| Aug 12, 2026 (view filing)7:34 PM ET | Aug 10 | 2 days | Beckerle Mary CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.81K | $53.66 | −$526.5K | −37.9%16.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2026 (view filing) | Jun 1 | 2 days | Wyszomierski Jack LDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.92K | $50.55 | −$198.4K | −1.4%284.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2026 (view filing) | Jun 1 | 2 days | Eckhardt Sue GailDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.81K | $50.14 | −$492.0K | −37.9%16.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 28, 2026 (view filing) | May 26 | 2 days | Aftab DanaEVP, Research and Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −43.5K | $50.35 | −$2.19M | −6.8%594.7K after | |
| May 22, 2026 (view filing) | May 20 | 2 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.1K | $49.81 | −$1.60M | −8.2%357.6K after | |
| May 19, 2026 (view filing) | May 18 | 1 day | Senner Christopher J.EVP and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.9K | $50.00 | −$1.75M | −3.5%952.3K after | |
| May 19, 2026 (view filing) | May 18 | 1 day | Hefti BrendaSVP and General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.63K | $50.21 | −$332.6K | −5.8%106.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 8, 2026 (view filing) | May 7 | 1 day | Beckerle Mary CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.71K | $48.45 | −$373.6K | −30.6%17.5K after | |
| May 8, 2026 (view filing) | May 7 | 1 day | Freire Maria CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.6K | $46.00 | −$949.2K | −17.0%100.8K after | |
| May 8, 2026 (view filing) | May 7 | 1 day | Poste GeorgeDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −60.0K | $45.71 | −$2.74M | −33.6%118.8K after | |
| Feb 26, 2026 (view filing) | Feb 24 | 2 days | Aftab DanaEVP, Research and Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −47.9K | $44.50 | −$2.13M | −7.2%616.1K after | |
| Feb 23, 2026 (view filing) | Feb 19 | 4 days | Aftab DanaEVP, Research and Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.9K | $44.35 | −$1.32M | −4.3%664.0K after | |
| Feb 20, 2026 (view filing) | Feb 18 | 2 days | Wyszomierski Jack LDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −99.6K | $44.01 | −$4.38M | −26.2%279.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2026 (view filing) | Feb 17-18 | 2 days | Smith JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −106.5K | $44.00 | −$4.69M | −83.8%20.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 18, 2026 (view filing) | Feb 13-17 | 5 days | Senner Christopher J.EVP and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −64.9K | $43.32 | −$2.81M | −6.2%976.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 18, 2026 (view filing) | Feb 17 | 1 day | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −67.8K | $43.52 | −$2.95M | −15.1%381.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Eckhardt Sue GailDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.86K | $43.79 | −$168.9K | −18.0%17.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Oliver BobDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.3K | $43.81 | −$1.33M | −58.9%21.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 18, 2026 (view filing) | Feb 18 | Same day | Hefti BrendaSVP and General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.7K | $44.01 | −$821.6K | −16.2%96.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 26, 2025 (view filing)4:05 PM ET | Nov 25 | 1 day | Caligan Partners LP and 1 otherDirector, Other: See Remarks | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +27.5K | $43.12 | +$1.19M | +1.8%1.55M after | |
| Nov 24, 2025 (view filing) | Nov 20-21 | 4 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −38.0K | $42.46 | −$1.62M | −9.2%374.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 24, 2025 (view filing) | Nov 20 | 4 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.2K | $41.88 | −$1.43M | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 13, 2025 (view filing) | Nov 12 | 1 day | Papadopoulos SteliosDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $43.55 | −$4.36M | −7.8%1.19M after | |
| Nov 13, 2025 (view filing) | Nov 11 | 2 days | Aftab DanaEVP, Research and Development | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −48.4K | $42.50 | −$2.06M | −6.8%664.8K after | |
| Nov 13, 2025 (view filing) | Nov 11 | 2 days | Beckerle Mary CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.6K | $41.93 | −$1.03M | −53.5%21.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 4, 2025 (view filing) | Jun 2 | 2 days | Eckhardt Sue GailDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.8K | $42.74 | −$805.1K | −46.8%21.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 4, 2025 (view filing) | Jun 3 | 1 day | Wyszomierski Jack LDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.54K | $43.09 | −$324.7K | −2.1%358.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 22, 2025 (view filing) | May 20 | 2 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.4K | $44.06 | −$1.52M | −7.7%412.1K after | |
| May 22, 2025 (view filing) | May 21 | 1 day | Heyman Tomas J.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.54K | $44.29 | −$201.3K | −12.3%32.5K after | |
| May 16, 2025 (view filing) | May 16 | Same day | Poste GeorgeDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.6K | $45.99 | −$949.0K | −10.9%169.0K after | |
| May 16, 2025 (view filing) | May 16 | Same day | Senner Christopher J.EVP and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $46.00 | −$4.60M | −9.4%967.8K after | |
| May 16, 2025 (view filing) | May 15 | 1 day | Papadopoulos SteliosDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −36.5K | $44.35 | −$1.62M | −2.8%1.28M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| May 16, 2025 (view filing) | May 15 | 1 day | Hessekiel JeffreyEVP & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $46.18 | −$1.15M | −3.5%693.4K after | |
| May 16, 2025 (view filing) | May 14-15 | 2 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −136.4K | $47.58 | −$6.49M | −23.4%446.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 16, 2025 (view filing) | May 16 | Same day | Peterson Amy C.EVP Prod Dev & Med Aff & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −72.8K | $45.47 | −$3.31M | −13.5%465.4K after | |
| May 5, 2025 (view filing) | May 1 | 4 days | Aftab DanaCSO/EVP Disc & Trans Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.51K | $39.00 | −$58.8K | −0.2%693.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $38.80 | −$388.0K | −2.8%341.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 28, 2025 (view filing) | Feb 27-28 | 1 day | Smith JulieDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −73.8K | $38.00 | −$2.80M | −87.3%10.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 28, 2025 (view filing) | Feb 28 | Same day | Wyszomierski Jack LDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.77K | $37.80 | −$331.4K | −2.4%356.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 26, 2025 (view filing) | Feb 24 | 2 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.6K | $36.98 | −$1.95M | −14.8%303.3K after | |
| Feb 26, 2025 (view filing) | Feb 25 | 1 day | Oliver BobDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.6K | $37.25 | −$694.6K | −35.7%33.5K after | |
| Feb 26, 2025 (view filing) | Feb 24 | 2 days | Aftab DanaCSO/EVP Disc & Trans Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.0K | $36.75 | −$991.8K | −5.0%511.9K after | |
| Feb 26, 2025 (view filing) | Feb 24 | 2 days | Senner Christopher J.EVP and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.3K | $36.14 | −$1.06M | −3.6%779.6K after | |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Beckerle Mary CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.2K | $34.88 | −$425.9K | −28.7%30.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Poste GeorgeDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.9K | $34.74 | −$551.5K | −8.6%169.0K after | |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Freire Maria CDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −44.1K | $34.94 | −$1.54M | −32.6%91.0K after | |
| Feb 19, 2025 (view filing) | Feb 14 | 5 days | Eckhardt Sue GailDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.6K | $35.02 | −$405.1K | −27.6%30.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 2, 2024 (view filing) | Nov 29 | 3 days | Hessekiel JeffreyEVP & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −60.0K | $36.67 | −$2.20M | −11.0%486.1K after | |
| Nov 26, 2024 (view filing) | Nov 22 | 4 days | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $35.27 | −$352.7K | −3.5%278.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 19, 2024 (view filing) | Nov 18 | 1 day | Haley Patrick J.EVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −41.6K | $34.36 | −$1.43M | −12.6%288.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
