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Alx Oncology Holdings Inc

ALXO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001810182

In the last 90 days, Alx Oncology Holdings Inc insiders filed 0 open-market purchases and 3 sales; 93 institutions reported holding it in 13F filings for Q2 2026, worth $217.9M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alx Oncology Holdings Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
57
−2 vs. Q3 2025
Shares held
29.2M
+1.44M (+5.2%) vs. Q3 2025
Total value
$33.0M
−$17.8M (−35.0%) vs. Q3 2025
New holders
8
18 more added
Sold out
10
15 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALXO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 57 institutions
Q1 2021: 94 institutionsQ2 2021: 105 institutionsQ3 2021: 115 institutionsQ4 2021: 108 institutionsQ1 2022: 96 institutionsQ2 2022: 97 institutionsQ3 2022: 99 institutionsQ4 2022: 87 institutionsQ1 2023: 86 institutionsQ2 2023: 75 institutionsQ3 2023: 76 institutionsQ4 2023: 93 institutionsQ1 2024: 106 institutionsQ2 2024: 112 institutionsQ3 2024: 92 institutionsQ4 2024: 87 institutionsQ1 2025: 85 institutionsQ2 2025: 61 institutionsQ3 2025: 61 institutionsQ4 2025: 57 institutionsQ1 2026: 69 institutionsQ2 2026: 93 institutions
Value heldQ4 2025: $33.0M
Q1 2021: $2.47BQ2 2021: $1.82BQ3 2021: $2.55BQ4 2021: $780.0MQ1 2022: $621.9MQ2 2022: $290.7MQ3 2022: $348.7MQ4 2022: $410.6MQ1 2023: $161.4MQ2 2023: $257.5MQ3 2023: $159.8MQ4 2023: $681.5MQ1 2024: $510.5MQ2 2024: $293.4MQ3 2024: $82.7MQ4 2024: $68.5MQ1 2025: $21.7MQ2 2025: $12.1MQ3 2025: $50.8MQ4 2025: $33.0MQ1 2026: $189.0MQ2 2026: $217.9M
Institutions holding ALXO and their total value by quarter
QuarterHoldersValue
Q2 202693$217.9M
Q1 202669$189.0M
Q4 202557$33.0M
Q3 202561$50.8M
Q2 202561$12.1M
Q1 202585$21.7M
Q4 202487$68.5M
Q3 202492$82.7M
Q2 2024112$293.4M
Q1 2024106$510.5M
Q4 202393$681.5M
Q3 202376$159.8M
Q2 202375$257.5M
Q1 202386$161.4M
Q4 202287$410.6M
Q3 202299$348.7M
Q2 202297$290.7M
Q1 202296$621.9M
Q4 2021108$780.0M
Q3 2021115$2.55B
Q2 2021105$1.82B
Q1 202194$2.47B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alx Oncology Holdings Inc; share changes are against Q3 2025.

Institutions holding ALXO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
venBio Partners LLC9,699,925$11.0M5.07%00.0%Unchanged
Redmile Group, LLC3,264,718$3.69M0.27%−68,265−2.0%Reduced
Millennium Management LLC3,204,619$3.62M0.00%+581,758+22.2%Added
Almitas Capital LLC2,536,891$2.87M0.63%00.0%Unchanged
Vanguard Group Inc1,630,940$1.84M0.00%+102,321+6.7%Added
Driehaus Capital Management LLC1,422,882$1.61M0.01%+627,105+78.8%Added
Acadian Asset Management LLC1,374,273$1.55M0.00%+153,448+12.6%Added
UBS Group AG865,991$978.6K0.00%+693,421+401.8%Added
Two Sigma Advisers, LP710,400$802.8K0.00%−9,400−1.3%Reduced
Two Sigma Investments, LP640,205$723.4K0.00%+33,534+5.5%Added
Bank of America Corp531,845$601.0K0.00%+1,017+0.2%Added
Bank of Montreal474,781$536.5K0.00%00.0%Unchanged
BlackRock, Inc.450,430$509.0K0.00%+2,738+0.6%Added
Renaissance Technologies LLC423,099$478.1K0.00%+258,600+157.2%Added
Geode Capital Management, LLC353,696$399.8K0.00%+1,361+0.4%Added
Jane Street Group, LLC185,961$210.1K0.00%+5,545+3.1%Added
Susquehanna International Group, LLP151,027$170.7K0.00%+37,964+33.6%Added
Northern Trust Corp149,097$168.5K0.00%+53,937+56.7%Added
State Street Corp124,228$140.4K0.00%+12,300+11.0%Added
Seven Fleet Capital Management LP117,817$133.1K0.09%+117,817New
Bank of Nova Scotia105,858$119.6K0.00%00.0%Unchanged
Gsa Capital Partners LLP92,654$105.0K0.01%+4,489+5.1%Added
Ieq Capital, LLC92,233$104.2K0.00%00.0%Unchanged
Morgan Stanley83,757$94.6K0.00%−1,533−1.8%Reduced
Bridgeway Capital Management, LLC76,072$86.0K0.00%+40,072+111.3%Added
Citadel Advisors LLC56,732$64.1K0.00%+56,732New
Nan Fung Trinity (HK) Ltd41,950$47.4K0.00%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC37,992$41.0K0.00%−81−0.2%Reduced
Callan Family Office, LLC28,308$32.0K0.00%+8,530+43.1%Added
Marshall Wace, LLP26,376$29.8K0.00%−13,207−33.4%Reduced
HC Advisors, LLC23,900$27.0K0.02%+2,050+9.4%Added
Lido Advisors, LLC13,220$24.2K0.00%00.0%Unchanged
Point72 Asset Management, L.P.20,217$22.8K0.00%+20,217New
JSF Financial, LLC17,500$19.8K0.00%00.0%Unchanged
Goldman Sachs Group Inc17,262$19.5K0.00%−1,332−7.2%Reduced
Nine Masts Capital Ltd15,475$17.5K0.00%+15,475New
Moneta Group Investment Advisors LLC15,196$17.2K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC15,102$17.1K0.00%−5,470−26.6%Reduced
Virtu Financial LLC13,702$15.0K0.00%+13,702New
FMR LLC12,986$14.7K0.00%00.0%Unchanged
Abel Hall, LLC12,598$14.2K0.00%00.0%Unchanged
Barclays PLC10,515$11.9K0.00%−52−0.5%Reduced
HSBC Holdings PLC10,105$11.6K0.00%−712−6.6%Reduced
Simplex Trading, LLC3,553$4.01K0.00%+3,553New
Tower Research Capital LLC (TRC)3,142$3.55K0.00%−696−18.1%Reduced
Torren Management, LLC1,632$1.84K0.00%+1,632New
Nisa Investment Advisors, LLC1,106$1.25K0.00%00.0%Unchanged
Bradley & Co. Private Wealth Management, LLC1,000$1.13K0.00%00.0%Unchanged
Royal Bank of Canada963$1.00K0.00%−140−12.7%Reduced
Group One Trading, L.P.518$5850.00%+518New
BNP Paribas Arbitrage, SA480$5420.00%00.0%Unchanged
SBI Securities Co., Ltd.412$4660.00%−10−2.4%Reduced
The PNC Financial Services Group, Inc.100$1130.00%00.0%Unchanged
JPMorgan Chase & Co99$1120.00%−61,800−99.8%Reduced
Optiver Holding B.V.27$310.00%−1−3.6%Reduced
CWM, LLC96$00.00%−48−33.3%Reduced
DekaBank Deutsche Girozentrale41,000––00.0%Unchanged
Ameriprise Financial Inc0$00.00%−652,897−100.0%Sold out
Privium Fund Management B.V.0$00.00%−509,059−100.0%Sold out
XTX Topco Ltd0$00.00%−26,621−100.0%Sold out
HRT Financial LP0$00.00%−22,535−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−16,946−100.0%Sold out
AQR Capital Management LLC0$00.00%−10,793−100.0%Sold out
Federated Hermes, Inc.0$00.00%−2,374−100.0%Sold out
Citigroup Inc0$00.00%−2,278−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−499−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−2−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed