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Personalis, Inc.

PSNL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001527753

In the last 90 days, Personalis, Inc. insiders filed 0 open-market purchases and 6 sales; 158 institutions reported holding it in 13F filings for Q2 2026, worth $1.14B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Personalis, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
+17 vs. Q3 2025
Shares held
81.0M
+16.3M (+25.2%) vs. Q3 2025
Total value
$644.8M
+$222.9M (+52.8%) vs. Q3 2025
New holders
31
37 more added
Sold out
14
38 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PSNL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 126 institutions
Q1 2021: 134 institutionsQ2 2021: 136 institutionsQ3 2021: 120 institutionsQ4 2021: 108 institutionsQ1 2022: 125 institutionsQ2 2022: 99 institutionsQ3 2022: 81 institutionsQ4 2022: 80 institutionsQ1 2023: 63 institutionsQ2 2023: 66 institutionsQ3 2023: 63 institutionsQ4 2023: 69 institutionsQ1 2024: 71 institutionsQ2 2024: 69 institutionsQ3 2024: 83 institutionsQ4 2024: 107 institutionsQ1 2025: 104 institutionsQ2 2025: 105 institutionsQ3 2025: 109 institutionsQ4 2025: 126 institutionsQ1 2026: 140 institutionsQ2 2026: 158 institutions
Value heldQ4 2025: $644.8M
Q1 2021: $763.1MQ2 2021: $807.9MQ3 2021: $604.2MQ4 2021: $456.2MQ1 2022: $265.3MQ2 2022: $105.6MQ3 2022: $83.9MQ4 2022: $55.0MQ1 2023: $75.0MQ2 2023: $49.0MQ3 2023: $30.0MQ4 2023: $46.1MQ1 2024: $33.2MQ2 2024: $25.7MQ3 2024: $157.6MQ4 2024: $298.2MQ1 2025: $192.4MQ2 2025: $396.6MQ3 2025: $421.8MQ4 2025: $644.8MQ1 2026: $538.8MQ2 2026: $1.14B
Institutions holding PSNL and their total value by quarter
QuarterHoldersValue
Q2 2026158$1.14B
Q1 2026140$538.8M
Q4 2025126$644.8M
Q3 2025109$421.8M
Q2 2025105$396.6M
Q1 2025104$192.4M
Q4 2024107$298.2M
Q3 202483$157.6M
Q2 202469$25.7M
Q1 202471$33.2M
Q4 202369$46.1M
Q3 202363$30.0M
Q2 202366$49.0M
Q1 202363$75.0M
Q4 202280$55.0M
Q3 202281$83.9M
Q2 202299$105.6M
Q1 2022125$265.3M
Q4 2021108$456.2M
Q3 2021120$604.2M
Q2 2021136$807.9M
Q1 2021134$763.1M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Personalis, Inc.; share changes are against Q3 2025.

Institutions holding PSNL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Goldman Sachs Group Inc342,475$2.73M0.00%−231,506−40.3%Reduced
Northern Trust Corp354,918$2.83M0.00%−38,866−9.9%Reduced
First Manhattan Co373,822$2.98M0.01%+373,822New
Portolan Capital Management, LLC379,197$3.02M0.16%+379,197New
State of Michigan Retirement System493,798$3.93M0.02%00.0%Unchanged
Sumitomo Mitsui Trust Holdings, Inc.518,441$4.13M0.00%−72,555−12.3%Reduced
Nikko Asset Management Americas, Inc.518,441$4.13M0.05%−72,555−12.3%Reduced
Howland Capital Management LLC547,115$4.36M0.17%+216,442+65.5%Added
Next Century Growth Investors LLC624,363$4.97M0.35%+624,363New
PFM Health Sciences, LP805,817$6.41M0.65%+805,817New
Dimensional Fund Advisors LP983,174$7.83M0.00%+9,519+1.0%Added
State Street Corp1,050,590$8.36M0.00%+124,243+13.4%Added
Geode Capital Management, LLC1,297,807$10.3M0.00%−35,734−2.7%Reduced
Price T Rowe Associates Inc1,448,585$11.5M0.00%+1,347,439+1,332.2%Added
Blue Water Life Science Advisors, LLC1,676,300$13.3M8.37%00.0%Unchanged
Kennedy Capital Management, Inc.1,712,652$13.6M0.29%−222,426−11.5%Reduced
AIGH Capital Management LLC2,900,000$23.1M6.82%−992,101−25.5%Reduced
Standard Life Aberdeen plc3,249,895$25.9M0.04%+861,948+36.1%Added
Vanguard Group Inc3,253,797$25.9M0.00%+247,387+8.2%Added
BlackRock, Inc.5,319,508$42.3M0.00%−325,291−5.8%Reduced
Ameriprise Financial Inc6,287,151$50.0M0.01%+5,988,126+2,002.6%Added
ARK Investment Management LLCSuperinvestorARK Invest7,879,087$62.7M0.42%−31,104−0.4%Reduced
Lightspeed Management Company, L.L.C.8,160,734$65.0M4.65%00.0%Unchanged
T. Rowe Price Investment Management, Inc.10,780,290$85.8M0.05%+7,896,714+273.9%Added
Merck & Co., Inc.14,044,943$111.8M40.47%00.0%Unchanged
Berbice Capital Management LLC320––00.0%Unchanged
Millennium Management LLC0$00.00%−1,210,754−100.0%Sold out
JBF Capital, Inc.0$00.00%−166,104−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−46,193−100.0%Sold out
Sanctuary Advisors, LLC0$00.00%−39,974−100.0%Sold out
Ieq Capital, LLC0$00.00%−22,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−18,886−100.0%Sold out
Atom Investors LP0$00.00%−18,043−100.0%Sold out
Parallel Advisors, LLC0$00.00%−16,522−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−14,855−100.0%Sold out
FourThought Financial Partners, LLC0$00.00%−13,145−100.0%Sold out
Group One Trading, L.P.0$00.00%−2,142−100.0%Sold out
GPS Wealth Strategies Group, LLC0$00.00%−1,000−100.0%Sold out
Rise Advisors, LLC0$00.00%−142−100.0%Sold out
Principal Securities, Inc.0$00.00%−134−100.0%Sold out