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Regeneron Pharmaceuticals, Inc.

REGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000872589

In the last 90 days, Regeneron Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 5 sales; 1,342 institutions reported holding it in 13F filings for Q2 2026, worth $57.1B in total; Southeastern Asset Management (Longleaf) is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Regeneron Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,387
+167 vs. Q3 2025
Shares held
91.6M
+4.76M (+5.5%) vs. Q3 2025
Total value
$70.7B
+$21.9B (+44.9%) vs. Q3 2025
New holders
273
502 more added
Sold out
106
457 more reduced

23 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting REGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 1,387 institutions
Q1 2021: 926 institutionsQ2 2021: 975 institutionsQ3 2021: 1,022 institutionsQ4 2021: 1,081 institutionsQ1 2022: 1,097 institutionsQ2 2022: 1,066 institutionsQ3 2022: 1,081 institutionsQ4 2022: 1,161 institutionsQ1 2023: 1,196 institutionsQ2 2023: 1,168 institutionsQ3 2023: 1,180 institutionsQ4 2023: 1,274 institutionsQ1 2024: 1,313 institutionsQ2 2024: 1,335 institutionsQ3 2024: 1,393 institutionsQ4 2024: 1,320 institutionsQ1 2025: 1,290 institutionsQ2 2025: 1,201 institutionsQ3 2025: 1,243 institutionsQ4 2025: 1,387 institutionsQ1 2026: 1,401 institutionsQ2 2026: 1,342 institutions
Value heldQ4 2025: $70.7B
Q1 2021: $42.3BQ2 2021: $49.6BQ3 2021: $54.5BQ4 2021: $56.9BQ1 2022: $64.5BQ2 2022: $55.0BQ3 2022: $64.0BQ4 2022: $66.9BQ1 2023: $76.1BQ2 2023: $66.2BQ3 2023: $75.1BQ4 2023: $80.3BQ1 2024: $89.3BQ2 2024: $98.9BQ3 2024: $97.5BQ4 2024: $66.6BQ1 2025: $59.0BQ2 2025: $46.9BQ3 2025: $49.0BQ4 2025: $70.7BQ1 2026: $69.8BQ2 2026: $57.1B
Institutions holding REGN and their total value by quarter
QuarterHoldersValue
Q2 20261,342$57.1B
Q1 20261,401$69.8B
Q4 20251,387$70.7B
Q3 20251,243$49.0B
Q2 20251,201$46.9B
Q1 20251,290$59.0B
Q4 20241,320$66.6B
Q3 20241,393$97.5B
Q2 20241,335$98.9B
Q1 20241,313$89.3B
Q4 20231,274$80.3B
Q3 20231,180$75.1B
Q2 20231,168$66.2B
Q1 20231,196$76.1B
Q4 20221,161$66.9B
Q3 20221,081$64.0B
Q2 20221,066$55.0B
Q1 20221,097$64.5B
Q4 20211,081$56.9B
Q3 20211,022$54.5B
Q2 2021975$49.6B
Q1 2021926$42.3B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Regeneron Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding REGN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Dana Investment Advisors, Inc.8,395$6.48M0.19%+3,082+58.0%Added
Cardinal Capital Management8,406$6.49M0.86%−25−0.3%Reduced
Game Creek Capital, LP8,435$6.51M2.47%+3,510+71.3%Added
Fiduciary Trust Co8,466$6.53M0.07%+615+7.8%Added
Stratos Wealth Advisors, LLC8,473$6.54M0.32%+481+6.0%Added
Simplex Trading, LLC8,559$6.61M0.19%+2,445+40.0%Added
Apriem Advisors8,584$6.63M0.61%−64−0.7%Reduced
UniSuper Management Pty Ltd8,639$6.67M0.04%−920−9.6%Reduced
Legato Capital Management LLC8,803$6.79M0.58%−1,400−13.7%Reduced
Renaissance Technologies LLC9,082$7.01M0.01%−266,080−96.7%Reduced
Callan Family Office, LLC9,092$7.02M0.15%+2,348+34.8%Added
Investment Management Corp of Ontario9,206$7.11M0.09%+2,050+28.6%Added
Yousif Capital Management, LLC9,706$7.12M0.08%−585−5.7%Reduced
Kayne Anderson Rudnick Investment Management LLC9,356$7.22M0.02%+69+0.7%Added
Leuthold Group, LLC9,439$7.29M0.79%+3,395+56.2%Added
Verition Fund Management LLC9,491$7.33M0.04%−6,933−42.2%Reduced
Engineers Gate Manager LP9,607$7.42M0.09%−9,467−49.6%Reduced
Voleon Capital Management LP9,610$7.42M0.16%−16,108−62.6%Reduced
Norinchukin Bank, The9,632$7.43M0.09%+821+9.3%Added
AIMZ Investment Advisors, LLC9,649$7.45M2.13%−80−0.8%Reduced
Schroder Investment Management Group9,711$7.50M0.01%−16,044−62.3%Reduced
Martingale Asset Management L P9,764$7.54M0.19%+9,764New
Evergreen Wealth Management, LLC9,823$7.58M3.82%+195+2.0%Added
Summit Global Investments9,822$7.58M0.45%−9,801−49.9%Reduced
CIBC World Markets Inc.9,862$7.61M0.01%−5,871−37.3%Reduced
GWM Advisors LLC9,920$7.66M0.03%+5,888+146.0%Added
DCF Advisers, LLC10,000$7.72M2.55%00.0%Unchanged
Beacon Investment Advisory Services, Inc.10,075$7.78M0.32%−1,450−12.6%Reduced
Eversept Partners, LP10,097$7.79M0.44%−6,623−39.6%Reduced
Rock Springs Capital Management LP10,100$7.80M0.40%−1,200−10.6%Reduced
Harvey Capital Management Inc10,198$7.87M1.68%−1,204−10.6%Reduced
Diadema Partners LP10,300$7.95M4.73%−19,860−65.8%Reduced
Jacobs & Co10,326$7.97M0.75%+164+1.6%Added
O'Shaughnessy Asset Management, LLC10,495$8.10M0.04%+3,506+50.2%Added
Oak Associates, Ltd10,560$8.15M0.49%+70+0.7%Added
Clear Harbor Asset Management, LLC10,564$8.15M0.56%−73−0.7%Reduced
Biondo Investment Advisors, LLC10,673$8.24M1.00%+2,409+29.2%Added
Swiss Life Asset Management Ltd10,762$8.31M0.04%−12,896−54.5%Reduced
Mutual of America Capital Management LLC10,803$8.34M0.09%−221−2.0%Reduced
Lazard Asset Management LLC10,838$8.37M0.01%+458+4.4%Added
Hunter Perkins Capital Management, LLC10,887$8.40M1.94%−729−6.3%Reduced
Massmutual Trust Co FSB11,103$8.57M0.22%+994+9.8%Added
Lido Advisors, LLC13,417$8.67M0.03%+1,271+10.5%Added
Janney Montgomery Scott LLC11,233$8.67M0.02%−4,533−28.8%Reduced
Assetmark, Inc11,280$8.71M0.02%−9,539−45.8%Reduced
Atria Investments LLC11,432$8.82M0.10%−45−0.4%Reduced
Pinebridge Investments LLC11,455$8.84M0.07%+11,455New
Fideuram Asset Management (Ireland) dac13,111$8.86M0.71%+13,111New
Greenwood Capital Associates LLC11,528$8.90M0.97%−1,063−8.4%Reduced
Slow Capital, Inc.11,536$8.90M1.06%−1,002−8.0%Reduced
Oregon Public Employees Retirement Fund11,558$8.92M0.11%−109−0.9%Reduced
Ci Investments Inc.11,593$8.95M0.04%+6,999+152.4%Added
Vestor Capital, LLC2,001$9.01M0.66%+2,001New
OP Asset Management Ltd11,715$9.04M0.11%+59+0.5%Added
Calamos Advisors LLC11,793$9.10M0.04%−479−3.9%Reduced
Advisor Group Holdings, Inc.11,799$9.11M0.01%−2,937−19.9%Reduced
Banque Pictet & Cie SA11,822$9.13M0.09%+1,234+11.7%Added
Colony Group, LLC11,906$9.19M0.01%+2,754+30.1%Added
Thompson Siegel & Walmsley LLC11,907$9.19M0.15%−175−1.4%Reduced
JustInvest LLC11,973$9.24M0.09%+901+8.1%Added
Louisiana State Employees Retirement System12,000$9.26M0.16%−900−7.0%Reduced
Sterling Capital Management LLC12,035$9.29M0.15%+8,441+234.9%Added
ADAR1 Capital Management, LLC12,051$9.30M0.70%−3,649−23.2%Reduced
Beacon Pointe Advisors, LLC12,064$9.31M0.07%−147−1.2%Reduced
Marietta Wealth Management, LLC12,160$9.39M1.09%+135+1.1%Added
Avanza Fonder AB12,187$9.41M0.24%+1,590+15.0%Added
Anchor Capital Advisors LLC12,499$9.65M0.28%+702+6.0%Added
Capital International Inc12,503$9.65M0.08%−24,867−66.5%Reduced
Jane Street Group, LLC12,621$9.74M0.01%−84,089−86.9%Reduced
NorthCrest Asset Manangement, LLC12,782$9.76M0.22%+886+7.4%Added
Profund Advisors LLC12,660$9.77M0.30%+825+7.0%Added
RK Asset Management, LLC12,660$9.77M9.22%+14+0.1%Added
Vega Investment Solutions12,688$9.79M1.56%+12,688New
Public Sector Pension Investment Board12,752$9.84M0.03%+4,373+52.2%Added
Prime Capital Investment Advisors, LLC12,783$9.87M0.12%+309+2.5%Added
Summit Financial, LLC12,784$9.87M0.14%+42+0.3%Added
Walleye Trading LLC12,872$9.94M0.16%+7,374+134.1%Added
Elo Mutual Pension Insurance Co12,961$10.0M0.15%−470−3.5%Reduced
South Dakota Investment Council12,962$10.0M0.19%+160+1.2%Added
PBU - The Pension Fund of Early Childhood & Youth Educators13,213$10.2M0.15%+13,213New
Public Employees Retirement Association of Colorado13,423$10.4M0.04%−101−0.7%Reduced
Vontobel Holding Ltd.13,543$10.5M0.03%+3,180+30.7%Added
Eurizon Capital SGR S.p.A.13,565$10.5M0.03%+13,565New
Capital International Ltd13,610$10.5M0.37%−14,302−51.2%Reduced
Vinva Investment Management Ltd13,890$10.8M0.13%+5,115+58.3%Added
Bellevue Group AG13,928$10.8M0.20%−1,129−7.5%Reduced
Fagan Associates, Inc.13,931$10.8M1.43%−47−0.3%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd14,057$10.9M0.09%−184−1.3%Reduced
Ossiam14,690$11.3M0.23%+1,666+12.8%Added
Charter Trust Co14,696$11.3M0.66%+2,416+19.7%Added
M. Kulyk & Associates, LLC14,804$11.4M2.18%+431+3.0%Added
Ensign Peak Advisors, Inc14,849$11.5M0.02%−16,314−52.4%Reduced
Ilmarinen Mutual Pension Insurance Co14,900$11.5M0.09%00.0%Unchanged
Pathstone Holdings, LLC14,924$11.5M0.04%+2,284+18.1%Added
New York Life Investment Management LLC15,087$11.6M0.10%+1,144+8.2%Added
Mercer Global Advisors Inc15,136$11.7M0.02%+2,796+22.7%Added
Toroso Investments, LLC15,401$11.9M0.05%−176−1.1%Reduced
Fifth Third Bancorp15,425$11.9M0.04%+3,362+27.9%Added
Police & Firemen's Retirement System of New Jersey15,570$12.0M0.10%−1,221−7.3%Reduced
Picton Mahoney Asset Management15,584$12.0M0.13%+7,349+89.2%Added