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Precision Biosciences Inc

DTIL
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001357874

In the last 90 days, Precision Biosciences Inc insiders filed 2 open-market purchases and 0 sales; 95 institutions reported holding it in 13F filings for Q2 2026, worth $138.9M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Precision Biosciences Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
+13 vs. Q3 2025
Shares held
15.1M
+10.4M (+224.7%) vs. Q3 2025
Total value
$62.8M
+$37.1M (+144.7%) vs. Q3 2025
New holders
21
21 more added
Sold out
8
7 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DTIL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 69 institutions
Q1 2021: 128 institutionsQ2 2021: 131 institutionsQ3 2021: 132 institutionsQ4 2021: 134 institutionsQ1 2022: 153 institutionsQ2 2022: 121 institutionsQ3 2022: 103 institutionsQ4 2022: 102 institutionsQ1 2023: 86 institutionsQ2 2023: 77 institutionsQ3 2023: 77 institutionsQ4 2023: 66 institutionsQ1 2024: 43 institutionsQ2 2024: 47 institutionsQ3 2024: 51 institutionsQ4 2024: 55 institutionsQ1 2025: 48 institutionsQ2 2025: 52 institutionsQ3 2025: 56 institutionsQ4 2025: 69 institutionsQ1 2026: 78 institutionsQ2 2026: 95 institutions
Value heldQ4 2025: $62.8M
Q1 2021: $313.0MQ2 2021: $357.6MQ3 2021: $336.5MQ4 2021: $233.4MQ1 2022: $96.6MQ2 2022: $93.5MQ3 2022: $67.2MQ4 2022: $60.1MQ1 2023: $36.5MQ2 2023: $23.0MQ3 2023: $11.8MQ4 2023: $12.8MQ1 2024: $42.8MQ2 2024: $30.8MQ3 2024: $29.8MQ4 2024: $14.7MQ1 2025: $18.1MQ2 2025: $18.6MQ3 2025: $25.7MQ4 2025: $62.8MQ1 2026: $88.1MQ2 2026: $138.9M
Institutions holding DTIL and their total value by quarter
QuarterHoldersValue
Q2 202695$138.9M
Q1 202678$88.1M
Q4 202569$62.8M
Q3 202556$25.7M
Q2 202552$18.6M
Q1 202548$18.1M
Q4 202455$14.7M
Q3 202451$29.8M
Q2 202447$30.8M
Q1 202443$42.8M
Q4 202366$12.8M
Q3 202377$11.8M
Q2 202377$23.0M
Q1 202386$36.5M
Q4 2022102$60.1M
Q3 2022103$67.2M
Q2 2022121$93.5M
Q1 2022153$96.6M
Q4 2021134$233.4M
Q3 2021132$336.5M
Q2 2021131$357.6M
Q1 2021128$313.0M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Precision Biosciences Inc; share changes are against Q3 2025.

Institutions holding DTIL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth103$00.00%−100−49.3%Reduced
TSFG, LLC3$00.00%00.0%Unchanged
Harbour Investments, Inc.3$120.00%00.0%Unchanged
MAI Capital Management7$300.00%00.0%Unchanged
JPMorgan Chase & Co8$330.00%00.0%Unchanged
Investors Research Corp8$330.00%00.0%Unchanged
Farther Finance Advisors, LLC10$420.00%+10New
Federation des caisses Desjardins du Quebec12$500.00%00.0%Unchanged
Jones Financial Companies LLLP13$540.00%−127−90.7%Reduced
GWM Advisors LLC22$900.00%00.0%Unchanged
Wells Fargo & Company35$1460.00%00.0%Unchanged
BNP Paribas Arbitrage, SA82$3410.00%00.0%Unchanged
Advisor Group Holdings, Inc.91$3780.00%00.0%Unchanged
South State Corp.95$3950.00%00.0%Unchanged
Beacon Financial Strategies CORP172$7160.00%+172New
Rhumbline Advisers275$1.14K0.00%00.0%Unchanged
SBI Securities Co., Ltd.468$1.95K0.00%−338−41.9%Reduced
Royal Bank of Canada527$2.00K0.00%+526+52,600.0%Added
CWM, LLC1,005$4.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.1,000$4.16K0.00%00.0%Unchanged
CrossGen Wealth, LLC1,000$4.16K0.00%+1,000New
Newbridge Financial Services Group, Inc.1,600$6.66K0.00%00.0%Unchanged
Simplex Trading, LLC3,413$14.2K0.00%+3,413New
Vivo Capital, LLC4,675$19.4K0.00%00.0%Unchanged
Allworth Financial LP4,769$19.8K0.00%00.0%Unchanged
Barclays PLC5,211$21.7K0.00%+4,827+1,257.0%Added
HBK Sorce Advisory LLC10,034$38.1K0.00%+10,034New
CI Private Wealth, LLC10,000$41.6K0.00%00.0%Unchanged
Bank of America Corp10,244$42.6K0.00%+10,038+4,872.8%Added
Engineers Gate Manager LP10,354$43.1K0.00%+10,354New
Occudo Quantitative Strategies LP12,560$52.3K0.00%+12,560New
LPL Financial LLC14,041$58.4K0.00%+2,000+16.6%Added
Miller Financial Services LLC15,000$62.4K0.07%+5,000+50.0%Added
Citadel Advisors LLC15,748$65.5K0.00%−6,394−28.9%Reduced
Velan Capital Investment Management LP20,000$83.2K0.05%00.0%Unchanged
Dimensional Fund Advisors LP23,757$98.8K0.00%−19,884−45.6%Reduced
Point72 Asset Management, L.P.29,607$123.2K0.00%+29,607New
Jump Financial, LLC35,790$148.9K0.00%+35,790New
XTX Topco Ltd35,929$149.5K0.00%+35,929New
Gsa Capital Partners LLP38,767$161.0K0.01%+21,045+118.8%Added
Trexquant Investment LP40,256$167.5K0.00%+40,256New
Acadian Asset Management LLC56,315$233.0K0.00%−63,044−52.8%Reduced
State Street Corp59,042$245.6K0.00%+20,900+54.8%Added
Omers Administration Corp60,700$252.5K0.00%+60,700New
UBS Group AG61,332$255.1K0.00%+36,856+150.6%Added
Bridgeway Capital Management, LLC61,901$257.5K0.01%00.0%Unchanged
Quadrature Capital Ltd62,129$258.5K0.00%+48,158+344.7%Added
Susquehanna International Group, LLP66,581$277.0K0.00%+66,581New
Quarry LP68,311$284.2K0.05%+8,936+15.1%Added
Marshall Wace, LLP70,915$295.0K0.00%+70,915New
Two Sigma Advisers, LP83,443$347.1K0.00%+31,419+60.4%Added
Northern Trust Corp86,464$359.7K0.00%+48,397+127.1%Added
Commonwealth Equity Services, LLC93,306$388.1K0.00%+37,461+67.1%Added
683 Capital Management, LLC97,085$403.9K0.03%+97,085New
Morgan Stanley99,805$415.2K0.00%+89,331+852.9%Added
Two Sigma Investments, LP139,531$580.4K0.00%+56,439+67.9%Added
BlackRock, Inc.168,331$700.3K0.00%+69,632+70.5%Added
Geode Capital Management, LLC225,657$938.8K0.00%+116,136+106.0%Added
Renaissance Technologies LLC326,477$1.36M0.00%+130,300+66.4%Added
Sphera Funds Management Ltd.396,116$1.65M0.34%+396,116New
Driehaus Capital Management LLC787,700$3.28M0.02%+787,700New
Alyeska Investment Group, L.P.798,000$3.32M0.01%+798,000New
Vanguard Group Inc906,782$3.77M0.00%+414,186+84.1%Added
Lynx1 Capital Management LP993,913$4.13M0.84%−48,683−4.7%Reduced
Boothbay Fund Management, LLC1,066,050$4.43M0.12%+887,515+497.1%Added
Bleichroeder LP1,662,500$6.92M1.22%+587,500+54.7%Added
Octagon Capital Advisors LP1,917,995$7.98M1.00%+1,917,995New
Standard Life Aberdeen plc2,138,603$8.90M0.01%+2,138,603New
Empery Asset Management, LP2,194,635$9.13M8.05%+2,194,635New
Tang Capital Management LLC0$00.00%−653,649−100.0%Sold out
Tejara Capital Ltd0$00.00%−58,752−100.0%Sold out
Virtu Financial LLC0$00.00%−15,166−100.0%Sold out
JustInvest LLC0$00.00%−13,127−100.0%Sold out
National Bank of Canada0$00.00%−7,575−100.0%Sold out
Rise Advisors, LLC0$00.00%−206−100.0%Sold out
UMA Financial Services, Inc.0$00.00%−196−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−69−100.0%Sold out