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PTC Therapeutics, Inc.

PTCT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001070081

In the last 90 days, PTC Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 382 institutions reported holding it in 13F filings for Q2 2026, worth $8.20B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in PTC Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
353
+64 vs. Q3 2025
Shares held
92.7M
+10.1M (+12.3%) vs. Q3 2025
Total value
$7.04B
+$1.97B (+39.0%) vs. Q3 2025
New holders
101
126 more added
Sold out
37
96 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTCT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 353 institutions
Q1 2021: 208 institutionsQ2 2021: 183 institutionsQ3 2021: 184 institutionsQ4 2021: 179 institutionsQ1 2022: 184 institutionsQ2 2022: 182 institutionsQ3 2022: 213 institutionsQ4 2022: 203 institutionsQ1 2023: 203 institutionsQ2 2023: 206 institutionsQ3 2023: 181 institutionsQ4 2023: 174 institutionsQ1 2024: 184 institutionsQ2 2024: 199 institutionsQ3 2024: 203 institutionsQ4 2024: 240 institutionsQ1 2025: 261 institutionsQ2 2025: 284 institutionsQ3 2025: 294 institutionsQ4 2025: 353 institutionsQ1 2026: 352 institutionsQ2 2026: 382 institutions
Value heldQ4 2025: $7.04B
Q1 2021: $3.52BQ2 2021: $3.13BQ3 2021: $2.77BQ4 2021: $3.00BQ1 2022: $2.76BQ2 2022: $2.97BQ3 2022: $3.83BQ4 2022: $2.94BQ1 2023: $3.81BQ2 2023: $3.30BQ3 2023: $1.83BQ4 2023: $2.33BQ1 2024: $2.48BQ2 2024: $2.44BQ3 2024: $2.93BQ4 2024: $3.51BQ1 2025: $4.02BQ2 2025: $3.90BQ3 2025: $5.07BQ4 2025: $7.04BQ1 2026: $6.51BQ2 2026: $8.20B
Institutions holding PTCT and their total value by quarter
QuarterHoldersValue
Q2 2026382$8.20B
Q1 2026352$6.51B
Q4 2025353$7.04B
Q3 2025294$5.07B
Q2 2025284$3.90B
Q1 2025261$4.02B
Q4 2024240$3.51B
Q3 2024203$2.93B
Q2 2024199$2.44B
Q1 2024184$2.48B
Q4 2023174$2.33B
Q3 2023181$1.83B
Q2 2023206$3.30B
Q1 2023203$3.81B
Q4 2022203$2.94B
Q3 2022213$3.83B
Q2 2022182$2.97B
Q1 2022184$2.76B
Q4 2021179$3.00B
Q3 2021184$2.77B
Q2 2021183$3.13B
Q1 2021208$3.52B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding PTC Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding PTCT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
ProShare Advisors LLC18,689$1.42M0.00%+2,569+15.9%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys19,877$1.51M0.01%+19,877New
Arizona State Retirement System20,046$1.52M0.01%−1,055−5.0%Reduced
Martingale Asset Management L P20,115$1.53M0.04%+6,512+47.9%Added
Verition Fund Management LLC20,200$1.53M0.01%−16,870−45.5%Reduced
State Board of Administration of Florida Retirement System20,211$1.54M0.00%00.0%Unchanged
STRS Ohio20,600$1.56M0.01%−2,000−8.8%Reduced
Police & Firemen's Retirement System of New Jersey21,067$1.60M0.01%−449−2.1%Reduced
Yousif Capital Management, LLC22,228$1.62M0.02%+22,228New
QRG Capital Management, Inc.21,711$1.65M0.02%−12,348−36.3%Reduced
Millennium Management LLC22,494$1.71M0.00%−1,033,987−97.9%Reduced
Jackson Creek Investment Advisors LLC22,603$1.72M0.51%−14,113−38.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)22,832$1.73M0.00%+1,901+9.1%Added
Amalgamated Bank23,122$1.76M0.01%+20,604+818.3%Added
Lazard Asset Management LLC23,200$1.76M0.00%+4,255+22.5%Added
OrbiMed Advisors LLC23,200$1.76M0.04%+23,200New
Rathbone Brothers plc23,500$1.79M0.01%00.0%Unchanged
Two Sigma Investments, LP24,310$1.85M0.00%−31−0.1%Reduced
State of New Jersey Common Pension Fund D24,402$1.85M0.01%−19,078−43.9%Reduced
Ritholtz Wealth Management24,524$1.86M0.03%+24,524New
Handelsbanken Fonder AB25,200$1.91M0.01%−2,900−10.3%Reduced
Hussman Strategic Advisors, Inc.25,200$1.91M0.46%−37,800−60.0%Reduced
Phocas Financial Corp.25,482$1.94M0.25%−11,752−31.6%Reduced
Credit Agricole S A26,316$2.00M0.01%+26,316New
Burney Co26,569$2.02M0.06%+26,569New
Convergence Investment Partners, LLC27,193$2.07M0.41%−735−2.6%Reduced
Bridgeway Capital Management, LLC28,100$2.13M0.04%−13,700−32.8%Reduced
New York State Common Retirement Fund28,915$2.20M0.00%−1,601−5.2%Reduced
Los Angeles Capital Management LLC32,421$2.21M0.01%−15,026−31.7%Reduced
Private Capital Advisors, Inc.29,113$2.21M0.23%+13,051+81.3%Added
Virginia Retirement Systems Et Al30,850$2.34M0.01%−6,100−16.5%Reduced
Profund Advisors LLC31,853$2.42M0.07%+9,591+43.1%Added
State of Tennessee, Treasury Department32,634$2.46M0.01%+32,634New
Citigroup Inc32,661$2.48M0.00%+18,275+127.0%Added
Intech Investment Management LLC34,691$2.64M0.02%+6,413+22.7%Added
O'Shaughnessy Asset Management, LLC35,350$2.69M0.01%+35,350New
Ieq Capital, LLC35,681$2.71M0.01%+3,348+10.4%Added
Ishara Investments LP36,000$2.73M3.18%+36,000New
Engineers Gate Manager LP36,709$2.79M0.03%+25,486+227.1%Added
Louisiana State Employees Retirement System36,800$2.80M0.05%+36,800New
Creative Planning37,766$2.87M0.00%+6,842+22.1%Added
Harbor Capital Advisors, Inc.39,005$2.96M0.23%−10,595−21.4%Reduced
Boothbay Fund Management, LLC39,735$3.02M0.08%−70,896−64.1%Reduced
Horizon Investments, LLC40,333$3.06M0.04%+40,333New
Teachers Retirement System of the State of Kentucky40,858$3.10M0.02%+19,000+86.9%Added
Guggenheim Capital LLC41,238$3.13M0.02%+24,450+145.6%Added
MetLife Investment Management43,554$3.31M0.02%−1,737−3.8%Reduced
Massachusetts Financial Services Co44,593$3.39M0.00%−1,477−3.2%Reduced
New York State Teachers Retirement System44,637$3.39M0.01%+44,637New
State of Alaska, Department of Revenue45,346$3.44M0.04%+41,038+952.6%Added
State of Wisconsin Investment Board46,775$3.55M0.01%−12,010−20.4%Reduced
Illinois Municipal Retirement Fund49,936$3.79M0.05%+49,936New
Mirae Asset Global ETFs Holdings Ltd.50,143$3.81M0.01%−4,449−8.1%Reduced
Segall Bryant & Hamill, LLC50,431$3.83M0.05%+12,969+34.6%Added
Norges Bank53,807$4.09M0.00%+53,807New
Assenagon Asset Management S.A.54,170$4.11M0.01%−53,478−49.7%Reduced
Thrivent Financial for Lutherans55,169$4.19M0.01%+55,169New
Victory Capital Management Inc56,571$4.30M0.00%−19,542−25.7%Reduced
Rock Springs Capital Management LP61,879$4.70M0.24%+61,879New
Sector Gamma AS61,923$4.70M1.07%−56,189−47.6%Reduced
HRT Financial LP67,064$5.09M0.02%+55,282+469.2%Added
California State Teachers Retirement System68,293$5.19M0.01%+3,766+5.8%Added
Acadian Asset Management LLC69,504$5.27M0.01%+45,354+187.8%Added
EAM Investors, LLC71,735$5.45M0.61%+71,735New
Alyeska Investment Group, L.P.72,307$5.49M0.02%+72,307New
Schroder Investment Management Group72,597$5.53M0.00%+38,475+112.8%Added
Canada Pension Plan Investment Board75,400$5.73M0.00%+75,400New
Hillsdale Investment Management Inc.75,706$5.75M0.16%−15,430−16.9%Reduced
TrimTabs Asset Management, LLC75,757$5.75M0.75%+75,757New
Great West Life Assurance Co78,150$5.94M0.01%+44,166+130.0%Added
Rafferty Asset Management, LLC78,507$5.96M0.02%−22,494−22.3%Reduced
Royce & Associates LP80,794$6.14M0.06%+48,015+146.5%Added
Pinnacle Associates Ltd83,431$6.34M0.08%−5,161−5.8%Reduced
Raymond James Financial Inc85,998$6.53M0.00%+2,873+3.5%Added
Wells Fargo & Company86,921$6.60M0.00%+35,478+69.0%Added
SEI Investments Co92,089$6.99M0.01%+33,748+57.8%Added
Alliancebernstein L.P.94,308$7.16M0.00%+2,291+2.5%Added
Castleark Management LLC96,860$7.36M0.22%+96,860New
WCM Investment Management, LLC110,267$8.40M0.02%−36,798−25.0%Reduced
Neuberger Berman Group LLC111,590$8.48M0.01%+107,983+2,993.7%Added
Federated Hermes, Inc.112,566$8.55M0.01%+97,750+659.8%Added
Ikarian Capital, LLC118,657$9.01M1.17%−161,894−57.7%Reduced
UBS Asset Management Americas Inc131,893$10.0M0.00%+1,995+1.5%Added
Adage Capital Partners GP, L.L.C.141,000$10.7M0.02%−150,000−51.5%Reduced
Swiss National Bank141,065$10.7M0.01%+2,800+2.0%Added
Ameriprise Financial Inc147,584$11.2M0.00%+136,954+1,288.4%Added
Universal- Beteiligungs- und Servicegesellschaft mbH151,401$11.5M0.02%+19,300+14.6%Added
First Trust Advisors LP155,596$11.8M0.01%+33,741+27.7%Added
BI Asset Management Fondsmaeglerselskab A/S159,477$12.1M0.11%+64,472+67.9%Added
Parkman Healthcare Partners LLC160,179$12.2M1.16%−42,184−20.8%Reduced
Prudential Financial Inc183,185$13.9M0.02%+95,745+109.5%Added
Boxer Capital Management, LLC200,000$15.2M3.33%00.0%Unchanged
Rhumbline Advisers207,950$15.8M0.01%+94,046+82.6%Added
Barclays PLC220,196$16.7M0.01%−19,453−8.1%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main220,847$16.8M0.01%−16,277−6.9%Reduced
Deutsche Bank AG231,268$17.6M0.01%+151,380+189.5%Added
Pacer Advisors, Inc.235,653$17.9M0.05%−268,313−53.2%Reduced
Mackenzie Financial Corp236,909$18.0M0.02%+35,117+17.4%Added
Marshall Wace, LLP247,746$18.8M0.02%+90,007+57.1%Added
Empowered Funds, LLC250,412$19.0M0.32%+206,707+473.0%Added