Skip to main content

enGene Therapeutics Inc.

ENGN
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001980845

In the last 90 days, enGene Therapeutics Inc. insiders filed 1 open-market purchase and 0 sales; 60 institutions reported holding it in 13F filings for Q2 2026, worth $86.5M in total; no superinvestor holds it.

Other share classesENGNW

13F holders, Q4 2025

Institutional positions in enGene Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
58
+21 vs. Q3 2025
Shares held
58.8M
+17.9M (+43.9%) vs. Q3 2025
Total value
$530.8M
+$251.8M (+90.2%) vs. Q3 2025
New holders
27
17 more added
Sold out
6
8 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ENGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 58 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 11 institutionsQ1 2024: 31 institutionsQ2 2024: 30 institutionsQ3 2024: 30 institutionsQ4 2024: 34 institutionsQ1 2025: 31 institutionsQ2 2025: 36 institutionsQ3 2025: 37 institutionsQ4 2025: 58 institutionsQ1 2026: 62 institutionsQ2 2026: 60 institutions
Value heldQ4 2025: $530.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $130.9MQ1 2024: $536.1MQ2 2024: $307.1MQ3 2024: $227.7MQ4 2024: $274.7MQ1 2025: $183.4MQ2 2025: $147.1MQ3 2025: $279.1MQ4 2025: $530.8MQ1 2026: $383.0MQ2 2026: $86.5M
Institutions holding ENGN and their total value by quarter
QuarterHoldersValue
Q2 202660$86.5M
Q1 202662$383.0M
Q4 202558$530.8M
Q3 202537$279.1M
Q2 202536$147.1M
Q1 202531$183.4M
Q4 202434$274.7M
Q3 202430$227.7M
Q2 202430$307.1M
Q1 202431$536.1M
Q4 202311$130.9M
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding enGene Therapeutics Inc.; share changes are against Q3 2025.

Institutions holding ENGN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FCPM III Services B.V.9,632,561$87.0M11.40%00.0%Unchanged
Perceptive Advisors LLC5,869,076$53.0M0.97%+3,771,840+179.8%Added
VR Adviser, LLC4,771,414$43.1M2.13%−275,000−5.4%Reduced
Deep Track Capital, LP4,377,572$39.5M0.90%+2,138,219+95.5%Added
Cormorant Asset Management, LP4,000,000$36.1M2.05%+1,676,405+72.1%Added
Blue Owl Capital Holdings LP3,360,937$30.3M9.37%+82,831+2.5%Added
Siren, L.L.C.3,336,264$30.1M0.90%+3,336,264New
Braidwell LP3,131,319$28.3M0.90%+865,000+38.2%Added
Nextech Invest, Ltd.2,124,943$19.2M1.85%+2,124,943New
Janus Henderson Group PLC1,900,000$17.1M0.01%+1,900,000New
MPM Oncology Impact Management LP1,840,898$16.6M1.90%+1,310,599+247.1%Added
Millennium Management LLC1,499,520$13.5M0.01%+1,479,018+7,214.0%Added
Kynam Capital Management, LP1,492,898$13.5M0.88%−3,501,192−70.1%Reduced
Franklin Resources Inc1,388,000$12.5M0.00%+350,000+33.7%Added
Polar Capital Holdings Plc1,142,982$10.3M0.05%+1,142,982New
Vestal Point Capital, LP1,055,000$9.53M0.35%+685,000+185.1%Added
Eventide Asset Management, LLC950,000$8.58M0.13%+950,000New
Omega Fund Management, LLC876,357$7.91M2.76%+350,000+66.5%Added
Sr One Capital Management, LP747,750$6.75M0.96%00.0%Unchanged
Morgan Stanley718,485$6.49M0.00%+283,194+65.1%Added
Affinity Asset Advisors, LLC643,370$5.81M0.42%+566,370+735.5%Added
Point72 Asset Management, L.P.561,797$5.07M0.01%−646,602−53.5%Reduced
Eversept Partners, LP455,835$4.12M0.23%+455,835New
Privium Fund Management B.V.352,087$3.18M0.59%+352,087New
Marshall Wace, LLP343,928$3.11M0.00%00.0%Unchanged
ADAR1 Capital Management, LLC303,686$2.74M0.21%+303,686New
Monashee Investment Management LLC295,000$2.66M1.50%+295,000New
Woodline Partners LP250,000$2.26M0.01%+250,000New
Elmind Capital, LP210,000$1.90M0.56%+210,000New
DAFNA Capital Management LLC163,645$1.48M0.34%+163,645New
Two Sigma Investments, LP161,512$1.46M0.00%+161,512New
Goldman Sachs Group Inc147,889$1.34M0.00%+287+0.2%Added
Deeter Investments LLP90,000$812.7K0.18%+90,000New
Kennedy Capital Management, Inc.76,765$693.2K0.01%+76,765New
HRT Financial LP64,380$581.0K0.00%+64,380New
Jane Street Group, LLC56,454$509.8K0.00%+56,454New
Quadrature Capital Ltd48,583$438.7K0.00%+48,583New
BNP Paribas Arbitrage, SA35,877$324.0K0.00%+35,877New
Virtus Investment Advisers, Inc.31,445$283.9K0.08%+31,445New
Northern Trust Corp30,085$271.7K0.00%−210−0.7%Reduced
Geode Capital Management, LLC29,018$262.0K0.00%00.0%Unchanged
Citadel Advisors LLC25,383$229.2K0.00%−32,987−56.5%Reduced
Pale Fire Capital SE24,004$216.8K0.03%+6,750+39.1%Added
American Century Companies Inc23,980$216.5K0.00%+23,980New
XTX Topco Ltd23,922$216.0K0.01%+23,922New
Renaissance Technologies LLC20,782$187.7K0.00%+20,782New
Raymond James Financial Inc19,960$180.2K0.00%+9,960+99.6%Added
Two Sigma Advisers, LP17,300$156.2K0.00%+17,300New
Schonfeld Strategic Advisors LLC16,645$150.3K0.00%−8,425−33.6%Reduced
Jump Financial, LLC13,400$121.0K0.00%+13,400New
Wells Fargo & Company11,217$101.3K0.00%−6,693−37.4%Reduced
PFS Partners, LLC11,000$99.3K0.05%+2,000+22.2%Added
Royal Bank of Canada7,915$71.0K0.00%00.0%Unchanged
JPMorgan Chase & Co2,614$23.6K0.00%+2,614New
Citigroup Inc1,688$15.2K0.00%+1,687+168,700.0%Added
UBS Group AG1,597$14.4K0.00%+1,597New
MAI Capital Management776$7.01K0.00%00.0%Unchanged
SBI Securities Co., Ltd.28$2530.00%−3−9.7%Reduced
Frazier Life Sciences Management, L.P.0$00.00%−1,157,380−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−1,000,000−100.0%Sold out
Bank of America Corp0$00.00%−647,192−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−504,409−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−11,074−100.0%Sold out
Toronto Dominion Bank0$00.00%−10,000−100.0%Sold out