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Clene Inc.

CLNN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001822791

No open-market purchases or sales by Clene Inc. insiders were filed in the last 90 days; 33 institutions reported holding it in 13F filings for Q2 2026, worth $19.6M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Clene Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
28
−1 vs. Q3 2025
Shares held
1.94M
+1.15M (+147.2%) vs. Q3 2025
Total value
$11.4M
+$6.65M (+140.9%) vs. Q3 2025
New holders
3
12 more added
Sold out
4
4 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CLNN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 28 institutions
Q1 2021: 24 institutionsQ2 2021: 35 institutionsQ3 2021: 39 institutionsQ4 2021: 48 institutionsQ1 2022: 53 institutionsQ2 2022: 42 institutionsQ3 2022: 38 institutionsQ4 2022: 35 institutionsQ1 2023: 31 institutionsQ2 2023: 50 institutionsQ3 2023: 47 institutionsQ4 2023: 46 institutionsQ1 2024: 44 institutionsQ2 2024: 37 institutionsQ3 2024: 20 institutionsQ4 2024: 27 institutionsQ1 2025: 24 institutionsQ2 2025: 24 institutionsQ3 2025: 29 institutionsQ4 2025: 28 institutionsQ1 2026: 29 institutionsQ2 2026: 33 institutions
Value heldQ4 2025: $11.4M
Q1 2021: $31.2MQ2 2021: $51.6MQ3 2021: $37.8MQ4 2021: $26.0MQ1 2022: $24.7MQ2 2022: $8.93MQ3 2022: $12.1MQ4 2022: $3.09MQ1 2023: $3.42MQ2 2023: $28.1MQ3 2023: $12.3MQ4 2023: $3.50MQ1 2024: $3.10MQ2 2024: $2.40MQ3 2024: $4.66MQ4 2024: $2.60MQ1 2025: $1.40MQ2 2025: $2.28MQ3 2025: $4.72MQ4 2025: $11.4MQ1 2026: $10.8MQ2 2026: $19.6M
Institutions holding CLNN and their total value by quarter
QuarterHoldersValue
Q2 202633$19.6M
Q1 202629$10.8M
Q4 202528$11.4M
Q3 202529$4.72M
Q2 202524$2.28M
Q1 202524$1.40M
Q4 202427$2.60M
Q3 202420$4.66M
Q2 202437$2.40M
Q1 202444$3.10M
Q4 202346$3.50M
Q3 202347$12.3M
Q2 202350$28.1M
Q1 202331$3.42M
Q4 202235$3.09M
Q3 202238$12.1M
Q2 202242$8.93M
Q1 202253$24.7M
Q4 202148$26.0M
Q3 202139$37.8M
Q2 202135$51.6M
Q1 202124$31.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Clene Inc.; share changes are against Q3 2025.

Institutions holding CLNN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
SymBiosis Capital Partners, LLC770,495$4.52M4.13%+770,495New
Scoggin Management LP275,000$1.61M0.60%+25,000+10.0%Added
Vanguard Group Inc222,909$1.31M0.00%+21,930+10.9%Added
Boxer Capital Management, LLC199,737$1.17M0.26%+199,737New
Ensign Peak Advisors, Inc114,361$671.3K0.00%+99,481+668.6%Added
Geode Capital Management, LLC82,079$481.9K0.00%+6,090+8.0%Added
Lunt Capital Management, Inc.52,260$306.8K0.11%00.0%Unchanged
PEAK6 LLC50,012$293.6K0.01%+50,012New
Parsons Capital Management Inc37,243$218.6K0.01%00.0%Unchanged
BlackRock, Inc.33,852$198.7K0.00%+29,681+711.6%Added
State Street Corp29,801$174.9K0.00%+17,300+138.4%Added
Morgan Stanley20,429$119.9K0.00%+515+2.6%Added
Northern Trust Corp16,143$94.8K0.00%−659−3.9%Reduced
Penn Davis McFarland Inc11,000$64.6K0.01%00.0%Unchanged
Wells Fargo & Company5,927$34.8K0.00%+1,680+39.6%Added
Jones Financial Companies LLLP5,000$29.4K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.2,735$16.1K0.00%00.0%Unchanged
UBS Group AG2,638$15.5K0.00%+2,623+17,486.7%Added
Atlantic Private Wealth, LLC2,205$12.9K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.1,926$11.3K0.00%+440+29.6%Added
Group One Trading, L.P.686$4.03K0.00%−33−4.6%Reduced
SRS Capital Advisors, Inc.570$3.35K0.00%−2,640−82.2%Reduced
Bank of America Corp122$7160.00%+55+82.1%Added
MAI Capital Management100$5870.00%00.0%Unchanged
FMR LLC48$2820.00%+47+4,700.0%Added
SBI Securities Co., Ltd.25$1470.00%−15,000−99.8%Reduced
BNP Paribas Arbitrage, SA23$1350.00%00.0%Unchanged
US Bancorp20$1170.00%00.0%Unchanged
Renaissance Technologies LLC0$00.00%−30,440−100.0%Sold out
Marshall Wace, LLP0$00.00%−22,709−100.0%Sold out
Principal Securities, Inc.0$00.00%−15−100.0%Sold out
Citigroup Inc0$00.00%−1−100.0%Sold out