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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 13 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Relay Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
131
0 vs. Q3 2021
Shares held
111.0M
+19.2M (+20.9%) vs. Q3 2021
Total value
$3.41B
+$513.0M (+17.7%) vs. Q3 2021
New holders
18
70 more added
Sold out
18
20 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 131 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ4 2021: $3.41B
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q3 2021.

Institutions holding RLAY in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Allstate Corp8,600$264.0K0.01%+8,600New
Teacher Retirement System of Texas7,956$244.0K0.00%+7,956New
Cubist Systematic Strategies, LLC7,645$235.0K0.00%−58,673−88.5%Reduced
Tower Research Capital LLC (TRC)7,609$234.0K0.00%−1,131−12.9%Reduced
American Financial Group Inc7,484$230.0K0.06%00.0%Unchanged
EDBI Pte Ltd7,484$230.0K0.12%+7,484New
XTX Topco Ltd7,174$220.0K0.12%+7,174New
Renaissance Technologies LLC7,000$215.0K0.00%−145,588−95.4%Reduced
Vontobel Holding Ltd.6,580$202.0K0.00%+6,580New
Virtus ETF Advisers LLC5,885$181.0K0.07%−328−5.3%Reduced
Public Employees Retirement Association of Colorado5,888$181.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.5,408$166.0K0.01%+818+17.8%Added
DuPont Capital Management Corp5,206$160.0K0.01%−2,076−28.5%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)5,112$157.0K0.00%+2,313+82.6%Added
Ensign Peak Advisors, Inc4,660$143.0K0.00%+4,660New
STRS Ohio3,100$95.0K0.00%00.0%Unchanged
Marshall Wace, LLP2,499$77.0K0.00%−17,231−87.3%Reduced
Nisa Investment Advisors, LLC2,586$57.0K0.00%+1,457+129.1%Added
Great West Life Assurance Co1,675$51.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,000$31.0K0.00%00.0%Unchanged
HighMark Wealth Management LLC905$28.0K0.02%−1,700−65.3%Reduced
Russell Investments Group, Ltd.871$26.0K0.00%00.0%Unchanged
Macquarie Group Ltd543$17.0K0.00%00.0%Unchanged
Dark Forest Capital Management LP453$14.0K0.01%−3,782−89.3%Reduced
Daiwa Securities Group Inc.317$10.0K0.00%00.0%Unchanged
Quantbot Technologies LP100$3.00K0.00%−4,700−97.9%Reduced
Your Advocates Ltd., LLP100$3.00K0.00%00.0%Unchanged
Parallel Advisors, LLC71$2.00K0.00%+71New
Bell Investment Advisors, Inc35$1.00K0.00%+4+12.9%Added
Covestor Ltd19$1.00K0.00%+19New
Captrust Financial Advisors10$00.00%+10New
Two Sigma Investments, LP0$00.00%−191,891−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−70,253−100.0%Sold out
Alpine Global Management, LLC0$00.00%−59,374−100.0%Sold out
First Light Asset Management, LLC0$00.00%−51,848−100.0%Sold out
Jane Street Group, LLC0$00.00%−19,364−100.0%Sold out
Janus Henderson Group PLC0$00.00%−17,004−100.0%Sold out
Winton Group Ltd0$00.00%−13,964−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−11,340−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−11,267−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−9,836−100.0%Sold out
Virtu Financial LLC0$00.00%−7,512−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−7,394−100.0%Sold out
Aigen Investment Management, LP0$00.00%−7,328−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−7,300−100.0%Sold out
Penserra Capital Management LLC0$00.00%−2,115−100.0%Sold out
Signaturefd, LLC0$00.00%−495−100.0%Sold out
TCI Wealth Advisors, Inc.0$00.00%−146−100.0%Sold out
Jacobi Capital Management LLC0$00.00%−94−100.0%Sold out
Marshall Wace North America L.P.––––Not filed