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PTC Therapeutics, Inc.

PTCT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001070081

In the last 90 days, PTC Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 382 institutions reported holding it in 13F filings for Q2 2026, worth $8.20B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in PTC Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
353
+64 vs. Q3 2025
Shares held
92.7M
+10.1M (+12.3%) vs. Q3 2025
Total value
$7.04B
+$1.97B (+39.0%) vs. Q3 2025
New holders
101
126 more added
Sold out
37
96 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTCT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 353 institutions
Q1 2021: 208 institutionsQ2 2021: 183 institutionsQ3 2021: 184 institutionsQ4 2021: 179 institutionsQ1 2022: 184 institutionsQ2 2022: 182 institutionsQ3 2022: 213 institutionsQ4 2022: 203 institutionsQ1 2023: 203 institutionsQ2 2023: 206 institutionsQ3 2023: 181 institutionsQ4 2023: 174 institutionsQ1 2024: 184 institutionsQ2 2024: 199 institutionsQ3 2024: 203 institutionsQ4 2024: 240 institutionsQ1 2025: 261 institutionsQ2 2025: 284 institutionsQ3 2025: 294 institutionsQ4 2025: 353 institutionsQ1 2026: 352 institutionsQ2 2026: 382 institutions
Value heldQ4 2025: $7.04B
Q1 2021: $3.52BQ2 2021: $3.13BQ3 2021: $2.77BQ4 2021: $3.00BQ1 2022: $2.76BQ2 2022: $2.97BQ3 2022: $3.83BQ4 2022: $2.94BQ1 2023: $3.81BQ2 2023: $3.30BQ3 2023: $1.83BQ4 2023: $2.33BQ1 2024: $2.48BQ2 2024: $2.44BQ3 2024: $2.93BQ4 2024: $3.51BQ1 2025: $4.02BQ2 2025: $3.90BQ3 2025: $5.07BQ4 2025: $7.04BQ1 2026: $6.51BQ2 2026: $8.20B
Institutions holding PTCT and their total value by quarter
QuarterHoldersValue
Q2 2026382$8.20B
Q1 2026352$6.51B
Q4 2025353$7.04B
Q3 2025294$5.07B
Q2 2025284$3.90B
Q1 2025261$4.02B
Q4 2024240$3.51B
Q3 2024203$2.93B
Q2 2024199$2.44B
Q1 2024184$2.48B
Q4 2023174$2.33B
Q3 2023181$1.83B
Q2 2023206$3.30B
Q1 2023203$3.81B
Q4 2022203$2.94B
Q3 2022213$3.83B
Q2 2022182$2.97B
Q1 2022184$2.76B
Q4 2021179$3.00B
Q3 2021184$2.77B
Q2 2021183$3.13B
Q1 2021208$3.52B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding PTC Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding PTCT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Russell Investments Group, Ltd.270,748$20.6M0.02%+23,255+9.4%Added
Ensign Peak Advisors, Inc280,572$21.3M0.04%−8,195−2.8%Reduced
Public Sector Pension Investment Board324,636$24.7M0.08%+324,636New
Voya Investment Management LLC339,146$25.8M0.03%+54,255+19.0%Added
AQR Capital Management LLC341,927$26.0M0.01%+10,671+3.2%Added
JPMorgan Chase & Co356,041$27.0M0.00%−134,893−27.5%Reduced
Panagora Asset Management Inc359,837$27.3M0.10%+11,471+3.3%Added
Jupiter Asset Management Ltd361,159$27.4M0.22%+361,159New
Legal & General Group Plc366,265$27.8M0.01%+124,923+51.8%Added
Rockefeller Capital Management L.P.405,536$30.8M0.06%−68,222−14.4%Reduced
Arrowstreet Capital, Limited Partnership406,410$30.9M0.02%+82,862+25.6%Added
Manufacturers Life Insurance Company, The426,506$32.4M0.03%+1,507+0.4%Added
MPM Oncology Impact Management LP430,013$32.7M3.74%−8,464−1.9%Reduced
Invesco Ltd.434,285$33.0M0.00%+121,228+38.7%Added
Price T Rowe Associates Inc460,114$35.0M0.00%+1,784+0.4%Added
Principal Financial Group Inc478,897$36.4M0.02%+411,220+607.6%Added
Boston Partners487,977$37.1M0.04%+126,313+34.9%Added
Bank of New York Mellon Corp514,680$39.1M0.01%+241,604+88.5%Added
Woodline Partners LP571,553$43.4M0.17%+465,948+441.2%Added
Renaissance Technologies LLC607,589$46.2M0.07%−319,711−34.5%Reduced
Dimensional Fund Advisors LP627,092$47.6M0.01%−146,086−18.9%Reduced
Lord, Abbett & Co. LLC627,106$47.6M0.15%+249,053+65.9%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.647,585$49.2M0.06%−153,293−19.1%Reduced
Avoro Capital Advisors LLC685,000$52.0M0.51%+685,000New
Nuveen, LLC699,190$53.1M0.01%−22,012−3.1%Reduced
Charles Schwab Investment Management Inc734,933$55.8M0.01%+32,175+4.6%Added
Northern Trust Corp769,420$58.4M0.01%+31,851+4.3%Added
BNP Paribas Arbitrage, SA828,662$62.9M0.04%+808,515+4,013.1%Added
SG Americas Securities, LLC894,461$67.9M0.09%+764,364+587.5%Added
Palo Alto Investors LP903,916$68.7M9.56%+41,303+4.8%Added
Morgan Stanley905,192$68.8M0.00%+485,775+115.8%Added
UBS Group AG964,658$73.3M0.01%+512,449+113.3%Added
Pictet Asset Management Holding SA978,957$74.8M0.07%−429,017−30.5%Reduced
Hood River Capital Management LLC1,003,075$76.2M0.84%+7,293+0.7%Added
Goldman Sachs Group Inc1,023,091$77.7M0.01%+146,682+16.7%Added
Point72 Asset Management, L.P.1,128,551$85.7M0.13%−92,091−7.5%Reduced
Driehaus Capital Management LLC1,136,188$86.3M0.59%+4,439+0.4%Added
Citadel Advisors LLC1,154,455$87.7M0.06%−576,570−33.3%Reduced
Franklin Resources Inc1,286,685$97.7M0.02%+129,651+11.2%Added
Bank of America Corp1,431,557$108.7M0.01%−85,479−5.6%Reduced
Tang Capital Management LLC1,500,000$113.9M5.63%00.0%Unchanged
Jefferies Financial Group Inc.1,658,481$126.0M1.03%+73,803+4.7%Added
FMR LLC1,681,216$127.7M0.01%+69,441+4.3%Added
D. E. Shaw & Co., Inc.1,744,991$132.5M0.10%−429,617−19.8%Reduced
Geode Capital Management, LLC2,016,062$153.2M0.01%+65,184+3.3%Added
Armistice Capital, LLC2,801,869$212.8M5.21%−475,403−14.5%Reduced
Wellington Management Group LLP3,867,380$293.8M0.05%−1,051,239−21.4%Reduced
Toronto Dominion Bank4,138,215$314.3M0.55%+891,690+27.5%Added
State Street Corp4,206,126$319.5M0.01%+1,071,343+34.2%Added
Janus Henderson Group PLC4,851,332$368.6M0.17%+1,077,776+28.6%Added
RTW Investments, LP7,746,415$588.4M5.89%00.0%Unchanged
Vanguard Group Inc8,803,203$668.7M0.01%+514,204+6.2%Added
BlackRock, Inc.12,779,065$970.7M0.02%+5,648,258+79.2%Added
Qube Research & Technologies Ltd0$00.00%−430,934−100.0%Sold out
Sofinnova Investments, Inc.0$00.00%−186,932−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−159,596−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−146,265−100.0%Sold out
Group One Trading, L.P.0$00.00%−113,271−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−102,734−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−95,925−100.0%Sold out
Cinctive Capital Management LP0$00.00%−95,308−100.0%Sold out
Alps Advisors Inc0$00.00%−36,873−100.0%Sold out
Wolverine Asset Management LLC0$00.00%−24,392−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−23,173−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−21,889−100.0%Sold out
Brummer Multi-Strategy AB0$00.00%−19,142−100.0%Sold out
Neo Ivy Capital Management0$00.00%−18,880−100.0%Sold out
State of Wyoming0$00.00%−10,870−100.0%Sold out
J. Goldman & Co LP0$00.00%−7,816−100.0%Sold out
Vontobel Holding Ltd.0$00.00%−7,620−100.0%Sold out
XTX Topco Ltd0$00.00%−7,410−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−7,384−100.0%Sold out
Steel Peak Wealth Management LLC0$00.00%−7,026−100.0%Sold out
Marex Group plc0$00.00%−3,692−100.0%Sold out
Advantage Alpha Capital Partners LP0$00.00%−3,595−100.0%Sold out
Buckingham Strategic Partners0$00.00%−3,033−100.0%Sold out
Envestnet Portfolio Solutions, Inc.0$00.00%−3,454−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−3,347−100.0%Sold out
Plato Investment Management Ltd0$00.00%−917−100.0%Sold out
Principal Securities, Inc.0$00.00%−814−100.0%Sold out
Optiver Holding B.V.0$00.00%−507−100.0%Sold out
Manchester Capital Management LLC0$00.00%−230−100.0%Sold out
Rise Advisors, LLC0$00.00%−184−100.0%Sold out
Advisory Services Network, LLC0$00.00%−50−100.0%Sold out
WPG Advisers, LLC0$00.00%−16−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−14−100.0%Sold out
American National Bank0$00.00%−10−100.0%Sold out
Bear Mountain Capital, Inc.0$00.00%−8−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−5−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−9−100.0%Sold out
Point72 Europe (London) LLP––––Not filed
AXA Investment Managers S.A.––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Shell Asset Management Co––––Not filed
Hemington Wealth Management––––Not filed