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Replimune Group, Inc.

REPL
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001737953

In the last 90 days, Replimune Group, Inc. insiders filed 0 open-market purchases and 5 sales; 199 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Replimune Group, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
165
+4 vs. Q3 2025
Shares held
79.7M
−3.12M (−3.8%) vs. Q3 2025
Total value
$775.2M
+$427.7M (+123.1%) vs. Q3 2025
New holders
36
58 more added
Sold out
32
52 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting REPL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 165 institutions
Q1 2021: 108 institutionsQ2 2021: 110 institutionsQ3 2021: 101 institutionsQ4 2021: 99 institutionsQ1 2022: 107 institutionsQ2 2022: 102 institutionsQ3 2022: 106 institutionsQ4 2022: 135 institutionsQ1 2023: 140 institutionsQ2 2023: 141 institutionsQ3 2023: 127 institutionsQ4 2023: 140 institutionsQ1 2024: 150 institutionsQ2 2024: 149 institutionsQ3 2024: 144 institutionsQ4 2024: 157 institutionsQ1 2025: 167 institutionsQ2 2025: 175 institutionsQ3 2025: 163 institutionsQ4 2025: 165 institutionsQ1 2026: 180 institutionsQ2 2026: 199 institutions
Value heldQ4 2025: $775.2M
Q1 2021: $1.06BQ2 2021: $1.34BQ3 2021: $1.05BQ4 2021: $1.05BQ1 2022: $665.0MQ2 2022: $700.2MQ3 2022: $703.9MQ4 2022: $1.31BQ1 2023: $949.0MQ2 2023: $1.27BQ3 2023: $970.9MQ4 2023: $556.8MQ1 2024: $547.8MQ2 2024: $638.1MQ3 2024: $766.7MQ4 2024: $943.2MQ1 2025: $799.3MQ2 2025: $752.1MQ3 2025: $347.5MQ4 2025: $775.2MQ1 2026: $619.2MQ2 2026: $1.06B
Institutions holding REPL and their total value by quarter
QuarterHoldersValue
Q2 2026199$1.06B
Q1 2026180$619.2M
Q4 2025165$775.2M
Q3 2025163$347.5M
Q2 2025175$752.1M
Q1 2025167$799.3M
Q4 2024157$943.2M
Q3 2024144$766.7M
Q2 2024149$638.1M
Q1 2024150$547.8M
Q4 2023140$556.8M
Q3 2023127$970.9M
Q2 2023141$1.27B
Q1 2023140$949.0M
Q4 2022135$1.31B
Q3 2022106$703.9M
Q2 2022102$700.2M
Q1 2022107$665.0M
Q4 202199$1.05B
Q3 2021101$1.05B
Q2 2021110$1.34B
Q1 2021108$1.06B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Replimune Group, Inc.; share changes are against Q3 2025.

Institutions holding REPL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP11,045,336$107.4M0.63%00.0%Unchanged
Price T Rowe Associates Inc8,262,296$80.3M0.01%−44,137−0.5%Reduced
RTW Investments, LP7,140,352$69.4M0.70%+744,620+11.6%Added
BlackRock, Inc.6,069,633$59.0M0.00%+293,737+5.1%Added
Vanguard Group Inc3,776,198$36.7M0.00%+296,803+8.5%Added
State Street Corp3,693,107$35.9M0.00%+768,982+26.3%Added
FMR LLC2,981,580$29.0M0.00%+1,620,501+119.1%Added
FCPM III Services B.V.2,808,368$27.3M3.58%−1,350,000−32.5%Reduced
D. E. Shaw & Co., Inc.2,575,042$25.0M0.02%+2,171,547+538.2%Added
Toronto Dominion Bank2,229,527$21.7M0.04%+857,475+62.5%Added
Erste Asset Management GmbH2,120,000$20.6M0.17%+490,000+30.1%Added
Adage Capital Partners GP, L.L.C.1,807,368$17.6M0.03%+1,807,368New
Geode Capital Management, LLC1,750,194$17.0M0.00%+54,746+3.2%Added
Commodore Capital LP1,425,000$13.9M0.92%+1,425,000New
Rosalind Advisors, Inc.1,410,497$13.7M5.26%+1,410,497New
ADAR1 Capital Management, LLC1,241,322$12.1M0.90%+262,428+26.8%Added
Dimensional Fund Advisors LP1,119,357$10.9M0.00%−132,144−10.6%Reduced
Redmile Group, LLC1,099,756$10.7M0.79%+563,938+105.2%Added
JPMorgan Chase & Co925,173$8.99M0.00%+887,157+2,333.6%Added
Millennium Management LLC834,562$8.11M0.01%−755,183−47.5%Reduced
Morgan Stanley814,888$7.92M0.00%−560,631−40.8%Reduced
Boxer Capital Management, LLC750,000$7.29M1.60%−300,000−28.6%Reduced
Jefferies Financial Group Inc.714,226$6.94M0.06%+714,226New
Goldman Sachs Group Inc658,096$6.40M0.00%−476,655−42.0%Reduced
Invesco Ltd.613,015$5.96M0.00%+458,714+297.3%Added
Susquehanna International Group, LLP606,844$5.90M0.01%+606,844New
UBS Group AG604,313$5.87M0.00%−297,317−33.0%Reduced
Charles Schwab Investment Management Inc587,890$5.71M0.00%+72,490+14.1%Added
Jane Street Group, LLC584,330$5.68M0.01%+550.0%Added
Nan Fung Trinity (HK) Ltd575,527$5.59M0.44%+110,000+23.6%Added
Woodline Partners LP570,988$5.55M0.02%−285,000−33.3%Reduced
Northern Trust Corp539,600$5.24M0.00%−74,593−12.1%Reduced
BNP Paribas Arbitrage, SA460,704$4.48M0.00%+446,942+3,247.7%Added
Two Sigma Investments, LP444,074$4.32M0.01%+286,575+182.0%Added
Renaissance Technologies LLC405,053$3.94M0.01%+405,053New
Quinn Opportunity Partners LLC392,915$3.82M0.17%−257,806−39.6%Reduced
Jump Financial, LLC296,843$2.89M0.04%+53,076+21.8%Added
Barclays PLC292,185$2.84M0.00%−163,677−35.9%Reduced
TD Asset Management Inc266,484$2.59M0.00%−17,568−6.2%Reduced
Omega Fund Management, LLC248,672$2.42M0.84%00.0%Unchanged
Diadema Partners LP230,997$2.25M1.34%+230,997New
Caption Management, LLC228,570$2.22M0.10%+58,570+34.5%Added
Bank of America Corp215,330$2.09M0.00%+106,046+97.0%Added
Bank of New York Mellon Corp209,222$2.03M0.00%+7,915+3.9%Added
Wellington Management Group LLP208,669$2.03M0.00%−18,347−8.1%Reduced
HRT Financial LP183,592$1.78M0.01%+9,541+5.5%Added
Manufacturers Life Insurance Company, The178,911$1.75M0.00%−38,675−17.8%Reduced
Trexquant Investment LP180,494$1.75M0.02%+180,494New
Resolute Capital Asset Partners LLC175,000$1.70M0.82%+175,000New
Citadel Advisors LLC158,359$1.54M0.00%+38,127+31.7%Added
Hudson Bay Capital Management LP153,650$1.49M0.01%+153,650New
American Century Companies Inc148,086$1.44M0.00%+8,350+6.0%Added
Rafferty Asset Management, LLC140,909$1.37M0.00%+32,317+29.8%Added
Tudor Investment Corp Et Al128,380$1.25M0.01%+107,615+518.3%Added
SummitTX Capital, L.P.108,803$1.06M0.03%+108,803New
Marshall Wace, LLP93,585$909.6K0.00%+93,585New
Wells Fargo & Company90,724$881.8K0.00%−64,656−41.6%Reduced
Rhumbline Advisers89,311$868.1K0.00%−10,004−10.1%Reduced
Point72 Asset Management, L.P.72,210$701.9K0.00%−3,557,692−98.0%Reduced
SG Americas Securities, LLC71,955$699.0K0.00%−26,776−27.1%Reduced
Squarepoint Ops LLC67,271$653.9K0.00%−4,536−6.3%Reduced
Susquehanna Portfolio Strategies, LLC66,875$650.0K0.01%+66,875New
Nan Fung Group Holdings Ltd63,719$619.3K0.55%00.0%Unchanged
Alliancebernstein L.P.62,140$604.0K0.00%−1,400−2.2%Reduced
ACT Capital Management, LLC61,500$597.8K0.48%+61,500New
Persistent Asset Partners Ltd61,488$597.7K0.29%+61,488New
Nuveen, LLC57,614$560.0K0.00%00.0%Unchanged
Acadian Asset Management LLC56,723$550.0K0.00%−16,917−23.0%Reduced
Deutsche Bank AG53,944$524.3K0.00%−485,623−90.0%Reduced
Brevan Howard Capital Management LP52,961$514.8K0.01%00.0%Unchanged
Profund Advisors LLC52,145$506.8K0.02%+28,476+120.3%Added
NEOS Investment Management LLC52,052$505.9K0.00%+9,086+21.1%Added
Tema ETFs LLC51,282$498.5K0.04%+8,316+19.4%Added
Raymond James Financial Inc47,364$460.4K0.00%−139,630−74.7%Reduced
Los Angeles Capital Management LLC44,045$451.5K0.00%+1,271+3.0%Added
Creative Planning45,161$439.0K0.00%+23,969+113.1%Added
Aquatic Capital Management LLC44,632$433.8K0.01%+44,632New
State of Wisconsin Investment Board41,181$400.3K0.00%−217,779−84.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.40,352$393.0K0.00%+2,620+6.9%Added
Suvretta Capital Management, LLC36,038$350.3K0.01%+36,038New
Schonfeld Strategic Advisors LLC35,220$342.3K0.00%+35,220New
Advisor Group Holdings, Inc.35,200$342.1K0.00%+9,127+35.0%Added
MetLife Investment Management34,328$333.7K0.00%−6,210−15.3%Reduced
XTX Topco Ltd33,163$322.3K0.01%+33,163New
Voya Investment Management LLC32,093$311.9K0.00%+19,645+157.8%Added
Two Sigma Advisers, LP30,700$298.4K0.00%+30,700New
Gsa Capital Partners LLP29,147$283.0K0.02%+9,861+51.1%Added
Quest Partners LLC28,080$272.9K0.02%+3,050+12.2%Added
Virtus Investment Advisers, Inc.26,133$254.0K0.07%+14,622+127.0%Added
Dynamic Technology Lab Private Ltd25,905$252.0K0.06%+5,781+28.7%Added
Balyasny Asset Management LLC25,319$246.1K0.00%−2,602,781−99.0%Reduced
Intech Investment Management LLC24,704$240.1K0.00%00.0%Unchanged
Ballentine Partners, LLC23,665$230.0K0.00%+1,721+7.8%Added
Nisa Investment Advisors, LLC20,952$203.7K0.00%+20,058+2,243.6%Added
Citigroup Inc20,194$196.3K0.00%+13,067+183.3%Added
HighTower Advisors, LLC20,123$195.6K0.00%+3,994+24.8%Added
Axq Capital, LP19,862$193.1K0.04%+19,862New
Police & Firemen's Retirement System of New Jersey18,445$179.3K0.00%00.0%Unchanged
9823 Capital, L.P.18,332$178.2K0.12%+18,332New
Centiva Capital, LP18,000$175.0K0.01%+18,000New