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Seres Therapeutics, Inc.

MCRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001609809

In the last 90 days, Seres Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 35 institutions reported holding it in 13F filings for Q2 2026, worth $17.9M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Seres Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
36
+4 vs. Q3 2025
Shares held
2.44M
+315.7K (+14.9%) vs. Q3 2025
Total value
$36.4M
−$4.53M (−11.1%) vs. Q3 2025
New holders
9
14 more added
Sold out
5
7 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MCRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 36 institutions
Q1 2021: 154 institutionsQ2 2021: 147 institutionsQ3 2021: 133 institutionsQ4 2021: 148 institutionsQ1 2022: 131 institutionsQ2 2022: 123 institutionsQ3 2022: 120 institutionsQ4 2022: 124 institutionsQ1 2023: 123 institutionsQ2 2023: 138 institutionsQ3 2023: 134 institutionsQ4 2023: 103 institutionsQ1 2024: 99 institutionsQ2 2024: 93 institutionsQ3 2024: 77 institutionsQ4 2024: 69 institutionsQ1 2025: 63 institutionsQ2 2025: 33 institutionsQ3 2025: 32 institutionsQ4 2025: 36 institutionsQ1 2026: 33 institutionsQ2 2026: 35 institutions
Value heldQ4 2025: $36.4M
Q1 2021: $1.85BQ2 2021: $1.93BQ3 2021: $555.1MQ4 2021: $642.8MQ1 2022: $537.2MQ2 2022: $312.7MQ3 2022: $671.6MQ4 2022: $588.2MQ1 2023: $593.9MQ2 2023: $538.1MQ3 2023: $255.6MQ4 2023: $125.4MQ1 2024: $66.3MQ2 2024: $50.0MQ3 2024: $60.1MQ4 2024: $52.5MQ1 2025: $43.1MQ2 2025: $25.4MQ3 2025: $40.9MQ4 2025: $36.4MQ1 2026: $20.5MQ2 2026: $17.9M
Institutions holding MCRB and their total value by quarter
QuarterHoldersValue
Q2 202635$17.9M
Q1 202633$20.5M
Q4 202536$36.4M
Q3 202532$40.9M
Q2 202533$25.4M
Q1 202563$43.1M
Q4 202469$52.5M
Q3 202477$60.1M
Q2 202493$50.0M
Q1 202499$66.3M
Q4 2023103$125.4M
Q3 2023134$255.6M
Q2 2023138$538.1M
Q1 2023123$593.9M
Q4 2022124$588.2M
Q3 2022120$671.6M
Q2 2022123$312.7M
Q1 2022131$537.2M
Q4 2021148$642.8M
Q3 2021133$555.1M
Q2 2021147$1.93B
Q1 2021154$1.85B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Seres Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding MCRB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Flagship Pioneering Inc.1,155,850$17.2M5.32%00.0%Unchanged
Vanguard Group Inc324,214$4.82M0.00%+12,325+4.0%Added
Susquehanna International Group, LLP179,929$2.68M0.00%+179,929New
Marshall Wace, LLP120,177$1.79M0.00%−5,423−4.3%Reduced
BlackRock, Inc.103,621$1.54M0.00%+1,561+1.5%Added
Vontobel Holding Ltd.103,234$1.54M0.01%+4,723+4.8%Added
Geode Capital Management, LLC86,142$1.28M0.00%+1,160+1.4%Added
683 Capital Management, LLC52,314$778.4K0.06%+52,314New
State Street Corp33,901$504.4K0.00%+4,170+14.0%Added
Lion Point Capital, LP31,570$469.8K2.43%+4,432+16.3%Added
Citadel Advisors LLC31,418$467.5K0.00%+533+1.7%Added
Charles Schwab Investment Management Inc31,369$466.8K0.00%−34−0.1%Reduced
Schonfeld Strategic Advisors LLC29,097$433.0K0.00%+155+0.5%Added
Two Sigma Investments, LP25,749$383.1K0.00%+25,749New
Morgan Stanley25,126$373.9K0.00%+6,792+37.0%Added
American Century Companies Inc16,271$242.1K0.00%+16,271New
Northern Trust Corp14,765$219.7K0.00%+2,664+22.0%Added
Omers Administration Corp14,400$214.3K0.00%+14,400New
Invesco Ltd.14,360$213.7K0.00%+3,918+37.5%Added
Goldman Sachs Group Inc14,340$213.4K0.00%+14,340New
ExodusPoint Capital Management, LP12,737$189.5K0.00%+12,737New
Barclays PLC7,432$110.6K0.00%+6,024+427.8%Added
UBS Group AG4,226$62.9K0.00%−8,456−66.7%Reduced
SBI Securities Co., Ltd.3,482$51.8K0.00%00.0%Unchanged
FMR LLC1,740$25.9K0.00%−142−7.5%Reduced
Rachor Investment Advisory Services, LLC1,477$22.0K0.01%+1,477New
Simplex Trading, LLC1,232$18.3K0.00%−1,575−56.1%Reduced
BNP Paribas Arbitrage, SA773$11.5K0.00%+561+264.6%Added
Wells Fargo & Company260$3.87K0.00%+250+2,500.0%Added
Bank of America Corp195$2.90K0.00%−5,148−96.4%Reduced
UMA Financial Services, Inc.142$2.11K0.00%00.0%Unchanged
Sound Income Strategies, LLC8$1280.00%00.0%Unchanged
Advisor Group Holdings, Inc.8$1190.00%00.0%Unchanged
Allworth Financial LP4$600.00%+4New
SRS Capital Advisors, Inc.2$300.00%00.0%Unchanged
Royal Bank of Canada9$00.00%−287−97.0%Reduced
J. Goldman & Co LP0$00.00%−27,000−100.0%Sold out
Citigroup Inc0$00.00%−2,621−100.0%Sold out
JPMorgan Chase & Co0$00.00%−65−100.0%Sold out
US Bancorp0$00.00%−12−100.0%Sold out
Federation des caisses Desjardins du Quebec0$00.00%−3−100.0%Sold out