| Jul 2, 2021 (view filing) | Jul 1 | 1 day | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −55.5K | $85.24 | −$4.73M | −33.9%108.0K after | From originalReported on the original filing 0001209191-21-045182. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.11 lotsThis row combines 11 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 26, 2021 (view filing) | Jul 22-23 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −60.0K | $85.66 | −$5.14M | −13.2%393.8K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 20, 2021 (view filing) | Aug 19 | 1 day | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.47K | $88.26 | −$306.6K | −6.0%54.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 20, 2021 (view filing) | Aug 19 | 1 day | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $88.01 | −$1.76M | −4.8%393.8K after | |
| Sep 14, 2021 (view filing) | Sep 13 | 1 day | Valamehr BahramChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $66.29 | −$1.66M | −20.7%95.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 30, 2021 (view filing) | Sep 28 | 2 days | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.5K | $62.53 | −$1.22M | −27.1%52.4K after | |
| Oct 4, 2021 (view filing) | Oct 1 | 3 days | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −50.0K | $58.83 | −$2.94M | −31.6%108.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 25, 2021 (view filing) | Oct 21-22 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −60.0K | $59.55 | −$3.57M | −13.2%393.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 22, 2021 (view filing) | Nov 18 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $54.27 | −$1.09M | −4.8%393.8K after | |
| Dec 13, 2021 (view filing) | Dec 10 | 3 days | Chu Yu-WayeSenior VP Clinical Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.50K | $51.46 | −$385.9K | −5.6%125.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 14, 2021 (view filing) | Dec 13 | 1 day | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $47.66 | −$1.19M | −13.8%156.7K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 21, 2021 (view filing) | Dec 20 | 1 day | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.0K | $60.00 | −$958.6K | −12.6%110.4K after | |
| Jan 4, 2022 (view filing) | Jan 3 | 1 day | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −50.0K | $59.34 | −$2.97M | −22.8%169.0K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 12, 2022 (view filing) | Jan 10 | 2 days | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.60K | $46.38 | −$259.6K | −3.6%151.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 12, 2022 (view filing) | Jan 10 | 2 days | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.74K | $46.43 | −$359.3K | −4.6%161.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 12, 2022 (view filing) | Jan 10 | 2 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.2K | $46.86 | −$1.60M | −7.1%446.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Chu Yu-WayeSenior VP Clinical Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.96K | $48.51 | −$192.3K | −3.2%121.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.77K | $48.45 | −$85.8K | −1.6%108.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.57K | $48.50 | −$221.7K | −3.0%146.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.42K | $48.53 | −$263.0K | −3.4%155.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.6K | $48.68 | −$709.0K | −3.3%431.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 24, 2022 (view filing) | Jan 20-21 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −40.0K | $39.66 | −$1.59M | −8.5%431.5K after | From originalReported on the original filing 0001209191-22-004606. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 11, 2022 (view filing) | Mar 10 | 1 day | Mendlein JohnDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.6K | $35.02 | −$1.11M | −16.5%159.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 15, 2022 (view filing) | Mar 14 | 1 day | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $31.07 | −$776.7K | −12.2%179.8K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 4, 2022 (view filing) | Apr 1 | 3 days | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $38.85 | −$971.3K | −11.7%189.2K after | |
| Apr 21, 2022 (view filing) | Apr 19 | 2 days | Chu Yu-WayeChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.06K | $35.37 | −$143.7K | −2.6%151.0K after | |
| Apr 25, 2022 (view filing) | Apr 21-22 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −40.0K | $34.89 | −$1.40M | −8.5%431.5K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 2, 2022 (view filing) | Jun 1 | 1 day | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $22.96 | −$574.0K | −11.7%189.2K after | |
| Jun 6, 2022 (view filing) | Jun 3 | 3 days | Coughlin TimothyDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.44K | $22.81 | −$32.8K | −2.4%57.6K after | |
| Jun 6, 2022 (view filing) | Jun 3 | 3 days | Hershberg RobertDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −672 | $22.75 | −$15.3K | −25.1%2.01K after | |
| Jun 6, 2022 (view filing) | Jun 3 | 3 days | Jooss KarinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.48K | $22.82 | −$33.8K | −55.3%1.20K after | |
| Jun 6, 2022 (view filing) | Jun 3 | 3 days | Mendlein JohnDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.36K | $22.79 | −$31.1K | −0.9%158.1K after | |
| Jun 8, 2022 (view filing) | Jun 3 | 5 days | Agarwal ShefaliDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | 0 | – | $0 | 0.0%2.68K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jun 8, 2022 (view filing) | Jun 7 | 1 day | Agarwal ShefaliDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −841 | $21.89 | −$18.4K | −31.4%1.84K after | |
| Jul 6, 2022 (view filing) | Jul 5 | 1 day | Plavsic MarkChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.72K | $24.61 | −$91.5K | −2.8%127.1K after | |
| Jul 7, 2022 (view filing) | Jul 6 | 1 day | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.84K | $30.07 | −$235.8K | −4.2%179.8K after | |
| Jul 8, 2022 (view filing) | Jul 7 | 1 day | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.2K | $30.23 | −$518.7K | −8.7%179.8K after | |
| Jul 25, 2022 (view filing) | Jul 21-22 | 4 days | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −36.2K | $32.74 | −$1.19M | −7.7%431.5K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 19, 2022 (view filing) | Aug 18 | 1 day | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.13K | $29.81 | −$153.1K | −3.6%136.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Chu Yu-WayeChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.83K | $5.24 | −$41.0K | −5.2%143.2K after | |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Dulac Edward J IIIChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.33K | $5.24 | −$38.4K | −5.4%129.5K after | |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Plavsic MarkChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.42K | $5.24 | −$17.9K | −2.7%123.7K after | |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Tahl CindyGeneral Counsel and Secretary | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.6K | $5.24 | −$60.5K | −6.1%177.6K after | |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Valamehr BahramChief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.9K | $5.24 | −$57.2K | −6.1%168.9K after | |
| Jan 11, 2023 (view filing) | Jan 10 | 1 day | Wolchko J ScottPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −45.9K | $5.24 | −$240.6K | −10.6%385.6K after | |
| Jan 13, 2023 (view filing) | Jan 11-13 | 2 days | Mendlein JohnDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +124.7K | $5.60 | +$698.1K | +78.9%282.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 17, 2023 (view filing)9:30 PM ET | Apr 14 | 3 days | Redmile Group, LLC and 1 otherDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −302.3K | $5.84 | −$1.77M | −2.3%12.8M after | |
| Apr 17, 2023 (view filing)9:30 PM ET | Apr 14 | 3 days | Redmile Group, LLC and 1 otherDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +25.7K | $6.00 | +$154.2K | +0.2%12.9M after | |
| Apr 19, 2023 (view filing) | Apr 18 | 1 day | Chu Yu-WayeChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.53K | $6.57 | −$16.6K | −1.8%140.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 21, 2023 (view filing)9:55 PM ET | Apr 20-21 | 1 day | Redmile Group, LLC and 1 otherDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +276.6K | $6.17 | +$1.71M | +2.2%13.1M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
