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NuCana plc

NCNA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001709626

No open-market purchases or sales by NuCana plc insiders were filed in the last 90 days; 10 institutions reported holding it in 13F filings for Q2 2026, worth $167.9K in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in NuCana plc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
38
+7 vs. Q3 2021
Shares held
18.8M
+360.6K (+2.0%) vs. Q3 2021
Total value
$44.7M
−$2.79M (−5.9%) vs. Q3 2021
New holders
14
5 more added
Sold out
7
6 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting NCNA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 38 institutions
Q1 2021: 35 institutionsQ2 2021: 33 institutionsQ3 2021: 31 institutionsQ4 2021: 38 institutionsQ1 2022: 34 institutionsQ2 2022: 26 institutionsQ3 2022: 28 institutionsQ4 2022: 27 institutionsQ1 2023: 25 institutionsQ2 2023: 21 institutionsQ3 2023: 21 institutionsQ4 2023: 24 institutionsQ1 2024: 23 institutionsQ2 2024: 15 institutionsQ3 2024: 18 institutionsQ4 2024: 20 institutionsQ1 2025: 12 institutionsQ2 2025: 17 institutionsQ3 2025: 10 institutionsQ4 2025: 9 institutionsQ1 2026: 8 institutionsQ2 2026: 10 institutions
Value heldQ4 2021: $44.7M
Q1 2021: $129.0MQ2 2021: $58.7MQ3 2021: $47.5MQ4 2021: $44.7MQ1 2022: $15.0MQ2 2022: $10.0MQ3 2022: $14.7MQ4 2022: $9.18MQ1 2023: $13.2MQ2 2023: $10.8MQ3 2023: $8.34MQ4 2023: $3.89MQ1 2024: $2.05MQ2 2024: $866.6KQ3 2024: $589.9KQ4 2024: $532.0KQ1 2025: $238.2KQ2 2025: $38.8KQ3 2025: $835.6KQ4 2025: $643.4KQ1 2026: $79.5KQ2 2026: $167.9K
Institutions holding NCNA and their total value by quarter
QuarterHoldersValue
Q2 202610$167.9K
Q1 20268$79.5K
Q4 20259$643.4K
Q3 202510$835.6K
Q2 202517$38.8K
Q1 202512$238.2K
Q4 202420$532.0K
Q3 202418$589.9K
Q2 202415$866.6K
Q1 202423$2.05M
Q4 202324$3.89M
Q3 202321$8.34M
Q2 202321$10.8M
Q1 202325$13.2M
Q4 202227$9.18M
Q3 202228$14.7M
Q2 202226$10.0M
Q1 202234$15.0M
Q4 202138$44.7M
Q3 202131$47.5M
Q2 202133$58.7M
Q1 202135$129.0M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding NuCana plc; share changes are against Q3 2021.

Institutions holding NCNA in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Sofinnova Investments, Inc.5,599,999$13.3M0.85%00.0%Unchanged
Baillie Gifford & Co3,659,030$8.71M0.00%00.0%Unchanged
Abingworth LLP3,333,333$7.93M1.92%00.0%Unchanged
Capital International Investors2,977,153$7.09M0.00%00.0%Unchanged
Opaleye Management Inc.1,189,000$2.83M0.60%+709,400+147.9%Added
FMR LLC624,329$1.49M0.00%−2,771−0.4%Reduced
Renaissance Technologies LLC344,333$820.0K0.00%−438,400−56.0%Reduced
Acadian Asset Management LLC198,522$470.0K0.00%−187,603−48.6%Reduced
Skandinaviska Enskilda Banken AB (publ)150,000$359.0K0.00%+150,000New
Citadel Advisors LLC144,400$344.0K0.00%+144,400New
Bank of America Corp75,746$180.0K0.00%+35,069+86.2%Added
Truist Financial Corp70,100$167.0K0.00%00.0%Unchanged
State Street Corp66,948$159.0K0.00%+1,234+1.9%Added
Goldman Sachs Group Inc50,952$121.0K0.00%+33,497+191.9%Added
Private Advisor Group, LLC47,050$112.0K0.00%+47,050New
Legal & General Group Plc46,434$111.0K0.00%+46,434New
Virtu Financial LLC29,107$69.0K0.01%+29,107New
Moors & Cabot, Inc.25,000$60.0K0.00%00.0%Unchanged
Algert Global LLC19,980$48.0K0.01%+19,980New
Horizon Kinetics Asset Management LLC19,467$46.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)16,825$40.0K0.00%+16,174+2,484.5%Added
Millennium Management LLC14,069$33.0K0.00%+14,069New
Jane Street Group, LLC12,404$30.0K0.00%+12,404New
Susquehanna Fundamental Investments, LLC11,800$28.0K0.00%+11,800New
Wells Fargo & Company11,055$26.0K0.00%−2,500−18.4%Reduced
Traynor Capital Management, Inc.11,000$26.0K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co7,100$17.0K0.00%+7,100New
Plante Moran Financial Advisors, LLC6,000$14.0K0.00%00.0%Unchanged
Morgan Stanley5,540$13.0K0.00%−7,652−58.0%Reduced
Parallel Advisors, LLC4,885$12.0K0.00%00.0%Unchanged
AllSquare Wealth Management LLC5,130$12.0K0.01%+5,130New
Migdal Insurance & Financial Holdings Ltd.3,545$8.00K0.00%−2,137−37.6%Reduced
UBS Group AG2,811$7.00K0.00%+2,811New
Activest Wealth Management836$2.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA300$7140.00%+300New
Captrust Financial Advisors200$00.00%00.0%Unchanged
Advisor Group Holdings, Inc.154$00.00%00.0%Unchanged
Castleview Partners, LLC333––+333New
BlackRock Inc.0$00.00%−237,259−100.0%Sold out
Commonwealth of Pennsylvania Public School Empls Retrmt Sys0$00.00%−21,351−100.0%Sold out
Squarepoint Ops LLC0$00.00%−16,612−100.0%Sold out
New York State Common Retirement Fund0$00.00%−9,203−100.0%Sold out
Barclays PLC0$00.00%−2−100.0%Sold out
Royal Bank of Canada0$00.00%−189−100.0%Sold out
Gerber Kawasaki Wealth & Investment Management0$00.00%−1−100.0%Sold out