| Nov 10, 2026 (view filing)6:59 PM ET | Nov 10 | Same day | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −38.9K | $55.74 | −$2.17M | −13.4%252.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 10, 2026 (view filing)6:52 PM ET | Nov 9 | 1 day | Verghese VikramChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock. | −3.59K | $53.15 | −$190.6K | −2.3%149.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 26, 2026 (view filing)6:00 PM ET | Oct 22 | 4 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −23.9K | $55.01 | −$1.32M | −24.6%73.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 14, 2026 (view filing)6:05 PM ET | Oct 12 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −38.9K | $49.57 | −$1.93M | −12.1%283.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 21, 2026 (view filing)6:19 PM ET | Sep 18 | 3 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.7K | $50.15 | −$987.1K | −19.8%80.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 18, 2026 (view filing)8:46 PM ET | Sep 17-18 | 1 day | Verghese VikramChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock. | −24.3K | $50.55 | −$1.23M | −13.6%155.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 15, 2026 (view filing)7:44 PM ET | Sep 11-15 | 4 days | Verghese VikramChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock. | −35.0K | $50.08 | −$1.75M | −16.3%179.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 14, 2026 (view filing)6:41 PM ET | Sep 10-11 | 4 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −38.9K | $46.78 | −$1.82M | −10.8%321.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 10, 2026 (view filing)5:24 PM ET | Sep 8 | 2 days | Verghese VikramChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock. | −6.64K | $50.03 | −$332.2K | −3.0%214.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2026 (view filing)5:29 PM ET | Sep 2-3 | 2 days | Verghese VikramChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock. | −33.4K | $49.85 | −$1.67M | −13.1%221.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 25, 2026 (view filing)5:32 PM ET | Aug 21 | 4 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.2K | $50.00 | −$1.36M | −7.0%360.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 20, 2026 (view filing)5:56 PM ET | Aug 18 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.7K | $45.00 | −$1.47M | −7.8%388.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 19, 2026 (view filing)9:04 PM ET | Aug 17 | 2 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.22K | $41.23 | −$380.1K | −9.6%86.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 18, 2026 (view filing)6:38 PM ET | Aug 14 | 4 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.6K | $39.06 | −$607.8K | −3.6%420.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 12, 2026 (view filing)5:07 PM ET | Aug 10 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $28.31 | −$638.7K | −4.9%436.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 17, 2026 (view filing)5:54 PM ET | Jul 15 | 2 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.22K | $25.72 | −$237.1K | −9.4%88.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 13, 2026 (view filing)8:25 PM ET | Jul 10 | 3 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $27.75 | −$626.1K | −4.9%435.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 26, 2026 (view filing) | Jun 24 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −38.9K | $35.00 | −$1.36M | −7.8%457.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 12, 2026 (view filing) | Jun 10 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $28.50 | −$643.0K | −4.3%496.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 20, 2026 (view filing) | May 18 | 2 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.22K | $28.34 | −$261.3K | −10.5%78.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 13, 2026 (view filing) | May 11 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $29.12 | −$657.0K | −4.2%519.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 30, 2026 (view filing)8:46 PM ET | Apr 28-30 | 2 days | Bain Capital Life Sciences Investors, LLC and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00M | $29.45 | −$58.9M | −19.1%8.45M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 14, 2026 (view filing) | Apr 10 | 4 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $26.72 | −$602.9K | −3.9%549.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 3, 2026 (view filing) | Apr 1 | 2 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −64.5K | $24.64 | −$1.59M | −44.3%81.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 23, 2026 (view filing) | Mar 19 | 4 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −64.5K | $25.69 | −$1.66M | −45.1%78.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 20, 2026 (view filing) | Mar 18 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.72K | $25.00 | −$243.1K | −1.7%571.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 12, 2026 (view filing) | Mar 10 | 2 days | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.8K | $22.66 | −$290.9K | −2.2%581.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 6, 2026 (view filing) | Mar 5 | 1 day | Cullivan Julie ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.12K | $25.00 | −$228.1K | −25.1%27.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 17, 2026 (view filing) | Feb 12 | 5 days | Rogers CampbellChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −65.2K | $24.49 | −$1.60M | −46.1%76.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 10, 2026 (view filing) | Feb 10 | Same day | Farquhar John C.M.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.6K | $27.46 | −$619.6K | −3.7%591.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 6, 2026 (view filing)4:58 PM ET | Feb 4 | 2 days | Bain Capital Life Sciences Investors, LLC and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00M | $28.05 | −$56.1M | −16.1%10.4M after | |
| Feb 6, 2026 (view filing) | Feb 5 | 1 day | Cullivan Julie ADirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $27.32 | −$218.6K | −18.0%36.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 17, 2025 (view filing) | Dec 16 | 1 day | Lightcap Jeffrey CDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +40.0K | $26.34 | +$1.05M | New position40.0K after | |
