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Arcus Biosciences, Inc.

RCUS
Exchange
NYSE
Industry
Pharmaceutical Preparations
SEC CIK
0001724521

In the last 90 days, Arcus Biosciences, Inc. insiders filed 0 open-market purchases and 2 sales; 231 institutions reported holding it in 13F filings for Q2 2026, worth $3.78B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Arcus Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
209
+21 vs. Q3 2025
Shares held
121.4M
+21.0M (+21.0%) vs. Q3 2025
Total value
$2.89B
+$1.53B (+112.0%) vs. Q3 2025
New holders
48
95 more added
Sold out
27
38 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RCUS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 209 institutions
Q1 2021: 148 institutionsQ2 2021: 130 institutionsQ3 2021: 131 institutionsQ4 2021: 142 institutionsQ1 2022: 157 institutionsQ2 2022: 173 institutionsQ3 2022: 183 institutionsQ4 2022: 200 institutionsQ1 2023: 180 institutionsQ2 2023: 181 institutionsQ3 2023: 187 institutionsQ4 2023: 185 institutionsQ1 2024: 172 institutionsQ2 2024: 193 institutionsQ3 2024: 187 institutionsQ4 2024: 186 institutionsQ1 2025: 187 institutionsQ2 2025: 186 institutionsQ3 2025: 190 institutionsQ4 2025: 209 institutionsQ1 2026: 211 institutionsQ2 2026: 231 institutions
Value heldQ4 2025: $2.89B
Q1 2021: $1.25BQ2 2021: $1.24BQ3 2021: $1.68BQ4 2021: $2.06BQ1 2022: $1.60BQ2 2022: $1.33BQ3 2022: $1.37BQ4 2022: $1.11BQ1 2023: $1.01BQ2 2023: $1.11BQ3 2023: $947.9MQ4 2023: $1.01BQ1 2024: $997.7MQ2 2024: $790.9MQ3 2024: $815.7MQ4 2024: $1.25BQ1 2025: $763.3MQ2 2025: $811.5MQ3 2025: $1.37BQ4 2025: $2.89BQ1 2026: $2.57BQ2 2026: $3.78B
Institutions holding RCUS and their total value by quarter
QuarterHoldersValue
Q2 2026231$3.78B
Q1 2026211$2.57B
Q4 2025209$2.89B
Q3 2025190$1.37B
Q2 2025186$811.5M
Q1 2025187$763.3M
Q4 2024186$1.25B
Q3 2024187$815.7M
Q2 2024193$790.9M
Q1 2024172$997.7M
Q4 2023185$1.01B
Q3 2023187$947.9M
Q2 2023181$1.11B
Q1 2023180$1.01B
Q4 2022200$1.11B
Q3 2022183$1.37B
Q2 2022173$1.33B
Q1 2022157$1.60B
Q4 2021142$2.06B
Q3 2021131$1.68B
Q2 2021130$1.24B
Q1 2021148$1.25B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Arcus Biosciences, Inc.; share changes are against Q3 2025.

Institutions holding RCUS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.31,424,760$748.9M38.69%00.0%Unchanged
BlackRock, Inc.14,997,891$357.4M0.01%+3,187,025+27.0%Added
Vanguard Group Inc7,962,874$189.8M0.00%+1,333,421+20.1%Added
Suvretta Capital Management, LLC5,188,858$123.7M3.08%+1,500,000+40.7%Added
Wellington Management Group LLP5,184,509$123.5M0.02%+3,918,220+309.4%Added
State Street Corp4,576,969$109.1M0.00%+1,182,115+34.8%Added
Woodline Partners LP3,769,788$89.8M0.35%+1040.0%Added
Marshall Wace, LLP3,387,794$80.7M0.08%+3,387,794New
Point72 Asset Management, L.P.3,280,000$78.2M0.12%−1,052,479−24.3%Reduced
Siren, L.L.C.3,007,077$71.7M2.14%+95,000+3.3%Added
Fisher Asset Management, LLC1,949,788$46.5M0.02%+1,220,635+167.4%Added
Geode Capital Management, LLC1,907,345$45.5M0.00%+308,936+19.3%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,687,374$40.2M0.05%+267,389+18.8%Added
Samlyn Capital, LLC1,604,270$38.2M0.61%+1,604,270New
Dimensional Fund Advisors LP1,524,157$36.3M0.01%+21,694+1.4%Added
Toronto Dominion Bank1,484,699$35.4M0.06%+1,484,699New
Morgan Stanley1,210,754$28.9M0.00%−325,334−21.2%Reduced
Goldman Sachs Group Inc1,168,437$27.8M0.00%+217,848+22.9%Added
FMR LLC1,135,178$27.1M0.00%−1,160,843−50.6%Reduced
Barclays PLC1,112,258$26.5M0.01%+935,178+528.1%Added
Sofinnova Investments, Inc.1,096,705$26.1M1.13%−125,558−10.3%Reduced
Bank of America Corp1,000,818$23.8M0.00%−359,963−26.5%Reduced
Parkman Healthcare Partners LLC968,602$23.1M2.20%+315,922+48.4%Added
Charles Schwab Investment Management Inc968,241$23.1M0.00%+97,091+11.1%Added
Jacobs Levy Equity Management, Inc929,981$22.2M0.09%−190,081−17.0%Reduced
Trails Edge Capital Partners, LP916,313$21.8M5.40%+916,313New
Franklin Resources Inc853,491$20.3M0.00%+853,491New
Balyasny Asset Management LLC815,561$19.4M0.04%+715,188+712.5%Added
Northern Trust Corp794,798$18.9M0.00%+87,002+12.3%Added
Candriam Luxembourg S.C.A.790,613$18.8M0.09%+412,172+108.9%Added
Caption Management, LLC767,698$18.3M0.81%+767,698New
Soleus Capital Management, L.P.711,983$17.0M0.72%+711,983New
First Turn Management, LLC565,142$13.5M1.54%+565,142New
Decheng Capital LLC541,559$12.9M1.74%−6,050−1.1%Reduced
Bank of New York Mellon Corp504,462$12.0M0.00%+34,252+7.3%Added
DAFNA Capital Management LLC431,329$10.3M2.39%−196,297−31.3%Reduced
BNP Paribas Arbitrage, SA424,071$10.1M0.01%+340,048+404.7%Added
Invesco Ltd.414,365$9.87M0.00%+121,961+41.7%Added
UBS Group AG411,259$9.80M0.00%+243,855+145.7%Added
Principal Financial Group Inc407,513$9.71M0.00%+72,989+21.8%Added
PDT Partners, LLC388,338$9.25M0.60%00.0%Unchanged
Standard Life Aberdeen plc384,601$9.17M0.01%+52,930+16.0%Added
Nomura Asset Management International Inc.379,100$9.03M0.01%+379,100New
Susquehanna International Group, LLP341,865$8.15M0.01%−47,276−12.1%Reduced
Affinity Asset Advisors, LLC300,000$7.15M0.51%+300,000New
Public Sector Pension Investment Board295,426$7.04M0.02%+25,563+9.5%Added
Baker Bros. Advisors LP270,000$6.43M0.04%+270,000New
Hudson Bay Capital Management LP240,000$5.72M0.03%−100,000−29.4%Reduced
Susquehanna Portfolio Strategies, LLC239,966$5.72M0.09%00.0%Unchanged
Rhumbline Advisers227,146$5.41M0.00%+17,510+8.4%Added
Ameriprise Financial Inc225,913$5.38M0.00%+16,056+7.7%Added
Tudor Investment Corp Et Al208,639$4.97M0.03%+208,639New
Legal & General Group Plc205,203$4.89M0.00%+26,806+15.0%Added
Nicholas Investment Partners, LP204,338$4.87M0.35%+204,338New
Connor, Clark & Lunn Investment Management Ltd.203,268$4.84M0.01%+117,210+136.2%Added
Rock Springs Capital Management LP180,000$4.29M0.22%+180,000New
Patient Square Capital LP170,000$4.05M0.87%+170,000New
Granahan Investment Management Inc169,940$4.05M0.17%−285,656−62.7%Reduced
Millennium Management LLC168,876$4.02M0.00%−466,068−73.4%Reduced
Swiss National Bank167,996$4.00M0.00%+34,500+25.8%Added
UBS Asset Management Americas Inc144,093$3.43M0.00%+56,322+64.2%Added
Alyeska Investment Group, L.P.142,518$3.40M0.01%+142,518New
Nuveen, LLC141,600$3.37M0.00%+14,762+11.6%Added
Two Sigma Investments, LP139,631$3.33M0.00%−331,891−70.4%Reduced
Russell Investments Group, Ltd.136,121$3.24M0.00%+53,892+65.5%Added
Platinum Investment Management Ltd134,217$3.20M0.74%−19,566−12.7%Reduced
Alliancebernstein L.P.133,098$3.17M0.00%−4,091−3.0%Reduced
American Century Companies Inc128,947$3.07M0.00%+3,378+2.7%Added
Knott David M Jr121,241$2.89M1.34%+26,041+27.4%Added
Citadel Advisors LLC104,701$2.50M0.00%−190,353−64.5%Reduced
LMR Partners LLP100,000$2.38M0.02%+100,000New
Wells Fargo & Company99,318$2.37M0.00%+31,002+45.4%Added
Schonfeld Strategic Advisors LLC97,283$2.32M0.01%+48,389+99.0%Added
Rafferty Asset Management, LLC92,929$2.21M0.01%+23,280+33.4%Added
New York State Teachers Retirement System92,431$2.20M0.00%+1,000+1.1%Added
California State Teachers Retirement System90,666$2.16M0.00%+26,664+41.7%Added
Parallel Advisors, LLC86,557$2.06M0.04%−1,450−1.6%Reduced
AQR Capital Management LLC86,207$2.05M0.00%+2,430+2.9%Added
D. E. Shaw & Co., Inc.85,570$2.04M0.00%+65,699+330.6%Added
Thrivent Financial for Lutherans80,393$1.92M0.00%+30,484+61.1%Added
Prudential Financial Inc79,458$1.89M0.00%+9,193+13.1%Added
Great West Life Assurance Co73,862$1.76M0.00%+14,610+24.7%Added
JPMorgan Chase & Co72,755$1.73M0.00%+8,813+13.8%Added
Deutsche Bank AG62,652$1.49M0.00%+14,316+29.6%Added
Winton Group Ltd62,251$1.48M0.05%−29,978−32.5%Reduced
Dark Forest Capital Management LP60,614$1.44M0.07%−79,407−56.7%Reduced
State of Wisconsin Investment Board58,835$1.40M0.00%+28,117+91.5%Added
Price T Rowe Associates Inc58,649$1.40M0.00%+9,307+18.9%Added
Sectoral Asset Management Inc56,945$1.36M1.09%−311,125−84.5%Reduced
Fort Baker Capital Management LP52,523$1.25M0.14%+52,523New
Burkehill Global Management, LP50,000$1.19M0.08%+50,000New
Jane Street Group, LLC46,505$1.11M0.00%−179,127−79.4%Reduced
SG Americas Securities, LLC45,488$1.08M0.00%+12,714+38.8%Added
Fred Alger Management, LLC44,758$1.07M0.00%+44,758New
MetLife Investment Management43,434$1.04M0.01%+1,972+4.8%Added
State of Alaska, Department of Revenue43,451$1.03M0.01%+8,642+24.8%Added
New York State Common Retirement Fund43,002$1.02M0.00%+21,148+96.8%Added
Janus Henderson Group PLC42,338$1.01M0.00%+11,300+36.4%Added
Manufacturers Life Insurance Company, The41,993$1.00M0.00%+6,963+19.9%Added
Mirae Asset Global ETFs Holdings Ltd.41,955$996.5K0.00%+6,590+18.6%Added