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Repligen Corp

RGEN
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000730272

In the last 90 days, Repligen Corp insiders filed 0 open-market purchases and 5 sales; 481 institutions reported holding it in 13F filings for Q2 2026, worth $9.00B in total; 3 superinvestors hold it, including Maverick Capital and Duquesne Family Office.

13F holders, Q4 2025

Institutional positions in Repligen Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
475
+34 vs. Q3 2025
Shares held
62.5M
+2.82M (+4.7%) vs. Q3 2025
Total value
$10.2B
+$2.26B (+28.3%) vs. Q3 2025
New holders
96
150 more added
Sold out
62
145 more reduced

12 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGEN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 475 institutions
Q1 2021: 459 institutionsQ2 2021: 430 institutionsQ3 2021: 481 institutionsQ4 2021: 508 institutionsQ1 2022: 450 institutionsQ2 2022: 406 institutionsQ3 2022: 434 institutionsQ4 2022: 443 institutionsQ1 2023: 448 institutionsQ2 2023: 448 institutionsQ3 2023: 440 institutionsQ4 2023: 467 institutionsQ1 2024: 487 institutionsQ2 2024: 455 institutionsQ3 2024: 445 institutionsQ4 2024: 431 institutionsQ1 2025: 441 institutionsQ2 2025: 446 institutionsQ3 2025: 453 institutionsQ4 2025: 475 institutionsQ1 2026: 445 institutionsQ2 2026: 481 institutions
Value heldQ4 2025: $10.2B
Q1 2021: $8.88BQ2 2021: $9.28BQ3 2021: $13.6BQ4 2021: $12.5BQ1 2022: $9.15BQ2 2022: $8.17BQ3 2022: $9.56BQ4 2022: $9.06BQ1 2023: $9.06BQ2 2023: $7.74BQ3 2023: $9.08BQ4 2023: $10.4BQ1 2024: $10.3BQ2 2024: $7.06BQ3 2024: $8.25BQ4 2024: $8.09BQ1 2025: $7.33BQ2 2025: $7.22BQ3 2025: $8.00BQ4 2025: $10.2BQ1 2026: $7.75BQ2 2026: $9.00B
Institutions holding RGEN and their total value by quarter
QuarterHoldersValue
Q2 2026481$9.00B
Q1 2026445$7.75B
Q4 2025475$10.2B
Q3 2025453$8.00B
Q2 2025446$7.22B
Q1 2025441$7.33B
Q4 2024431$8.09B
Q3 2024445$8.25B
Q2 2024455$7.06B
Q1 2024487$10.3B
Q4 2023467$10.4B
Q3 2023440$9.08B
Q2 2023448$7.74B
Q1 2023448$9.06B
Q4 2022443$9.06B
Q3 2022434$9.56B
Q2 2022406$8.17B
Q1 2022450$9.15B
Q4 2021508$12.5B
Q3 2021481$13.6B
Q2 2021430$9.28B
Q1 2021459$8.88B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Repligen Corp; share changes are against Q3 2025.

Institutions holding RGEN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Summit Trail Advisors, LLC7,662$1.26M0.02%+388+5.3%Added
Cinctive Capital Management LP7,638$1.25M0.07%−17,782−70.0%Reduced
Pictet Asset Management Holding SA7,544$1.24M0.00%+308+4.3%Added
Glenmede Trust Co NA7,498$1.23M0.01%+7,498New
Groupama Asset Managment7,437$1.22M0.02%+5,903+384.8%Added
First Manhattan Co6,550$1.07M0.00%00.0%Unchanged
MML Investors Services, LLC6,172$1.01M0.00%+2,212+55.9%Added
Jefferies Financial Group Inc.6,156$1.01M0.01%+6,156New
Commonwealth Equity Services, LLC6,143$1.01M0.00%−42−0.7%Reduced
Alpine Woods Capital Investors, LLC6,136$1.01M0.24%+6,136New
JustInvest LLC5,763$944.3K0.01%+667+13.1%Added
Portside Wealth Group, LLC5,713$936.1K0.13%+3,511+159.4%Added
Creative Planning5,684$931.4K0.00%+1,679+41.9%Added
Xponance, Inc.5,601$917.8K0.01%−993−15.1%Reduced
Entropy Technologies, LP5,493$900.1K0.05%+2,710+97.4%Added
Gibbs Wealth Management5,360$894.2K0.22%+5,360New
Dana Investment Advisors, Inc.5,274$864.2K0.03%−628−10.6%Reduced
Kensington Investment Counsel, LLC5,241$858.8K0.35%−2,851−35.2%Reduced
State of Alaska, Department of Revenue5,234$857.0K0.01%−365−6.5%Reduced
Two Sigma Securities, LLC5,226$856.3K0.12%+5,226New
XTX Topco Ltd5,148$843.6K0.02%+5,148New
Atria Investments LLC5,052$827.8K0.01%+2,000+65.5%Added
Benin Management CORP5,000$819.3K0.18%00.0%Unchanged
Alliance Wealth Advisors, LLC4,810$788.2K0.17%−1,695−26.1%Reduced
Toroso Investments, LLC4,717$772.9K0.00%−3,077−39.5%Reduced
New York Life Investment Management LLC4,650$761.9K0.01%−680−12.8%Reduced
Wealth Enhancement Advisory Services, LLC4,354$750.0K0.00%+353+8.8%Added
The PNC Financial Services Group, Inc.4,464$731.5K0.00%+1,093+32.4%Added
D L Carlson Investment Group Inc4,463$731.3K0.12%−521−10.5%Reduced
Federated Hermes, Inc.4,255$697.2K0.00%−469−9.9%Reduced
Advisors Asset Management, Inc.4,251$696.6K0.01%−4,359−50.6%Reduced
Federation des caisses Desjardins du Quebec4,113$674.0K0.00%+605+17.2%Added
Norden Group LLC4,112$673.8K0.07%+1,744+73.6%Added
Mitsubishi UFJ Asset Management (UK) Ltd.4,000$655.0K0.32%00.0%Unchanged
Graham Capital Management, L.P.3,908$640.4K0.02%+1,389+55.1%Added
David Loasby3,770$634.9K0.04%−1,408−27.2%Reduced
Crossmark Global Holdings, Inc.3,859$632.3K0.01%+408+11.8%Added
Hemenway Trust Co LLC3,850$630.9K0.05%−200−4.9%Reduced
Securian Asset Management, Inc3,842$629.5K0.02%−100−2.5%Reduced
Verdence Capital Advisors LLC3,802$623.0K0.04%−1,108−22.6%Reduced
Fifth Third Bancorp3,772$618.1K0.00%+622+19.7%Added
Qsemble Capital Management, LP3,728$610.9K0.05%+291+8.5%Added
Truist Financial Corp3,672$601.7K0.00%+1,237+50.8%Added
Intech Investment Management LLC3,625$594.0K0.01%−49,979−93.2%Reduced
China Universal Asset Management Co., Ltd.3,600$589.9K0.05%−1,400−28.0%Reduced
HighTower Advisors, LLC3,436$563.0K0.00%+529+18.2%Added
CI Private Wealth, LLC3,396$558.4K0.00%−904−21.0%Reduced
Diversify Advisory Services, LLC3,439$557.2K0.02%+425+14.1%Added
Calamos Advisors LLC3,362$550.9K0.00%+3,362New
Azzad Asset Management Inc3,314$543.1K0.05%−4,869−59.5%Reduced
Drive Wealth Management, LLC3,292$539.4K0.11%−313−8.7%Reduced
Silvercrest Asset Management Group LLC3,125$512.1K0.00%+3,125New
Allianz Asset Management GmbH3,091$506.5K0.00%+3,091New
QRG Capital Management, Inc.3,047$499.3K0.01%+626+25.9%Added
Quadrant Capital Group LLC2,956$484.4K0.01%+1,047+54.8%Added
Granite Investment Partners, LLC2,940$481.7K0.03%−8,155−73.5%Reduced
Susquehanna International Group, LLP2,939$481.6K0.00%−34,406−92.1%Reduced
Jones Financial Companies LLLP2,803$459.3K0.00%−509−15.4%Reduced
Washington Capital Management Inc2,800$458.8K0.37%00.0%Unchanged
Utah Retirement Systems2,784$456.2K0.00%00.0%Unchanged
Sterling Capital Management LLC2,776$454.9K0.01%−86−3.0%Reduced
Whalen Wealth Management Inc.2,747$450.1K0.24%−664−19.5%Reduced
Cerity Partners LLC2,718$445.4K0.00%+157+6.1%Added
Total Clarity Wealth Management, Inc.2,680$439.1K0.11%00.0%Unchanged
Trust Point Inc.2,680$439.1K0.03%+54+2.1%Added
Envestnet Portfolio Solutions, Inc.2,650$434.2K0.00%+2,650New
Maryland State Retirement & Pension System2,604$426.7K0.01%00.0%Unchanged
Knollwood Investment Advisory, LLC2,500$409.6K0.04%00.0%Unchanged
Swiss Life Asset Management Ltd2,477$405.9K0.00%00.0%Unchanged
Argent Trust Co2,458$402.8K0.01%+2,458New
Premier Fund Managers Ltd2,399$400.0K0.02%00.0%Unchanged
Integrated Investment Consultants, LLC2,360$386.7K0.08%00.0%Unchanged
O'Shaughnessy Asset Management, LLC2,335$382.6K0.00%+630+37.0%Added
State of Wyoming2,247$368.2K0.04%−751−25.1%Reduced
Deerfield Management Company, L.P. (Series C)2,199$360.3K0.00%−10,710−83.0%Reduced
Lazard Asset Management LLC2,148$352.0K0.00%+2,148New
Wealth Alliance2,142$351.0K0.03%+113+5.6%Added
ProShare Advisors LLC2,121$347.5K0.00%−128−5.7%Reduced
HSBC Holdings PLC2,093$343.1K0.00%−203−8.8%Reduced
Tower Research Capital LLC (TRC)2,074$339.8K0.01%+622+42.8%Added
Vestmark Advisory Solutions, Inc.2,050$335.9K0.00%+2,050New
M&T Bank Corp2,031$333.2K0.00%+2,031New
Angeles Wealth Management, LLC2,032$333.0K0.02%+125+6.6%Added
Coldstream Capital Management Inc1,992$326.4K0.00%+101+5.3%Added
Malaga Cove Capital, LLC1,966$322.1K0.11%−16−0.8%Reduced
Private Advisor Group, LLC1,945$318.7K0.00%+1,945New
Canada Pension Plan Investment Board1,900$311.3K0.00%−14,100−88.1%Reduced
Shelton Capital Management1,870$306.4K0.01%00.0%Unchanged
Claret Asset Management Corp1,853$304.0K0.04%−4−0.2%Reduced
North Dakota State Investment Board1,849$303.0K0.01%+1,849New
MidFirst Bank1,823$298.7K0.02%+1,823New
Skopos Labs, Inc.1,796$297.7K0.01%+1,796New
Fort Washington Investment Advisors Inc1,815$297.4K0.00%00.0%Unchanged
WealthCare Investment Partners, LLC1,800$295.8K0.09%00.0%Unchanged
Commerce Bank1,765$289.2K0.00%−61−3.3%Reduced
Farringdon Capital, Ltd.1,761$288.6K0.07%+1,761New
Global Retirement Partners, LLC1,755$287.6K0.01%+1,407+404.3%Added
Summitry LLC1,741$285.3K0.01%+244+16.3%Added
CIBC Asset Management Inc1,739$285.0K0.00%00.0%Unchanged
Investment Advisory Group, LLC1,723$282.3K0.07%00.0%Unchanged