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Humacyte, Inc.

HUMA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001818382

In the last 90 days, Humacyte, Inc. insiders filed 3 open-market purchases and 0 sales; 164 institutions reported holding it in 13F filings for Q2 2026, worth $57.3M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Humacyte, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
147
+8 vs. Q3 2025
Shares held
55.3M
+9.53M (+20.8%) vs. Q3 2025
Total value
$53.1M
−$26.6M (−33.3%) vs. Q3 2025
New holders
23
55 more added
Sold out
15
35 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HUMA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 147 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 32 institutionsQ4 2021: 61 institutionsQ1 2022: 70 institutionsQ2 2022: 78 institutionsQ3 2022: 70 institutionsQ4 2022: 75 institutionsQ1 2023: 69 institutionsQ2 2023: 75 institutionsQ3 2023: 83 institutionsQ4 2023: 88 institutionsQ1 2024: 95 institutionsQ2 2024: 123 institutionsQ3 2024: 143 institutionsQ4 2024: 162 institutionsQ1 2025: 168 institutionsQ2 2025: 156 institutionsQ3 2025: 141 institutionsQ4 2025: 147 institutionsQ1 2026: 159 institutionsQ2 2026: 164 institutions
Value heldQ4 2025: $53.1M
Q1 2021: $0Q2 2021: $0Q3 2021: $77.5MQ4 2021: $69.0MQ1 2022: $74.0MQ2 2022: $43.1MQ3 2022: $38.6MQ4 2022: $25.1MQ1 2023: $37.4MQ2 2023: $42.2MQ3 2023: $48.7MQ4 2023: $50.7MQ1 2024: $72.4MQ2 2024: $149.8MQ3 2024: $194.7MQ4 2024: $212.7MQ1 2025: $104.1MQ2 2025: $118.9MQ3 2025: $79.8MQ4 2025: $53.1MQ1 2026: $35.9MQ2 2026: $57.3M
Institutions holding HUMA and their total value by quarter
QuarterHoldersValue
Q2 2026164$57.3M
Q1 2026159$35.9M
Q4 2025147$53.1M
Q3 2025141$79.8M
Q2 2025156$118.9M
Q1 2025168$104.1M
Q4 2024162$212.7M
Q3 2024143$194.7M
Q2 2024123$149.8M
Q1 202495$72.4M
Q4 202388$50.7M
Q3 202383$48.7M
Q2 202375$42.2M
Q1 202369$37.4M
Q4 202275$25.1M
Q3 202270$38.6M
Q2 202278$43.1M
Q1 202270$74.0M
Q4 202161$69.0M
Q3 202132$77.5M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Humacyte, Inc.; share changes are against Q3 2025.

Institutions holding HUMA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Mirae Asset Global ETFs Holdings Ltd.72,022$69.2K0.00%+13,161+22.4%Added
Kovack Advisors, Inc.72,600$69.7K0.00%+72,600New
JPMorgan Chase & Co75,782$72.8K0.00%+11,620+18.1%Added
Price T Rowe Associates Inc76,017$73.0K0.00%+13,175+21.0%Added
Engineers Gate Manager LP84,955$81.6K0.00%+84,955New
Endowment Wealth Management, Inc.105,913$96.8K0.04%−3,545−3.2%Reduced
Deutsche Bank AG108,752$104.4K0.00%+7,666+7.6%Added
Voleon Capital Management LP135,830$130.5K0.00%+135,830New
Two Sigma Advisers, LP144,100$138.4K0.00%−99,000−40.7%Reduced
Alliancebernstein L.P.145,560$139.8K0.00%00.0%Unchanged
Wealth Effects LLC153,067$147.0K0.05%−54,950−26.4%Reduced
Shay Capital LLC160,900$154.5K0.02%+160,900New
Aristides Capital LLC162,900$156.5K0.05%+162,900New
Wells Fargo & Company174,470$167.6K0.00%+76,449+78.0%Added
Rhumbline Advisers178,165$171.2K0.00%+2,686+1.5%Added
Quadrature Capital Ltd208,959$200.7K0.00%+208,959New
United Asset Strategies, Inc.209,608$201.3K0.02%+25,000+13.5%Added
Bridgeway Capital Management, LLC210,000$201.7K0.00%+35,000+20.0%Added
Nuveen, LLC261,489$251.2K0.00%00.0%Unchanged
Virtu Financial LLC262,725$252.0K0.01%+262,725New
Group One Trading, L.P.264,597$254.1K0.01%+125,124+89.7%Added
LJI Wealth Management, LLC308,500$296.3K0.05%−7,500−2.4%Reduced
Bank of New York Mellon Corp343,751$330.2K0.00%+21,395+6.6%Added
Goldman Sachs Group Inc427,238$410.4K0.00%−62,021−12.7%Reduced
Bank of America Corp452,208$434.1K0.00%−28,801−6.0%Reduced
Squarepoint Ops LLC458,178$440.1K0.00%+458,178New
Marshall Wace, LLP488,369$468.8K0.00%−330,585−40.4%Reduced
Lion Point Capital, LP500,000$480.3K2.49%+416,500+498.8%Added
Jane Street Group, LLC518,918$498.4K0.00%+423,216+442.2%Added
Private Advisor Group, LLC561,577$539.4K0.00%−467,503−45.4%Reduced
XTX Topco Ltd650,858$625.1K0.02%+457,236+236.1%Added
Barclays PLC729,469$700.7K0.00%+546,491+298.7%Added
LPL Financial LLC837,661$804.6K0.00%+46,904+5.9%Added
Susquehanna International Group, LLP1,009,670$969.8K0.00%−133,363−11.7%Reduced
BNP Paribas Arbitrage, SA1,100,837$1.06M0.00%+1,009,097+1,100.0%Added
Northern Trust Corp1,146,910$1.10M0.00%+115,454+11.2%Added
Charles Schwab Investment Management Inc1,239,477$1.19M0.00%+227,560+22.5%Added
Two Sigma Investments, LP1,491,467$1.43M0.00%+124,883+9.1%Added
Citadel Advisors LLC1,566,431$1.50M0.00%+673,479+75.4%Added
Woodline Partners LP2,002,073$1.92M0.01%00.0%Unchanged
Morgan Stanley2,505,428$2.41M0.00%+408,675+19.5%Added
Millennium Management LLC2,631,990$2.53M0.00%+1,485,152+129.5%Added
State Street Corp2,837,276$2.73M0.00%+429,233+17.8%Added
UBS Group AG2,978,610$2.86M0.00%+976,275+48.8%Added
Geode Capital Management, LLC3,720,436$3.57M0.00%+624,220+20.2%Added
Vanguard Group Inc8,416,971$8.09M0.00%+896,916+11.9%Added
BlackRock, Inc.11,345,119$10.9M0.00%+1,443,324+14.6%Added
CenterBook Partners LP0$00.00%−283,627−100.0%Sold out
Integrated Advisors Network LLC0$00.00%−86,782−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−80,394−100.0%Sold out
Quinn Opportunity Partners LLC0$00.00%−65,000−100.0%Sold out
Truist Financial Corp0$00.00%−16,282−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−26,211−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−23,729−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−14,891−100.0%Sold out
Prudential Financial Inc0$00.00%−13,320−100.0%Sold out
Whittier Trust Co of Nevada Inc0$00.00%−10,000−100.0%Sold out
Byrne Asset Management LLC0$00.00%−5,000−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−528−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−351−100.0%Sold out
Essential Partners LLC0$00.00%−267−100.0%Sold out
Allworth Financial LP0$00.00%−205−100.0%Sold out
Wolverine Trading, LLC––––Not filed
CIBC Bancorp USA Inc.––––Not filed