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Alector, Inc.

ALEC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001653087

In the last 90 days, Alector, Inc. insiders filed 0 open-market purchases and 3 sales; 140 institutions reported holding it in 13F filings for Q2 2026, worth $183.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alector, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
131
−14 vs. Q3 2025
Shares held
84.4M
+10.2M (+13.7%) vs. Q3 2025
Total value
$131.5M
−$88.3M (−40.2%) vs. Q3 2025
New holders
25
40 more added
Sold out
39
41 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALEC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 131 institutions
Q1 2021: 127 institutionsQ2 2021: 138 institutionsQ3 2021: 145 institutionsQ4 2021: 167 institutionsQ1 2022: 166 institutionsQ2 2022: 154 institutionsQ3 2022: 168 institutionsQ4 2022: 155 institutionsQ1 2023: 149 institutionsQ2 2023: 145 institutionsQ3 2023: 149 institutionsQ4 2023: 148 institutionsQ1 2024: 157 institutionsQ2 2024: 160 institutionsQ3 2024: 159 institutionsQ4 2024: 150 institutionsQ1 2025: 141 institutionsQ2 2025: 136 institutionsQ3 2025: 149 institutionsQ4 2025: 131 institutionsQ1 2026: 138 institutionsQ2 2026: 140 institutions
Value heldQ4 2025: $131.5M
Q1 2021: $931.7MQ2 2021: $1.02BQ3 2021: $1.19BQ4 2021: $1.13BQ1 2022: $789.8MQ2 2022: $546.8MQ3 2022: $516.1MQ4 2022: $506.0MQ1 2023: $360.9MQ2 2023: $354.5MQ3 2023: $402.6MQ4 2023: $510.1MQ1 2024: $446.6MQ2 2024: $330.4MQ3 2024: $338.4MQ4 2024: $138.8MQ1 2025: $89.1MQ2 2025: $98.7MQ3 2025: $221.2MQ4 2025: $131.5MQ1 2026: $190.0MQ2 2026: $183.4M
Institutions holding ALEC and their total value by quarter
QuarterHoldersValue
Q2 2026140$183.4M
Q1 2026138$190.0M
Q4 2025131$131.5M
Q3 2025149$221.2M
Q2 2025136$98.7M
Q1 2025141$89.1M
Q4 2024150$138.8M
Q3 2024159$338.4M
Q2 2024160$330.4M
Q1 2024157$446.6M
Q4 2023148$510.1M
Q3 2023149$402.6M
Q2 2023145$354.5M
Q1 2023149$360.9M
Q4 2022155$506.0M
Q3 2022168$516.1M
Q2 2022154$546.8M
Q1 2022166$789.8M
Q4 2021167$1.13B
Q3 2021145$1.19B
Q2 2021138$1.02B
Q1 2021127$931.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alector, Inc.; share changes are against Q3 2025.

Institutions holding ALEC in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Panagora Asset Management Inc850,298$1.33M0.00%+109,005+14.7%Added
Elmind Capital, LP900,000$1.40M0.41%+900,000New
DAFNA Capital Management LLC908,351$1.42M0.33%+110,000+13.8%Added
Jane Street Group, LLC993,913$1.55M0.00%+643,682+183.8%Added
Eversept Partners, LP1,006,163$1.57M0.09%−482,562−32.4%Reduced
Deutsche Bank AG1,035,154$1.61M0.00%−33,061−3.1%Reduced
Two Sigma Investments, LP1,039,656$1.62M0.00%+732,477+238.5%Added
Deerfield Management Company, L.P. (Series C)1,055,192$1.65M0.02%00.0%Unchanged
ADAR1 Capital Management, LLC1,108,000$1.73M0.13%+1,108,000New
Spruce Street Capital LP1,117,986$1.74M0.58%+1,117,986New
Marshall Wace, LLP1,166,817$1.82M0.00%+1,015,174+669.4%Added
Euclidean Capital LLC1,307,858$2.04M0.55%00.0%Unchanged
Millennium Management LLC1,332,914$2.08M0.00%+177,887+15.4%Added
Medici Capital LLC1,500,520$2.34M2.57%+1,018,546+211.3%Added
Renaissance Technologies LLC1,543,650$2.41M0.00%+594,500+62.6%Added
State Street Corp1,814,298$2.83M0.00%+79,619+4.6%Added
Kynam Capital Management, LP2,000,000$3.12M0.20%+2,000,000New
Geode Capital Management, LLC2,075,220$3.24M0.00%+213,962+11.5%Added
Ikarian Capital, LLC2,082,606$3.25M0.42%+1,322,606+174.0%Added
Jacobs Levy Equity Management, Inc2,173,202$3.39M0.01%+942,228+76.5%Added
FMR LLC2,231,171$3.48M0.00%−12,950,678−85.3%Reduced
D. E. Shaw & Co., Inc.2,365,151$3.69M0.00%+1,386,947+141.8%Added
Balyasny Asset Management LLC3,265,575$5.09M0.01%+3,265,575New
683 Capital Management, LLC3,350,000$5.23M0.43%+2,350,000+235.0%Added
Acadian Asset Management LLC3,442,449$5.36M0.01%+1,069,464+45.1%Added
Merck & Co., Inc.3,545,719$5.53M2.00%00.0%Unchanged
Foresite Capital Management IV, LLC3,887,200$6.06M2.64%+3,887,200New
Vanguard Group Inc6,908,054$10.8M0.00%+873,395+14.5%Added
BlackRock, Inc.7,147,766$11.2M0.00%−50,207−0.7%Reduced
TCG Crossover Management, LLC10,000,000$15.6M0.52%+10,000,000New
DekaBank Deutsche Girozentrale100,000––00.0%Unchanged
RTW Investments, LP0$00.00%−6,990,806−100.0%Sold out
5AM Venture Management, LLC0$00.00%−995,841−100.0%Sold out
TD Asset Management Inc0$00.00%−273,738−100.0%Sold out
Alphabet Inc.0$00.00%−175,866−100.0%Sold out
Diadema Partners LP0$00.00%−136,023−100.0%Sold out
Artia Global Partners LP0$00.00%−71,029−100.0%Sold out
Velan Capital Investment Management LP0$00.00%−55,000−100.0%Sold out
Ieq Capital, LLC0$00.00%−53,050−100.0%Sold out
Bank of Montreal0$00.00%−52,380−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−31,240−100.0%Sold out
MetLife Investment Management0$00.00%−28,820−100.0%Sold out
Apollon Wealth Management, LLC0$00.00%−25,000−100.0%Sold out
Group One Trading, L.P.0$00.00%−22,321−100.0%Sold out
American Century Companies Inc0$00.00%−20,481−100.0%Sold out
Erste Asset Management GmbH0$00.00%−19,000−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−17,741−100.0%Sold out
Creative Planning0$00.00%−15,721−100.0%Sold out
DLK Investment Management, LLC0$00.00%−15,500−100.0%Sold out
FNY Investment Advisers, LLC0$00.00%−15,000−100.0%Sold out
Engineers Gate Manager LP0$00.00%−14,493−100.0%Sold out
Hamilton Lane Advisors LLC0$00.00%−14,402−100.0%Sold out
Wealth Enhancement Advisory Services, LLC0$00.00%−11,970−100.0%Sold out
Belvedere Trading LLC0$00.00%−10,486−100.0%Sold out
SVB Capital Management, LLC0$00.00%−10,286−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−3,913−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−3,190−100.0%Sold out
GF Fund Management Co. Ltd.0$00.00%−2,178−100.0%Sold out
Optiver Holding B.V.0$00.00%−1,018−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−453−100.0%Sold out
Fortitude Family Office, LLC0$00.00%−439−100.0%Sold out
Rise Advisors, LLC0$00.00%−407−100.0%Sold out
Rialto Wealth Management, LLC0$00.00%−403−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−370−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−277−100.0%Sold out
Advisory Services Network, LLC0$00.00%−271−100.0%Sold out
Allworth Financial LP0$00.00%−84−100.0%Sold out
GWM Advisors LLC0$00.00%−32−100.0%Sold out
Truvestments Capital LLC0$00.00%−2−100.0%Sold out
Avion Wealth0$00.00%−336−100.0%Sold out
New Leaf Venture Partners, L.L.C.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed