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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Denali Therapeutics Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
4 filings
3 insiders, $435.3K in total
Insiders trading
3
Net value
−$435.3K
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Denali Therapeutics Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Denali Therapeutics Inc.
NameTitleLast reported holdingLast filingFilings, past year
Chin Peter ScottChief Medical Officer204,538Sep 9, 20261
Thornberry NancyDirector19,686Sep 4, 20262
Schuth Alexander O.COFO and Secretary278,995Sep 3, 20264
Watts Ryan J.President and CEO2,120,384IndirectAug 14, 20263
Baker JulianDirector3,422,366IndirectJun 5, 20262
Baker FelixDirector3,422,366IndirectJun 5, 20262
Baker Bros. Advisors LPDirector3,422,366IndirectJun 5, 20262
Baker Brothers Life Sciences LPDirector3,422,366IndirectJun 5, 20262
667, L.P.Director3,422,366IndirectJun 5, 20262
Baker Bros. Advisors (GP) LLCDirector3,422,366IndirectJun 5, 20262
Flatley Jay TDirector22,628Jun 5, 20261
Klein Peter SDirector33,941Jun 5, 20261
Schenkein David PDirector21,665Jun 5, 20261
Krognes Steve E.Director38,202Jun 5, 20261
Cook Jennifer E.Director32,483Jun 5, 20261
Van Hauwermeiren TimothyDirector17,040Jun 5, 20262
Ho CaroleChief Medical Officer216,585Aug 14, 20250
Tessier-Lavigne MarcDirector1,886,576Jun 5, 20250
Sato Vicki LDirector107,976Jan 3, 20250
Harris ErikDirector17,052Jun 4, 20240
Cole Douglas G.Director26,564Jun 5, 20230

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Mar 19, 2024 (view filing)Mar 154 daysSato Vicki LDirectorSSale−1.67K$20.10−$33.5K−1.4%119.7K after10b5-1
Apr 2, 2024 (view filing)Apr 11 dayKrognes Steve E.DirectorSSale−92.5K$20.50−$1.90M−66.1%47.3K after10b5-1
Apr 17, 2024 (view filing)Apr 152 daysSato Vicki LDirectorSSale−1.67K$18.29−$30.5K−1.4%118.0K after10b5-1
May 17, 2024 (view filing)May 152 daysSato Vicki LDirectorSSale−1.67K$20.39−$34.1K−1.4%116.4K after10b5-1
Jun 10, 2024 (view filing)Jun 64 daysCook Jennifer E.DirectorSSale−1.46K$21.73−$31.7K−6.8%20.0K after10b5-1
Jul 3, 2024 (view filing)Jul 12 daysSato Vicki LDirectorSSale−3.08K$22.14−$68.2K−2.5%119.3K after2 lots10b5-1
Jul 3, 2024 (view filing)Jun 13-Jul 120 daysLateKrognes Steve E.DirectorSSale−30.7K$22.11−$678.7K−47.1%34.4K after3 lots10b5-1
Aug 15, 2024 (view filing)Aug 132 daysHo CaroleChief Medical OfficerSSale−2.34K$22.89−$53.5K−1.6%141.3K after
Aug 15, 2024 (view filing)Aug 132 daysSchuth Alexander O.COFO and SecretarySSale−2.27K$22.89−$52.0K−1.2%186.4K after
Aug 22, 2024 (view filing)Aug 20-212 daysHo CaroleChief Medical OfficerSSale−22.5K$24.49−$549.9K−15.9%118.8K after3 lots10b5-1
Aug 22, 2024 (view filing)Aug 20-212 daysSchuth Alexander O.COFO and SecretarySSale−8.35K$23.99−$200.4K−4.5%178.1K after3 lots10b5-1
Aug 22, 2024 (view filing)Aug 202 daysKrognes Steve E.DirectorSSale−1.73K$23.79−$41.1K−5.0%32.7K after
Aug 22, 2024 (view filing)Aug 202 daysWatts Ryan J.President and CEOSSale−2.26K$23.79−$53.8K−0.9%235.8K after
Sep 4, 2024 (view filing)Sep 31 daySato Vicki LDirectorSSale−3.08K$25.00−$77.0K−2.6%116.2K after2 lots10b5-1
Sep 16, 2024 (view filing)Sep 133 daysSato Vicki LDirectorSSale−1.02K$30.00−$30.6K−0.9%115.2K after10b5-1
Oct 2, 2024 (view filing)Sep 302 daysKrognes Steve E.DirectorSSale−30.0K$29.03−$870.9K−50.8%29.1K after10b5-1
Oct 22, 2024 (view filing)Oct 184 daysWatts Ryan J.President and CEOSSale−40.0K$27.69−$1.11M−14.5%235.8K after10b5-1
Nov 5, 2024 (view filing)Nov 14 daysSato Vicki LDirectorSSale−3.08K$27.07−$83.4K−2.7%112.1K after10b5-1
Nov 12, 2024 (view filing)Nov 75 daysSato Vicki LDirectorSSale−1.02K$30.00−$30.6K−0.9%111.1K after10b5-1
Nov 12, 2024 (view filing)Nov 75 daysSchuth Alexander O.COFO and SecretarySSale−15.6K$29.91−$465.3K−8.0%178.1K after3 lots10b5-1
Nov 13, 2024 (view filing)Nov 112 daysSchenkein David PDirectorSSale−59.4K$32.51−$1.93M−86.6%9.22K after2 lots10b5-1
Jan 3, 2025 (view filing)Jan 21 daySato Vicki LDirectorSSale−3.08K$20.91−$64.4K−2.8%108.0K after10b5-1
Jan 3, 2025 (view filing)Dec 31, 20243 daysKrognes Steve E.DirectorSSale−30.0K$20.25−$607.5K−50.8%29.1K after10b5-1
Jan 8, 2025 (view filing)Jan 71 dayKrognes Steve E.DirectorSSale−3.34K$20.81−$69.5K−11.5%25.8K after
Jan 8, 2025 (view filing)Jan 6-72 daysWatts Ryan J.President and CEOSSale−36.9K$20.34−$751.0K−12.7%253.1K after2 lots
Jan 8, 2025 (view filing)Jan 6-72 daysSchuth Alexander O.COFO and SecretarySSale−15.2K$20.33−$308.3K−5.8%244.3K after2 lots
Jan 8, 2025 (view filing)Jan 6-72 daysHo CaroleChief Medical OfficerSSale−15.2K$20.33−$308.3K−7.9%175.7K after2 lots
Jul 11, 2025 (view filing)Jul 92 daysWatts Ryan J.President and CEOSSale−495.3K$15.00−$7.43M−66.2%253.1K after10b5-1
Aug 14, 2025 (view filing)Aug 12-132 daysHo CaroleChief Medical OfficerSSale−3.74K$13.81−$51.7K−1.7%216.6K after2 lots10b5-1
Aug 14, 2025 (view filing)Aug 122 daysSchuth Alexander O.COFO and SecretarySSale−2.94K$13.58−$39.9K−1.2%242.3K after
Dec 15, 2025 (view filing)4:33 PM ETDec 114 daysBaker Julian and 5 othersDirectorPPurchase+2.29M$17.49+$40.0M–26.0M afterDerivative2 lots
Jan 8, 2026 (view filing)Jan 62 daysWatts Ryan J.President and CEOSSale−35.2K$16.50−$580.8K−10.6%296.8K after
Jan 8, 2026 (view filing)Jan 62 daysSchuth Alexander O.COFO and SecretarySSale−17.2K$16.50−$284.1K−5.7%282.8K after
Aug 13, 2026 (view filing)5:01 PM ETAug 112 daysSchuth Alexander O.COFO and SecretarySSale−2.86K$25.07−$71.6K−1.0%281.8K after
Sep 3, 2026 (view filing)4:17 PM ETSep 12 daysSchuth Alexander O.COFO and SecretarySSale−2.77K$23.44−$64.9K−1.0%279.0K after10b5-1
Sep 4, 2026 (view filing)5:02 PM ETSep 22 daysThornberry NancyDirectorSSale−11.4K$22.90−$261.9K−36.8%19.7K after2 lots10b5-1
Sep 9, 2026 (view filing)4:44 PM ETSep 45 daysChin Peter ScottChief Medical OfficerSSale−1.65K$22.29−$36.9K−0.8%204.5K after