsQ2 2022: 135 institutionsQ3 2022: 142 institutionsQ4 2022: 135 institutionsQ1 2023: 152 institutionsQ2 2023: 139 institutionsQ3 2023: 168 institutionsQ4 2023: 184 institutionsQ1 2024: 210 institutionsQ2 2024: 223 institutionsQ3 2024: 255 institutionsQ4 2024: 281 institutionsQ1 2025: 284 institutionsQ2 2025: 308 institutionsQ3 2025: 323 institutionsQ4 2025: 387 institutionsQ1 2026: 514 institutionsQ2 2026: 693 institutions
Value heldQ4 2025: $15.9B
Q1 2021: $3.05BQ2 2021: $2.23BQ3 2021: $1.99BQ4 2021: $1.85BQ1 2022: $1.89BQ2 2022: $1.49BQ3 2022: $1.74BQ4 2022: $2.10BQ1 2023: $2.34BQ2 2023: $2.99BQ3 2023: $3.11BQ4 2023: $4.59BQ1 2024: $5.18BQ2 2024: $6.54BQ3 2024: $7.74BQ4 2024: $8.45BQ1 2025: $6.83BQ2 2025: $7.02BQ3 2025: $8.96BQ4 2025: $15.9BQ1 2026: $19.1BQ2 2026: $40.1B
Institutions holding RVMD and their total value by quarter
QuarterHoldersValue
Q2 2026693$40.1B
Q1 2026514$19.1B
Q4 2025387$15.9B
Q3 2025323$8.96B
Q2 2025308$7.02B
Q1 2025284$6.83B
Q4 2024281$8.45B
Q3 2024255$7.74B
Q2 2024223$6.54B
Q1 2024210$5.18B
Q4 2023184$4.59B
Q3 2023168$3.11B
Q2 2023139$2.99B
Q1 2023152$2.34B
Q4 2022135$2.10B
Q3 2022142$1.74B
Q2 2022135$1.49B
Q1 2022126$1.89B
Q4 2021117$1.85B
Q3 2021114$1.99B
Q2 2021130$2.23B
Q1 2021128$3.05B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Revolution Medicines, Inc.; share changes are against Q3 2025.

Institutions holding RVMD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Fisher Asset Management, LLC241,057$19.2M0.01%+233,752+3,199.9%Added
Raymond James Financial Inc244,174$19.4M0.01%−33,986−12.2%Reduced
Swiss National Bank276,331$22.0M0.01%+5,500+2.0%Added
Two Sigma Advisers, LP287,646$22.9M0.04%+248,655+637.7%Added
California Public Employees Retirement System291,006$23.2M0.01%+60,032+26.0%Added
Vestal Point Capital, LP295,000$23.5M0.86%−335,000−53.2%Reduced
Jennison Associates LLC305,260$24.3M0.01%+305,260New
Nicholas Investment Partners, LP317,711$25.3M1.84%+49,800+18.6%Added
Voloridge Investment Management, LLC322,289$25.7M0.09%+173,144+116.1%Added
Boothbay Fund Management, LLC327,152$26.1M0.68%+62,144+23.4%Added
Mass General Brigham, Inc344,091$27.4M3.38%+344,091New
UBS Asset Management Americas Inc349,412$27.8M0.01%+8,045+2.4%Added
Defilade Capital Management, L.P.363,454$28.9M3.92%+363,454New
Invesco Ltd.367,851$29.3M0.00%+166,909+83.1%Added
Checkpoint Capital L.P.370,000$29.5M9.34%−122,300−24.8%Reduced
TD Asset Management Inc370,520$29.5M0.02%−165,084−30.8%Reduced
Eventide Asset Management, LLC378,261$30.1M0.47%−216,777−36.4%Reduced
Marshall Wace, LLP386,191$30.8M0.03%+225,095+139.7%Added
Lord, Abbett & Co. LLC399,484$31.8M0.10%+399,484New
Boxer Capital Management, LLC400,000$31.9M6.97%00.0%Unchanged
Nuveen, LLC406,241$32.4M0.01%+68,767+20.4%Added
Balyasny Asset Management LLC415,207$33.1M0.06%+319,611+334.3%Added
JPMorgan Chase & Co421,627$33.6M0.00%−2,076,700−83.1%Reduced
Two Sigma Investments, LP421,735$33.6M0.05%+412,628+4,530.9%Added
Frontier Capital Management Co LLC430,768$34.3M0.36%+307,988+250.8%Added
TCG Crossover Management, LLC436,473$34.8M1.15%00.0%Unchanged
Point72 Asset Management, L.P.446,616$35.6M0.06%+446,616New
American Century Companies Inc467,360$37.2M0.02%+16,346+3.6%Added
Royal Bank of Canada503,721$40.1M0.01%+311,392+161.9%Added
MPM Oncology Impact Management LP505,672$40.3M4.61%+189,950+60.2%Added
MIC Capital Management UK LLP508,569$40.5M9.18%00.0%Unchanged
Bank of New York Mellon Corp542,069$43.2M0.01%+12,799+2.4%Added
DAFNA Capital Management LLC604,514$48.1M11.18%−52,662−8.0%Reduced
BNP Paribas Arbitrage, SA619,387$49.3M0.03%+194,706+45.8%Added
First Turn Management, LLC638,385$50.8M5.81%−4,665−0.7%Reduced
Morgan Stanley651,732$51.9M0.00%−782,910−54.6%Reduced
Frazier Life Sciences Management, L.P.797,455$63.5M1.71%−200,000−20.1%Reduced
Millennium Management LLC800,118$63.7M0.05%+371,809+86.8%Added
Northern Trust Corp850,323$67.7M0.01%−9,225−1.1%Reduced
Bank of America Corp879,845$70.1M0.01%+125,978+16.7%Added
AIHC Capital Management Ltd900,392$71.7M67.21%+900,392New
AH Capital Management, L.L.C.921,099$73.4M4.64%−1,827,424−66.5%Reduced
Hood River Capital Management LLC945,585$75.3M0.83%+17,462+1.9%Added
Candriam Luxembourg S.C.A.1,030,992$82.1M0.41%+162,268+18.7%Added
Franklin Resources Inc1,060,171$84.4M0.02%+108,681+11.4%Added
Jane Street Group, LLC1,090,416$86.9M0.10%+492,961+82.5%Added
Pictet Asset Management Holding SA1,137,121$90.7M0.09%−174,620−13.3%Reduced
Jefferies Financial Group Inc.1,141,195$90.9M0.74%+1,128,195+8,678.4%Added
Dimensional Fund Advisors LP1,161,646$92.5M0.02%−279,172−19.4%Reduced
Integral Health Asset Management, LLC1,200,000$95.6M4.84%+800,000+200.0%Added
Caligan Partners LP1,283,900$102.3M9.36%+219,651+20.6%Added
Citadel Advisors LLC1,302,361$103.7M0.07%+122,276+10.4%Added
Siren, L.L.C.1,335,075$106.3M3.17%+291,355+27.9%Added
Rock Springs Capital Management LP1,335,270$106.4M5.46%00.0%Unchanged
D. E. Shaw & Co., Inc.1,613,730$128.5M0.10%+801,451+98.7%Added
Charles Schwab Investment Management Inc1,683,729$134.1M0.02%+48,334+3.0%Added
Holocene Advisors, LP1,907,948$152.0M0.32%−1,529,335−44.5%Reduced
Logos Global Management LP2,000,000$159.3M10.62%+250,000+14.3%Added
Polar Capital Holdings Plc2,013,791$160.4M0.73%+1,535,686+321.2%Added
Ameriprise Financial Inc2,056,857$163.8M0.04%+832,098+67.9%Added
Avoro Capital Advisors LLC2,170,000$172.8M1.70%+2,170,000New
Lunate Capital Ltd2,196,200$174.9M66.20%00.0%Unchanged
T. Rowe Price Investment Management, Inc.2,200,376$175.3M0.11%−2,581,942−54.0%Reduced
Adage Capital Partners GP, L.L.C.2,205,555$175.7M0.27%+1,463,155+197.1%Added
Norges Bank2,455,347$195.6M0.02%+2,455,347New
Goldman Sachs Group Inc2,491,583$198.5M0.03%+1,753,557+237.6%Added
Woodline Partners LP2,500,895$199.2M0.77%−414,988−14.2%Reduced
Casdin Capital, LLC2,577,333$205.3M12.75%−70,000−2.6%Reduced
General Atlantic LLC2,812,928$224.0M7.80%+338,500+13.7%Added
Westfield Capital Management Co LP2,845,013$226.6M0.94%+331,046+13.2%Added
Deerfield Management Company, L.P. (Series C)2,894,613$230.6M2.96%−755,729−20.7%Reduced
UBS Group AG3,087,937$246.0M0.05%+1,998,972+183.6%Added
Geode Capital Management, LLC3,161,963$251.9M0.02%+16,323+0.5%Added
Alphabet Inc.3,345,102$266.4M10.33%−788,175−19.1%Reduced
BVF Inc3,356,782$267.4M9.00%−618,131−15.6%Reduced
Price T Rowe Associates Inc3,404,717$271.2M0.03%−468,989−12.1%Reduced
State Street Corp4,109,290$327.3M0.01%−1,145,349−21.8%Reduced
Bellevue Group AG5,005,719$398.7M7.56%−568,119−10.2%Reduced
Paradigm Biocapital Advisors LP6,644,403$529.2M14.17%+421,112+6.8%Added
Wellington Management Group LLP6,987,639$556.6M0.10%−2,825,797−28.8%Reduced
Nextech Invest, Ltd.7,601,087$605.4M58.53%00.0%Unchanged
FMR LLC8,587,981$684.0M0.03%−813,706−8.7%Reduced
BlackRock, Inc.8,926,656$711.0M0.01%+598,898+7.2%Added
Baker Bros. Advisors LP9,455,357$753.1M4.41%00.0%Unchanged
Janus Henderson Group PLC12,303,502$980.0M0.44%+947,448+8.3%Added
Farallon Capital Management, L.L.C.14,582,796$1.16B6.04%−42,896−0.3%Reduced
Vanguard Group Inc16,719,886$1.33B0.02%+1,056,792+6.7%Added
Caption Management, LLC0$00.00%−314,836−100.0%Sold out
Renaissance Technologies LLC0$00.00%−253,104−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−191,327−100.0%Sold out
Caisse de Depot Et Placement du Quebec0$00.00%−108,400−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−55,323−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−34,575−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−31,591−100.0%Sold out
Clear Harbor Asset Management, LLC0$00.00%−22,110−100.0%Sold out
Jump Financial, LLC0$00.00%−21,495−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−20,000−100.0%Sold out
Quadrature Capital Ltd0$00.00%−17,874−100.0%Sold out
Sig Brokerage, LP0$00.00%−10,411−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−10,080−100.0%Sold out