| Sep 15, 20264:30 PM ET | Sep 14, 2026 | Davidson Michael H.Chief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +10K | $22.65 | +$226.5K | 792.92K | +1.3% | SEC↗ |
| Sep 9, 20264:30 PM ET | Sep 4, 2026 | Smither John WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −1.6K | $25.32 | −$40.51K | 8.76K | −15.4% | SEC↗ |
| Aug 25, 20264:30 PM ET | Aug 24, 2026 | Kastelein Johannes Jacob PieterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −125K | $26.91 | −$3.36M | 69.3K | −64.3% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 22, 20264:05 PM ET | Jul 20, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −105K | $30.3396 | −$3.19M | 24.35K | −81.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 24, 2026 | Jun 22, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −40K | $30.204 | −$1.21M | 24.35K | −62.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 27, 2026 | May 26, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −65K | $35.69 | −$2.32M | 24.35K | −72.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 12, 2026 | Mar 11, 2026 | LANGE LOUIS GDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −44.62K | $30.4182 | −$1.36M | 10.36K | −81.2% | SEC↗ |
| Mar 10, 2026 | Mar 6, 2026 | LANGE LOUIS GDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −28.19K | $29.41 | −$828.95K | 0 | −100.0% | SEC↗ |
| Mar 9, 2026 | Mar 5 – Mar 9, 2026 | Kastelein Johannes Jacob PieterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −300K | $30.3029 | −$9.09M | 69.3K | −81.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 2, 2026 | Mar 2, 2026 | Davidson Michael H.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −443.71K | $33.25 | −$14.75M | 174.14K | −71.8% | SEC↗ |
| Feb 26, 2026 | Feb 24 – Feb 26, 2026 | Davidson Michael H.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −306.29K | $34.5261 | −$10.58M | 174.14K | −63.8% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 24, 2026 | Feb 20, 2026 | Kastelein Johannes Jacob PieterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −45.48K | $35.3114 | −$1.61M | 53.5K | −45.9% | SEC↗ |
| Jan 29, 2026 | Jan 27 – Jan 28, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −72.43K | $32.2508 | −$2.34M | 24.35K | −74.8% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 27, 2026 | Jan 23 – Jan 26, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −72.57K | $33.2889 | −$2.42M | 24.35K | −74.9% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 22, 2026 | Jan 20 – Jan 21, 2026 | Somaiya Mayur IanChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | $32.6062 | −$3.26M | 58.38K | −63.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 9, 2026 | Jan 7, 2026 | Davidson Michael H.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −11.58K | – | – | 378.86K | −3.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 7, 2026 | Jan 5, 2026 | Kastelein Johannes Jacob PieterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −6K | $33.25 | −$199.5K | 73.48K | −7.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 7, 2026 | Jan 5, 2026 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −2.65K | $33.25 | −$88.01K | 12.35K | −17.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 7, 2026 | Jan 5, 2026 | Somaiya Mayur IanChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −5.12K | $33.25 | −$170.17K | 32.88K | −13.5% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 29, 2025 | Dec 23 – Dec 26, 2025 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −145K | $35.8396 | −$5.2M | 15K | −90.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 17, 2025 | Sep 15, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +660 | $23.70 | +$15.64K | 3.03M | 0.0% | SEC↗ |
| Sep 10, 2025 | Sep 8, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +1.26K | $24.99 | +$31.49K | 3.03M | 0.0% | SEC↗ |
| Sep 10, 2025 | Sep 9, 2025 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −150K | $25.8268 | −$3.87M | 15K | −90.9% | SEC↗ |
| Sep 5, 2025 | Sep 3, 2025 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −18.07K | $25.09 | −$453.45K | 15K | −54.6% | SEC↗ |
| Aug 27, 2025 | Aug 25, 2025 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −8.27K | $24.86 | −$205.57K | 15K | −35.5% | SEC↗ |
| Aug 25, 2025 | Aug 21 – Aug 22, 2025 | Kastelein Johannes Jacob PieterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | $24.7164 | −$2.47M | 69.3K | −59.1% | SEC↗ |
| Aug 13, 2025 | Aug 11, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +471 | $23.98 | +$11.29K | 3.03M | 0.0% | SEC↗ |
| Jul 17, 2025 | Jul 15 – Jul 16, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −98.61K | $21.2617 | −$2.1M | 44K | −69.1% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 26, 2025 | Jun 24 – Jun 25, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +3.78K | $18.3733 | +$69.45K | 3.03M | +0.1% | SEC↗ |
| Jun 18, 2025 | Jun 16, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +8.58K | $19.50 | +$167.39K | 3.02M | +0.3% | SEC↗ |
| Jun 18, 2025 | Jun 16, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | $19.2914 | −$1.93M | 44K | −69.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 19, 2025 | May 15, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | – | – | 44K | −69.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2025 | Apr 15, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | – | – | 44K | −69.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 28, 2025 | Mar 26, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +1.14K | $22.49 | +$25.53K | 3.01M | 0.0% | SEC↗ |
| Mar 28, 2025 | Mar 26, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −16.54K | – | – | 44K | −27.3% | SEC↗ |
| Mar 28, 2025 | Mar 26, 2025 | Davidson Michael H.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −12.26K | – | – | 390.44K | −3.0% | SEC↗ |
| Mar 19, 2025 | Mar 17, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | – | – | 44K | −69.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 6, 2025 | Mar 4, 2025 | Topper James NDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares | +4.01K | $21.02 | +$84.19K | 3.01M | +0.1% | SEC↗ |
| Mar 5, 2025 | Mar 4, 2025 | Kooij Louise FrederikaChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −150K | $20.37 | −$3.06M | 15K | −90.9% | SEC↗ |
| Feb 20, 2025 | Feb 18 – Feb 19, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −100K | – | – | 44K | −69.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 31, 2025 | Jan 29 – Jan 30, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −70.44K | – | – | 44K | −61.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 29, 2025 | Jan 27 – Jan 28, 2025 | Somaiya Mayur IanChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −61.88K | – | – | 38K | −62.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 29, 2025 | Jan 27 – Jan 28, 2025 | Kling Douglas FChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −129.56K | – | – | 44K | −74.6% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 2, 20254:15 PM ET | Dec 30, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −29.85K | $25.5369 | −$762.17K | 10.66M | −0.3% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 30, 20244:15 PM ET | Dec 26 – Dec 27, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −74.91K | $25.9768 | −$1.95M | 10.69M | −0.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 26, 20244:15 PM ET | Dec 20 – Dec 24, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −91.07K | $25.58 | −$2.33M | 10.76M | −0.8% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 20, 20244:25 PM ET | Dec 18 – Dec 19, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −157.23K | $25.8641 | −$4.07M | 10.85M | −1.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 18, 20244:15 PM ET | Dec 16 – Dec 17, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −115.48K | $25.9452 | −$3M | 11.01M | −1.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 17, 20245:05 PM ET | Dec 13, 2024 | BCIP Life Sciences Associates, LP and 9 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares · Derivative | +1.63M | $24.4999 | +$40M | 1.63M | – | SEC↗ |
| Dec 16, 20244:15 PM ET | Dec 12 – Dec 13, 2024 | Forbion Capital Fund IV Cooperatief U.A. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares | −191.76K | $25.3433 | −$4.86M | 11.12M | −1.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
