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Lyell Immunopharma, Inc.

LYEL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001806952

In the last 90 days, Lyell Immunopharma, Inc. insiders filed 0 open-market purchases and 10 sales; 87 institutions reported holding it in 13F filings for Q2 2026, worth $178.0M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Lyell Immunopharma, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
127
+9 vs. Q4 2023
Shares held
132.8M
+1.57M (+1.2%) vs. Q4 2023
Total value
$296.8M
+$41.6M (+16.3%) vs. Q4 2023
New holders
23
36 more added
Sold out
14
45 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LYEL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 127 institutions
Q1 2021: 0 institutionsQ2 2021: 52 institutionsQ3 2021: 62 institutionsQ4 2021: 77 institutionsQ1 2022: 79 institutionsQ2 2022: 75 institutionsQ3 2022: 93 institutionsQ4 2022: 95 institutionsQ1 2023: 99 institutionsQ2 2023: 99 institutionsQ3 2023: 106 institutionsQ4 2023: 119 institutionsQ1 2024: 127 institutionsQ2 2024: 120 institutionsQ3 2024: 117 institutionsQ4 2024: 105 institutionsQ1 2025: 112 institutionsQ2 2025: 69 institutionsQ3 2025: 59 institutionsQ4 2025: 69 institutionsQ1 2026: 74 institutionsQ2 2026: 87 institutions
Value heldQ1 2024: $296.8M
Q1 2021: $0Q2 2021: $1.29BQ3 2021: $1.22BQ4 2021: $662.2MQ1 2022: $502.7MQ2 2022: $688.6MQ3 2022: $823.5MQ4 2022: $404.8MQ1 2023: $277.9MQ2 2023: $388.7MQ3 2023: $180.1MQ4 2023: $255.2MQ1 2024: $296.8MQ2 2024: $194.2MQ3 2024: $176.6MQ4 2024: $95.9MQ1 2025: $81.8MQ2 2025: $81.9MQ3 2025: $164.9MQ4 2025: $371.9MQ1 2026: $251.1MQ2 2026: $178.0M
Institutions holding LYEL and their total value by quarter
QuarterHoldersValue
Q2 202687$178.0M
Q1 202674$251.1M
Q4 202569$371.9M
Q3 202559$164.9M
Q2 202569$81.9M
Q1 2025112$81.8M
Q4 2024105$95.9M
Q3 2024117$176.6M
Q2 2024120$194.2M
Q1 2024127$296.8M
Q4 2023119$255.2M
Q3 2023106$180.1M
Q2 202399$388.7M
Q1 202399$277.9M
Q4 202295$404.8M
Q3 202293$823.5M
Q2 202275$688.6M
Q1 202279$502.7M
Q4 202177$662.2M
Q3 202162$1.22B
Q2 202152$1.29B
Q1 20210$0

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Lyell Immunopharma, Inc.; share changes are against Q4 2023.

Institutions holding LYEL in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
MWG Management Limited20,162,332$45.0M33.29%00.0%Unchanged
Orland Properties Ltd15,093,969$33.7M19.02%00.0%Unchanged
BlackRock Inc.13,892,627$31.0M0.00%−409,593−2.9%Reduced
Vanguard Group Inc13,388,425$29.9M0.00%−215,602−1.6%Reduced
Foresite Capital Management IV, LLC8,325,000$18.6M9.38%00.0%Unchanged
WuXi AppTec Co., Ltd.8,180,678$18.2M62.06%00.0%Unchanged
Price T Rowe Associates Inc6,731,477$15.0M0.00%+92,594+1.4%Added
Alphabet Inc.5,865,125$13.1M0.52%00.0%Unchanged
Geode Capital Management, LLC4,017,021$8.96M0.00%+79,671+2.0%Added
State Street Corp3,717,963$8.29M0.00%+178,877+5.1%Added
Opaleye Management Inc.3,355,000$7.48M1.63%+3,355,000New
SC China Holding Ltd3,045,997$7.43M0.69%00.0%Unchanged
FMR LLC2,769,262$6.18M0.00%−19,465−0.7%Reduced
Millennium Management LLC2,036,672$4.54M0.00%+1,137,655+126.5%Added
MIC Capital Management UK LLP1,740,569$3.88M0.74%00.0%Unchanged
Massachusetts Financial Services Co1,540,840$3.44M0.00%+186,162+13.7%Added
Northern Trust Corp1,441,970$3.22M0.00%−33,539−2.3%Reduced
Charles Schwab Investment Management Inc1,279,412$2.85M0.00%+12,549+1.0%Added
TD Asset Management Inc963,842$2.15M0.00%+47,610+5.2%Added
Invenomic Capital Management LP871,525$1.94M0.10%+125,110+16.8%Added
Nuveen Asset Management, LLC852,055$1.90M0.00%+122,565+16.8%Added
Citadel Advisors LLC786,344$1.75M0.00%−2,690,884−77.4%Reduced
Baillie Gifford & Co656,157$1.46M0.00%−34,714−5.0%Reduced
JPMorgan Chase & Co654,622$1.46M0.00%+492,028+302.6%Added
Bank of New York Mellon Corp633,479$1.41M0.00%−27,538−4.2%Reduced
Canada Pension Plan Investment Board588,235$1.31M0.00%00.0%Unchanged
Morgan Stanley545,367$1.22M0.00%−2,230−0.4%Reduced
Manufacturers Life Insurance Company, The483,451$1.08M0.00%+19,126+4.1%Added
Two Sigma Investments, LP428,590$955.8K0.00%+187,104+77.5%Added
Goldman Sachs Group Inc425,675$949.3K0.00%−202,020−32.2%Reduced
Renaissance Technologies LLC423,500$944.0K0.00%+351,000+484.1%Added
Invesco Ltd.409,406$913.0K0.00%+98,297+31.6%Added
Clarius Group, LLC399,168$890.1K0.06%00.0%Unchanged
D. E. Shaw & Co., Inc.373,606$833.1K0.00%+373,606New
Susquehanna International Group, LLP282,579$630.2K0.00%−196,802−41.1%Reduced
Rhumbline Advisers278,171$620.3K0.00%+7,286+2.7%Added
Swiss National Bank247,400$551.7K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP245,083$547.0K0.01%+194,177+381.4%Added
Balyasny Asset Management LLC236,754$528.0K0.00%+236,754New
American Century Companies Inc236,673$527.8K0.00%+91,228+62.7%Added
Bank of America Corp219,481$489.4K0.00%−1,441,108−86.8%Reduced
OrbiMed Advisors LLC199,500$444.9K0.01%+199,500New
UBS Group AG199,178$444.2K0.00%−19,662−9.0%Reduced
Jane Street Group, LLC187,245$417.6K0.00%−116,824−38.4%Reduced
New York Life Investment Management LLC183,805$409.9K0.00%+36,338+24.6%Added
Alliancebernstein L.P.174,830$389.9K0.00%−9,420−5.1%Reduced
Caxton Associates LP174,657$389.5K0.03%+136,611+359.1%Added
BBR Partners, LLC164,041$365.8K0.03%00.0%Unchanged
Barclays PLC146,541$326.8K0.00%−116,529−44.3%Reduced
California State Teachers Retirement System130,581$291.2K0.00%−9,544−6.8%Reduced
Vestal Point Capital, LP130,000$289.9K0.02%+130,000New
Exchange Traded Concepts, LLC128,930$287.5K0.01%+45,974+55.4%Added
Legal & General Group Plc123,527$275.5K0.00%+2,362+1.9%Added
Credit Suisse AG123,256$274.9K0.00%+7,036+6.1%Added
Lighthouse Investment Partners, LLC123,002$274.3K0.02%+123,002New
XTX Topco Ltd110,719$246.9K0.03%−44,674−28.7%Reduced
Two Sigma Advisers, LP107,100$238.8K0.00%+91,700+595.5%Added
Mariner, LLC105,542$235.4K0.00%−9,362−8.1%Reduced
Cornercap Investment Counsel Inc97,126$216.6K0.03%00.0%Unchanged
Prudential Financial Inc95,957$214.0K0.00%+43,900+84.3%Added
State of Wisconsin Investment Board92,564$206.4K0.00%−11,011−10.6%Reduced
MetLife Investment Management91,094$203.1K0.00%−1,007−1.1%Reduced
Tudor Investment Corp Et Al85,992$191.8K0.00%+85,992New
Susquehanna Fundamental Investments, LLC85,751$191.2K0.01%+85,751New
American International Group, Inc.85,524$190.7K0.00%−735−0.9%Reduced
Shell Asset Management Co130,727$190.0K0.01%−13,264−9.2%Reduced
Franklin Resources Inc83,215$185.6K0.00%00.0%Unchanged
Acadian Asset Management LLC77,952$173.0K0.00%+77,952New
Squarepoint Ops LLC73,704$164.4K0.00%−231,072−75.8%Reduced
Deutsche Bank AG72,518$161.7K0.00%+2,511+3.6%Added
Janus Henderson Group PLC69,096$155.1K0.00%−230.0%Reduced
SG Americas Securities, LLC68,265$152.0K0.00%−30,956−31.2%Reduced
Wells Fargo & Company61,243$136.6K0.00%+7,870+14.7%Added
Voya Investment Management LLC58,585$130.6K0.00%−14,623−20.0%Reduced
Principal Financial Group Inc58,254$129.9K0.00%−4,661−7.4%Reduced
New York State Common Retirement Fund50,035$111.6K0.00%−1,245−2.4%Reduced
Erste Asset Management GmbH54,000$110.2K0.00%00.0%Unchanged
ProShare Advisors LLC48,986$109.2K0.00%+4,170+9.3%Added
China Universal Asset Management Co., Ltd.48,855$108.9K0.01%+19,718+67.7%Added
Citigroup Inc47,687$106.3K0.00%−28,055−37.0%Reduced
Catalyst Funds Management Pty Ltd47,300$105.5K0.03%+47,300New
AQR Capital Management LLC44,244$98.7K0.00%+14,000+46.3%Added
Virtus ETF Advisers LLC42,892$95.6K0.05%−2,940−6.4%Reduced
State of Wyoming42,858$95.6K0.02%+21,275+98.6%Added
Mercer Global Advisors Inc42,792$95.0K0.00%+42,792New
Two Sigma Securities, LLC38,128$85.0K0.00%+38,128New
Arizona State Retirement System34,610$77.2K0.00%−477−1.4%Reduced
State Board of Administration of Florida Retirement System32,253$76.1K0.00%−17,270−34.9%Reduced
Gsa Capital Partners LLP34,177$76.0K0.01%+34,177New
UBS Asset Management Americas Inc33,000$73.6K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)29,918$66.7K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC28,756$64.1K0.00%−32,911−53.4%Reduced
Jacobs Levy Equity Management, Inc28,584$63.7K0.00%+28,584New
Teacher Retirement System of Texas28,029$63.0K0.00%−989−3.4%Reduced
EntryPoint Capital, LLC26,727$59.6K0.05%−38,906−59.3%Reduced
Bleakley Financial Group, LLC25,842$57.6K0.00%−22,266−46.3%Reduced
Simplicity Wealth,LLC25,842$57.6K0.00%+25,842New
Prelude Capital Management, LLC25,304$56.4K0.00%+7,800+44.6%Added
Graham Capital Management, L.P.21,776$48.6K0.00%−4,093−15.8%Reduced
Vista Wealth Management Group, LLC20,869$46.5K0.00%00.0%Unchanged