PTC Therapeutics, Inc.
PTCT- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001070081
In the last 90 days, PTC Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 382 institutions reported holding it in 13F filings for Q2 2026, worth $8.20B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in PTC Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 353
- +64 vs. Q3 2025
- Shares held
- 92.7M
- +10.1M (+12.3%) vs. Q3 2025
- Total value
- $7.04B
- +$1.97B (+39.0%) vs. Q3 2025
- New holders
- 101
- 126 more added
- Sold out
- 37
- 96 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTCT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 382 | $8.20B |
| Q1 2026 | 352 | $6.51B |
| Q4 2025 | 353 | $7.04B |
| Q3 2025 | 294 | $5.07B |
| Q2 2025 | 284 | $3.90B |
| Q1 2025 | 261 | $4.02B |
| Q4 2024 | 240 | $3.51B |
| Q3 2024 | 203 | $2.93B |
| Q2 2024 | 199 | $2.44B |
| Q1 2024 | 184 | $2.48B |
| Q4 2023 | 174 | $2.33B |
| Q3 2023 | 181 | $1.83B |
| Q2 2023 | 206 | $3.30B |
| Q1 2023 | 203 | $3.81B |
| Q4 2022 | 203 | $2.94B |
| Q3 2022 | 213 | $3.83B |
| Q2 2022 | 182 | $2.97B |
| Q1 2022 | 184 | $2.76B |
| Q4 2021 | 179 | $3.00B |
| Q3 2021 | 184 | $2.77B |
| Q2 2021 | 183 | $3.13B |
| Q1 2021 | 208 | $3.52B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding PTC Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 12,779,065 | $970.7M | 0.02% | +5,648,258+79.2% | Added |
| Vanguard Group Inc | 8,803,203 | $668.7M | 0.01% | +514,204+6.2% | Added |
| RTW Investments, LP | 7,746,415 | $588.4M | 5.89% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 4,851,332 | $368.6M | 0.17% | +1,077,776+28.6% | Added |
| State Street Corp | 4,206,126 | $319.5M | 0.01% | +1,071,343+34.2% | Added |
| Toronto Dominion Bank | 4,138,215 | $314.3M | 0.55% | +891,690+27.5% | Added |
| Wellington Management Group LLP | 3,867,380 | $293.8M | 0.05% | −1,051,239−21.4% | Reduced |
| Armistice Capital, LLC | 2,801,869 | $212.8M | 5.21% | −475,403−14.5% | Reduced |
| Geode Capital Management, LLC | 2,016,062 | $153.2M | 0.01% | +65,184+3.3% | Added |
| D. E. Shaw & Co., Inc. | 1,744,991 | $132.5M | 0.10% | −429,617−19.8% | Reduced |
| FMR LLC | 1,681,216 | $127.7M | 0.01% | +69,441+4.3% | Added |
| Jefferies Financial Group Inc. | 1,658,481 | $126.0M | 1.03% | +73,803+4.7% | Added |
| Tang Capital Management LLC | 1,500,000 | $113.9M | 5.63% | 00.0% | Unchanged |
| Bank of America Corp | 1,431,557 | $108.7M | 0.01% | −85,479−5.6% | Reduced |
| Franklin Resources Inc | 1,286,685 | $97.7M | 0.02% | +129,651+11.2% | Added |
| Citadel Advisors LLC | 1,154,455 | $87.7M | 0.06% | −576,570−33.3% | Reduced |
| Driehaus Capital Management LLC | 1,136,188 | $86.3M | 0.59% | +4,439+0.4% | Added |
| Point72 Asset Management, L.P. | 1,128,551 | $85.7M | 0.13% | −92,091−7.5% | Reduced |
| Goldman Sachs Group Inc | 1,023,091 | $77.7M | 0.01% | +146,682+16.7% | Added |
| Hood River Capital Management LLC | 1,003,075 | $76.2M | 0.84% | +7,293+0.7% | Added |
| Pictet Asset Management Holding SA | 978,957 | $74.8M | 0.07% | −429,017−30.5% | Reduced |
| UBS Group AG | 964,658 | $73.3M | 0.01% | +512,449+113.3% | Added |
| Morgan Stanley | 905,192 | $68.8M | 0.00% | +485,775+115.8% | Added |
| Palo Alto Investors LP | 903,916 | $68.7M | 9.56% | +41,303+4.8% | Added |
| SG Americas Securities, LLC | 894,461 | $67.9M | 0.09% | +764,364+587.5% | Added |
| BNP Paribas Arbitrage, SA | 828,662 | $62.9M | 0.04% | +808,515+4,013.1% | Added |
| Northern Trust Corp | 769,420 | $58.4M | 0.01% | +31,851+4.3% | Added |
| Charles Schwab Investment Management Inc | 734,933 | $55.8M | 0.01% | +32,175+4.6% | Added |
| Nuveen, LLC | 699,190 | $53.1M | 0.01% | −22,012−3.1% | Reduced |
| Avoro Capital Advisors LLC | 685,000 | $52.0M | 0.51% | +685,000 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 647,585 | $49.2M | 0.06% | −153,293−19.1% | Reduced |
| Lord, Abbett & Co. LLC | 627,106 | $47.6M | 0.15% | +249,053+65.9% | Added |
| Dimensional Fund Advisors LP | 627,092 | $47.6M | 0.01% | −146,086−18.9% | Reduced |
| Renaissance Technologies LLC | 607,589 | $46.2M | 0.07% | −319,711−34.5% | Reduced |
| Woodline Partners LP | 571,553 | $43.4M | 0.17% | +465,948+441.2% | Added |
| Bank of New York Mellon Corp | 514,680 | $39.1M | 0.01% | +241,604+88.5% | Added |
| Boston Partners | 487,977 | $37.1M | 0.04% | +126,313+34.9% | Added |
| Principal Financial Group Inc | 478,897 | $36.4M | 0.02% | +411,220+607.6% | Added |
| Price T Rowe Associates Inc | 460,114 | $35.0M | 0.00% | +1,784+0.4% | Added |
| Invesco Ltd. | 434,285 | $33.0M | 0.00% | +121,228+38.7% | Added |
| MPM Oncology Impact Management LP | 430,013 | $32.7M | 3.74% | −8,464−1.9% | Reduced |
| Manufacturers Life Insurance Company, The | 426,506 | $32.4M | 0.03% | +1,507+0.4% | Added |
| Arrowstreet Capital, Limited Partnership | 406,410 | $30.9M | 0.02% | +82,862+25.6% | Added |
| Rockefeller Capital Management L.P. | 405,536 | $30.8M | 0.06% | −68,222−14.4% | Reduced |
| Legal & General Group Plc | 366,265 | $27.8M | 0.01% | +124,923+51.8% | Added |
| Jupiter Asset Management Ltd | 361,159 | $27.4M | 0.22% | +361,159 | New |
| Panagora Asset Management Inc | 359,837 | $27.3M | 0.10% | +11,471+3.3% | Added |
| JPMorgan Chase & Co | 356,041 | $27.0M | 0.00% | −134,893−27.5% | Reduced |
| AQR Capital Management LLC | 341,927 | $26.0M | 0.01% | +10,671+3.2% | Added |
| Voya Investment Management LLC | 339,146 | $25.8M | 0.03% | +54,255+19.0% | Added |
| Public Sector Pension Investment Board | 324,636 | $24.7M | 0.08% | +324,636 | New |
| Ensign Peak Advisors, Inc | 280,572 | $21.3M | 0.04% | −8,195−2.8% | Reduced |
| Russell Investments Group, Ltd. | 270,748 | $20.6M | 0.02% | +23,255+9.4% | Added |
| Empowered Funds, LLC | 250,412 | $19.0M | 0.32% | +206,707+473.0% | Added |
| Marshall Wace, LLP | 247,746 | $18.8M | 0.02% | +90,007+57.1% | Added |
| Mackenzie Financial Corp | 236,909 | $18.0M | 0.02% | +35,117+17.4% | Added |
| Pacer Advisors, Inc. | 235,653 | $17.9M | 0.05% | −268,313−53.2% | Reduced |
| Deutsche Bank AG | 231,268 | $17.6M | 0.01% | +151,380+189.5% | Added |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 220,847 | $16.8M | 0.01% | −16,277−6.9% | Reduced |
| Barclays PLC | 220,196 | $16.7M | 0.01% | −19,453−8.1% | Reduced |
| Rhumbline Advisers | 207,950 | $15.8M | 0.01% | +94,046+82.6% | Added |
| Boxer Capital Management, LLC | 200,000 | $15.2M | 3.33% | 00.0% | Unchanged |
| Prudential Financial Inc | 183,185 | $13.9M | 0.02% | +95,745+109.5% | Added |
| Parkman Healthcare Partners LLC | 160,179 | $12.2M | 1.16% | −42,184−20.8% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 159,477 | $12.1M | 0.11% | +64,472+67.9% | Added |
| First Trust Advisors LP | 155,596 | $11.8M | 0.01% | +33,741+27.7% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 151,401 | $11.5M | 0.02% | +19,300+14.6% | Added |
| Ameriprise Financial Inc | 147,584 | $11.2M | 0.00% | +136,954+1,288.4% | Added |
| Swiss National Bank | 141,065 | $10.7M | 0.01% | +2,800+2.0% | Added |
| Adage Capital Partners GP, L.L.C. | 141,000 | $10.7M | 0.02% | −150,000−51.5% | Reduced |
| UBS Asset Management Americas Inc | 131,893 | $10.0M | 0.00% | +1,995+1.5% | Added |
| Ikarian Capital, LLC | 118,657 | $9.01M | 1.17% | −161,894−57.7% | Reduced |
| Federated Hermes, Inc. | 112,566 | $8.55M | 0.01% | +97,750+659.8% | Added |
| Neuberger Berman Group LLC | 111,590 | $8.48M | 0.01% | +107,983+2,993.7% | Added |
| WCM Investment Management, LLC | 110,267 | $8.40M | 0.02% | −36,798−25.0% | Reduced |
| Castleark Management LLC | 96,860 | $7.36M | 0.22% | +96,860 | New |
| Alliancebernstein L.P. | 94,308 | $7.16M | 0.00% | +2,291+2.5% | Added |
| SEI Investments Co | 92,089 | $6.99M | 0.01% | +33,748+57.8% | Added |
| Wells Fargo & Company | 86,921 | $6.60M | 0.00% | +35,478+69.0% | Added |
| Raymond James Financial Inc | 85,998 | $6.53M | 0.00% | +2,873+3.5% | Added |
| Pinnacle Associates Ltd | 83,431 | $6.34M | 0.08% | −5,161−5.8% | Reduced |
| Royce & Associates LP | 80,794 | $6.14M | 0.06% | +48,015+146.5% | Added |
| Rafferty Asset Management, LLC | 78,507 | $5.96M | 0.02% | −22,494−22.3% | Reduced |
| Great West Life Assurance Co | 78,150 | $5.94M | 0.01% | +44,166+130.0% | Added |
| TrimTabs Asset Management, LLC | 75,757 | $5.75M | 0.75% | +75,757 | New |
| Hillsdale Investment Management Inc. | 75,706 | $5.75M | 0.16% | −15,430−16.9% | Reduced |
| Canada Pension Plan Investment Board | 75,400 | $5.73M | 0.00% | +75,400 | New |
| Schroder Investment Management Group | 72,597 | $5.53M | 0.00% | +38,475+112.8% | Added |
| Alyeska Investment Group, L.P. | 72,307 | $5.49M | 0.02% | +72,307 | New |
| EAM Investors, LLC | 71,735 | $5.45M | 0.61% | +71,735 | New |
| Acadian Asset Management LLC | 69,504 | $5.27M | 0.01% | +45,354+187.8% | Added |
| California State Teachers Retirement System | 68,293 | $5.19M | 0.01% | +3,766+5.8% | Added |
| HRT Financial LP | 67,064 | $5.09M | 0.02% | +55,282+469.2% | Added |
| Sector Gamma AS | 61,923 | $4.70M | 1.07% | −56,189−47.6% | Reduced |
| Rock Springs Capital Management LP | 61,879 | $4.70M | 0.24% | +61,879 | New |
| Victory Capital Management Inc | 56,571 | $4.30M | 0.00% | −19,542−25.7% | Reduced |
| Thrivent Financial for Lutherans | 55,169 | $4.19M | 0.01% | +55,169 | New |
| Assenagon Asset Management S.A. | 54,170 | $4.11M | 0.01% | −53,478−49.7% | Reduced |
| Norges Bank | 53,807 | $4.09M | 0.00% | +53,807 | New |
| Segall Bryant & Hamill, LLC | 50,431 | $3.83M | 0.05% | +12,969+34.6% | Added |