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Regeneron Pharmaceuticals, Inc.

REGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000872589

In the last 90 days, Regeneron Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 5 sales; 1,341 institutions reported holding it in 13F filings for Q2 2026, worth $57.1B in total; Southeastern Asset Management (Longleaf) is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Regeneron Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,387
+167 vs. Q3 2025
Shares held
91.6M
+4.76M (+5.5%) vs. Q3 2025
Total value
$70.7B
+$21.9B (+44.9%) vs. Q3 2025
New holders
273
502 more added
Sold out
106
457 more reduced

23 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting REGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 1,387 institutions
Q1 2021: 926 institutionsQ2 2021: 975 institutionsQ3 2021: 1,022 institutionsQ4 2021: 1,081 institutionsQ1 2022: 1,097 institutionsQ2 2022: 1,066 institutionsQ3 2022: 1,081 institutionsQ4 2022: 1,161 institutionsQ1 2023: 1,196 institutionsQ2 2023: 1,168 institutionsQ3 2023: 1,180 institutionsQ4 2023: 1,274 institutionsQ1 2024: 1,313 institutionsQ2 2024: 1,335 institutionsQ3 2024: 1,393 institutionsQ4 2024: 1,320 institutionsQ1 2025: 1,290 institutionsQ2 2025: 1,201 institutionsQ3 2025: 1,243 institutionsQ4 2025: 1,387 institutionsQ1 2026: 1,401 institutionsQ2 2026: 1,341 institutions
Value heldQ4 2025: $70.7B
Q1 2021: $42.3BQ2 2021: $49.6BQ3 2021: $54.5BQ4 2021: $56.9BQ1 2022: $64.5BQ2 2022: $55.0BQ3 2022: $64.0BQ4 2022: $66.9BQ1 2023: $76.1BQ2 2023: $66.2BQ3 2023: $75.1BQ4 2023: $80.3BQ1 2024: $89.3BQ2 2024: $98.9BQ3 2024: $97.5BQ4 2024: $66.6BQ1 2025: $59.0BQ2 2025: $46.9BQ3 2025: $49.0BQ4 2025: $70.7BQ1 2026: $69.8BQ2 2026: $57.1B
Institutions holding REGN and their total value by quarter
QuarterHoldersValue
Q2 20261,341$57.1B
Q1 20261,401$69.8B
Q4 20251,387$70.7B
Q3 20251,243$49.0B
Q2 20251,201$46.9B
Q1 20251,290$59.0B
Q4 20241,320$66.6B
Q3 20241,393$97.5B
Q2 20241,335$98.9B
Q1 20241,313$89.3B
Q4 20231,274$80.3B
Q3 20231,180$75.1B
Q2 20231,168$66.2B
Q1 20231,196$76.1B
Q4 20221,161$66.9B
Q3 20221,081$64.0B
Q2 20221,066$55.0B
Q1 20221,097$64.5B
Q4 20211,081$56.9B
Q3 20211,022$54.5B
Q2 2021975$49.6B
Q1 2021926$42.3B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Regeneron Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding REGN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc9,075,153$7.00B0.10%+26,884+0.3%Added
BlackRock, Inc.8,741,270$6.75B0.11%−95,904−1.1%Reduced
State Street Corp4,660,808$3.60B0.12%−30,415−0.6%Reduced
Dodge & Cox4,596,358$3.55B1.92%+45,513+1.0%Added
JPMorgan Chase & Co3,940,160$3.04B0.20%−132,166−3.2%Reduced
Invesco Ltd.3,911,496$3.02B0.28%+2,427,023+163.5%Added
Franklin Resources Inc2,560,004$1.98B0.49%+106,861+4.4%Added
Geode Capital Management, LLC2,519,540$1.94B0.12%−16,358−0.6%Reduced
FMR LLC2,319,566$1.79B0.09%+383,731+19.8%Added
Nuveen, LLC2,010,517$1.55B0.41%+835,240+71.1%Added
Price T Rowe Associates Inc1,949,797$1.50B0.16%+1,144,887+142.2%Added
Loomis Sayles & Co L P1,934,326$1.49B1.80%−45,127−2.3%Reduced
Capital World Investors1,398,003$1.08B0.15%−600,363−30.0%Reduced
Morgan Stanley1,389,323$1.07B0.06%−61,649−4.2%Reduced
Norges Bank1,311,485$1.01B0.11%+1,311,485New
Bank of America Corp1,157,426$893.4M0.06%+3,493+0.3%Added
Goldman Sachs Group Inc1,097,327$847.0M0.12%+144,488+15.2%Added
AQR Capital Management LLC995,710$768.5M0.40%+274,356+38.0%Added
Northern Trust Corp944,933$729.4M0.09%−39,859−4.0%Reduced
Amundi791,906$611.2M0.17%+170,165+27.4%Added
Charles Schwab Investment Management Inc778,001$600.5M0.09%+22,436+3.0%Added
Bank of New York Mellon Corp764,242$589.9M0.10%+92,612+13.8%Added
Deutsche Bank AG763,926$589.7M0.19%+67,245+9.7%Added
UBS Asset Management Americas Inc745,233$575.2M0.12%+1,060+0.1%Added
Legal & General Group Plc743,027$573.5M0.13%−27,332−3.5%Reduced
Wellington Management Group LLP664,465$512.9M0.09%+656,845+8,620.0%Added
Two Sigma Advisers, LP604,540$466.6M0.91%−321,660−34.7%Reduced
American Century Companies Inc551,487$425.7M0.21%−109,108−16.5%Reduced
FIL Ltd529,190$408.5M0.31%+341,666+182.2%Added
Dimensional Fund Advisors LP499,544$385.6M0.08%+448+0.1%Added
Marshall Wace, LLP478,551$369.4M0.36%+91,667+23.7%Added
Alliancebernstein L.P.478,389$369.3M0.12%−45,494−8.7%Reduced
Holocene Advisors, LP460,723$355.6M0.75%+308,990+203.6%Added
Acadian Asset Management LLC445,795$344.0M0.56%−138,710−23.7%Reduced
BNP Paribas Arbitrage, SA440,844$340.3M0.22%−36,808−7.7%Reduced
Neuberger Berman Group LLC422,127$325.8M0.24%+6,413+1.5%Added
Manufacturers Life Insurance Company, The421,229$325.3M0.27%+40,214+10.6%Added
Pacer Advisors, Inc.397,666$306.9M0.80%−47,659−10.7%Reduced
TD Asset Management Inc397,552$306.9M0.25%+23,288+6.2%Added
Millennium Management LLC379,768$293.1M0.21%+178,688+88.9%Added
Pictet Asset Management Holding SA367,870$284.7M0.28%+44,500+13.8%Added
National Pension Service360,988$278.6M0.21%+82,853+29.8%Added
Royal Bank of Canada345,219$266.5M0.05%−27,876−7.5%Reduced
Caisse de Depot Et Placement du Quebec342,319$264.2M0.45%−120,183−26.0%Reduced
HSBC Holdings PLC318,808$246.2M0.14%−51,157−13.8%Reduced
Barclays PLC311,167$240.2M0.10%−14,754−4.5%Reduced
Voya Investment Management LLC294,049$226.8M0.22%+166,513+130.6%Added
Ameriprise Financial Inc291,919$225.6M0.05%+8,814+3.1%Added
Swiss National Bank285,460$220.3M0.13%−20,540−6.7%Reduced
Sumitomo Mitsui Trust Holdings, Inc.285,031$220.0M0.13%−22,258−7.2%Reduced
Epoch Investment Partners, Inc.281,335$217.2M1.23%+22,182+8.6%Added
Two Sigma Investments, LP281,151$217.0M0.32%−188,752−40.2%Reduced
UBS Group AG271,158$209.3M0.04%−68,331−20.1%Reduced
DekaBank Deutsche Girozentrale211,207$206.8M0.39%00.0%Unchanged
Jacobs Levy Equity Management, Inc264,991$204.5M0.79%−22,890−8.0%Reduced
Point72 Asset Management, L.P.262,527$202.6M0.32%+61,028+30.3%Added
Robeco Institutional Asset Management B.V.261,850$202.1M0.29%+140,966+116.6%Added
Federated Hermes, Inc.246,619$190.4M0.32%+10,419+4.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.246,476$190.3M0.22%+11,644+5.0%Added
Citigroup Inc245,335$189.4M0.13%+107,144+77.5%Added
Assenagon Asset Management S.A.233,231$180.0M0.27%−244,579−51.2%Reduced
Swedbank AB227,779$175.8M0.17%+20,409+9.8%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.224,857$174.6M0.12%+8,688+4.0%Added
Russell Investments Group, Ltd.221,090$170.7M0.19%−7,738−3.4%Reduced
Man Group plc218,112$168.4M0.32%−53,595−19.7%Reduced
1832 Asset Management L.P.216,864$167.4M0.21%+216,864New
McDonald Capital Investors Inc208,241$160.7M9.86%−5,090−2.4%Reduced
First Trust Advisors LP205,732$158.8M0.12%+7,475+3.8%Added
Janus Henderson Group PLC205,672$158.8M0.07%+131,929+178.9%Added
Candriam Luxembourg S.C.A.205,332$158.5M0.79%+35,837+21.1%Added
Polar Capital Holdings Plc204,927$158.2M0.72%+46,110+29.0%Added
California Public Employees Retirement System201,090$155.2M0.09%−2,024−1.0%Reduced
Chevy Chase Trust Holdings, Inc.200,747$155.0M0.42%−2,405−1.2%Reduced
Arrowstreet Capital, Limited Partnership194,695$150.3M0.09%+2,111+1.1%Added
ProShare Advisors LLC184,286$142.2M0.25%+49,132+36.4%Added
Bronte Capital Management Pty Ltd.176,768$136.4M14.26%−3,515−1.9%Reduced
Sound Shore Management Inc175,887$135.8M4.32%+60,859+52.9%Added
Allianz Asset Management GmbH168,614$130.1M0.15%+152,202+927.4%Added
Canada Pension Plan Investment Board168,367$130.0M0.09%+9,545+6.0%Added
LSV Asset Management166,514$128.5M0.28%+110,914+199.5%Added
Southeastern Asset Management IncSuperinvestorSoutheastern Asset Management (Longleaf)165,792$128.0M5.70%+21,185+14.7%Added
Standard Life Aberdeen plc161,738$124.8M0.19%+10,235+6.8%Added
Rhumbline Advisers160,805$124.1M0.10%−7,196−4.3%Reduced
California State Teachers Retirement System158,680$122.5M0.12%−4,155−2.6%Reduced
D. E. Shaw & Co., Inc.155,475$120.0M0.09%−706,118−82.0%Reduced
Raymond James Financial Inc149,610$115.5M0.04%+11,104+8.0%Added
Citadel Advisors LLC144,970$111.9M0.08%−85,257−37.0%Reduced
Qube Research & Technologies Ltd142,183$109.7M0.16%−406,551−74.1%Reduced
Wells Fargo & Company140,049$108.1M0.02%+5,829+4.3%Added
Nordea Investment Management AB137,321$105.8M0.09%+74,350+118.1%Added
SG Americas Securities, LLC131,112$101.2M0.13%+118,690+955.5%Added
Retirement Systems of Alabama128,317$99.0M0.32%−292−0.2%Reduced
Natixis Advisors, L.P.122,588$94.6M0.13%+2,479+2.1%Added
Bank of Nova Scotia120,011$92.6M0.14%−158,540−56.9%Reduced
National Bank of Canada119,812$92.5M0.09%−44,573−27.1%Reduced
Principal Financial Group Inc119,625$92.3M0.05%+1,142+1.0%Added
New York State Common Retirement Fund117,369$90.6M0.12%−3,200−2.7%Reduced
Healthcare of Ontario Pension Plan Trust Fund114,713$88.5M0.15%−183−0.2%Reduced
Victory Capital Management Inc111,964$86.4M0.05%+29,578+35.9%Added
Universal- Beteiligungs- und Servicegesellschaft mbH108,871$84.2M0.14%+827+0.8%Added