Alumis Inc.
ALMS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001847367
In the last 90 days, Alumis Inc. insiders filed 1 open-market purchase and 8 sales; 198 institutions reported holding it in 13F filings for Q2 2026, worth $3.32B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alumis Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 134
- +5 vs. Q3 2025
- Shares held
- 79.1M
- +2.48M (+3.2%) vs. Q3 2025
- Total value
- $771.1M
- +$465.5M (+152.3%) vs. Q3 2025
- New holders
- 30
- 48 more added
- Sold out
- 25
- 33 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALMS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 198 | $3.32B |
| Q1 2026 | 197 | $2.53B |
| Q4 2025 | 134 | $771.1M |
| Q3 2025 | 130 | $311.2M |
| Q2 2025 | 112 | $235.0M |
| Q1 2025 | 72 | $246.8M |
| Q4 2024 | 64 | $316.5M |
| Q3 2024 | 52 | $376.1M |
| Q2 2024 | 29 | $380.0M |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alumis Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| D. E. Shaw & Co., Inc. | 231,747 | $2.26M | 0.00% | +231,747 | New |
| Exome Asset Management LLC | 292,250 | $2.85M | 1.41% | −520−0.2% | Reduced |
| Two Sigma Investments, LP | 298,219 | $2.91M | 0.00% | +212,135+246.4% | Added |
| JPMorgan Chase & Co | 356,337 | $3.48M | 0.00% | +87,670+32.6% | Added |
| Marshall Wace, LLP | 372,901 | $3.64M | 0.00% | +372,901 | New |
| Northern Trust Corp | 418,248 | $4.08M | 0.00% | −20,724−4.7% | Reduced |
| Invesco Ltd. | 421,819 | $4.12M | 0.00% | +292,250+225.6% | Added |
| Goldman Sachs Group Inc | 427,072 | $4.17M | 0.00% | +9,992+2.4% | Added |
| Towerview LLC | 495,000 | $4.83M | 3.51% | 00.0% | Unchanged |
| Siren, L.L.C. | 500,000 | $4.88M | 0.15% | +500,000 | New |
| Charles Schwab Investment Management Inc | 504,075 | $4.92M | 0.00% | +13,073+2.7% | Added |
| Morgan Stanley | 506,529 | $4.94M | 0.00% | +174,123+52.4% | Added |
| Opaleye Management Inc. | 535,000 | $5.22M | 0.69% | −130,000−19.5% | Reduced |
| Omega Fund Management, LLC | 653,223 | $6.38M | 2.23% | 00.0% | Unchanged |
| Fan Yu | 789,618 | $7.71M | 8.35% | 00.0% | Unchanged |
| Trium Capital LLP | 893,107 | $8.72M | 6.77% | −2,229,004−71.4% | Reduced |
| OrbiMed Advisors LLC | 1,102,730 | $10.8M | 0.22% | −823,693−42.8% | Reduced |
| Millennium Management LLC | 1,151,118 | $11.2M | 0.01% | +834,089+263.1% | Added |
| State Street Corp | 1,259,446 | $12.3M | 0.00% | +157,560+14.3% | Added |
| Geode Capital Management, LLC | 1,487,626 | $14.5M | 0.00% | +94,340+6.8% | Added |
| Baker Bros. Advisors LP | 1,562,500 | $15.3M | 0.09% | 00.0% | Unchanged |
| Sr One Capital Management, LP | 1,959,896 | $19.1M | 2.71% | 00.0% | Unchanged |
| MPM Oncology Impact Management LP | 2,401,992 | $23.4M | 2.68% | +2,401,992 | New |
| Octagon Capital Advisors LP | 2,530,700 | $24.7M | 3.09% | +2,530,700 | New |
| Nextech Invest, Ltd. | 2,915,998 | $28.5M | 2.75% | 00.0% | Unchanged |
| Saturn V Capital Management LLC | 3,135,953 | $30.6M | 5.62% | +3,135,953 | New |
| Cormorant Asset Management, LP | 3,635,596 | $35.5M | 2.01% | +1,488,200+69.3% | Added |
| Vanguard Group Inc | 4,103,290 | $40.0M | 0.00% | +73,675+1.8% | Added |
| Foresite Capital Management VI LLC | 4,247,670 | $41.5M | 12.53% | 00.0% | Unchanged |
| BlackRock, Inc. | 4,566,502 | $44.6M | 0.00% | +373,425+8.9% | Added |
| venBio Partners LLC | 4,619,803 | $45.1M | 20.85% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 5,756,984 | $56.2M | 5.80% | +955,614+19.9% | Added |
| Foresite Capital Management V, LLC | 5,779,348 | $56.4M | 34.31% | 00.0% | Unchanged |
| AyurMaya Capital Management Company, LP | 15,139,706 | $147.8M | 100.00% | 00.0% | Unchanged |
| Woodline Partners LP | 0 | $0 | 0.00% | −1,751,150−100.0% | Sold out |
| General Atlantic LLC | 0 | $0 | 0.00% | −1,297,530−100.0% | Sold out |
| BML Capital Management, LLC | 0 | $0 | 0.00% | −1,210,415−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −1,167,009−100.0% | Sold out |
| Velan Capital Investment Management LP | 0 | $0 | 0.00% | −946,683−100.0% | Sold out |
| Madison Avenue Partners, LP | 0 | $0 | 0.00% | −417,777−100.0% | Sold out |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −300,000−100.0% | Sold out |
| Credit Industriel Et Commercial | 0 | $0 | 0.00% | −247,002−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −77,550−100.0% | Sold out |
| Blair William & Co | 0 | $0 | 0.00% | −66,719−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −61,291−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −40,162−100.0% | Sold out |
| Stoneridge Investment Partners LLC | 0 | $0 | 0.00% | −29,535−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −24,176−100.0% | Sold out |
| PharVision Advisers, LLC | 0 | $0 | 0.00% | −20,693−100.0% | Sold out |
| Sig Brokerage, LP | 0 | $0 | 0.00% | −19,808−100.0% | Sold out |
| Western Wealth Management, LLC | 0 | $0 | 0.00% | −12,035−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −8,837−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −3,938−100.0% | Sold out |
| GPS Wealth Strategies Group, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Clayton Financial Group LLC | 0 | $0 | 0.00% | −481−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −113−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −103−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −36−100.0% | Sold out |
| Salem Investment Counselors Inc | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Tybourne Capital Management (HK) Ltd | – | – | – | – | Not filed |