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Cytokinetics Inc

CYTK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001061983

In the last 90 days, Cytokinetics Inc insiders filed 0 open-market purchases and 16 sales; 482 institutions reported holding it in 13F filings for Q2 2026, worth $13.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Cytokinetics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
431
+58 vs. Q3 2025
Shares held
139.5M
−1.24M (−0.9%) vs. Q3 2025
Total value
$8.87B
+$1.13B (+14.6%) vs. Q3 2025
New holders
106
143 more added
Sold out
48
134 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CYTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 431 institutions
Q1 2021: 193 institutionsQ2 2021: 191 institutionsQ3 2021: 211 institutionsQ4 2021: 250 institutionsQ1 2022: 240 institutionsQ2 2022: 263 institutionsQ3 2022: 276 institutionsQ4 2022: 278 institutionsQ1 2023: 263 institutionsQ2 2023: 253 institutionsQ3 2023: 251 institutionsQ4 2023: 347 institutionsQ1 2024: 390 institutionsQ2 2024: 344 institutionsQ3 2024: 348 institutionsQ4 2024: 347 institutionsQ1 2025: 356 institutionsQ2 2025: 312 institutionsQ3 2025: 381 institutionsQ4 2025: 431 institutionsQ1 2026: 441 institutionsQ2 2026: 482 institutions
Value heldQ4 2025: $8.87B
Q1 2021: $1.74BQ2 2021: $1.50BQ3 2021: $3.22BQ4 2021: $4.16BQ1 2022: $3.52BQ2 2022: $4.16BQ3 2022: $5.08BQ4 2022: $4.88BQ1 2023: $3.83BQ2 2023: $3.55BQ3 2023: $3.22BQ4 2023: $9.54BQ1 2024: $8.26BQ2 2024: $7.34BQ3 2024: $7.20BQ4 2024: $6.18BQ1 2025: $5.48BQ2 2025: $4.55BQ3 2025: $7.75BQ4 2025: $8.87BQ1 2026: $9.63BQ2 2026: $13.7B
Institutions holding CYTK and their total value by quarter
QuarterHoldersValue
Q2 2026482$13.7B
Q1 2026441$9.63B
Q4 2025431$8.87B
Q3 2025381$7.75B
Q2 2025312$4.55B
Q1 2025356$5.48B
Q4 2024347$6.18B
Q3 2024348$7.20B
Q2 2024344$7.34B
Q1 2024390$8.26B
Q4 2023347$9.54B
Q3 2023251$3.22B
Q2 2023253$3.55B
Q1 2023263$3.83B
Q4 2022278$4.88B
Q3 2022276$5.08B
Q2 2022263$4.16B
Q1 2022240$3.52B
Q4 2021250$4.16B
Q3 2021211$3.22B
Q2 2021191$1.50B
Q1 2021193$1.74B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Cytokinetics Inc; share changes are against Q3 2025.

Institutions holding CYTK in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GAMMA Investing LLC2,056$130.6K0.01%+584+39.7%Added
Canada Pension Plan Investment Board2,100$133.4K0.00%+2,100New
Jones Financial Companies LLLP2,230$141.7K0.00%+372+20.0%Added
NBC Securities, Inc.2,284$145.1K0.01%+1,903+499.5%Added
GF Fund Management Co. Ltd.2,402$152.6K0.00%−172−6.7%Reduced
Acadian Asset Management LLC2,541$160.0K0.00%+2,541New
Bessemer Group Inc3,007$191.0K0.00%+427+16.6%Added
Assetmark, Inc3,025$192.2K0.00%−338−10.1%Reduced
Parallax Volatility Advisers, L.P.3,039$193.1K0.01%+130+4.5%Added
Ascent Group, LLC3,149$200.1K0.01%+3,149New
Journey Strategic Wealth LLC3,183$202.2K0.01%+3,183New
CIBC Asset Management Inc3,187$202.5K0.00%+3,187New
Fifth Third Wealth Advisors LLC3,209$203.9K0.01%+3,209New
Persistent Asset Partners Ltd3,214$204.2K0.10%+3,214New
Fiduciary Trust Co3,249$206.4K0.00%+3,249New
Pennington Partners & Co., LLC3,278$208.3K0.08%+3,278New
Ellevest, Inc.3,324$211.2K0.03%+3,324New
AE Wealth Management LLC3,396$215.8K0.00%+3,396New
Evergreen Capital Management LLC3,401$216.1K0.00%+3,401New
Bailard, Inc.3,425$217.6K0.00%+3,425New
KBC Group NV3,470$220.0K0.00%00.0%Unchanged
Meridian Financial, LLC3,583$227.7K0.12%−535−13.0%Reduced
Shay Capital LLC3,586$227.9K0.04%−2,429−40.4%Reduced
Wiley Bros.-Aintree Capital, LLC3,636$231.0K0.00%+3,636New
Abel Hall, LLC3,666$232.9K0.05%+3,666New
Blueshift Asset Management, LLC3,679$233.8K0.07%+3,679New
HSBC Holdings PLC3,696$234.8K0.00%−310−7.7%Reduced
CIBC Private Wealth Group, LLC3,723$236.6K0.00%+239+6.9%Added
Sanctuary Advisors, LLC3,741$237.7K0.00%+3,741New
OP Asset Management Ltd3,767$239.4K0.00%+281+8.1%Added
Meeder Advisory Services, Inc.3,809$242.0K0.01%+3,809New
Oppenheimer & Co Inc3,922$249.2K0.00%−450−10.3%Reduced
Breakwater Capital Group3,941$250.4K0.03%+2+0.1%Added
Commerce Bank3,967$252.1K0.00%+3,967New
LVW Advisors, LLC3,982$253.0K0.03%00.0%Unchanged
Shelton Capital Management4,049$257.3K0.01%+4,049New
Everence Capital Management Inc4,080$259.0K0.02%00.0%Unchanged
Savant Capital, LLC4,104$260.8K0.00%−104−2.5%Reduced
Headlands Technologies LLC4,199$266.8K0.02%+4,199New
Empowered Funds, LLC4,237$269.2K0.00%−106−2.4%Reduced
Virtus Investment Advisers, Inc.4,247$269.9K0.07%+819+23.9%Added
Arrowpoint Investment Partners (Singapore) Pte. Ltd.4,480$284.7K0.04%+4,480New
Captrust Financial Advisors4,649$295.4K0.00%+4,649New
MML Investors Services, LLC4,842$307.7K0.00%+4,842New
Commonwealth Equity Services, LLC4,845$307.9K0.00%−287−5.6%Reduced
US Bancorp4,920$312.6K0.00%+612+14.2%Added
Virginia Retirement Systems Et Al4,950$314.5K0.00%+4,950New
Tower Research Capital LLC (TRC)4,978$316.3K0.01%−1,365−21.5%Reduced
High Net Worth Advisory Group LLC5,000$317.7K0.07%00.0%Unchanged
O'Shaughnessy Asset Management, LLC5,007$318.1K0.00%+677+15.6%Added
Swiss Life Asset Management Ltd5,142$326.7K0.00%00.0%Unchanged
Intrust Bank NA5,169$328.4K0.03%+616+13.5%Added
FNY Investment Advisers, LLC5,260$334.0K0.10%−3,354−38.9%Reduced
AlphaCentric Advisors LLC5,311$337.5K0.34%+5,311New
Coldstream Capital Management Inc5,320$338.0K0.00%+568+12.0%Added
Summit Trail Advisors, LLC5,388$342.4K0.01%−376−6.5%Reduced
Wolverine Asset Management LLC5,500$349.5K0.00%+5,500New
Jasper Ridge Partners, L.P.5,500$349.5K0.01%+5,500New
Aigen Investment Management, LP5,568$353.8K0.08%+5,568New
Carlson Capital L P5,600$355.8K0.17%+900+19.1%Added
Y-Intercept (Hong Kong) Ltd5,790$367.9K0.01%−18,942−76.6%Reduced
Camden Capital, LLC5,889$374.2K0.02%−700−10.6%Reduced
Sectoral Asset Management Inc5,893$374.4K0.30%−4,330−42.4%Reduced
Mirae Asset Global Investments Co., Ltd.5,941$377.5K0.00%+1,315+28.4%Added
Alpine Global Management, LLC6,000$381.2K0.08%+6,000New
VARCOV Co.6,013$382.1K0.15%+6,013New
Los Angeles Capital Management LLC6,171$384.1K0.00%+6,171New
Sterling Capital Management LLC6,142$390.3K0.01%−1,091−15.1%Reduced
Allspring Global Investments Holdings, LLC6,343$391.6K0.00%+679+12.0%Added
Banque Pictet & Cie SA6,184$392.9K0.00%−1,455−19.0%Reduced
J.Safra Asset Management Corp6,291$399.7K0.02%+952+17.8%Added
First Bank & Trust6,407$407.1K0.07%+103+1.6%Added
Cinctive Capital Management LP6,562$416.9K0.02%−99,079−93.8%Reduced
Amundi6,773$430.4K0.00%+6,773New
Hantz Financial Services, Inc.6,844$435.0K0.01%+2,231+48.4%Added
Cerity Partners LLC6,874$436.8K0.00%+6,874New
CI Private Wealth, LLC7,044$447.1K0.00%+2,231+46.4%Added
Quest Partners LLC7,224$459.0K0.03%+2,365+48.7%Added
Allianz Asset Management GmbH7,241$460.1K0.00%+2,700+59.5%Added
Ensign Peak Advisors, Inc7,296$463.6K0.00%−13,200−64.4%Reduced
CWM Advisors, LLC7,330$465.7K0.04%−862−10.5%Reduced
Cynosure Management, LLC7,354$467.3K0.05%−3,018−29.1%Reduced
Veracity Capital LLC7,414$471.1K0.14%00.0%Unchanged
CIBC World Markets Corp7,729$491.1K0.00%+7,729New
Havemeyer Place LP7,923$503.4K0.10%+7,923New
Marex Group plc8,002$508.4K0.01%+8,002New
Polymer Capital Management (US) LLC8,014$509.2K0.07%+8,014New
Crossmark Global Holdings, Inc.8,162$518.6K0.01%+347+4.4%Added
PSP Research LLC8,313$528.2K0.46%+8,313New
The PNC Financial Services Group, Inc.8,524$541.6K0.00%+2,475+40.9%Added
Qsemble Capital Management, LP8,560$543.9K0.04%+2,495+41.1%Added
Securian Asset Management, Inc8,910$566.1K0.02%−51−0.6%Reduced
Bellevue Group AG9,225$586.2K0.01%+7,125+339.3%Added
Bridgefront Capital, LLC9,484$602.6K0.15%−925−8.9%Reduced
Polen Capital Management LLC9,584$609.0K0.00%+9,584New
Lighthouse Investment Partners, LLC10,000$635.4K0.02%−37,000−78.7%Reduced
Creek Drive Management Group LLC10,000$635.4K0.47%+10,000New
Wealth Enhancement Advisory Services, LLC9,982$644.8K0.00%+126+1.3%Added
Skopos Labs, Inc.10,566$652.4K0.03%+10,566New
Seven Fleet Capital Management LP10,335$656.7K0.44%+10,335New