| Jul 2, 2021 (view filing) | Jun 30 | 2 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $76.69 | −$1.53M | −87.9%2.75K after | |
| Jul 30, 2021 (view filing) | Jul 28 | 2 days | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.2K | $100.00 | −$1.72M | −9.8%158.2K after | |
| Aug 4, 2021 (view filing) | Aug 2 | 2 days | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −45.9K | $97.83 | −$4.49M | −5.3%827.6K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 13, 2021 (view filing) | Aug 11-13 | 2 days | Margus Bradley AlbertDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.8K | $90.03 | −$974.8K | −25.3%31.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 16, 2021 (view filing) | Aug 12 | 4 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.36K | $90.54 | −$123.4K | −20.1%5.40K after | |
| Aug 18, 2021 (view filing) | Aug 16 | 2 days | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $87.30 | −$1.75M | −20.3%78.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 27, 2021 (view filing) | Aug 25-26 | 2 days | Margus Bradley AlbertDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.9K | $85.01 | −$2.55M | −93.7%2.00K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Aug 23-25 | 35 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Shannon Timothy MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.1K | $85.95 | −$2.15M | −1.2%2.03M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Aug 26-30 | 32 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Shannon Timothy MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −115.6K | $85.72 | −$9.91M | −5.7%1.91M after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Aug 31-Sep 2 | 27 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Shannon Timothy MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −190.6K | $86.26 | −$16.4M | −10.0%1.72M after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 27, 2021 (view filing) | Sep 3-7 | 24 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Shannon Timothy MDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −68.8K | $87.42 | −$6.01M | −4.0%1.65M after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 3, 2021 (view filing) | Nov 1 | 2 days | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −40.0K | $88.14 | −$3.53M | −4.6%832.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 9, 2021 (view filing) | Nov 5 | 4 days | Ratcliffe LiamDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.9K | $91.30 | −$2.28M | −100.0%0 after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 9, 2021 (view filing) | Nov 5-9 | 4 days | Ratcliffe LiamDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −147.2K | $93.31 | −$13.7M | −17.9%675.7K after | 12 lotsThis row combines 12 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 15, 2021 (view filing) | Nov 10-15 | 5 days | Ratcliffe LiamDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −134.3K | $85.83 | −$11.5M | −19.9%541.4K after | 13 lotsThis row combines 13 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 17, 2021 (view filing) | Nov 15 | 2 days | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $84.04 | −$1.68M | −20.3%78.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 16, 2021 (view filing) | Dec 14-16 | 2 days | Ratcliffe LiamDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −355.7K | $67.00 | −$23.8M | −65.7%185.7K after | 8 lotsThis row combines 8 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 21, 2021 (view filing) | Dec 17 | 4 days | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $70.00 | −$1.05M | −8.7%158.2K after | |
| Jan 4, 2022 (view filing) | Dec 30, 2021 | 5 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $80.61 | −$1.61M | −78.7%5.40K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 19, 2022 (view filing) | Jan 14 | 5 days | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.0K | $65.55 | −$1.37M | −45.9%24.7K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 17, 2022 (view filing) | Feb 15 | 2 days | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $73.02 | −$1.46M | −20.3%78.6K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 4, 2022 (view filing) | Mar 4 | Same day | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.02K | $63.94 | −$385.2K | −0.7%843.8K after | |
| Mar 4, 2022 (view filing) | Mar 4 | Same day | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.59K | $63.94 | −$101.9K | −1.0%161.4K after | |
| Mar 4, 2022 (view filing) | Mar 4 | Same day | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −869 | $63.94 | −$55.6K | −1.0%84.0K after | |
| Mar 15, 2022 (view filing) | Mar 11 | 4 days | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $70.00 | −$1.05M | −8.5%161.4K after | |
| Apr 18, 2022 (view filing) | Apr 14 | 4 days | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.0K | $66.44 | −$1.39M | −51.2%20.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 16, 2022 (view filing) | Aug 12 | 4 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.26K | $54.84 | −$69.0K | −13.4%8.15K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Mar 3, 2023 (view filing) | Mar 1 | 2 days | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.75K | $29.53 | −$51.5K | −0.9%183.6K after | |
| Mar 3, 2023 (view filing) | Mar 1 | 2 days | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.88K | $29.53 | −$173.6K | −0.6%917.4K after | |
| Mar 3, 2023 (view filing) | Mar 1 | 2 days | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.05K | $29.53 | −$31.0K | −1.0%101.7K after | |
| Aug 14, 2023 (view filing) | Aug 11 | 3 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.32K | $24.39 | −$32.3K | −4.2%30.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 27, 2024 (view filing) | Feb 23 | 4 days | Taylor IanChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.70K | $47.05 | −$80.0K | −1.1%147.5K after | |
| Feb 27, 2024 (view filing) | Feb 23 | 4 days | Peck RonaldChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.70K | $47.05 | −$79.9K | −2.5%67.5K after | |
| Feb 27, 2024 (view filing) | Feb 23 | 4 days | Cassidy Sean AChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.70K | $47.05 | −$80.1K | −0.9%181.9K after | |
| Feb 27, 2024 (view filing) | Feb 23 | 4 days | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.20K | $47.05 | −$244.5K | −0.5%1.04M after | |
| Nov 12, 2024 (view filing) | Nov 8, 2023-Nov 7, 2024 | 370 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Loomis David KChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −460 | $22.39 | −$10.3K | −5.4%8.04K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 25, 2025 (view filing) | Feb 24 | 1 day | Houston John GPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.3K | $16.72 | −$523.9K | −2.6%1.16M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 25, 2025 (view filing) | Feb 24 | 1 day | Taylor IanPresident, R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.02K | $16.71 | −$150.8K | −5.4%159.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 25, 2025 (view filing) | Feb 24 | 1 day | Cacace Angela MChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.21K | $16.70 | −$70.2K | −4.1%97.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 25, 2025 (view filing) | Feb 24 | 1 day | Loomis David KChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.21K | $16.75 | −$20.3K | −6.0%18.9K after | |
| Mar 19, 2025 (view filing) | Mar 18 | 1 day | Berkowitz NoahChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.66K | $8.59 | −$74.4K | −7.3%110.0K after | |
| Jun 18, 2025 (view filing) | Jun 17 | 1 day | Cacace Angela MChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.58K | $7.49 | −$19.3K | −1.6%154.2K after | |
| Jun 24, 2025 (view filing) | Jun 24 | Same day | Saik AndrewChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.70K | $7.61 | −$43.4K | −3.4%164.4K after | |
| Sep 24, 2025 (view filing) | Sep 22 | 2 days | Morrison BriggsDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +30.0K | $7.57 | +$227.1K | +65.2%76.0K after | |
| Nov 7, 2025 (view filing) | Nov 7 | Same day | Loomis David KChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −230 | $9.89 | −$2.27K | −0.7%31.7K after | |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Loomis David KChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.02K | $11.89 | −$12.1K | −3.2%30.8K after | |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Berkowitz NoahChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.68K | $11.89 | −$67.6K | −3.4%163.9K after | |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Cacace Angela MChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.59K | $11.89 | −$54.6K | −2.9%151.2K after | |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Saik AndrewChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.13K | $11.89 | −$61.0K | −3.1%159.3K after | |
| Feb 18, 2026 (view filing) | Feb 13 | 5 days | Teel RandyPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.40K | $11.89 | −$52.4K | −2.8%154.5K after | |
