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4D Molecular Therapeutics, Inc.

FDMT
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001650648

In the last 90 days, 4D Molecular Therapeutics, Inc. insiders filed 0 open-market purchases and 9 sales; 157 institutions reported holding it in 13F filings for Q2 2026, worth $771.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in 4D Molecular Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
153
+20 vs. Q3 2025
Shares held
53.4M
+13.9M (+35.1%) vs. Q3 2025
Total value
$400.5M
+$57.4M (+16.7%) vs. Q3 2025
New holders
32
56 more added
Sold out
12
37 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FDMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 153 institutions
Q1 2021: 64 institutionsQ2 2021: 56 institutionsQ3 2021: 63 institutionsQ4 2021: 77 institutionsQ1 2022: 80 institutionsQ2 2022: 90 institutionsQ3 2022: 88 institutionsQ4 2022: 96 institutionsQ1 2023: 94 institutionsQ2 2023: 100 institutionsQ3 2023: 110 institutionsQ4 2023: 111 institutionsQ1 2024: 147 institutionsQ2 2024: 143 institutionsQ3 2024: 140 institutionsQ4 2024: 146 institutionsQ1 2025: 126 institutionsQ2 2025: 121 institutionsQ3 2025: 134 institutionsQ4 2025: 153 institutionsQ1 2026: 153 institutionsQ2 2026: 157 institutions
Value heldQ4 2025: $400.5M
Q1 2021: $664.8MQ2 2021: $400.0MQ3 2021: $515.1MQ4 2021: $541.8MQ1 2022: $395.3MQ2 2022: $181.7MQ3 2022: $210.4MQ4 2022: $621.9MQ1 2023: $522.3MQ2 2023: $745.3MQ3 2023: $533.6MQ4 2023: $859.8MQ1 2024: $1.79BQ2 2024: $1.20BQ3 2024: $629.2MQ4 2024: $260.6MQ1 2025: $139.8MQ2 2025: $149.9MQ3 2025: $343.2MQ4 2025: $400.5MQ1 2026: $471.4MQ2 2026: $771.2M
Institutions holding FDMT and their total value by quarter
QuarterHoldersValue
Q2 2026157$771.2M
Q1 2026153$471.4M
Q4 2025153$400.5M
Q3 2025134$343.2M
Q2 2025121$149.9M
Q1 2025126$139.8M
Q4 2024146$260.6M
Q3 2024140$629.2M
Q2 2024143$1.20B
Q1 2024147$1.79B
Q4 2023111$859.8M
Q3 2023110$533.6M
Q2 2023100$745.3M
Q1 202394$522.3M
Q4 202296$621.9M
Q3 202288$210.4M
Q2 202290$181.7M
Q1 202280$395.3M
Q4 202177$541.8M
Q3 202163$515.1M
Q2 202156$400.0M
Q1 202164$664.8M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding 4D Molecular Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding FDMT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Squarepoint Ops LLC71,721$537.9K0.00%+24,884+53.1%Added
Engineers Gate Manager LP74,269$557.0K0.01%+74,269New
Rafferty Asset Management, LLC83,413$625.6K0.00%+83,413New
American Century Companies Inc91,084$683.1K0.00%+21,465+30.8%Added
Millennium Management LLC96,364$722.7K0.00%−1,053,037−91.6%Reduced
Silverarc Capital Management, LLC100,000$750.0K0.11%+100,000New
D. E. Shaw & Co., Inc.111,822$838.7K0.00%+101,722+1,007.1%Added
ADAR1 Capital Management, LLC116,712$875.3K0.07%+100,000+598.4%Added
Susquehanna International Group, LLP126,013$945.1K0.00%−6,799−5.1%Reduced
Wellington Management Group LLP130,252$976.9K0.00%−5,218−3.9%Reduced
Bank of New York Mellon Corp136,739$1.03M0.00%−4,977−3.5%Reduced
Perigon Wealth Management, LLC146,133$1.10M0.02%00.0%Unchanged
Invesco Ltd.153,142$1.15M0.00%+26,563+21.0%Added
Nuveen, LLC158,769$1.19M0.00%+64,850+69.0%Added
Schonfeld Strategic Advisors LLC161,982$1.21M0.01%−17,093−9.5%Reduced
Barclays PLC170,639$1.28M0.00%+76,811+81.9%Added
Woodline Partners LP200,001$1.50M0.01%+200,001New
Privium Fund Management B.V.210,000$1.57M0.29%+12,542+6.4%Added
Jane Street Group, LLC224,903$1.69M0.00%+107,988+92.4%Added
UBS Group AG231,292$1.73M0.00%+136,392+143.7%Added
Peapod Lane Capital LLC268,024$2.01M1.71%−54,057−16.8%Reduced
Burkehill Global Management, LP275,000$2.06M0.14%+275,000New
Two Sigma Advisers, LP275,300$2.06M0.00%−274,400−49.9%Reduced
JPMorgan Chase & Co279,505$2.10M0.00%−234,010−45.6%Reduced
Dimensional Fund Advisors LP294,841$2.21M0.00%+236,835+408.3%Added
Assenagon Asset Management S.A.296,199$2.22M0.00%−367,458−55.4%Reduced
Northern Trust Corp313,820$2.35M0.00%−21,766−6.5%Reduced
Two Sigma Investments, LP337,503$2.53M0.00%+64,007+23.4%Added
Charles Schwab Investment Management Inc353,391$2.65M0.00%+47,534+15.5%Added
Baker Bros. Advisors LP475,737$3.57M0.02%+475,737New
RTW Investments, LP475,737$3.57M0.04%+475,737New
Raymond James Financial Inc477,505$3.58M0.00%+6,235+1.3%Added
ArrowMark Colorado Holdings LLC485,389$3.64M0.08%−18,726−3.7%Reduced
Parkman Healthcare Partners LLC503,431$3.78M0.36%+303,431+151.7%Added
Renaissance Technologies LLC512,900$3.85M0.01%+199,714+63.8%Added
Morgan Stanley672,695$5.05M0.00%−163,216−19.5%Reduced
Deutsche Bank AG704,207$5.28M0.00%+160,876+29.6%Added
Bank of America Corp832,591$6.24M0.00%+13,325+1.6%Added
Evergreen Quality Fund GP, Ltd.951,474$7.14M0.14%+951,474New
Geode Capital Management, LLC1,012,025$7.59M0.00%+98,506+10.8%Added
Adage Capital Partners GP, L.L.C.1,235,156$9.26M0.01%+1,060,156+605.8%Added
Point72 Asset Management, L.P.1,539,860$11.5M0.02%+1,539,860New
Federated Hermes, Inc.1,609,482$12.1M0.02%+14,650+0.9%Added
Armistice Capital, LLC1,936,000$14.5M0.36%+840,000+76.6%Added
State Street Corp2,688,880$20.2M0.00%+1,785,106+197.5%Added
Vanguard Group Inc3,093,527$23.2M0.00%+518,405+20.1%Added
Novo Holdings A/S3,650,737$27.4M2.13%+1,650,737+82.5%Added
BlackRock, Inc.4,064,876$30.5M0.00%+195,746+5.1%Added
Goldman Sachs Group Inc4,302,905$32.3M0.00%+174,489+4.2%Added
BVF Inc4,629,289$34.7M1.17%00.0%Unchanged
Janus Henderson Group PLC4,635,875$34.7M0.02%+2,882,508+164.4%Added
Ra Capital Management, L.P.5,653,211$42.4M0.43%+1,090,000+23.9%Added
DekaBank Deutsche Girozentrale30,000––00.0%Unchanged
HSBC Holdings PLC0$00.00%−48,806−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−22,917−100.0%Sold out
Proficio Capital Partners LLC0$00.00%−20,121−100.0%Sold out
Zuckerman Investment Group, LLC0$00.00%−20,000−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−16,400−100.0%Sold out
Wexford Capital LP0$00.00%−4,676−100.0%Sold out
Simplex Trading, LLC0$00.00%−2,925−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−1,500−100.0%Sold out
Allworth Financial LP0$00.00%−393−100.0%Sold out
US Bancorp0$00.00%−57−100.0%Sold out
Advisory Services Network, LLC0$00.00%−8−100.0%Sold out
Summit Wealth Group LLC0$00.00%−13,204−100.0%Sold out
Abich Financial Wealth Management LLC––––Not filed