Annovis Bio, Inc.
ANVS- Exchange
- NYSE
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001477845
No open-market purchases or sales by Annovis Bio, Inc. insiders were filed in the last 90 days; 61 institutions reported holding it in 13F filings for Q2 2026, worth $20.2M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Annovis Bio, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 53
- +12 vs. Q3 2025
- Shares held
- 4.24M
- +2.24M (+112.4%) vs. Q3 2025
- Total value
- $14.7M
- +$10.5M (+255.1%) vs. Q3 2025
- New holders
- 20
- 17 more added
- Sold out
- 8
- 2 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANVS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 61 | $20.2M |
| Q1 2026 | 56 | $10.5M |
| Q4 2025 | 53 | $14.7M |
| Q3 2025 | 42 | $4.19M |
| Q2 2025 | 42 | $3.93M |
| Q1 2025 | 44 | $3.13M |
| Q4 2024 | 40 | $7.93M |
| Q3 2024 | 35 | $9.50M |
| Q2 2024 | 31 | $5.67M |
| Q1 2024 | 31 | $14.3M |
| Q4 2023 | 36 | $22.5M |
| Q3 2023 | 30 | $10.6M |
| Q2 2023 | 28 | $18.3M |
| Q1 2023 | 23 | $11.6M |
| Q4 2022 | 23 | $9.93M |
| Q3 2022 | 25 | $10.0M |
| Q2 2022 | 26 | $8.73M |
| Q1 2022 | 24 | $11.9M |
| Q4 2021 | 32 | $19.6M |
| Q3 2021 | 38 | $36.2M |
| Q2 2021 | 57 | $109.0M |
| Q1 2021 | 31 | $23.1M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Annovis Bio, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 923,201 | $3.19M | 0.00% | +185,198+25.1% | Added |
| Marshall Wace, LLP | 725,862 | $2.51M | 0.00% | +725,862 | New |
| Two Sigma Investments, LP | 551,837 | $1.91M | 0.00% | +551,837 | New |
| Susquehanna International Group, LLP | 303,287 | $1.05M | 0.00% | +84,866+38.9% | Added |
| Jane Street Group, LLC | 251,157 | $869.0K | 0.00% | +251,157 | New |
| Geode Capital Management, LLC | 222,132 | $768.7K | 0.00% | +37,978+20.6% | Added |
| D.A. Davidson & Co. | 160,779 | $556.3K | 0.00% | +160,779 | New |
| BlackRock, Inc. | 139,533 | $482.8K | 0.00% | +58,858+73.0% | Added |
| Northern Trust Corp | 120,862 | $418.2K | 0.00% | −198−0.2% | Reduced |
| Merit Financial Group, LLC | 81,316 | $281.4K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 74,035 | $256.2K | 0.00% | +35,600+92.6% | Added |
| Group One Trading, L.P. | 69,126 | $239.2K | 0.01% | +34,499+99.6% | Added |
| Omers Administration Corp | 62,100 | $214.9K | 0.00% | +62,100 | New |
| Two Sigma Advisers, LP | 45,221 | $156.5K | 0.00% | +45,221 | New |
| Greenwich Wealth Management LLC | 42,400 | $147.0K | 0.01% | −5,000−10.5% | Reduced |
| Wescott Financial Advisory Group, LLC | 41,607 | $144.0K | 0.01% | 00.0% | Unchanged |
| First National Trust Co | 40,000 | $138.4K | 0.00% | +25,000+166.7% | Added |
| UBS Group AG | 30,643 | $106.0K | 0.00% | +30,010+4,740.9% | Added |
| Sherry Group, Inc. | 27,270 | $94.4K | 0.10% | +27,270 | New |
| Virtu Financial LLC | 26,333 | $91.0K | 0.00% | +26,333 | New |
| Dakota Wealth Management | 26,200 | $90.7K | 0.00% | +26,200 | New |
| Bridgeway Capital Management, LLC | 24,400 | $84.4K | 0.00% | +5,000+25.8% | Added |
| Sterling Investment Advisors, Ltd. | 23,416 | $81.0K | 0.01% | 00.0% | Unchanged |
| GWM Advisors LLC | 20,500 | $70.9K | 0.00% | +20,500 | New |
| Bank of New York Mellon Corp | 20,058 | $69.4K | 0.00% | +1,000+5.2% | Added |
| Wealthspire Advisors, LLC | 20,000 | $69.2K | 0.00% | +10,000+100.0% | Added |
| Gill Capital Partners, LLC | 18,579 | $64.3K | 0.02% | +18,579 | New |
| Robertson Stephens Wealth Management, LLC | 18,579 | $64.3K | 0.00% | +18,579 | New |
| CWA Asset Management Group, LLC | 17,001 | $58.8K | 0.00% | +4,000+30.8% | Added |
| Koshinski Asset Management, Inc. | 15,010 | $51.9K | 0.00% | +15,010 | New |
| JPMorgan Chase & Co | 14,900 | $51.6K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 14,307 | $49.5K | 0.00% | +4,561+46.8% | Added |
| Tower Research Capital LLC (TRC) | 13,662 | $47.3K | 0.00% | +12,641+1,238.1% | Added |
| RFG Advisory, LLC | 12,461 | $43.1K | 0.00% | +12,461 | New |
| RKL Wealth Management LLC | 10,000 | $34.6K | 0.00% | +10,000 | New |
| Morgan Stanley | 9,901 | $34.3K | 0.00% | +2,512+34.0% | Added |
| Bryn Mawr Trust Co | 9,393 | $32.5K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 2,339 | $8.00K | 0.00% | 00.0% | Unchanged |
| FNY Investment Advisers, LLC | 2,000 | $6.00K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 1,527 | $5.28K | 0.00% | +96+6.7% | Added |
| DiNuzzo Private Wealth, Inc. | 1,000 | $3.46K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 1,000 | $3.46K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 1,000 | $3.46K | 0.00% | +1,000 | New |
| The PNC Financial Services Group, Inc. | 360 | $1.25K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 350 | $1.21K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 300 | $1.04K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 314 | $1.00K | 0.00% | +314 | New |
| IFP Advisors, Inc | 210 | $727 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 210 | $727 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 207 | $716 | 0.00% | +62+42.8% | Added |
| Global Retirement Partners, LLC | 100 | $346 | 0.00% | +100 | New |
| Citigroup Inc | 1 | $3 | 0.00% | +1 | New |
| Avion Wealth | 229 | $0 | 0.00% | +229 | New |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −174,345−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −37,579−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −28,854−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −10,511−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −4,091−100.0% | Sold out |
| Steward Partners Investment Advisory, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Bokf, NA | 0 | $0 | 0.00% | −555−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −333−100.0% | Sold out |
| Lokken Investment Group LLC | – | – | – | – | Not filed |