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Kymera Therapeutics, Inc.

KYMR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001815442

In the last 90 days, Kymera Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 276 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Kymera Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
255
+53 vs. Q3 2025
Shares held
89.9M
+9.15M (+11.3%) vs. Q3 2025
Total value
$6.99B
+$2.42B (+53.1%) vs. Q3 2025
New holders
68
98 more added
Sold out
15
64 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KYMR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 255 institutions
Q1 2021: 97 institutionsQ2 2021: 110 institutionsQ3 2021: 115 institutionsQ4 2021: 128 institutionsQ1 2022: 126 institutionsQ2 2022: 101 institutionsQ3 2022: 128 institutionsQ4 2022: 121 institutionsQ1 2023: 127 institutionsQ2 2023: 129 institutionsQ3 2023: 122 institutionsQ4 2023: 137 institutionsQ1 2024: 164 institutionsQ2 2024: 157 institutionsQ3 2024: 176 institutionsQ4 2024: 181 institutionsQ1 2025: 174 institutionsQ2 2025: 210 institutionsQ3 2025: 210 institutionsQ4 2025: 255 institutionsQ1 2026: 256 institutionsQ2 2026: 276 institutions
Value heldQ4 2025: $6.99B
Q1 2021: $887.2MQ2 2021: $1.29BQ3 2021: $2.04BQ4 2021: $2.76BQ1 2022: $1.93BQ2 2022: $973.6MQ3 2022: $1.15BQ4 2022: $1.40BQ1 2023: $1.68BQ2 2023: $1.34BQ3 2023: $797.2MQ4 2023: $1.54BQ1 2024: $2.70BQ2 2024: $2.01BQ3 2024: $3.27BQ4 2024: $2.89BQ1 2025: $2.00BQ2 2025: $3.44BQ3 2025: $4.58BQ4 2025: $6.99BQ1 2026: $8.01BQ2 2026: $11.1B
Institutions holding KYMR and their total value by quarter
QuarterHoldersValue
Q2 2026276$11.1B
Q1 2026256$8.01B
Q4 2025255$6.99B
Q3 2025210$4.58B
Q2 2025210$3.44B
Q1 2025174$2.00B
Q4 2024181$2.89B
Q3 2024176$3.27B
Q2 2024157$2.01B
Q1 2024164$2.70B
Q4 2023137$1.54B
Q3 2023122$797.2M
Q2 2023129$1.34B
Q1 2023127$1.68B
Q4 2022121$1.40B
Q3 2022128$1.15B
Q2 2022101$973.6M
Q1 2022126$1.93B
Q4 2021128$2.76B
Q3 2021115$2.04B
Q2 2021110$1.29B
Q1 202197$887.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Kymera Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding KYMR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
HighVista Strategies LLC6,835$531.8K0.14%−8,893−56.5%Reduced
Scientech Research LLC7,379$574.2K0.36%+7,379New
Vident Advisory, LLC7,581$589.9K0.01%+465+6.5%Added
HSBC Holdings PLC7,619$596.6K0.00%−2,695−26.1%Reduced
BNP Paribas Arbitrage, SA8,798$684.6K0.00%−1,849−17.4%Reduced
Aigen Investment Management, LP9,098$707.9K0.16%−2,779−23.4%Reduced
AQR Capital Management LLC9,339$726.7K0.00%+719+8.3%Added
Odyssean, LLC9,347$727.3K0.52%+9,347New
Legato Capital Management LLC9,534$741.8K0.06%+2,751+40.6%Added
KLP Kapitalforvaltning AS10,200$793.7K0.00%+1,200+13.3%Added
Guggenheim Capital LLC10,307$802.0K0.01%+10,307New
Citigroup Inc10,507$817.5K0.00%+3,601+52.1%Added
Proficio Capital Partners LLC10,845$843.8K0.06%+3,845+54.9%Added
Clough Capital Partners L P10,925$850.1K0.08%+10,925New
Millennium Management LLC11,243$874.8K0.00%−83,718−88.2%Reduced
DekaBank Deutsche Girozentrale23,562$878.0K0.00%00.0%Unchanged
Campbell & CO Investment Adviser LLC11,534$897.5K0.04%+6,963+152.3%Added
Kennedy Capital Management, Inc.12,523$974.4K0.02%+3,041+32.1%Added
State Board of Administration of Florida Retirement System12,655$984.7K0.00%+410+3.3%Added
Knights of Columbus Asset Advisors LLC12,890$1.00M0.06%−6,001−31.8%Reduced
Teachers Retirement System of the State of Kentucky13,026$1.01M0.01%−4,881−27.3%Reduced
SEI Investments Co13,256$1.03M0.00%−1,990−13.1%Reduced
Arizona State Retirement System13,284$1.03M0.01%+853+6.9%Added
ProShare Advisors LLC13,489$1.05M0.00%+2,320+20.8%Added
Susquehanna Portfolio Strategies, LLC13,768$1.07M0.02%00.0%Unchanged
Creative Planning13,769$1.07M0.00%+8,742+173.9%Added
Maven Securities LTD15,000$1.17M0.15%+15,000New
Police & Firemen's Retirement System of New Jersey15,030$1.17M0.01%+1,092+7.8%Added
B. Metzler seel. Sohn & Co. AG15,607$1.21M0.01%+15,607New
Zurcher Kantonalbank (Zurich Cantonalbank)15,631$1.22M0.00%+789+5.3%Added
Norges Bank16,543$1.29M0.00%+16,543New
Handelsbanken Fonder AB18,000$1.40M0.00%−3,700−17.1%Reduced
HRT Financial LP18,173$1.41M0.00%+18,173New
Fred Alger Management, LLC18,639$1.45M0.01%+18,639New
Walleye Capital LLC19,181$1.49M0.01%+19,181New
AJU IB Investment Co., Ltd.19,648$1.53M8.20%−437,411−95.7%Reduced
Bamco Inc20,000$1.56M0.00%+13,000+185.7%Added
Man Group plc20,026$1.56M0.00%+20,026New
Janus Henderson Group PLC21,058$1.64M0.00%+2,750+15.0%Added
Intech Investment Management LLC21,514$1.67M0.01%+6,803+46.2%Added
Profund Advisors LLC22,240$1.73M0.05%+7,227+48.1%Added
SG Americas Securities, LLC22,693$1.77M0.00%+14,261+169.1%Added
XTX Topco Ltd24,143$1.88M0.05%+24,143New
China Universal Asset Management Co., Ltd.24,524$1.91M0.15%+1,992+8.8%Added
Trexquant Investment LP24,680$1.92M0.02%−48,244−66.2%Reduced
Rockefeller Capital Management L.P.25,533$1.99M0.00%+25,415+21,538.1%Added
New York State Common Retirement Fund25,596$1.99M0.00%+1,200+4.9%Added
State of Wisconsin Investment Board26,513$2.06M0.00%−1,259−4.5%Reduced
Virtu Financial LLC27,283$2.12M0.08%+27,283New
Erste Asset Management GmbH27,000$2.17M0.02%00.0%Unchanged
Voya Investment Management LLC28,940$2.25M0.00%−7,515−20.6%Reduced
Seven Grand Managers, LLC30,000$2.33M0.18%+30,000New
Harbor Capital Advisors, Inc.30,573$2.38M0.18%+645+2.2%Added
Nan Fung Group Holdings Ltd30,875$2.40M2.15%00.0%Unchanged
MetLife Investment Management31,394$2.44M0.01%+1,895+6.4%Added
Sio Capital Management, LLC32,235$2.51M0.42%+32,235New
State of New Jersey Common Pension Fund D33,538$2.61M0.01%+33,538New
Silverarc Capital Management, LLC34,589$2.69M0.39%+34,589New
Y-Intercept (Hong Kong) Ltd36,429$2.83M0.06%+36,429New
Marshall Wace, LLP38,022$2.96M0.00%−321,054−89.4%Reduced
Moody Aldrich Partners LLC38,535$3.00M0.56%+9,625+33.3%Added
Dark Forest Capital Management LP39,207$3.05M0.14%+8,155+26.3%Added
Mirae Asset Global ETFs Holdings Ltd.40,777$3.17M0.00%+13,859+51.5%Added
Legal & General Group Plc43,428$3.38M0.00%−69−0.2%Reduced
California State Teachers Retirement System45,742$3.56M0.00%+5,043+12.4%Added
Russell Investments Group, Ltd.45,977$3.58M0.00%+26,986+142.1%Added
Comerica Bank49,812$3.88M0.02%−1,611−3.1%Reduced
Schroder Investment Management Group52,671$4.11M0.00%−8,969−14.6%Reduced
Verition Fund Management LLC54,319$4.23M0.02%+22,848+72.6%Added
Nicholas Investment Partners, LP55,788$4.34M0.32%+3,163+6.0%Added
EAM Investors, LLC56,455$4.39M0.49%−1,130−2.0%Reduced
Neuberger Berman Group LLC58,482$4.55M0.00%+58,482New
Rafferty Asset Management, LLC58,653$4.56M0.02%−9,642−14.1%Reduced
First Trust Advisors LP58,862$4.58M0.00%−15,990−21.4%Reduced
Alps Advisors Inc64,723$5.04M0.03%+64,723New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.64,775$5.04M0.01%+64,363+15,622.1%Added
Wells Fargo & Company66,489$5.17M0.00%+34,428+107.4%Added
Victory Capital Management Inc67,086$5.22M0.00%+35,797+114.4%Added
Perceptive Advisors LLC69,935$5.44M0.10%−99,861−58.8%Reduced
Rhumbline Advisers72,304$5.63M0.00%−1,869−2.5%Reduced
Yiheng Capital Management, L.P.73,440$5.71M2.49%−49,165−40.1%Reduced
Burkehill Global Management, LP75,000$5.84M0.38%00.0%Unchanged
Deutsche Bank AG79,843$6.21M0.00%+7,106+9.8%Added
Armistice Capital, LLC81,165$6.32M0.15%+81,165New
Swiss National Bank94,200$7.33M0.00%+12,600+15.4%Added
Ensign Peak Advisors, Inc95,047$7.40M0.01%+3,150+3.4%Added
Monashee Investment Management LLC100,000$7.78M4.38%+100,000New
Universal- Beteiligungs- und Servicegesellschaft mbH105,554$8.21M0.01%−2,149−2.0%Reduced
WCM Investment Management, LLC105,194$8.22M0.02%+105,194New
Invesco Ltd.116,747$9.08M0.00%+36,940+46.3%Added
Nuveen, LLC125,050$9.73M0.00%+18,345+17.2%Added
Logos Global Management LP130,000$10.1M0.67%−120,000−48.0%Reduced
JPMorgan Chase & Co131,353$10.2M0.00%−61,346−31.8%Reduced
Eagle Health Investments LP136,300$10.6M2.33%+136,300New
Manufacturers Life Insurance Company, The135,894$10.6M0.01%+9,404+7.4%Added
Patient Square Capital LP139,000$10.8M2.32%+46,408+50.1%Added
Barclays PLC140,507$10.9M0.00%−14,637−9.4%Reduced
Foresite Capital Management VI LLC146,332$11.4M3.44%00.0%Unchanged
Squarepoint Ops LLC159,426$12.4M0.03%−191,820−54.6%Reduced
Citadel Advisors LLC159,865$12.4M0.01%+118,042+282.2%Added