| Jul 16, 2021 (view filing)4:27 PM ET | Jul 16 | Same day | OrbiMed Advisors LLC and 2 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.67M | $6.00 | +$10.0M | New position1.67M after | |
| Jul 23, 2021 (view filing) | Jul 16 | 7 days | Bonita David PDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.67M | $6.00 | +$10.0M | +65.8%4.20M after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jul 23, 2021 (view filing)5:30 PM ET | Jul 16 | 7 days | OrbiMed Advisors LLC and 1 otherDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.67M | $6.00 | +$10.0M | +65.8%4.20M after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Jul 28, 2021 (view filing) | Jul 16 | 12 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Chin MarkDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.33M | $6.00 | +$8.00M | +131.9%2.34M after | |
| Dec 27, 2021 (view filing)4:34 PM ET | Dec 9-23 | 18 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −291.2K | $2.36 | −$688.5K | −7.3%3.72M after | 11 lotsThis row combines 11 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 29, 2021 (view filing)6:35 PM ET | Dec 27-29 | 2 days | Florence Anthony A. Jr. and 7 othersDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −67.4K | $2.37 | −$159.5K | −1.8%3.66M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 3, 2022 (view filing)8:15 PM ET | Dec 30, 2021-Jan 3, 2022 | 4 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −116.5K | $2.29 | −$266.9K | −3.2%3.54M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 6, 2022 (view filing)5:35 PM ET | Jan 4-6 | 2 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.9K | $2.26 | −$72.2K | −0.9%3.51M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 11, 2022 (view filing)5:54 PM ET | Jan 7-11 | 4 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.8K | $2.07 | −$38.7K | −0.5%3.49M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 14, 2022 (view filing)5:04 PM ET | Jan 12-14 | 2 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.6K | $1.94 | −$41.8K | −0.6%3.47M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 20, 2022 (view filing)5:20 PM ET | Jan 18-20 | 2 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.6K | $1.83 | −$48.7K | −0.8%3.44M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 25, 2022 (view filing)8:41 PM ET | Jan 21-25 | 4 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −134.6K | $1.50 | −$202.2K | −3.9%3.31M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 14, 2022 (view filing) | Feb 10-14 | 4 days | Mott David MDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +31.8K | $1.23 | +$39.2K | New position31.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 17, 2022 (view filing) | Feb 15-17 | 2 days | Mott David MDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +45.9K | $1.19 | +$54.7K | +144.3%77.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 23, 2022 (view filing) | Feb 18-23 | 5 days | Mott David MDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +151.5K | $1.45 | +$219.7K | +194.8%229.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 7, 2022 (view filing)4:54 PM ET | Apr 5-6 | 2 days | Kerins Patrick J and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −694.6K | $1.08 | −$751.3K | −21.0%2.61M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 25, 2022 (view filing) | Apr 21-22 | 4 days | Leonard Braden Michael10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +560.0K | $1.40 | +$783.8K | +24.3%2.86M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| May 18, 2022 (view filing) | May 16-17 | 2 days | Leonard Braden Michael10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +41.1K | $1.23 | +$50.5K | +1.4%2.90M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 7, 2022 (view filing) | Jun 3-6 | 4 days | Leonard Braden Michael10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +33.4K | $1.14 | +$38.2K | +1.2%2.93M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 21, 2022 (view filing) | Jun 16 | 5 days | Leonard Braden Michael10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +83.2K | $1.11 | +$92.4K | +2.8%3.02M after | |
| Oct 19, 2022 (view filing)4:40 PM ET | Oct 17-19 | 2 days | RA Capital Healthcare Fund LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +506.2K | $3.68 | +$1.86M | +19.3%3.13M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 24, 2022 (view filing)4:41 PM ET | Oct 20-24 | 4 days | RA Capital Healthcare Fund LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +85.9K | $3.92 | +$336.8K | +2.7%3.22M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 12, 2022 (view filing)4:30 PM ET | Dec 8-9 | 4 days | RA Capital Healthcare Fund LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +29.9K | $3.87 | +$115.6K | +0.9%3.25M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 27, 2022 (view filing) | Dec 22-23 | 5 days | Leonard Braden Michael10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −50.0K | $4.06 | −$203.0K | −15.6%270.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 29, 2022 (view filing) | Dec 28-29 | 1 day | Leonard Braden Michael10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $4.04 | −$80.8K | −7.4%250.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 30, 2022 (view filing) | Dec 30 | Same day | Leonard Braden Michael10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $4.04 | −$80.8K | −8.0%230.0K after | |
| Jan 5, 2023 (view filing) | Jan 3 | 2 days | Leonard Braden Michael10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.25M | $4.00 | −$5.00M | −41.4%1.77M after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jan 5, 2023 (view filing)4:43 PM ET | Jan 3 | 2 days | RA Capital Healthcare Fund LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +629.3K | $4.00 | +$2.52M | +19.4%3.88M after | |
| Feb 1, 2023 (view filing) | Jan 30 | 2 days | Ballal Rahul D.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.3K | $3.91 | −$44.2K | −8.6%120.7K after | |
| Feb 1, 2023 (view filing) | Jan 30 | 2 days | Gray MichaelCFO & COO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.60K | $3.92 | −$14.1K | −8.8%37.5K after | |
| Feb 22, 2023 (view filing) | Feb 22 | Same day | Ballal Rahul D.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.9K | $4.66 | −$153.1K | −27.2%87.8K after | |
| Feb 22, 2023 (view filing) | Feb 22 | Same day | Gray MichaelCFO & COO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.86K | $4.67 | −$46.0K | −26.3%27.6K after | |
| Feb 23, 2023 (view filing) | Feb 21-22 | 2 days | Commodore Capital LP10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common stock, par value $0.001 per share | +31.8K | $5.15 | +$163.4K | +1.1%2.87M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 27, 2023 (view filing) | Feb 23 | 4 days | Commodore Capital LP10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common stock, par value $0.001 per share | +621.75 | $22.07 | +$13.7K | +0.1%718.7K after | |
| Aug 28, 2023 (view filing)4:20 PM ET | Aug 24 | 4 days | Schwab Andrew J. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −440.0K | $16.00 | −$7.04M | −33.1%887.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 26, 2023 (view filing) | Sep 25 | 1 day | Kintz SamuelPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.0K | $13.81 | −$165.7K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 28, 2023 (view filing)4:27 PM ET | Sep 26 | 2 days | Schwab Andrew J. and 5 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −197.5K | $15.00 | −$2.96M | −18.8%854.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 3, 2023 (view filing) | Sep 29 | 4 days | Lyssikatos Joseph PChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.0K | $13.62 | −$163.4K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 6, 2023 (view filing) | Nov 3 | 3 days | Kintz SamuelPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.03K | $13.08 | −$105.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 6, 2023 (view filing) | Nov 3 | 3 days | Lyssikatos Joseph PChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.55K | $13.08 | −$111.8K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 21, 2023 (view filing) | Dec 19-20 | 2 days | Heyman Richard A.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.37K | $13.02 | −$30.8K | −1.6%147.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 21, 2023 (view filing) | Dec 20 | 1 day | Heyman Richard A.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.92K | $13.02 | −$24.9K | −6.1%29.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 21, 2023 (view filing) | Dec 19-20 | 2 days | Lyssikatos Joseph PChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.89K | $13.01 | −$115.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 21, 2023 (view filing) | Dec 20 | 1 day | Kintz SamuelPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.78K | $13.01 | −$101.2K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 26, 2023 (view filing) | Dec 21-22 | 5 days | Heyman Richard A.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −175 | $13.00 | −$2.27K | −0.1%147.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 26, 2023 (view filing) | Dec 21-22 | 5 days | Heyman Richard A.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −41 | $13.00 | −$533 | −0.1%29.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 26, 2023 (view filing) | Dec 21-22 | 5 days | Kintz SamuelPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.20K | $13.05 | −$106.9K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 26, 2023 (view filing) | Dec 21-22 | 5 days | Lyssikatos Joseph PChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.57K | $13.07 | −$85.8K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 27, 2023 (view filing) | Dec 22-26 | 5 days | Hohl BenjaminChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.13K | $15.06 | −$17.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 27, 2023 (view filing) | Dec 22-26 | 5 days | Patel AnishChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.08K | $15.03 | −$16.3K | −3.0%35.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
