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Alector, Inc.

ALEC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001653087

In the last 90 days, Alector, Inc. insiders filed 0 open-market purchases and 3 sales; 140 institutions reported holding it in 13F filings for Q2 2026, worth $183.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alector, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
131
−14 vs. Q3 2025
Shares held
84.4M
+10.2M (+13.7%) vs. Q3 2025
Total value
$131.5M
−$88.3M (−40.2%) vs. Q3 2025
New holders
25
40 more added
Sold out
39
41 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALEC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 131 institutions
Q1 2021: 127 institutionsQ2 2021: 138 institutionsQ3 2021: 145 institutionsQ4 2021: 167 institutionsQ1 2022: 166 institutionsQ2 2022: 154 institutionsQ3 2022: 168 institutionsQ4 2022: 155 institutionsQ1 2023: 149 institutionsQ2 2023: 145 institutionsQ3 2023: 149 institutionsQ4 2023: 148 institutionsQ1 2024: 157 institutionsQ2 2024: 160 institutionsQ3 2024: 159 institutionsQ4 2024: 150 institutionsQ1 2025: 141 institutionsQ2 2025: 136 institutionsQ3 2025: 149 institutionsQ4 2025: 131 institutionsQ1 2026: 138 institutionsQ2 2026: 140 institutions
Value heldQ4 2025: $131.5M
Q1 2021: $931.7MQ2 2021: $1.02BQ3 2021: $1.19BQ4 2021: $1.13BQ1 2022: $789.8MQ2 2022: $546.8MQ3 2022: $516.1MQ4 2022: $506.0MQ1 2023: $360.9MQ2 2023: $354.5MQ3 2023: $402.6MQ4 2023: $510.1MQ1 2024: $446.6MQ2 2024: $330.4MQ3 2024: $338.4MQ4 2024: $138.8MQ1 2025: $89.1MQ2 2025: $98.7MQ3 2025: $221.2MQ4 2025: $131.5MQ1 2026: $190.0MQ2 2026: $183.4M
Institutions holding ALEC and their total value by quarter
QuarterHoldersValue
Q2 2026140$183.4M
Q1 2026138$190.0M
Q4 2025131$131.5M
Q3 2025149$221.2M
Q2 2025136$98.7M
Q1 2025141$89.1M
Q4 2024150$138.8M
Q3 2024159$338.4M
Q2 2024160$330.4M
Q1 2024157$446.6M
Q4 2023148$510.1M
Q3 2023149$402.6M
Q2 2023145$354.5M
Q1 2023149$360.9M
Q4 2022155$506.0M
Q3 2022168$516.1M
Q2 2022154$546.8M
Q1 2022166$789.8M
Q4 2021167$1.13B
Q3 2021145$1.19B
Q2 2021138$1.02B
Q1 2021127$931.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alector, Inc.; share changes are against Q3 2025.

Institutions holding ALEC in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC10,000,000$15.6M0.52%+10,000,000New
BlackRock, Inc.7,147,766$11.2M0.00%−50,207−0.7%Reduced
Vanguard Group Inc6,908,054$10.8M0.00%+873,395+14.5%Added
Foresite Capital Management IV, LLC3,887,200$6.06M2.64%+3,887,200New
Merck & Co., Inc.3,545,719$5.53M2.00%00.0%Unchanged
Acadian Asset Management LLC3,442,449$5.36M0.01%+1,069,464+45.1%Added
683 Capital Management, LLC3,350,000$5.23M0.43%+2,350,000+235.0%Added
Balyasny Asset Management LLC3,265,575$5.09M0.01%+3,265,575New
D. E. Shaw & Co., Inc.2,365,151$3.69M0.00%+1,386,947+141.8%Added
FMR LLC2,231,171$3.48M0.00%−12,950,678−85.3%Reduced
Jacobs Levy Equity Management, Inc2,173,202$3.39M0.01%+942,228+76.5%Added
Ikarian Capital, LLC2,082,606$3.25M0.42%+1,322,606+174.0%Added
Geode Capital Management, LLC2,075,220$3.24M0.00%+213,962+11.5%Added
Kynam Capital Management, LP2,000,000$3.12M0.20%+2,000,000New
State Street Corp1,814,298$2.83M0.00%+79,619+4.6%Added
Renaissance Technologies LLC1,543,650$2.41M0.00%+594,500+62.6%Added
Medici Capital LLC1,500,520$2.34M2.57%+1,018,546+211.3%Added
Millennium Management LLC1,332,914$2.08M0.00%+177,887+15.4%Added
Euclidean Capital LLC1,307,858$2.04M0.55%00.0%Unchanged
Marshall Wace, LLP1,166,817$1.82M0.00%+1,015,174+669.4%Added
Spruce Street Capital LP1,117,986$1.74M0.58%+1,117,986New
ADAR1 Capital Management, LLC1,108,000$1.73M0.13%+1,108,000New
Deerfield Management Company, L.P. (Series C)1,055,192$1.65M0.02%00.0%Unchanged
Two Sigma Investments, LP1,039,656$1.62M0.00%+732,477+238.5%Added
Deutsche Bank AG1,035,154$1.61M0.00%−33,061−3.1%Reduced
Eversept Partners, LP1,006,163$1.57M0.09%−482,562−32.4%Reduced
Jane Street Group, LLC993,913$1.55M0.00%+643,682+183.8%Added
DAFNA Capital Management LLC908,351$1.42M0.33%+110,000+13.8%Added
Elmind Capital, LP900,000$1.40M0.41%+900,000New
Panagora Asset Management Inc850,298$1.33M0.00%+109,005+14.7%Added
Vestal Point Capital, LP755,000$1.18M0.04%−225,000−23.0%Reduced
Charles Schwab Investment Management Inc665,491$1.04M0.00%−24,033−3.5%Reduced
Two Sigma Advisers, LP651,800$1.02M0.00%+134,400+26.0%Added
Mackenzie Financial Corp660,168$1.00M0.00%+376,456+132.7%Added
AQR Capital Management LLC599,569$935.3K0.00%+161,482+36.9%Added
XTX Topco Ltd592,839$924.8K0.02%+494,326+501.8%Added
Northern Trust Corp587,653$916.7K0.00%−46,056−7.3%Reduced
Boothbay Fund Management, LLC559,726$873.2K0.02%+35,649+6.8%Added
Goldman Sachs Group Inc437,959$683.2K0.00%−171,950−28.2%Reduced
Barclays PLC398,687$622.0K0.00%−474,688−54.4%Reduced
Ameriprise Financial Inc354,299$552.7K0.00%+80,257+29.3%Added
Morgan Stanley319,072$497.8K0.00%−115,096−26.5%Reduced
Susquehanna International Group, LLP291,180$454.2K0.00%−17,480−5.7%Reduced
Invesco Ltd.279,468$436.0K0.00%+87,157+45.3%Added
Gsa Capital Partners LLP225,566$352.0K0.03%+225,566New
Bank of New York Mellon Corp217,862$339.9K0.00%−6,622−2.9%Reduced
Nano Cap New Millennium Growth Fund L P200,000$312.0K0.27%+200,000New
Dimensional Fund Advisors LP199,126$310.5K0.00%−96,720−32.7%Reduced
Canada Pension Plan Investment Board172,300$268.8K0.00%+172,300New
Public Employees Retirement System of Ohio136,000$212.2K0.00%+67,800+99.4%Added
Bank of America Corp134,506$209.8K0.00%−111,777−45.4%Reduced
Utah Retirement Systems133,718$208.6K0.00%+61,716+85.7%Added
Nuveen, LLC133,248$207.9K0.00%00.0%Unchanged
UBS Group AG119,411$186.3K0.00%−111,088−48.2%Reduced
Bridgeway Capital Management, LLC115,000$179.4K0.00%00.0%Unchanged
STRS Ohio110,400$172.2K0.00%00.0%Unchanged
Graham Capital Management, L.P.104,851$163.6K0.01%+83,636+394.2%Added
Rhumbline Advisers101,926$159.0K0.00%−12,344−10.8%Reduced
Jasper Ridge Partners, L.P.95,068$148.3K0.00%+23,292+32.5%Added
Citadel Advisors LLC93,547$145.9K0.00%−378,034−80.2%Reduced
Alliancebernstein L.P.92,940$145.0K0.00%00.0%Unchanged
Los Angeles Capital Management LLC93,052$141.4K0.00%+1,816+2.0%Added
Wells Fargo & Company90,108$140.6K0.00%+37,683+71.9%Added
Man Group plc86,162$134.4K0.00%+86,162New
Simplex Trading, LLC82,017$127.9K0.00%−18,927−18.8%Reduced
Squarepoint Ops LLC77,618$121.1K0.00%+77,618New
Russell Investments Group, Ltd.71,887$112.1K0.00%−32,937−31.4%Reduced
Blackstone Group Inc.66,859$104.3K0.00%+41,144+160.0%Added
Quadrature Capital Ltd62,273$97.1K0.00%+62,273New
Price T Rowe Associates Inc56,203$89.0K0.00%−2,128,829−97.4%Reduced
HRT Financial LP57,341$89.0K0.00%−2,823−4.7%Reduced
Spears Abacus Advisors LLC54,642$85.2K0.00%−4,581−7.7%Reduced
Lexington Partners L.P.53,488$83.4K0.02%+43,380+429.2%Added
JustInvest LLC53,056$82.8K0.00%−5,264−9.0%Reduced
HSBC Holdings PLC48,521$75.7K0.00%−145−0.3%Reduced
Oxford Asset Management LLP42,905$66.9K0.02%+42,905New
Tudor Investment Corp Et Al41,282$64.4K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)39,520$61.7K0.00%+37,006+1,472.0%Added
Mirae Asset Global ETFs Holdings Ltd.37,271$58.1K0.00%+5,142+16.0%Added
Intech Investment Management LLC34,510$53.8K0.00%+1,082+3.2%Added
JPMorgan Chase & Co32,623$50.9K0.00%−103,762−76.1%Reduced
Prudential Financial Inc32,225$50.3K0.00%+4,203+15.0%Added
Vontobel Holding Ltd.30,000$46.8K0.00%+4,000+15.4%Added
Manufacturers Life Insurance Company, The28,829$45.0K0.00%−187,745−86.7%Reduced
SG Americas Securities, LLC27,002$42.0K0.00%+27,002New
Dynamic Technology Lab Private Ltd25,881$40.0K0.01%+25,881New
Police & Firemen's Retirement System of New Jersey23,426$36.5K0.00%00.0%Unchanged
Point72 Asset Management, L.P.23,102$36.0K0.00%+22,560+4,162.4%Added
BNP Paribas Arbitrage, SA22,385$34.9K0.00%+4,116+22.5%Added
Virtu Financial LLC21,886$34.0K0.00%+21,886New
Hershey Trust Co20,572$32.1K0.00%+10,286+100.0%Added
Bronte Capital Management Pty Ltd.19,282$30.1K0.00%+19,282New
SEI Investments Co16,884$26.3K0.00%00.0%Unchanged
ProShare Advisors LLC14,672$22.9K0.00%−759−4.9%Reduced
Neuberger Berman Group LLC14,173$22.1K0.00%+14,173New
Diversified Trust Co14,102$22.0K0.00%00.0%Unchanged
Voya Investment Management LLC13,929$21.7K0.00%00.0%Unchanged
Cerity Partners LLC13,682$21.3K0.00%−13,125−49.0%Reduced
R Squared Ltd12,474$19.5K0.01%+12,474New
CWM, LLC12,164$19.0K0.00%−13,005−51.7%Reduced