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MoonLake Immunotherapeutics

MLTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001821586

In the last 90 days, MoonLake Immunotherapeutics insiders filed 0 open-market purchases and 6 sales; 172 institutions reported holding it in 13F filings for Q2 2026, worth $1.43B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in MoonLake Immunotherapeutics as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
130
0 vs. Q3 2025
Shares held
56.4M
+18.9M (+50.3%) vs. Q3 2025
Total value
$742.9M
+$474.1M (+176.4%) vs. Q3 2025
New holders
47
55 more added
Sold out
47
23 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 130 institutions
Q1 2021: 42 institutionsQ2 2021: 46 institutionsQ3 2021: 43 institutionsQ4 2021: 45 institutionsQ1 2022: 27 institutionsQ2 2022: 23 institutionsQ3 2022: 24 institutionsQ4 2022: 33 institutionsQ1 2023: 43 institutionsQ2 2023: 83 institutionsQ3 2023: 118 institutionsQ4 2023: 125 institutionsQ1 2024: 114 institutionsQ2 2024: 111 institutionsQ3 2024: 109 institutionsQ4 2024: 116 institutionsQ1 2025: 136 institutionsQ2 2025: 130 institutionsQ3 2025: 134 institutionsQ4 2025: 130 institutionsQ1 2026: 147 institutionsQ2 2026: 172 institutions
Value heldQ4 2025: $742.9M
Q1 2021: $108.9MQ2 2021: $115.8MQ3 2021: $111.1MQ4 2021: $112.8MQ1 2022: $123.4MQ2 2022: $190.1MQ3 2022: $291.4MQ4 2022: $396.4MQ1 2023: $843.2MQ2 2023: $2.86BQ3 2023: $3.21BQ4 2023: $3.53BQ1 2024: $2.99BQ2 2024: $2.67BQ3 2024: $3.14BQ4 2024: $3.43BQ1 2025: $2.34BQ2 2025: $2.77BQ3 2025: $269.7MQ4 2025: $742.9MQ1 2026: $1.17BQ2 2026: $1.43B
Institutions holding MLTX and their total value by quarter
QuarterHoldersValue
Q2 2026172$1.43B
Q1 2026147$1.17B
Q4 2025130$742.9M
Q3 2025134$269.7M
Q2 2025130$2.77B
Q1 2025136$2.34B
Q4 2024116$3.43B
Q3 2024109$3.14B
Q2 2024111$2.67B
Q1 2024114$2.99B
Q4 2023125$3.53B
Q3 2023118$3.21B
Q2 202383$2.86B
Q1 202343$843.2M
Q4 202233$396.4M
Q3 202224$291.4M
Q2 202223$190.1M
Q1 202227$123.4M
Q4 202145$112.8M
Q3 202143$111.1M
Q2 202146$115.8M
Q1 202142$108.9M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding MoonLake Immunotherapeutics; share changes are against Q3 2025.

Institutions holding MLTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc19,751,284$260.3M8.76%00.0%Unchanged
Deep Track Capital, LP4,610,071$60.8M1.39%+4,610,071New
Cormorant Asset Management, LP4,355,433$57.4M3.25%+2,361,260+118.4%Added
D. E. Shaw & Co., Inc.2,480,767$32.7M0.02%+2,480,767New
Janus Henderson Group PLC2,095,988$27.7M0.01%+2,084,888+18,782.8%Added
Logos Global Management LP1,750,000$23.1M1.54%+1,750,000New
Jane Street Group, LLC1,682,148$22.2M0.03%+1,660,170+7,553.8%Added
Balyasny Asset Management LLC1,571,071$20.7M0.04%−128,164−7.5%Reduced
Morgan Stanley1,044,581$13.8M0.00%+787,926+307.0%Added
Vivo Capital, LLC1,000,000$13.2M0.85%+1,000,000New
Price T Rowe Associates Inc959,553$12.6M0.00%+136,596+16.6%Added
JPMorgan Chase & Co837,739$11.0M0.00%+663,578+381.0%Added
Millennium Management LLC802,722$10.6M0.01%+713,550+800.2%Added
Two Sigma Investments, LP784,811$10.3M0.02%+330,543+72.8%Added
Point72 Asset Management, L.P.772,500$10.2M0.02%+762,700+7,782.7%Added
Nuveen, LLC637,434$8.40M0.00%+1,735+0.3%Added
HRT Financial LP635,901$8.38M0.03%+492,626+343.8%Added
Susquehanna International Group, LLP549,236$7.24M0.01%+354,495+182.0%Added
Jefferies Financial Group Inc.500,000$6.59M0.05%+475,000+1,900.0%Added
Voleon Capital Management LP499,099$6.58M0.14%+458,826+1,139.3%Added
Jump Financial, LLC425,559$5.61M0.07%+425,559New
Soleus Capital Management, L.P.400,000$5.27M0.22%+400,000New
Citadel Advisors LLC380,890$5.02M0.00%+331,556+672.1%Added
Rhenman & Partners Asset Management AB364,000$4.80M0.45%+157,000+75.8%Added
StemPoint Capital LP348,401$4.59M0.79%+348,401New
Weiss Asset Management LP332,961$4.39M0.06%+332,961New
Schonfeld Strategic Advisors LLC322,261$4.25M0.02%−643,144−66.6%Reduced
BlackRock, Inc.286,593$3.78M0.00%+161,212+128.6%Added
Boxer Capital Management, LLC275,000$3.62M0.79%+25,000+10.0%Added
Goldman Sachs Group Inc270,665$3.57M0.00%−92,206−25.4%Reduced
Vanguard Group Inc266,150$3.51M0.00%+145,907+121.3%Added
First Turn Management, LLC262,643$3.46M0.40%00.0%Unchanged
Susquehanna Portfolio Strategies, LLC253,974$3.35M0.05%+253,974New
UBS Group AG239,020$3.15M0.00%+154,673+183.4%Added
Algert Global LLC221,616$2.92M0.05%+221,616New
ExodusPoint Capital Management, LP212,996$2.81M0.03%+212,996New
Granahan Investment Management Inc198,307$2.61M0.11%+198,307New
Eagle Health Investments LP187,600$2.47M0.54%+187,600New
Trexquant Investment LP184,319$2.43M0.02%+184,319New
Dimensional Fund Advisors LP183,552$2.42M0.00%+172,550+1,568.4%Added
Kalehua Capital Management LLC175,734$2.32M2.29%+175,734New
FMR LLC156,276$2.06M0.00%−570,656−78.5%Reduced
Renaissance Technologies LLC134,472$1.77M0.00%+134,472New
Candriam Luxembourg S.C.A.134,329$1.77M0.01%+687+0.5%Added
Two Sigma Advisers, LP131,700$1.74M0.00%+92,376+234.9%Added
Ameriprise Financial Inc130,964$1.73M0.00%+129,122+7,009.9%Added
Rice Hall James & Associates, LLC127,465$1.68M0.09%−7,370−5.5%Reduced
TD Asset Management Inc126,744$1.67M0.00%+20,134+18.9%Added
Squarepoint Ops LLC121,640$1.60M0.00%+90,950+296.4%Added
Tudor Investment Corp Et Al103,516$1.36M0.01%+103,516New
J. Goldman & Co LP101,467$1.34M0.05%+101,467New
Y-Intercept (Hong Kong) Ltd95,972$1.26M0.03%+95,972New
Gsa Capital Partners LLP89,236$1.18M0.10%+89,236New
Walleye Trading LLC87,390$1.15M0.02%+33,690+62.7%Added
Manufacturers Life Insurance Company, The85,570$1.13M0.00%+20,314+31.1%Added
Brevan Howard Capital Management LP78,638$1.04M0.02%+78,638New
Walleye Capital LLC75,752$998.4K0.01%+75,752New
Geode Capital Management, LLC72,606$956.4K0.00%+10,221+16.4%Added
Fox Run Management, L.L.C.71,962$948.5K0.15%+60,562+531.2%Added
Congress Asset Management Co71,096$937.0K0.01%−2,269−3.1%Reduced
Jain Global LLC70,611$930.7K0.01%+70,611New
Lion Point Capital, LP67,500$889.6K4.60%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.61,948$817.0K0.00%+61,676+22,675.0%Added
Rock Springs Capital Management LP61,700$813.2K0.04%+33,500+118.8%Added
Swiss National Bank61,500$810.6K0.00%+18,500+43.0%Added
Acuta Capital Partners, LLC59,280$781.3K0.53%+59,280New
Alps Advisors Inc58,169$766.7K0.00%+27,413+89.1%Added
State Street Corp50,973$671.8K0.00%−1,913−3.6%Reduced
Barclays PLC50,251$662.3K0.00%+50,235+313,968.8%Added
Quadrature Capital Ltd50,217$661.9K0.01%+50,217New
Woodline Partners LP49,168$648.0K0.00%−11,686−19.2%Reduced
Cinctive Capital Management LP37,194$490.2K0.03%+37,194New
IMC-Chicago, LLC36,468$480.6K0.01%+36,468New
AQR Capital Management LLC32,886$433.4K0.00%+32,886New
Group One Trading, L.P.30,476$401.7K0.01%+15,007+97.0%Added
Entropy Technologies, LP30,300$399.4K0.02%+30,300New
California State Teachers Retirement System29,296$386.1K0.00%+10,324+54.4%Added
Simplex Trading, LLC28,972$381.9K0.01%−29,257−50.2%Reduced
Axiom Investors LLC25,998$342.7K0.00%+818+3.2%Added
Graham Capital Management, L.P.24,292$320.2K0.01%+24,292New
XTX Topco Ltd22,973$302.8K0.01%−9,272−28.8%Reduced
SG Americas Securities, LLC21,888$288.0K0.00%+4,362+24.9%Added
Mariner, LLC20,159$265.7K0.00%+20,159New
Northern Trust Corp18,479$243.6K0.00%−26,536−58.9%Reduced
Virtus Investment Advisers, Inc.17,987$237.1K0.06%+15,402+595.8%Added
Legal & General Group Plc16,078$211.9K0.00%−4,827−23.1%Reduced
Skopos Labs, Inc.14,920$204.3K0.01%+14,920New
Vident Advisory, LLC15,444$203.6K0.00%+15,444New
Zurcher Kantonalbank (Zurich Cantonalbank)13,592$179.1K0.00%+7,673+129.6%Added
Bank of America Corp13,533$178.4K0.00%+9,001+198.6%Added
Campbell & CO Investment Adviser LLC13,448$177.2K0.01%+13,448New
Virtu Financial LLC12,582$166.0K0.01%+12,582New
State of Wisconsin Investment Board12,438$163.9K0.00%−274−2.2%Reduced
Centiva Capital, LP12,291$162.0K0.01%+7,791+173.1%Added
BNP Paribas Arbitrage, SA11,310$149.1K0.00%+4,014+55.0%Added
HSBC Holdings PLC11,095$146.7K0.00%+11,095New
Wells Fargo & Company10,000$131.8K0.00%+4,792+92.0%Added
Advisor Group Holdings, Inc.8,985$118.4K0.00%+8,898+10,227.6%Added
Persistent Asset Partners Ltd8,523$112.3K0.05%+8,523New
Caitong International Asset Management Co., Ltd6,950$91.6K0.02%−77,603−91.8%Reduced