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Blueprint Medicines Corp

BPMCDelisted Jul 18, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001597264

Blueprint Medicines Corp was delisted on Jul 18, 2025; its insiders filed their last Form 4 on Jul 21, 2025; 356 institutions reported holding it in 13F filings for Q2 2025, worth $8.65B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Blueprint Medicines Corp as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
353
+10 vs. Q4 2024
Shares held
69.1M
+2.38M (+3.6%) vs. Q4 2024
Total value
$6.12B
+$298.8M (+5.1%) vs. Q4 2024
New holders
62
132 more added
Sold out
52
115 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BPMC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 353 institutions
Q1 2021: 264 institutionsQ2 2021: 281 institutionsQ3 2021: 289 institutionsQ4 2021: 280 institutionsQ1 2022: 248 institutionsQ2 2022: 237 institutionsQ3 2022: 240 institutionsQ4 2022: 223 institutionsQ1 2023: 215 institutionsQ2 2023: 222 institutionsQ3 2023: 220 institutionsQ4 2023: 260 institutionsQ1 2024: 282 institutionsQ2 2024: 305 institutionsQ3 2024: 319 institutionsQ4 2024: 346 institutionsQ1 2025: 353 institutionsQ2 2025: 356 institutionsQ3 2025: 12 institutionsQ4 2025: 8 institutionsQ1 2026: 6 institutionsQ2 2026: 4 institutions
Value heldQ1 2025: $6.12B
Q1 2021: $5.69BQ2 2021: $5.14BQ3 2021: $6.13BQ4 2021: $6.32BQ1 2022: $3.82BQ2 2022: $3.19BQ3 2022: $4.15BQ4 2022: $2.74BQ1 2023: $2.84BQ2 2023: $4.03BQ3 2023: $3.25BQ4 2023: $5.91BQ1 2024: $6.25BQ2 2024: $7.15BQ3 2024: $6.04BQ4 2024: $5.86BQ1 2025: $6.12BQ2 2025: $8.65BQ3 2025: $2.58MQ4 2025: $2.57MQ1 2026: $38.6KQ2 2026: $129
Institutions holding BPMC and their total value by quarter
QuarterHoldersValue
Q2 20264$129
Q1 20266$38.6K
Q4 20258$2.57M
Q3 202512$2.58M
Q2 2025356$8.65B
Q1 2025353$6.12B
Q4 2024346$5.86B
Q3 2024319$6.04B
Q2 2024305$7.15B
Q1 2024282$6.25B
Q4 2023260$5.91B
Q3 2023220$3.25B
Q2 2023222$4.03B
Q1 2023215$2.84B
Q4 2022223$2.74B
Q3 2022240$4.15B
Q2 2022237$3.19B
Q1 2022248$3.82B
Q4 2021280$6.32B
Q3 2021289$6.13B
Q2 2021281$5.14B
Q1 2021264$5.69B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Blueprint Medicines Corp; share changes are against Q4 2024.

Institutions holding BPMC in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.6,710,708$594.0M0.01%−158,619−2.3%Reduced
Vanguard Group Inc6,640,523$587.8M0.01%−134,361−2.0%Reduced
Price T Rowe Associates Inc5,415,837$479.4M0.06%−263,252−4.6%Reduced
Avoro Capital Advisors LLC3,850,000$340.8M5.32%+2,665,000+224.9%Added
Wellington Management Group LLP3,073,306$272.0M0.05%−1,208,058−28.2%Reduced
State Street Corp2,684,117$237.6M0.01%+183,910+7.4%Added
JPMorgan Chase & Co2,506,514$221.9M0.02%+1,350,880+116.9%Added
Geode Capital Management, LLC1,522,647$134.8M0.01%+32,546+2.2%Added
FMR LLC1,433,169$126.8M0.01%−814,510−36.2%Reduced
William Blair Investment Management, LLC1,429,668$126.5M0.36%−515,027−26.5%Reduced
T. Rowe Price Investment Management, Inc.1,302,810$115.3M0.08%+605,783+86.9%Added
Macquarie Group Ltd1,286,897$113.9M0.14%+27,921+2.2%Added
Alliancebernstein L.P.1,196,240$105.9M0.04%+58,218+5.1%Added
Rock Springs Capital Management LP1,007,569$89.2M5.10%−89,330−8.1%Reduced
Invesco Ltd.984,674$87.2M0.02%+24,237+2.5%Added
Pictet Asset Management Holding SA954,596$84.5M0.09%−229,086−19.4%Reduced
Goldman Sachs Group Inc926,668$82.0M0.02%−119,867−11.5%Reduced
Alkeon Capital Management LLC900,628$79.7M0.47%+100,000+12.5%Added
Hood River Capital Management LLC900,205$79.7M1.36%+20,273+2.3%Added
American Century Companies Inc866,763$76.7M0.05%+27,560+3.3%Added
Eventide Asset Management, LLC862,549$76.3M1.52%+2640.0%Added
Siren, L.L.C.726,167$64.3M3.63%+726,167New
Bank of America Corp716,906$63.5M0.01%+321,875+81.5%Added
Millennium Management LLC691,395$61.2M0.06%−45,969−6.2%Reduced
Clearbridge Investments, LLC671,617$59.4M0.05%+180,838+36.8%Added
Norges Bank602,927$53.4M0.01%−108,237−15.2%Reduced
Charles Schwab Investment Management Inc599,721$53.1M0.01%−4,676−0.8%Reduced
Northern Trust Corp589,559$52.2M0.01%−18,833−3.1%Reduced
Brown Advisory Inc581,864$51.5M0.07%+3,084+0.5%Added
Jacobs Levy Equity Management, Inc570,402$50.5M0.20%−78,258−12.1%Reduced
Morgan Stanley568,699$50.3M0.00%+64,356+12.8%Added
Polar Capital Holdings Plc541,379$47.9M0.30%−85,000−13.6%Reduced
Woodline Partners LP540,738$47.9M0.31%+546+0.1%Added
Man Group plc519,737$46.0M0.14%+415,818+400.1%Added
Braidwell LP439,968$38.9M1.37%+439,968New
Susquehanna International Group, LLP412,540$36.5M0.06%+276,329+202.9%Added
Emerald Advisers, LLC401,644$35.5M1.60%−15,222−3.7%Reduced
D. E. Shaw & Co., Inc.388,986$34.4M0.04%+27,185+7.5%Added
Jane Street Group, LLC375,818$33.3M0.06%−32,404−7.9%Reduced
Ameriprise Financial Inc361,508$32.0M0.01%+23,393+6.9%Added
Jennison Associates LLC348,817$30.9M0.02%−11,391−3.2%Reduced
Qube Research & Technologies Ltd337,151$29.8M0.05%−12,939−3.7%Reduced
Casdin Capital, LLC326,378$28.9M2.36%00.0%Unchanged
Capital Research Global Investors311,137$27.5M0.01%+311,137New
Fisher Asset Management, LLC310,734$27.5M0.01%−12,306−3.8%Reduced
Bank of New York Mellon Corp307,018$27.2M0.01%+3,586+1.2%Added
Citigroup Inc304,838$27.0M0.02%+209,656+220.3%Added
Ensign Peak Advisors, Inc303,732$26.9M0.05%+28,308+10.3%Added
Lord, Abbett & Co. LLC288,472$25.5M0.09%−46,571−13.9%Reduced
TD Asset Management Inc284,372$25.2M0.02%−19,128−6.3%Reduced
Massachusetts Financial Services Co270,996$24.0M0.01%+1,006+0.4%Added
Nuveen, LLC267,660$23.4M0.01%+267,660New
Sofinnova Investments, Inc.261,039$23.1M1.74%+261,039New
Emerald Mutual Fund Advisers Trust250,158$22.1M1.57%−18,820−7.0%Reduced
UBS Asset Management Americas Inc244,411$21.6M0.01%+4,465+1.9%Added
Driehaus Capital Management LLC242,938$21.5M0.21%+242,938New
Voya Investment Management LLC241,672$21.4M0.02%+36,281+17.7%Added
Novo Holdings A/S228,804$20.3M1.54%+53,804+30.7%Added
UBS Group AG213,805$18.9M0.00%+16,345+8.3%Added
Panagora Asset Management Inc205,582$18.2M0.09%+134,166+187.9%Added
Deutsche Bank AG199,937$17.7M0.01%−61,426−23.5%Reduced
Raymond James Financial Inc193,812$17.2M0.01%−48,154−19.9%Reduced
Connor, Clark & Lunn Investment Management Ltd.183,947$16.3M0.07%+41,230+28.9%Added
Russell Investments Group, Ltd.169,115$15.0M0.02%+43,213+34.3%Added
Manufacturers Life Insurance Company, The164,055$14.5M0.01%−12,429−7.0%Reduced
DAFNA Capital Management LLC152,263$13.5M3.82%+2,500+1.7%Added
AQR Capital Management LLC148,271$13.1M0.01%+3,578+2.5%Added
Integral Health Asset Management, LLC145,000$12.8M1.42%−130,000−47.3%Reduced
Granahan Investment Management Inc144,756$12.8M0.64%+2,866+2.0%Added
Franklin Resources Inc136,111$12.0M0.00%+99,525+272.0%Added
Segall Bryant & Hamill, LLC135,909$12.0M0.18%−3,834−2.7%Reduced
Barclays PLC129,595$11.5M0.01%−59,532−31.5%Reduced
Swiss National Bank123,100$10.9M0.01%−1,500−1.2%Reduced
Ikarian Capital, LLC113,904$10.1M3.28%−55,470−32.8%Reduced
Orion Investment Co109,033$9.65M3.97%+363+0.3%Added
Rafferty Asset Management, LLC99,320$8.79M0.04%+10,429+11.7%Added
Peregrine Capital Management LLC96,149$8.51M0.28%−2,663−2.7%Reduced
Legal & General Group Plc95,666$8.47M0.00%+1,150+1.2%Added
Prudential Financial Inc93,468$8.27M0.01%−7,070−7.0%Reduced
First Turn Management, LLC92,033$8.15M1.64%+24,890+37.1%Added
Rhumbline Advisers91,933$8.14M0.01%+5,402+6.2%Added
Capital Fund Management S.A.91,492$8.10M0.10%+1,587+1.8%Added
Universal- Beteiligungs- und Servicegesellschaft mbH84,780$7.50M0.02%+84,780New
Aquilo Capital Management, LLC83,926$7.43M20.03%−45,674−35.2%Reduced
BIT Capital GmbH77,802$6.89M0.83%−1,119−1.4%Reduced
California Public Employees Retirement System77,556$6.86M0.00%−894−1.1%Reduced
Assenagon Asset Management S.A.76,270$6.75M0.01%−21,083−21.7%Reduced
Oberweis Asset Management Inc75,000$6.64M0.33%00.0%Unchanged
Aquatic Capital Management LLC74,574$6.60M0.17%+26,972+56.7%Added
Ally Bridge Group (NY) LLC74,192$6.57M5.92%+18,300+32.7%Added
EFG Asset Management (North America) Corp.73,388$6.50M1.08%−912−1.2%Reduced
SEI Investments Co70,463$6.24M0.01%+79+0.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.69,887$6.18M0.02%00.0%Unchanged
Avidity Partners Management LP68,500$6.06M1.25%−108,100−61.2%Reduced
Algert Global LLC68,420$6.06M0.15%−43,752−39.0%Reduced
Neuberger Berman Group LLC67,794$6.00M0.01%+1,399+2.1%Added
State of Wisconsin Investment Board64,066$5.67M0.01%+22,009+52.3%Added
StemPoint Capital LP61,927$5.48M1.75%+61,927New
Balyasny Asset Management LLC60,282$5.34M0.01%−42,204−41.2%Reduced
California State Teachers Retirement System58,588$5.19M0.01%−671−1.1%Reduced