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Revolution Medicines, Inc.

RVMD
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001628171

In the last 90 days, Revolution Medicines, Inc. insiders filed 0 open-market purchases and 17 sales; 693 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; Duquesne Family Office is the only superinvestor holding it.

Other share classesRVMDW

13F holders, Q4 2025

Institutional positions in Revolution Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+69 vs. Q3 2025
Shares held
199.3M
+7.61M (+4.0%) vs. Q3 2025
Total value
$15.9B
+$6.92B (+77.3%) vs. Q3 2025
New holders
107
136 more added
Sold out
38
101 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RVMD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 128 institutionsQ2 2021: 130 institutionsQ3 2021: 114 institutionsQ4 2021: 117 institutionsQ1 2022: 126 institutionsQ2 2022: 135 institutionsQ3 2022: 142 institutionsQ4 2022: 135 institutionsQ1 2023: 152 institutionsQ2 2023: 139 institutionsQ3 2023: 168 institutionsQ4 2023: 184 institutionsQ1 2024: 210 institutionsQ2 2024: 223 institutionsQ3 2024: 255 institutionsQ4 2024: 281 institutionsQ1 2025: 284 institutionsQ2 2025: 308 institutionsQ3 2025: 323 institutionsQ4 2025: 387 institutionsQ1 2026: 514 institutionsQ2 2026: 693 institutions
Value heldQ4 2025: $15.9B
Q1 2021: $3.05BQ2 2021: $2.23BQ3 2021: $1.99BQ4 2021: $1.85BQ1 2022: $1.89BQ2 2022: $1.49BQ3 2022: $1.74BQ4 2022: $2.10BQ1 2023: $2.34BQ2 2023: $2.99BQ3 2023: $3.11BQ4 2023: $4.59BQ1 2024: $5.18BQ2 2024: $6.54BQ3 2024: $7.74BQ4 2024: $8.45BQ1 2025: $6.83BQ2 2025: $7.02BQ3 2025: $8.96BQ4 2025: $15.9BQ1 2026: $19.1BQ2 2026: $40.1B
Institutions holding RVMD and their total value by quarter
QuarterHoldersValue
Q2 2026693$40.1B
Q1 2026514$19.1B
Q4 2025387$15.9B
Q3 2025323$8.96B
Q2 2025308$7.02B
Q1 2025284$6.83B
Q4 2024281$8.45B
Q3 2024255$7.74B
Q2 2024223$6.54B
Q1 2024210$5.18B
Q4 2023184$4.59B
Q3 2023168$3.11B
Q2 2023139$2.99B
Q1 2023152$2.34B
Q4 2022135$2.10B
Q3 2022142$1.74B
Q2 2022135$1.49B
Q1 2022126$1.89B
Q4 2021117$1.85B
Q3 2021114$1.99B
Q2 2021130$2.23B
Q1 2021128$3.05B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Revolution Medicines, Inc.; share changes are against Q3 2025.

Institutions holding RVMD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Mirae Asset Global Investments Co., Ltd.21,289$1.70M0.00%+14,062+194.6%Added
DekaBank Deutsche Girozentrale50,000$1.72M0.00%00.0%Unchanged
Shay Capital LLC22,260$1.77M0.29%−23,740−51.6%Reduced
Fiduciary Trust Co23,098$1.84M0.02%+30.0%Added
Comerica Bank23,285$1.85M0.01%−466,931−95.3%Reduced
Dark Forest Capital Management LP23,458$1.87M0.09%+23,458New
Squarepoint Ops LLC23,635$1.88M0.00%+13,256+127.7%Added
OrbiMed Advisors LLC25,900$2.06M0.04%+25,900New
Profund Advisors LLC26,929$2.14M0.07%−10,150−27.4%Reduced
Sandy Cove Advisors, LLC27,008$2.15M0.64%00.0%Unchanged
Headlands Technologies LLC27,275$2.17M0.18%−9,925−26.7%Reduced
KVP Capital Advisors, LP27,500$2.19M2.26%+27,500New
Raiffeisen Bank International AG29,000$2.31M0.03%+9,000+45.0%Added
Guggenheim Capital LLC29,982$2.39M0.02%−391−1.3%Reduced
KLP Kapitalforvaltning AS30,004$2.39M0.01%+1,100+3.8%Added
Weiss Asset Management LP30,022$2.39M0.03%+30,022New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.31,514$2.49M0.00%00.0%Unchanged
Quantinno Capital Management LP32,063$2.55M0.01%+7,348+29.7%Added
Deutsche Bank AG32,217$2.57M0.00%+130+0.4%Added
Trexquant Investment LP32,463$2.59M0.02%−131,250−80.2%Reduced
Brevan Howard Capital Management LP32,807$2.61M0.05%+1,644+5.3%Added
Aquatic Capital Management LLC33,537$2.67M0.08%−13,028−28.0%Reduced
China Universal Asset Management Co., Ltd.34,001$2.71M0.21%−8,766−20.5%Reduced
S&CO Inc34,171$2.72M0.17%+12,000+54.1%Added
Diadema Partners LP37,020$2.95M1.76%−22,059−37.3%Reduced
Arizona State Retirement System39,161$3.12M0.02%−2,138−5.2%Reduced
First Trust Advisors LP39,365$3.14M0.00%+39,365New
Erste Asset Management GmbH39,400$3.17M0.03%00.0%Unchanged
Group One Trading, L.P.40,145$3.20M0.09%+35,865+838.0%Added
Cinctive Capital Management LP42,635$3.40M0.20%+42,635New
Creative Planning44,144$3.52M0.00%+5,206+13.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)45,517$3.63M0.01%+3,716+8.9%Added
Citigroup Inc45,702$3.64M0.00%+28,402+164.2%Added
Ieq Capital, LLC47,412$3.78M0.01%+41,912+762.0%Added
Legato Capital Management LLC48,751$3.88M0.33%+14,097+40.7%Added
State of New Jersey Common Pension Fund D50,085$3.99M0.01%−8,223−14.1%Reduced
Wedmont Private Capital40,056$4.11M0.14%+50+0.1%Added
Public Employees Retirement System of Ohio52,165$4.15M0.01%−1,978−3.7%Reduced
Sphera Funds Management Ltd.52,500$4.18M0.87%−7,500−12.5%Reduced
Handelsbanken Fonder AB54,175$4.32M0.01%−4,200−7.2%Reduced
Superstring Capital Management LP54,879$4.37M2.34%+54,879New
Moore Capital Management, LP55,600$4.43M0.09%00.0%Unchanged
Voya Investment Management LLC60,237$4.80M0.00%+12,703+26.7%Added
StemPoint Capital LP62,032$4.94M0.85%−123,348−66.5%Reduced
SEI Investments Co62,489$4.98M0.00%+10,559+20.3%Added
General American Investors Co Inc64,045$5.10M0.32%+64,045New
EAM Investors, LLC64,236$5.12M0.57%+64,236New
Universal- Beteiligungs- und Servicegesellschaft mbH65,627$5.23M0.01%−13,105−16.6%Reduced
Seven Fleet Capital Management LP65,800$5.24M3.55%+65,800New
Alliancebernstein L.P.66,523$5.30M0.00%+4,392+7.1%Added
Allianz Asset Management GmbH71,570$5.70M0.01%−1,907−2.6%Reduced
Treasurer of the State of North Carolina72,617$5.78M0.02%−5,301−6.8%Reduced
Police & Firemen's Retirement System of New Jersey73,197$5.83M0.05%−3,732−4.9%Reduced
Rafferty Asset Management, LLC74,698$5.95M0.02%−105,135−58.5%Reduced
M&G Plc88,952$7.12M0.04%+88,952New
HealthInvest Partners AB90,184$7.18M2.29%+4,829+5.7%Added
Tudor Investment Corp Et Al92,391$7.36M0.04%+92,391New
Worldquant Millennium Advisors LLC94,010$7.49M0.03%+84,019+840.9%Added
Man Group plc97,505$7.77M0.01%+91,511+1,526.7%Added
State of Wisconsin Investment Board97,804$7.79M0.02%−12,793−11.6%Reduced
Russell Investments Group, Ltd.98,880$7.88M0.01%−25,759−20.7%Reduced
Granahan Investment Management Inc99,194$7.90M0.34%−19,498−16.4%Reduced
Opaleye Management Inc.100,000$7.96M1.05%00.0%Unchanged
Affinity Asset Advisors, LLC100,000$7.96M0.57%00.0%Unchanged
Tema ETFs LLC100,603$8.01M0.62%−26,318−20.7%Reduced
NEOS Investment Management LLC101,888$8.12M0.05%−25,033−19.7%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.103,552$8.25M0.01%+102,276+8,015.4%Added
Artia Global Partners LP104,190$8.30M1.33%00.0%Unchanged
Zweig-DiMenna Associates LLC104,600$8.33M0.59%+104,600New
Canada Pension Plan Investment Board108,675$8.66M0.01%+108,675New
Standard Life Aberdeen plc113,268$9.02M0.01%+113,268New
Gotham Asset Management, LLC113,829$9.07M0.03%+14,715+14.8%Added
Algert Global LLC113,930$9.07M0.14%−52,385−31.5%Reduced
Eagle Health Investments LP115,900$9.23M2.03%+115,900New
WCM Investment Management, LLC117,215$9.34M0.02%−136,162−53.7%Reduced
Bessemer Group Inc117,662$9.37M0.01%−126,205−51.8%Reduced
HighVista Strategies LLC120,240$9.58M2.47%−55,208−31.5%Reduced
MUFG Securities EMEA plc123,000$9.80M0.11%+123,000New
Bank of Nova Scotia125,913$10.0M0.01%+125,913New
AQR Capital Management LLC127,170$10.1M0.01%+56,881+80.9%Added
New York State Common Retirement Fund129,407$10.3M0.01%+9,600+8.0%Added
State Board of Administration of Florida Retirement System130,936$10.4M0.02%+45,360+53.0%Added
California State Teachers Retirement System135,390$10.8M0.01%−4,695−3.4%Reduced
Barclays PLC136,048$10.8M0.00%−154,401−53.2%Reduced
Ikarian Capital, LLC138,142$11.0M1.42%+138,142New
Victory Capital Management Inc139,312$11.1M0.01%−112,498−44.7%Reduced
ADAR1 Capital Management, LLC145,079$11.6M0.86%+5,943+4.3%Added
PFM Health Sciences, LP151,453$12.1M1.22%−179,616−54.3%Reduced
Legal & General Group Plc153,380$12.2M0.00%−2,009−1.3%Reduced
Rhumbline Advisers160,448$12.8M0.01%+6,634+4.3%Added
Manufacturers Life Insurance Company, The171,543$13.7M0.01%+2,133+1.3%Added
a16z Perennial Management, L.P.182,918$14.6M1.16%+182,918New
Susquehanna International Group, LLP183,221$14.6M0.02%+65,013+55.0%Added
Verition Fund Management LLC189,333$15.1M0.08%+53,884+39.8%Added
Baillie Gifford & Co194,959$15.5M0.01%+194,959New
Decheng Capital LLC200,000$15.9M2.14%−10,000−4.8%Reduced
Marsico Capital Management LLC219,460$17.5M0.49%+219,460New
Catalyst Funds Management Pty Ltd223,569$17.8M4.13%+13,400+6.4%Added
Ensign Peak Advisors, Inc235,808$18.8M0.03%−12,670−5.1%Reduced
Alyeska Investment Group, L.P.239,097$19.0M0.05%+239,097New