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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

No open-market purchases or sales by Fulcrum Therapeutics, Inc. insiders were filed in the last 90 days; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

Currency
USD
Source
SEC XBRL data (10-K, 10-Q, 20-F, 40-F)
Updated
Oct 8, 2026, 1:56 PM ET

Income statement

Each column is one fiscal year, newest first.

Income statement of Fulcrum Therapeutics, Inc., annual
Line itemFY2025FY2024FY2023FY2022FY2021
Period endDec 31, 2025Dec 31, 2024Dec 31, 2023Dec 31, 2022Dec 31, 2021
Filing10-K10-K10-K10-K/A10-K/A
ReportedJan 12, 2026Jan 13, 2025Feb 27, 2024Jan 4, 2023Jan 10, 2022
Revenue$0$80.0M$2.81M$6.34M$19.2M
Operating expenses$84.8M$101.9M$113.5M$118.9M$100.2M
Research and development$56.1M$63.4M$71.8M$76.8M$69.7M
Selling, general and administrative$28.7M$36.4M$41.7M$41.7M$30.5M
Operating income-$84.8M-$21.9M-$110.7M-$112.6M-$81.1M
Income tax$0––––
Net income-$74.9M-$9.72M-$97.3M-$109.9M-$80.8M
EPS, basic$-1.18$-0.16$-1.59$-2.44$-2.29
EPS, diluted$-1.18$-0.16$-1.59$-2.44$-2.29
Weighted shares, basic63.4K62.0K61.3K45.0K35.4K
Weighted shares, diluted63.4K62.0K61.3K45.0K35.4K
Margins and growth
Operating margin–-27.4%-3945.2%-1774.9%-423.0%
Net margin–-12.2%-3470.1%-1732.4%-421.9%
Revenue growth, year over year−100.0%+2,752.0%−55.8%−66.9%+117.2%

Balance sheet

Each column is one fiscal year, newest first.

Balance sheet of Fulcrum Therapeutics, Inc., annual
Line itemFY2025FY2024FY2023FY2022FY2021
Period endDec 31, 2025Dec 31, 2024Dec 31, 2023Dec 31, 2022Dec 31, 2021
Filing10-K10-K10-K10-K/A10-K/A
ReportedJan 12, 2026Jan 13, 2025Feb 27, 2024Jan 4, 2023Jan 10, 2022
Cash and equivalents$197.5M$58.2M$25.6M$35.1M$35.4M
Total current assets$357.5M$249.9M$242.2M$207.5M$226.0M
Property, plant and equipment$2.82M$3.90M$5.22M$6.91M$7.37M
Total assets$366.3M$260.7M$257.7M$226.7M$235.0M
Accounts payable$1.59M$1.16M$2.76M$3.64M$4.79M
Total current liabilities$13.0M$11.0M$13.7M$16.7M$19.2M
Total liabilities$17.3M$17.7M$22.5M$27.7M$23.5M
Shareholders' equity$349.0M$243.0M$235.2M$198.9M$211.5M

Cash flow statement

Each column is one fiscal year, newest first. Free cash flow is operating cash flow minus capital expenditures.

Cash flow statement of Fulcrum Therapeutics, Inc., annual
Line itemFY2025FY2024FY2023FY2022FY2021
Period endDec 31, 2025Dec 31, 2024Dec 31, 2023Dec 31, 2022Dec 31, 2021
Filing10-K10-K10-K10-K/A10-K/A
ReportedJan 12, 2026Jan 13, 2025Feb 27, 2024Jan 4, 2023Jan 10, 2022
Operating cash flow-$60.1M-$2.22M-$91.0M-$97.0M-$78.5M
Capital expenditures$314.0K$278.0K$508.0K$1.96M$1.71M
Free cash flow-$60.4M-$2.50M-$91.5M-$99.0M-$80.2M
Stock-based compensation$12.5M$14.6M$14.8M$13.3M$11.1M
Investing cash flow$30.7M$32.2M-$36.7M$12.4M-$129.7M
Financing cash flow$168.7M$2.75M$118.1M$84.3M$186.5M
Net change in cash$139.3M$32.8M-$9.54M-$314.0K-$21.6M
Ratio
Stock-based compensation, % of revenue–18.2%527.7%210.5%57.8%

Shares outstanding

Common shares outstanding as stated on the cover of each 10-K and 10-Q. The date is the cover date, not the period end; a rising count means dilution.

Shares outstanding for Fulcrum Therapeutics, Inc. by cover date
Cover dateShares outstandingChange in a yearFiling
Jul 23, 202676.3M+41.1%SEC
Apr 20, 202666.6M+23.4%SEC
Feb 17, 202666.6M+23.4%SEC
Oct 22, 202554.1M+0.3%SEC
Jul 22, 202554.1M−13.3%SEC
Apr 24, 202554.0M−13.2%SEC
Feb 18, 202554.0M−12.8%SEC
Nov 6, 202453.9M−12.8%SEC

Notes and known gaps

How these numbers are put together, and what they can't tell you.

  • Numbers come from the XBRL data in each period's original 10-K, 10-Q, 20-F or 40-F, or its amendment. They are shown as filed: later filings don't restate earlier periods here.
  • Reported is the filing date of the first 8-K with Item 2.02 (results of operations) after the period ended, no later than the 10-Q or 10-K and within 120 days. Companies that release results only in the 10-Q, and foreign companies, which use Form 6-K, have none.

Known gaps

  • Foreign companies that file Form 20-F or 40-F have annual statements only: their quarterly results are furnished on Form 6-K, which has no XBRL data.
  • EPS and share counts are as reported at the time, not adjusted for later stock splits.
  • For ADRs, EPS is per ordinary share, not per ADS (one TSMC ADS is five ordinary shares).
  • For banks, revenue may be interest income only, depending on how the bank tags its filings; cost of revenue and gross profit are usually blank.
  • Companies with several share classes, such as Berkshire Hathaway, may have no EPS and no cover share count.
  • Depreciation and amortization is missing for some companies that report it under their own XBRL tags.