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Hyperion Defi, Inc.

HYPD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001682639

No open-market purchases or sales by Hyperion Defi, Inc. insiders were filed in the last 90 days; 33 institutions reported holding it in 13F filings for Q2 2026, worth $7.92M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Hyperion Defi, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
30
+9 vs. Q3 2025
Shares held
1.14M
+655.1K (+136.4%) vs. Q3 2025
Total value
$4.18M
−$418.1K (−9.1%) vs. Q3 2025
New holders
11
5 more added
Sold out
2
5 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HYPD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 30 institutions
Q1 2021: 28 institutionsQ2 2021: 26 institutionsQ3 2021: 26 institutionsQ4 2021: 28 institutionsQ1 2022: 28 institutionsQ2 2022: 31 institutionsQ3 2022: 30 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 50 institutionsQ3 2023: 44 institutionsQ4 2023: 52 institutionsQ1 2024: 56 institutionsQ2 2024: 61 institutionsQ3 2024: 50 institutionsQ4 2024: 39 institutionsQ1 2025: 18 institutionsQ2 2025: 18 institutionsQ3 2025: 23 institutionsQ4 2025: 30 institutionsQ1 2026: 30 institutionsQ2 2026: 33 institutions
Value heldQ4 2025: $4.18M
Q1 2021: $10.7MQ2 2021: $9.28MQ3 2021: $9.44MQ4 2021: $7.86MQ1 2022: $12.5MQ2 2022: $7.51MQ3 2022: $4.25MQ4 2022: $4.83MQ1 2023: $12.9MQ2 2023: $15.2MQ3 2023: $16.2MQ4 2023: $23.8MQ1 2024: $7.86MQ2 2024: $7.01MQ3 2024: $6.91MQ4 2024: $808.6KQ1 2025: $306.0KQ2 2025: $1.45MQ3 2025: $7.04MQ4 2025: $4.18MQ1 2026: $4.62MQ2 2026: $7.92M
Institutions holding HYPD and their total value by quarter
QuarterHoldersValue
Q2 202633$7.92M
Q1 202630$4.62M
Q4 202530$4.18M
Q3 202523$7.04M
Q2 202518$1.45M
Q1 202518$306.0K
Q4 202439$808.6K
Q3 202450$6.91M
Q2 202461$7.01M
Q1 202456$7.86M
Q4 202352$23.8M
Q3 202344$16.2M
Q2 202350$15.2M
Q1 202329$12.9M
Q4 202227$4.83M
Q3 202230$4.25M
Q2 202231$7.51M
Q1 202228$12.5M
Q4 202128$7.86M
Q3 202126$9.44M
Q2 202126$9.28M
Q1 202128$10.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Hyperion Defi, Inc.; share changes are against Q3 2025.

Institutions holding HYPD in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Renaissance Technologies LLC186,100$662.5K0.00%+186,100New
Redwood Wealth Management Group, LLC179,583$639.3K0.27%+90,803+102.3%Added
Jane Street Group, LLC138,421$492.8K0.00%+138,421New
UBS Group AG89,464$318.5K0.00%+89,242+40,199.1%Added
Vanguard Group Inc86,060$306.4K0.00%00.0%Unchanged
BlackRock, Inc.78,108$278.1K0.00%00.0%Unchanged
Formidable Asset Management, LLC23,380$224.0K0.03%+23,380New
Buckingham Strategic Partners62,183$221.4K0.00%+62,183New
Keb Asset Management, LLC62,183$221.4K0.04%+62,183New
Geode Capital Management, LLC60,194$214.3K0.00%+6,774+12.7%Added
Investment House LLC46,675$166.2K0.01%+35,950+335.2%Added
State Street Corp25,857$92.1K0.00%00.0%Unchanged
Price T Rowe Associates Inc20,500$73.0K0.00%+20,500New
Northern Trust Corp18,731$66.7K0.00%+5,320+39.7%Added
Citadel Advisors LLC17,025$60.6K0.00%+17,025New
Nations Financial Group Inc,11,125$39.6K0.00%+11,125New
Sanctuary Advisors, LLC10,800$38.4K0.00%+10,800New
Bank of America Corp10,053$35.8K0.00%−26,926−72.8%Reduced
Larson Financial Group LLC4,283$15.2K0.00%00.0%Unchanged
SBI Securities Co., Ltd.2,025$7.21K0.00%−3,330−62.2%Reduced
Royal Bank of Canada1,004$4.00K0.00%+1,004New
Abound Financial, LLC890$3.17K0.00%+890New
Morgan Stanley419$1.49K0.00%−43,614−99.0%Reduced
Farther Finance Advisors, LLC105$3740.00%00.0%Unchanged
10Elms LLP90$3200.00%00.0%Unchanged
Tower Research Capital LLC (TRC)65$2310.00%−12,448−99.5%Reduced
BNP Paribas Arbitrage, SA54$1920.00%00.0%Unchanged
Wells Fargo & Company30$1070.00%−43−58.9%Reduced
JPMorgan Chase & Co8$280.00%00.0%Unchanged
Group One Trading, L.P.1$40.00%00.0%Unchanged
Cetera Investment Advisers0$00.00%−10,225−100.0%Sold out
GTS Securities LLC0$00.00%−10,000−100.0%Sold out
Lasry Marc––––Not filed
Cubist Systematic Strategies, LLC––––Not filed