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Disc Medicine, Inc.

IRON
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001816736

In the last 90 days, Disc Medicine, Inc. insiders filed 0 open-market purchases and 9 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $3.13B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Disc Medicine, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
197
+31 vs. Q3 2025
Shares held
38.3M
+4.08M (+11.9%) vs. Q3 2025
Total value
$3.04B
+$779.8M (+34.5%) vs. Q3 2025
New holders
42
86 more added
Sold out
11
48 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IRON on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 197 institutions
Q1 2021: 49 institutionsQ2 2021: 55 institutionsQ3 2021: 62 institutionsQ4 2021: 62 institutionsQ1 2022: 57 institutionsQ2 2022: 51 institutionsQ3 2022: 44 institutionsQ4 2022: 35 institutionsQ1 2023: 45 institutionsQ2 2023: 90 institutionsQ3 2023: 91 institutionsQ4 2023: 112 institutionsQ1 2024: 130 institutionsQ2 2024: 121 institutionsQ3 2024: 132 institutionsQ4 2024: 152 institutionsQ1 2025: 157 institutionsQ2 2025: 152 institutionsQ3 2025: 168 institutionsQ4 2025: 197 institutionsQ1 2026: 203 institutionsQ2 2026: 216 institutions
Value heldQ4 2025: $3.04B
Q1 2021: $346.6MQ2 2021: $165.3MQ3 2021: $103.5MQ4 2021: $93.8MQ1 2022: $39.6MQ2 2022: $43.8MQ3 2022: $43.9MQ4 2022: $215.8MQ1 2023: $309.6MQ2 2023: $848.7MQ3 2023: $934.0MQ4 2023: $1.17BQ1 2024: $1.38BQ2 2024: $1.24BQ3 2024: $1.35BQ4 2024: $1.68BQ1 2025: $1.65BQ2 2025: $1.80BQ3 2025: $2.26BQ4 2025: $3.04BQ1 2026: $2.67BQ2 2026: $3.13B
Institutions holding IRON and their total value by quarter
QuarterHoldersValue
Q2 2026216$3.13B
Q1 2026203$2.67B
Q4 2025197$3.04B
Q3 2025168$2.26B
Q2 2025152$1.80B
Q1 2025157$1.65B
Q4 2024152$1.68B
Q3 2024132$1.35B
Q2 2024121$1.24B
Q1 2024130$1.38B
Q4 2023112$1.17B
Q3 202391$934.0M
Q2 202390$848.7M
Q1 202345$309.6M
Q4 202235$215.8M
Q3 202244$43.9M
Q2 202251$43.8M
Q1 202257$39.6M
Q4 202162$93.8M
Q3 202162$103.5M
Q2 202155$165.3M
Q1 202149$346.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Disc Medicine, Inc.; share changes are against Q3 2025.

Institutions holding IRON in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Deutsche Bank AG20,523$1.63M0.00%+1,637+8.7%Added
Campbell & CO Investment Adviser LLC17,399$1.38M0.07%+12,109+228.9%Added
State of Wisconsin Investment Board17,106$1.36M0.00%+4,733+38.3%Added
Teachers Retirement System of the State of Kentucky16,156$1.28M0.01%+3,305+25.7%Added
Squarepoint Ops LLC15,754$1.25M0.00%+10,377+193.0%Added
AQR Capital Management LLC14,007$1.11M0.00%+29+0.2%Added
New York State Common Retirement Fund13,985$1.11M0.00%−7,505−34.9%Reduced
Prelude Capital Management, LLC13,985$1.11M0.08%−4,171−23.0%Reduced
MetLife Investment Management13,832$1.10M0.01%−90−0.6%Reduced
Mirae Asset Global ETFs Holdings Ltd.13,711$1.08M0.00%+1,065+8.4%Added
Profund Advisors LLC13,478$1.07M0.03%+5,360+66.0%Added
Voya Investment Management LLC13,186$1.05M0.00%+8,920+209.1%Added
Fred Alger Management, LLC12,267$974.1K0.00%−1,459−10.6%Reduced
Janus Henderson Group PLC11,555$918.0K0.00%−350,149−96.8%Reduced
Y-Intercept (Hong Kong) Ltd11,359$902.0K0.02%−31,928−73.8%Reduced
PFM Health Sciences, LP11,002$873.7K0.09%−21,537−66.2%Reduced
Ghisallo Capital Management LLC10,000$794.1K0.04%+10,000New
Intech Investment Management LLC9,910$787.0K0.01%+1,904+23.8%Added
Kennedy Capital Management, Inc.9,324$740.4K0.02%+296+3.3%Added
Susquehanna International Group, LLP9,309$739.2K0.00%−23,308−71.5%Reduced
State Board of Administration of Florida Retirement System8,704$691.2K0.00%−425−4.7%Reduced
State of New Jersey Common Pension Fund D8,306$659.6K0.00%+8,306New
Legato Capital Management LLC8,248$655.0K0.06%−3,039−26.9%Reduced
Lion Point Capital, LP8,100$643.2K3.33%−2,500−23.6%Reduced
Arrowstreet Capital, Limited Partnership7,767$616.8K0.00%+7,767New
China Universal Asset Management Co., Ltd.7,751$615.5K0.05%+657+9.3%Added
Jain Global LLC7,319$581.2K0.01%+7,319New
Los Angeles Capital Management LLC6,494$556.9K0.00%+6,494New
FORA Capital, LLC6,735$543.9K0.07%+6,735New
Arizona State Retirement System6,798$539.8K0.00%+144+2.2%Added
Police & Firemen's Retirement System of New Jersey6,716$533.3K0.00%+215+3.3%Added
ProShare Advisors LLC6,227$494.5K0.00%+1,039+20.0%Added
STRS Ohio6,000$476.5K0.00%+3,800+172.7%Added
Engineers Gate Manager LP5,460$433.6K0.01%+5,460New
VARCOV Co.5,327$423.0K0.17%+5,327New
KLP Kapitalforvaltning AS5,200$412.9K0.00%+600+13.0%Added
Marshall Wace, LLP4,642$368.6K0.00%−9,359−66.8%Reduced
Abel Hall, LLC4,443$352.8K0.08%+4,443New
Entropy Technologies, LP4,357$346.0K0.02%+4,357New
Fiduciary Trust Co4,051$321.7K0.00%00.0%Unchanged
Creative Planning3,864$306.8K0.00%+3,864New
AlphaCentric Advisors LLC3,756$298.3K0.30%+3,756New
Susquehanna Portfolio Strategies, LLC3,733$296.4K0.00%00.0%Unchanged
Teacher Retirement System of Texas3,614$287.0K0.00%−1,873−34.1%Reduced
Gsa Capital Partners LLP3,287$261.0K0.02%+3,287New
Allianz Asset Management GmbH3,000$238.2K0.00%+3,000New
Zurcher Kantonalbank (Zurich Cantonalbank)2,988$237.3K0.00%00.0%Unchanged
Virtus Investment Advisers, Inc.2,897$230.1K0.06%+739+34.2%Added
Saxon Interests, Inc.2,576$204.6K0.07%+2,576New
Ameritas Investment Partners, Inc.2,059$163.5K0.00%+128+6.6%Added
Avanza Fonder AB1,903$151.1K0.00%+235+14.1%Added
Mirae Asset Global Investments Co., Ltd.1,834$145.6K0.00%+490+36.5%Added
Persistent Asset Partners Ltd1,780$141.3K0.07%+1,780New
US Bancorp1,176$93.4K0.00%00.0%Unchanged
CWM, LLC1,033$82.0K0.00%+6+0.6%Added
KBC Group NV1,011$80.0K0.00%+1,011New
Royal Bank of Canada802$64.0K0.00%−15,894−95.2%Reduced
Amalgamated Bank784$62.0K0.00%−3−0.4%Reduced
Tower Research Capital LLC (TRC)776$61.6K0.00%−329−29.8%Reduced
GF Fund Management Co. Ltd.742$58.9K0.00%−6−0.8%Reduced
Public Employees Retirement Association of Colorado730$58.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC528$41.9K0.00%−5−0.9%Reduced
Cygnus Capital Advisors, LLC502$40.0K0.03%+502New
Antipodes Partners Ltd419$33.3K0.00%+419New
Quest Partners LLC366$29.1K0.00%+39+11.9%Added
GAMMA Investing LLC304$24.1K0.00%+28+10.1%Added
Advisor Group Holdings, Inc.273$21.7K0.00%+3+1.1%Added
Nisa Investment Advisors, LLC240$19.1K0.00%−53−18.1%Reduced
Caitong International Asset Management Co., Ltd232$18.4K0.00%+172+286.7%Added
Sterling Capital Management LLC163$12.9K0.00%+107+191.1%Added
Daiwa Securities Group Inc.113$9.00K0.00%00.0%Unchanged
Larson Financial Group LLC112$8.89K0.00%+4+3.7%Added
Smartleaf Asset Management LLC73$5.61K0.00%+73New
Optiver Holding B.V.70$5.56K0.00%−124−63.9%Reduced
Kemnay Advisory Services Inc.69$5.48K0.00%+69New
EverSource Wealth Advisors, LLC67$5.32K0.00%−8−10.7%Reduced
J.Safra Asset Management Corp63$5.00K0.00%+57+950.0%Added
Farther Finance Advisors, LLC53$4.21K0.00%+46+657.1%Added
Rothschild Investment LLC40$3.18K0.00%00.0%Unchanged
First Horizon Corp28$2.22K0.00%+28New
Parkside Financial Bank & Trust20$1.59K0.00%00.0%Unchanged
Comerica Bank19$1.54K0.00%−25−56.8%Reduced
Versant Capital Management, Inc19$1.51K0.00%00.0%Unchanged
Assetmark, Inc12$9530.00%00.0%Unchanged
Cornerstone Financial Management LLC11$8740.00%+11New
Bare Financial Services, Inc9$7150.00%00.0%Unchanged
Allworth Financial LP7$5560.00%+1+16.7%Added
Essential Partners LLC4$3180.00%00.0%Unchanged
Global Retirement Partners, LLC3$2380.00%−3−50.0%Reduced
IFP Advisors, Inc3$2380.00%00.0%Unchanged
SRS Capital Advisors, Inc.2$1590.00%−204−99.0%Reduced
True Wealth Design, LLC1$800.00%00.0%Unchanged
SBI Securities Co., Ltd.1$790.00%−5−83.3%Reduced
Hughes Financial Services, LLC1$790.00%+1New
Basecamp Wealth Advisors LLC1$790.00%+1New
Bessemer Group Inc2$00.00%00.0%Unchanged
Covestor Ltd2$00.00%00.0%Unchanged
TCG Crossover Management, LLC0$00.00%−465,257−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−450,000−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−247,716−100.0%Sold out