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Cytokinetics Inc

CYTK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001061983

In the last 90 days, Cytokinetics Inc insiders filed 0 open-market purchases and 16 sales; 482 institutions reported holding it in 13F filings for Q2 2026, worth $13.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Cytokinetics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
431
+58 vs. Q3 2025
Shares held
139.5M
−1.24M (−0.9%) vs. Q3 2025
Total value
$8.87B
+$1.13B (+14.6%) vs. Q3 2025
New holders
106
143 more added
Sold out
48
134 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CYTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 431 institutions
Q1 2021: 193 institutionsQ2 2021: 191 institutionsQ3 2021: 211 institutionsQ4 2021: 250 institutionsQ1 2022: 240 institutionsQ2 2022: 263 institutionsQ3 2022: 276 institutionsQ4 2022: 278 institutionsQ1 2023: 263 institutionsQ2 2023: 253 institutionsQ3 2023: 251 institutionsQ4 2023: 347 institutionsQ1 2024: 390 institutionsQ2 2024: 344 institutionsQ3 2024: 348 institutionsQ4 2024: 347 institutionsQ1 2025: 356 institutionsQ2 2025: 312 institutionsQ3 2025: 381 institutionsQ4 2025: 431 institutionsQ1 2026: 441 institutionsQ2 2026: 482 institutions
Value heldQ4 2025: $8.87B
Q1 2021: $1.74BQ2 2021: $1.50BQ3 2021: $3.22BQ4 2021: $4.16BQ1 2022: $3.52BQ2 2022: $4.16BQ3 2022: $5.08BQ4 2022: $4.88BQ1 2023: $3.83BQ2 2023: $3.55BQ3 2023: $3.22BQ4 2023: $9.54BQ1 2024: $8.26BQ2 2024: $7.34BQ3 2024: $7.20BQ4 2024: $6.18BQ1 2025: $5.48BQ2 2025: $4.55BQ3 2025: $7.75BQ4 2025: $8.87BQ1 2026: $9.63BQ2 2026: $13.7B
Institutions holding CYTK and their total value by quarter
QuarterHoldersValue
Q2 2026482$13.7B
Q1 2026441$9.63B
Q4 2025431$8.87B
Q3 2025381$7.75B
Q2 2025312$4.55B
Q1 2025356$5.48B
Q4 2024347$6.18B
Q3 2024348$7.20B
Q2 2024344$7.34B
Q1 2024390$8.26B
Q4 2023347$9.54B
Q3 2023251$3.22B
Q2 2023253$3.55B
Q1 2023263$3.83B
Q4 2022278$4.88B
Q3 2022276$5.08B
Q2 2022263$4.16B
Q1 2022240$3.52B
Q4 2021250$4.16B
Q3 2021211$3.22B
Q2 2021191$1.50B
Q1 2021193$1.74B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Cytokinetics Inc; share changes are against Q3 2025.

Institutions holding CYTK in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Affinity Asset Advisors, LLC800,000$50.8M3.65%+450,000+128.6%Added
Norges Bank807,070$51.3M0.01%+807,070New
Fisher Asset Management, LLC822,885$52.3M0.02%+61,298+8.0%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.827,863$52.6M0.06%+42,863+5.5%Added
Bank of New York Mellon Corp854,309$54.3M0.01%−14,922−1.7%Reduced
Frazier Life Sciences Management, L.P.934,642$59.4M1.60%+44,197+5.0%Added
Principal Financial Group Inc976,892$62.1M0.03%−197,556−16.8%Reduced
Royalty Pharma Sub-Manager, LLC980,392$62.3M36.36%+980,392New
Armistice Capital, LLC992,766$63.1M1.54%−204,102−17.1%Reduced
UBS Group AG1,131,456$71.9M0.01%−671,795−37.3%Reduced
Citadel Advisors LLC1,162,937$73.9M0.05%−223,128−16.1%Reduced
Capital International Investors1,178,780$74.9M0.01%00.0%Unchanged
Morgan Stanley1,265,301$80.4M0.00%−255,885−16.8%Reduced
Northern Trust Corp1,380,787$87.7M0.01%−26,045−1.9%Reduced
Charles Schwab Investment Management Inc1,383,437$87.9M0.01%+9,554+0.7%Added
Integral Health Asset Management, LLC1,400,000$89.0M4.51%00.0%Unchanged
JPMorgan Chase & Co1,412,797$89.8M0.01%−130,060−8.4%Reduced
Woodline Partners LP1,648,428$104.7M0.41%+7030.0%Added
Price T Rowe Associates Inc1,930,119$122.6M0.01%−436,729−18.5%Reduced
Goldman Sachs Group Inc2,371,679$150.7M0.02%+736,956+45.1%Added
Polar Capital Holdings Plc2,422,612$153.9M0.70%−360,318−12.9%Reduced
RTW Investments, LP2,721,158$172.9M1.73%00.0%Unchanged
Bank of America Corp2,941,152$186.9M0.01%−120,644−3.9%Reduced
Geode Capital Management, LLC3,056,017$194.2M0.01%+15,815+0.5%Added
Deep Track Capital, LP3,336,998$212.0M4.84%−963,002−22.4%Reduced
State Street Corp5,825,295$370.1M0.01%+207,961+3.7%Added
Wellington Management Group LLP7,937,063$504.3M0.09%+528,502+7.1%Added
Vanguard Group Inc12,048,131$765.5M0.01%+191,336+1.6%Added
FMR LLC12,807,752$813.8M0.04%−283,895−2.2%Reduced
BlackRock, Inc.16,395,123$1.04B0.02%+869,376+5.6%Added
T. Rowe Price Investment Management, Inc.17,716,372$1.13B0.71%−1,364,124−7.1%Reduced
Vestal Point Capital, LP0$00.00%−725,000−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−471,482−100.0%Sold out
Pentwater Capital Management LP0$00.00%−300,000−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−211,000−100.0%Sold out
Schroder Investment Management Group0$00.00%−186,883−100.0%Sold out
Great Point Partners LLC0$00.00%−150,000−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−150,000−100.0%Sold out
Monaco Asset Management SAM0$00.00%−120,000−100.0%Sold out
Macquarie Group Ltd0$00.00%−110,260−100.0%Sold out
Squarepoint Ops LLC0$00.00%−105,180−100.0%Sold out
Tang Capital Management LLC0$00.00%−100,000−100.0%Sold out
Weiss Asset Management LP0$00.00%−64,163−100.0%Sold out
Alps Advisors Inc0$00.00%−56,619−100.0%Sold out
Zimmer Partners, LP0$00.00%−50,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−41,004−100.0%Sold out
Philadelphia Financial Management of San Francisco, LLC0$00.00%−39,523−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−38,000−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−30,504−100.0%Sold out
Bamco Inc0$00.00%−24,500−100.0%Sold out
Jain Global LLC0$00.00%−24,418−100.0%Sold out
Sanders Morris Harris LLC0$00.00%−21,505−100.0%Sold out
NJ State Employees Deferred Compensation Plan0$00.00%−15,500−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−12,094−100.0%Sold out
Bayforest Capital Ltd0$00.00%−11,747−100.0%Sold out
DLD Asset Management, LP0$00.00%−11,000−100.0%Sold out
Concentric Capital Strategies, LP0$00.00%−8,788−100.0%Sold out
Groupama Asset Managment0$00.00%–Sold out
Fifth Lane Capital, LP0$00.00%−8,000−100.0%Sold out
Clearline Capital LP0$00.00%−6,817−100.0%Sold out
ISAM Funds (UK) Ltd0$00.00%−5,227−100.0%Sold out
PharVision Advisers, LLC0$00.00%−3,765−100.0%Sold out
Massar Capital Management, LP0$00.00%−3,740−100.0%Sold out
Inceptionr LLC0$00.00%−3,719−100.0%Sold out
Wexford Capital LP0$00.00%−1,449−100.0%Sold out
BIT Capital GmbH0$00.00%−1,254−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−811−100.0%Sold out
Manchester Capital Management LLC0$00.00%−720−100.0%Sold out
Advisory Services Network, LLC0$00.00%−574−100.0%Sold out
Rise Advisors, LLC0$00.00%−476−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−375−100.0%Sold out
Ci Investments Inc.0$00.00%−194−100.0%Sold out
Goodman Advisory Group, LLC0$00.00%−52−100.0%Sold out
Washington Trust Advisors, Inc.0$00.00%−49−100.0%Sold out
Principal Securities, Inc.0$00.00%−13−100.0%Sold out
Vermillion Wealth Management, Inc.0$00.00%−10−100.0%Sold out
Montag A & Associates Inc0$00.00%−6−100.0%Sold out
Ronald Blue Trust, Inc.0$00.00%−5−100.0%Sold out
Strategic Advocates LLC0$00.00%−2−100.0%Sold out
EFG Asset Management (North America) Corp.––––Not filed
HAP Trading, LLC––––Not filed
Wolverine Trading, LLC––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Glenmede Investment Management, LP––––Not filed
Point72 (DIFC) Ltd––––Not filed
Hemington Wealth Management––––Not filed