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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Relay Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+12 vs. Q4 2024
Shares held
167.3M
+8.03M (+5.0%) vs. Q4 2024
Total value
$438.1M
−$218.3M (−33.3%) vs. Q4 2024
New holders
36
73 more added
Sold out
24
59 more reduced

4 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 208 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ1 2025: $438.1M
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding RLAY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ensign Peak Advisors, Inc64,900$170.0K0.00%00.0%Unchanged
MetLife Investment Management65,272$171.0K0.00%−8,894−12.0%Reduced
Los Angeles Capital Management LLC65,340$171.2K0.00%+12,570+23.8%Added
Polymer Capital Management (US) LLC69,404$181.8K0.05%+69,404New
Deutsche Bank AG70,769$185.4K0.00%−11,691−14.2%Reduced
EntryPoint Capital, LLC71,486$187.3K0.09%+49,161+220.2%Added
Point72 Asia (Singapore) Pte. Ltd.71,649$187.7K0.05%+71,649New
Wells Fargo & Company75,514$197.8K0.00%+4,089+5.7%Added
XTX Topco Ltd79,913$209.4K0.01%+20,161+33.7%Added
Martingale Asset Management L P80,371$210.6K0.01%00.0%Unchanged
Intech Investment Management LLC81,428$213.3K0.00%+33,783+70.9%Added
Tudor Investment Corp Et Al83,158$217.9K0.00%−3,199−3.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.84,069$221.2K0.00%+5,238+6.6%Added
Omers Administration Corp85,200$223.2K0.00%+85,200New
NEOS Investment Management LLC89,110$233.5K0.00%+24,455+37.8%Added
Tema ETFs LLC89,110$233.5K0.07%+24,455+37.8%Added
ICONIQ Capital, LLC94,697$248.1K0.00%00.0%Unchanged
Federated Hermes, Inc.96,313$252.3K0.00%+46,213+92.2%Added
Private Capital Advisors, Inc.100,000$262.0K0.03%+100,000New
Persistent Asset Partners Ltd100,484$263.3K0.23%−45,344−31.1%Reduced
State of Wisconsin Investment Board100,555$263.5K0.00%+33,377+49.7%Added
Walleye Capital LLC101,548$266.1K0.00%−825,589−89.0%Reduced
California State Teachers Retirement System106,287$278.5K0.00%00.0%Unchanged
Jane Street Group, LLC111,472$292.1K0.00%+35,962+47.6%Added
HSBC Holdings PLC116,408$300.0K0.00%+4,639+4.2%Added
Squarepoint Ops LLC114,619$300.3K0.00%−47,969−29.5%Reduced
Legal & General Group Plc129,215$338.5K0.00%+4,329+3.5%Added
Verition Fund Management LLC139,244$364.8K0.00%+48,770+53.9%Added
Congress Asset Management Co156,202$409.2K0.00%−1,283−0.8%Reduced
TD Asset Management Inc156,456$409.9K0.00%00.0%Unchanged
Thrivent Financial for Lutherans166,668$436.0K0.00%00.0%Unchanged
Alliancebernstein L.P.168,281$440.9K0.00%+30,000+21.7%Added
Franklin Resources Inc171,080$448.2K0.00%+112,275+190.9%Added
Rhumbline Advisers174,125$456.2K0.00%+2,681+1.6%Added
Raymond James Financial Inc184,533$483.5K0.00%−4,513−2.4%Reduced
Invesco Ltd.184,831$484.3K0.00%+65,414+54.8%Added
Congress Wealth Management LLC186,063$487.5K0.01%+186,063New
Raiffeisen Bank International AG180,000$489.6K0.01%00.0%Unchanged
Parkman Healthcare Partners LLC188,052$492.7K0.06%−312,496−62.4%Reduced
Schonfeld Strategic Advisors LLC204,055$534.6K0.00%−150,445−42.4%Reduced
Rafferty Asset Management, LLC205,068$537.3K0.00%−44,493−17.8%Reduced
Manufacturers Life Insurance Company, The205,579$538.6K0.00%−13,293−6.1%Reduced
Man Group plc205,721$539.0K0.00%+32,116+18.5%Added
Boothbay Fund Management, LLC226,737$594.1K0.02%+12,338+5.8%Added
Swiss National Bank227,000$594.7K0.00%+7,400+3.4%Added
Balyasny Asset Management LLC231,442$606.4K0.00%−460,837−66.6%Reduced
HighTower Advisors, LLC247,176$647.6K0.00%+47,433+23.7%Added
Susquehanna International Group, LLP256,783$672.8K0.00%+180,465+236.5%Added
Citigroup Inc260,313$682.0K0.00%+54,637+26.6%Added
UBS Group AG275,558$722.0K0.00%−67,688−19.7%Reduced
HarbourVest Partners LLC296,402$776.6K0.51%00.0%Unchanged
UBS Asset Management Americas Inc301,550$790.1K0.00%+68,968+29.7%Added
American Century Companies Inc308,752$808.9K0.00%+36,586+13.4%Added
Nuveen, LLC320,395$839.4K0.00%+320,395New
Trexquant Investment LP324,469$850.1K0.01%−653,668−66.8%Reduced
Bank of New York Mellon Corp329,905$864.4K0.00%+1,008+0.3%Added
Citadel Advisors LLC337,268$883.6K0.00%−349,610−50.9%Reduced
Susquehanna Fundamental Investments, LLC356,165$933.2K0.02%+9,877+2.9%Added
AQR Capital Management LLC364,946$956.2K0.00%+38,812+11.9%Added
HRT Financial LP368,579$965.0K0.01%+368,579New
Ameriprise Financial Inc372,353$975.6K0.00%+66,912+21.9%Added
UBS Oconnor LLC382,900$1.00M0.02%+52,201+15.8%Added
Prudential Financial Inc393,375$1.03M0.00%−156,270−28.4%Reduced
Dark Forest Capital Management LP405,995$1.06M0.05%+405,995New
Diadema Partners LP426,346$1.12M0.89%−79,432−15.7%Reduced
Voloridge Investment Management, LLC431,150$1.13M0.00%−192,189−30.8%Reduced
Rhenman & Partners Asset Management AB460,000$1.21M0.14%00.0%Unchanged
Barclays PLC469,171$1.23M0.00%+155,969+49.8%Added
ArrowMark Colorado Holdings LLC541,124$1.42M0.02%00.0%Unchanged
Bank of America Corp554,428$1.45M0.00%+97,134+21.2%Added
Candriam Luxembourg S.C.A.580,136$1.52M0.01%−1,149,063−66.5%Reduced
Bessemer Group Inc584,530$1.53M0.00%+670.0%Added
Polygon Management Ltd.619,000$1.62M0.52%+619,000New
EcoR1 Capital, LLC641,426$1.68M0.10%00.0%Unchanged
Acadian Asset Management LLC682,028$1.78M0.01%+653,081+2,256.1%Added
Ikarian Capital, LLC743,308$1.95M0.63%+50,000+7.2%Added
Two Sigma Advisers, LP751,200$1.97M0.00%+112,300+17.6%Added
Two Sigma Investments, LP843,856$2.21M0.00%+27,771+3.4%Added
Algert Global LLC931,251$2.44M0.06%−63,672−6.4%Reduced
Foresite Capital Management IV, LLC1,000,000$2.62M2.36%00.0%Unchanged
Charles Schwab Investment Management Inc1,064,858$2.79M0.00%+54,051+5.3%Added
Northern Trust Corp1,142,928$2.99M0.00%−27,051−2.3%Reduced
Baker Bros. Advisors LP1,160,117$3.04M0.03%00.0%Unchanged
Woodline Partners LP1,518,561$3.98M0.03%+1,241,657+448.4%Added
Alphabet Inc.1,568,753$4.11M0.26%00.0%Unchanged
Morgan Stanley1,593,186$4.17M0.00%+292,416+22.5%Added
Goldman Sachs Group Inc2,077,995$5.44M0.00%−627,974−23.2%Reduced
Finepoint Capital LP2,117,646$5.55M0.94%−58,000−2.7%Reduced
Renaissance Technologies LLC2,276,110$5.96M0.01%+726,920+46.9%Added
MPM Oncology Impact Management LP2,295,924$6.02M1.03%+27,099+1.2%Added
Eventide Asset Management, LLC2,682,083$7.03M0.14%00.0%Unchanged
Dimensional Fund Advisors LP2,799,091$7.33M0.00%−165,906−5.6%Reduced
Millennium Management LLC2,942,875$7.71M0.01%+374,491+14.6%Added
Kynam Capital Management, LP3,063,292$8.03M0.69%+2,063,292+206.3%Added
Geode Capital Management, LLC3,070,118$8.05M0.00%+39,961+1.3%Added
Price T Rowe Associates Inc3,477,791$9.11M0.00%+156,050+4.7%Added
Nextech Invest, Ltd.3,846,409$10.1M2.34%+3,846,409New
Norges Bank4,635,137$12.1M0.00%−1,146,741−19.8%Reduced
JPMorgan Chase & Co4,909,771$12.9M0.00%−68,672−1.4%Reduced
State Street Corp5,159,192$13.5M0.00%−120,534−2.3%Reduced