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Ironwood Pharmaceuticals Inc

IRWD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001446847

In the last 90 days, Ironwood Pharmaceuticals Inc insiders filed 0 open-market purchases and 1 sale; 212 institutions reported holding it in 13F filings for Q2 2026, worth $675.8M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Ironwood Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
199
+38 vs. Q3 2025
Shares held
154.6M
+6.08M (+4.1%) vs. Q3 2025
Total value
$520.2M
+$325.4M (+167.1%) vs. Q3 2025
New holders
56
64 more added
Sold out
18
47 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IRWD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 199 institutions
Q1 2021: 210 institutionsQ2 2021: 209 institutionsQ3 2021: 229 institutionsQ4 2021: 212 institutionsQ1 2022: 221 institutionsQ2 2022: 240 institutionsQ3 2022: 245 institutionsQ4 2022: 250 institutionsQ1 2023: 255 institutionsQ2 2023: 252 institutionsQ3 2023: 249 institutionsQ4 2023: 251 institutionsQ1 2024: 261 institutionsQ2 2024: 227 institutionsQ3 2024: 221 institutionsQ4 2024: 223 institutionsQ1 2025: 200 institutionsQ2 2025: 155 institutionsQ3 2025: 166 institutionsQ4 2025: 199 institutionsQ1 2026: 227 institutionsQ2 2026: 212 institutions
Value heldQ4 2025: $520.2M
Q1 2021: $1.91BQ2 2021: $2.25BQ3 2021: $2.32BQ4 2021: $2.00BQ1 2022: $2.09BQ2 2022: $2.02BQ3 2022: $1.76BQ4 2022: $2.08BQ1 2023: $1.74BQ2 2023: $1.77BQ3 2023: $1.56BQ4 2023: $1.89BQ1 2024: $1.50BQ2 2024: $1.12BQ3 2024: $673.7MQ4 2024: $727.5MQ1 2025: $228.5MQ2 2025: $104.9MQ3 2025: $194.9MQ4 2025: $520.2MQ1 2026: $566.8MQ2 2026: $675.8M
Institutions holding IRWD and their total value by quarter
QuarterHoldersValue
Q2 2026212$675.8M
Q1 2026227$566.8M
Q4 2025199$520.2M
Q3 2025166$194.9M
Q2 2025155$104.9M
Q1 2025200$228.5M
Q4 2024223$727.5M
Q3 2024221$673.7M
Q2 2024227$1.12B
Q1 2024261$1.50B
Q4 2023251$1.89B
Q3 2023249$1.56B
Q2 2023252$1.77B
Q1 2023255$1.74B
Q4 2022250$2.08B
Q3 2022245$1.76B
Q2 2022240$2.02B
Q1 2022221$2.09B
Q4 2021212$2.00B
Q3 2021229$2.32B
Q2 2021209$2.25B
Q1 2021210$1.91B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Ironwood Pharmaceuticals Inc; share changes are against Q3 2025.

Institutions holding IRWD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Armistice Capital, LLC16,025,000$54.0M1.32%−125,000−0.8%Reduced
Vanguard Group Inc15,958,196$53.8M0.00%−113,810−0.7%Reduced
Sarissa Capital Management LP15,919,435$53.6M24.07%00.0%Unchanged
BlackRock, Inc.12,784,806$43.1M0.00%+722,248+6.0%Added
Bank of America Corp11,521,660$38.8M0.00%−173,884−1.5%Reduced
Renaissance Technologies LLC8,204,973$27.7M0.04%−147,200−1.8%Reduced
Acadian Asset Management LLC6,457,817$21.7M0.04%−44,676−0.7%Reduced
Charles Schwab Investment Management Inc4,975,939$16.8M0.00%+58,603+1.2%Added
AQR Capital Management LLC4,723,531$15.9M0.01%−655,004−12.2%Reduced
Marshall Wace, LLP4,424,002$14.9M0.01%+1,279,863+40.7%Added
State Street Corp4,411,222$14.9M0.00%+1,254,915+39.8%Added
Geode Capital Management, LLC3,623,534$12.2M0.00%+8,547+0.2%Added
Federated Hermes, Inc.3,318,137$11.2M0.02%+1,161,033+53.8%Added
Two Sigma Advisers, LP3,140,100$10.6M0.02%−176,400−5.3%Reduced
Two Sigma Investments, LP2,853,205$9.62M0.01%+318,694+12.6%Added
Jane Street Group, LLC2,819,562$9.50M0.01%+498,467+21.5%Added
Jacobs Levy Equity Management, Inc2,759,667$9.30M0.04%+839,137+43.7%Added
Connor, Clark & Lunn Investment Management Ltd.1,990,927$6.71M0.02%−170,891−7.9%Reduced
Qube Research & Technologies Ltd1,681,229$5.67M0.01%−1,125,681−40.1%Reduced
Goldman Sachs Group Inc1,275,315$4.30M0.00%+190,948+17.6%Added
Northern Trust Corp1,233,685$4.16M0.00%−107,221−8.0%Reduced
Hillsdale Investment Management Inc.1,156,378$3.90M0.11%+1,156,378New
Deutsche Bank AG1,109,924$3.74M0.00%−417,305−27.3%Reduced
Lazard Asset Management LLC1,000,445$3.37M0.01%+1,000,445New
Raymond James Financial Inc869,826$2.93M0.00%+854,780+5,681.1%Added
Morgan Stanley739,685$2.49M0.00%+262,585+55.0%Added
FMR LLC686,737$2.31M0.00%+126,791+22.6%Added
Diadema Partners LP683,611$2.30M1.37%+683,611New
SEI Investments Co673,862$2.27M0.00%−9,742−1.4%Reduced
Exome Asset Management LLC648,532$2.19M1.08%+648,532New
Amundi642,830$2.17M0.00%+642,830New
Ieq Capital, LLC633,260$2.13M0.01%−28,438−4.3%Reduced
Gsa Capital Partners LLP571,613$1.93M0.17%+262,084+84.7%Added
Millennium Management LLC560,713$1.89M0.00%+310,594+124.2%Added
Walleye Capital LLC527,936$1.78M0.01%+527,936New
UBS Group AG510,543$1.72M0.00%−301,121−37.1%Reduced
Bank of New York Mellon Corp510,207$1.72M0.00%+7,129+1.4%Added
Wellington Management Group LLP503,942$1.70M0.00%+503,942New
Bridgeway Capital Management, LLC495,993$1.67M0.04%+345,993+230.7%Added
Invesco Ltd.449,219$1.51M0.00%+82,687+22.6%Added
Susquehanna International Group, LLP448,799$1.51M0.00%+351,933+363.3%Added
Range Financial Group LLC426,095$1.44M0.50%+426,095New
Arrowstreet Capital, Limited Partnership412,061$1.39M0.00%+412,061New
Barclays PLC392,904$1.32M0.00%+95,586+32.1%Added
Franklin Resources Inc385,583$1.30M0.00%+362,332+1,558.4%Added
Robeco Institutional Asset Management B.V.342,998$1.16M0.00%00.0%Unchanged
Cerity Partners LLC338,512$1.14M0.00%−536−0.2%Reduced
Dimensional Fund Advisors LP330,836$1.11M0.00%+240,463+266.1%Added
O'Shaughnessy Asset Management, LLC290,278$978.2K0.01%+290,278New
Los Angeles Capital Management LLC634,331$951.5K0.00%−495,721−43.9%Reduced
Russell Investments Group, Ltd.265,357$893.7K0.00%−61,210−18.7%Reduced
CWM, LLC232,984$785.0K0.00%+194+0.1%Added
Citadel Advisors LLC223,969$754.8K0.00%−420,077−65.2%Reduced
Omers Administration Corp215,110$724.9K0.01%00.0%Unchanged
JPMorgan Chase & Co214,607$723.2K0.00%+102,450+91.3%Added
Rhumbline Advisers199,908$673.7K0.00%−23,321−10.4%Reduced
Alliancebernstein L.P.199,520$672.4K0.00%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC155,523$664.9K0.00%+1,135+0.7%Added
Hennion & Walsh Asset Management, Inc.196,032$660.6K0.02%+26,539+15.7%Added
Canada Pension Plan Investment Board188,000$633.6K0.00%+188,000New
Persistent Asset Partners Ltd182,046$613.5K0.29%+182,046New
State of Wisconsin Investment Board180,040$606.7K0.00%+180,040New
Wells Fargo & Company176,582$595.1K0.00%+75,330+74.4%Added
KLP Kapitalforvaltning AS174,200$587.1K0.00%00.0%Unchanged
Winton Group Ltd164,335$553.8K0.02%+164,335New
Creative Planning162,075$546.2K0.00%+71,919+79.8%Added
State of Wyoming157,325$530.2K0.06%−205,082−56.6%Reduced
Prudential Financial Inc141,129$475.6K0.00%+91,194+182.6%Added
Nuveen, LLC139,487$470.1K0.00%+139,487New
Prelude Capital Management, LLC136,507$460.0K0.03%+136,507New
Ameriprise Financial Inc119,969$404.3K0.00%00.0%Unchanged
Quantinno Capital Management LP118,893$400.7K0.00%+118,893New
D. E. Shaw & Co., Inc.117,446$395.8K0.00%−254,824−68.5%Reduced
Mariner, LLC114,119$384.2K0.00%+12,806+12.6%Added
Integrated Quantitative Investments LLC102,654$345.9K0.07%+102,654New
Cercano Management LLC101,378$341.6K0.01%00.0%Unchanged
Price T Rowe Associates Inc99,363$335.0K0.00%+19,185+23.9%Added
Squarepoint Ops LLC88,880$299.5K0.00%+68,613+338.5%Added
Pallas Capital Advisors LLC87,975$296.5K0.01%+406+0.5%Added
MetLife Investment Management87,521$294.9K0.00%+29,512+50.9%Added
Universal- Beteiligungs- und Servicegesellschaft mbH79,013$266.3K0.00%−45,862−36.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.78,103$263.1K0.00%+5,132+7.0%Added
Mercer Global Advisors Inc76,951$259.3K0.00%+5,598+7.8%Added
STRS Ohio76,600$258.1K0.00%00.0%Unchanged
Exchange Traded Concepts, LLC76,554$258.0K0.00%−119,178−60.9%Reduced
SmartHarvest Portfolios, LLC75,585$254.7K0.09%+75,585New
JustInvest LLC74,839$252.2K0.00%+2,133+2.9%Added
Virtus Investment Advisers, Inc.74,311$250.4K0.07%+74,311New
Intech Investment Management LLC71,573$241.2K0.00%−621−0.9%Reduced
CIBC World Markets Inc.71,331$240.4K0.00%+71,331New
Public Employees Retirement System of Ohio67,888$228.8K0.00%+7,120+11.7%Added
Scotia Capital Inc.67,183$226.4K0.00%+67,183New
EntryPoint Capital, LLC66,625$224.5K0.09%+66,625New
Balyasny Asset Management LLC65,156$219.6K0.00%+65,156New
Rafferty Asset Management, LLC64,841$218.5K0.00%+64,841New
Captrust Financial Advisors63,822$215.1K0.00%+668+1.1%Added
Wedbush Securities Inc63,733$215.0K0.01%+63,733New
Optimist Retirement Group LLC59,912$201.9K0.09%+59,912New
Buckingham Strategic Partners59,617$200.9K0.00%+7,322+14.0%Added
Virtus ETF Advisers LLC58,000$195.5K0.09%+58,000New