| Mar 11, 2024 (view filing) | Mar 8 | 3 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $318.34 | −$1.59M | −10.5%42.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2024 (view filing) | Feb 8 | 4 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $316.13 | −$1.58M | −10.8%41.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 9, 2024 (view filing) | Jan 8 | 1 day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $316.81 | −$4.75M | −28.0%38.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 12, 2023 (view filing) | Dec 8 | 4 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $202.37 | −$2.02M | −21.7%36.1K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2023 (view filing) | Nov 8 | 5 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $177.85 | −$889.3K | −12.9%33.6K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 10, 2023 (view filing) | Oct 9 | 1 day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $173.24 | −$866.2K | −13.8%31.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 11, 2023 (view filing) | Sep 8 | 3 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $184.04 | −$920.2K | −14.9%28.6K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 5, 2023 (view filing) | Sep 1 | 4 days | Jonas Jeffrey MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.8K | $187.93 | −$2.60M | −93.3%990 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 24, 2023 (view filing) | Aug 22 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50K | $175.12 | −$262.7K | −4.7%30.5K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 10, 2023 (view filing) | Aug 8 | 2 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $180.40 | −$902.0K | −16.1%26.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 2, 2023 (view filing) | Aug 1 | 1 day | Jonas Jeffrey MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.8K | $195.81 | −$2.70M | −93.3%990 after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 5, 2023 (view filing) | Jul 3 | 2 days | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $215.65 | −$215.7K | −50.3%990 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 5, 2023 (view filing) | Jul 3 | 2 days | Jonas Jeffrey MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.8K | $216.42 | −$2.99M | −93.3%990 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 25, 2023 (view filing) | May 23 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.00K | $223.41 | −$2.01M | −22.8%30.5K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 20, 2023 (view filing) | Apr 18-20 | 2 days | Miller Andrew CraigChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −45.0K | $200.15 | −$9.01M | −64.8%24.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 12, 2023 (view filing) | Apr 10 | 2 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $176.88 | −$884.4K | −17.5%23.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 5, 2023 (view filing) | Apr 3 | 2 days | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $181.02 | −$181.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 9, 2023 (view filing) | Mar 9 | Same day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $189.51 | −$947.5K | −17.5%23.6K after | |
| Feb 23, 2023 (view filing) | Feb 21 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.00K | $190.01 | −$1.14M | −16.4%30.5K after | |
| Feb 13, 2023 (view filing) | Feb 9 | 4 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $192.37 | −$961.9K | −25.0%15.0K after | |
| Jan 19, 2023 (view filing) | Jan 17-18 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.02K | $201.16 | −$204.6K | −4.4%21.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 17, 2023 (view filing) | Jan 13 | 4 days | Healy JamesDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.03K | $199.90 | −$1.20M | −100.0%0 after | |
| Jan 9, 2023 (view filing) | Jan 9 | Same day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $197.52 | −$987.6K | −25.0%15.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 5, 2023 (view filing) | Jan 3 | 2 days | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $197.48 | −$197.5K | −100.0%0 after | |
| Dec 12, 2022 (view filing) | Dec 9 | 3 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $200.76 | −$1.00M | −25.0%15.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 2, 2022 (view filing) | Dec 1 | 1 day | Miller Andrew CraigChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $228.30 | −$3.42M | −57.1%11.3K after | |
| Nov 17, 2022 (view filing) | Nov 15 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.5K | $225.85 | −$3.73M | −62.3%9.97K after | |
| Nov 14, 2022 (view filing) | Nov 10 | 4 days | Miller Andrew CraigChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $225.98 | −$3.39M | −37.0%25.5K after | |
| Nov 10, 2022 (view filing) | Nov 9 | 1 day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $216.00 | −$1.08M | −25.0%15.0K after | |
| Nov 3, 2022 (view filing) | Nov 1 | 2 days | Miller Andrew CraigChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $225.08 | −$3.38M | −28.0%38.5K after | |
| Oct 12, 2022 (view filing) | Oct 11 | 1 day | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $205.63 | −$205.6K | −100.0%0 after | |
| Oct 12, 2022 (view filing) | Oct 10 | 2 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $207.51 | −$1.04M | −25.0%15.0K after | |
| Oct 4, 2022 (view filing) | Sep 30-Oct 4 | 4 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $229.61 | −$3.44M | −60.1%9.97K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 12, 2022 (view filing) | Sep 9 | 3 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $243.46 | −$1.22M | −25.0%15.0K after | |
| Aug 16, 2022 (view filing) | Aug 15 | 1 day | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $267.59 | −$267.6K | −100.0%0 after | From originalReported on the original filing 0001593968-22-001343. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's. |
| Aug 11, 2022 (view filing) | Aug 9 | 2 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $228.08 | −$5.70M | −62.5%15.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 11, 2022 (view filing) | Aug 9 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.5K | $227.83 | −$3.76M | −39.8%25.0K after | |
| Jul 11, 2022 (view filing) | Jul 11 | Same day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $133.29 | −$2.00M | −50.0%15.0K after | |
| Jul 1, 2022 (view filing) | Jun 29-30 | 2 days | Healy JamesDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +120.0K | $122.80 | +$14.7M | +6.1%2.07M after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 9, 2022 (view filing) | Jun 9 | Same day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $110.90 | −$554.5K | −25.0%15.0K after | |
| May 31, 2022 (view filing) | May 27 | 4 days | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $110.00 | −$110.0K | −100.0%0 after | |
| May 9, 2022 (view filing) | May 9 | Same day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $104.10 | −$520.5K | −25.0%15.0K after | |
| Apr 21, 2022 (view filing) | Apr 19-21 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.24K | $131.24 | −$557.0K | −14.5%25.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 14, 2022 (view filing) | Apr 1 | 13 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Healy JamesDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +47 | $129.38 | +$6.08K | +7.4%683 after | |
| Apr 4, 2022 (view filing) | Apr 1 | 3 days | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.73K | $128.45 | −$992.7K | −34.0%15.0K after | |
| Mar 2, 2022 (view filing) | Mar 1 | 1 day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.73K | $107.38 | −$829.8K | −38.2%12.5K after | |
| Feb 17, 2022 (view filing) | Feb 15 | 2 days | Ignelzi Troy A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50K | $111.14 | −$166.7K | −5.7%25.0K after | |
| Feb 17, 2022 (view filing) | Feb 15 | 2 days | Olson Laurie JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $110.00 | −$110.0K | −100.0%0 after | |
| Feb 2, 2022 (view filing) | Feb 1 | 1 day | Brannan Stephen K.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.73K | $110.05 | −$850.5K | −43.6%10.0K after | |
| Feb 2, 2022 (view filing) | Feb 1 | 1 day | Pande AtulDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.50K | $110.80 | −$277.0K | −100.0%0 after | |
