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AC Immune SA

ACIU
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001651625

No open-market purchases or sales by AC Immune SA insiders were filed in the last 90 days; 43 institutions reported holding it in 13F filings for Q2 2026, worth $58.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in AC Immune SA as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
42
+2 vs. Q3 2025
Shares held
25.9M
+1.25M (+5.1%) vs. Q3 2025
Total value
$81.2M
+$10.1M (+14.2%) vs. Q3 2025
New holders
8
15 more added
Sold out
6
10 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ACIU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 42 institutions
Q1 2021: 51 institutionsQ2 2021: 57 institutionsQ3 2021: 64 institutionsQ4 2021: 44 institutionsQ1 2022: 36 institutionsQ2 2022: 35 institutionsQ3 2022: 34 institutionsQ4 2022: 37 institutionsQ1 2023: 34 institutionsQ2 2023: 31 institutionsQ3 2023: 28 institutionsQ4 2023: 32 institutionsQ1 2024: 37 institutionsQ2 2024: 45 institutionsQ3 2024: 43 institutionsQ4 2024: 45 institutionsQ1 2025: 41 institutionsQ2 2025: 42 institutionsQ3 2025: 40 institutionsQ4 2025: 42 institutionsQ1 2026: 47 institutionsQ2 2026: 43 institutions
Value heldQ4 2025: $81.2M
Q1 2021: $138.5MQ2 2021: $144.3MQ3 2021: $118.5MQ4 2021: $74.5MQ1 2022: $57.2MQ2 2022: $49.8MQ3 2022: $44.3MQ4 2022: $30.1MQ1 2023: $33.0MQ2 2023: $47.4MQ3 2023: $45.5MQ4 2023: $148.2MQ1 2024: $85.7MQ2 2024: $114.0MQ3 2024: $106.6MQ4 2024: $73.9MQ1 2025: $48.5MQ2 2025: $49.7MQ3 2025: $71.1MQ4 2025: $81.2MQ1 2026: $69.2MQ2 2026: $58.2M
Institutions holding ACIU and their total value by quarter
QuarterHoldersValue
Q2 202643$58.2M
Q1 202647$69.2M
Q4 202542$81.2M
Q3 202540$71.1M
Q2 202542$49.7M
Q1 202541$48.5M
Q4 202445$73.9M
Q3 202443$106.6M
Q2 202445$114.0M
Q1 202437$85.7M
Q4 202332$148.2M
Q3 202328$45.5M
Q2 202331$47.4M
Q1 202334$33.0M
Q4 202237$30.1M
Q3 202234$44.3M
Q2 202235$49.8M
Q1 202236$57.2M
Q4 202144$74.5M
Q3 202164$118.5M
Q2 202157$144.3M
Q1 202151$138.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding AC Immune SA; share changes are against Q3 2025.

Institutions holding ACIU in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc19,822,436$62.2M2.10%00.0%Unchanged
Wells Fargo & Company1,006,289$3.16M0.00%−4,232−0.4%Reduced
Millennium Management LLC933,342$2.93M0.00%+38,810+4.3%Added
Renaissance Technologies LLC668,867$2.10M0.00%−101,552−13.2%Reduced
BlackRock, Inc.502,169$1.58M0.00%+90,321+21.9%Added
Acadian Asset Management LLC464,697$1.44M0.00%+51,460+12.5%Added
Point72 Asset Management, L.P.384,845$1.21M0.00%+384,845New
Arrowstreet Capital, Limited Partnership375,623$1.18M0.00%+375,623New
Northern Trust Corp281,953$885.3K0.00%00.0%Unchanged
Dimensional Fund Advisors LP213,464$670.4K0.00%+36,353+20.5%Added
UBS Group AG194,349$610.3K0.00%+177,925+1,083.3%Added
Marshall Wace, LLP186,709$586.3K0.00%+186,709New
Susquehanna International Group, LLP147,625$463.5K0.00%+125,785+575.9%Added
Dauntless Investment Group, LLC115,677$363.2K1.34%+115,677New
Deeter Investments LLP100,000$314.0K0.07%+100,000New
Morgan Stanley94,345$296.2K0.00%+2,312+2.5%Added
Two Sigma Investments, LP87,884$276.0K0.00%+71,109+423.9%Added
Citadel Advisors LLC71,151$223.4K0.00%+51,038+253.8%Added
Geode Capital Management, LLC63,601$199.7K0.00%00.0%Unchanged
Bank of America Corp21,471$67.4K0.00%+15,555+262.9%Added
Goldman Sachs Group Inc18,555$58.3K0.00%+5,920+46.9%Added
China Universal Asset Management Co., Ltd.16,362$51.4K0.00%−1,238−7.0%Reduced
SEI Investments Co15,884$49.9K0.00%00.0%Unchanged
EFG International AG12,900$40.5K0.00%+12,900New
Jane Street Group, LLC10,710$33.6K0.00%+10,710New
Quinn Opportunity Partners LLC10,100$31.7K0.00%00.0%Unchanged
Silverberg Bernstein Capital Management LLC10,000$31.3K0.02%00.0%Unchanged
JPMorgan Chase & Co8,721$27.4K0.00%+1,462+20.1%Added
Banque Cantonale Vaudoise7,892$25.0K0.00%−10,548−57.2%Reduced
Tower Research Capital LLC (TRC)6,166$19.4K0.00%+2,860+86.5%Added
Mirae Asset Global Investments Co., Ltd.4,879$15.3K0.00%+997+25.7%Added
Leonteq Securities AG3,000$9.42K0.00%+3,000New
Citigroup Inc2,801$8.79K0.00%+870+45.1%Added
Barclays PLC2,701$8.48K0.00%−2,589−48.9%Reduced
BNP Paribas Arbitrage, SA2,480$7.79K0.00%−323−11.5%Reduced
GF Fund Management Co. Ltd.1,972$6.19K0.00%−188−8.7%Reduced
Rockefeller Capital Management L.P.1,000$3.14K0.00%00.0%Unchanged
Activest Wealth Management1,000$3.14K0.00%00.0%Unchanged
Royal Bank of Canada858$2.00K0.00%−950−52.5%Reduced
SBI Securities Co., Ltd.547$1.72K0.00%−1−0.2%Reduced
Advisor Group Holdings, Inc.221$6930.00%−30−12.0%Reduced
Strengthening Families & Communities, LLC200$6280.00%00.0%Unchanged
Deutsche Bank AG0$00.00%−253,375−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−189,892−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−20,938−100.0%Sold out
Private Advisor Group, LLC0$00.00%−16,600−100.0%Sold out
State of Tennessee, Treasury Department0$00.00%−5,126−100.0%Sold out
Simplex Trading, LLC0$00.00%−3,258−100.0%Sold out