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Propel Bio Management, LLC

SEC CIK
0001969764
Latest filing
Aug 13, 2026

Holdings in Q4 2025

Holdings as of Dec 31, 2025, filed Feb 11, 2026. Long positions only; changes compare share counts with Q3 2025.

Institution overview
Positions
20
+4 vs. Q3 2025
Portfolio value
$117.1M
+$17.2M (+17.2%) vs. Q3 2025
Filed
Feb 11, 2026
SEC
Holdings of Propel Bio Management, LLC in Q4 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
PAGPPlains GP Holdings LPLTD PARTNR INT A1,272,360$24.4M20.8%00.0%UnchangedHistory
ACHVAchieve Life Sciences, Inc.COM3,786,425$18.8M16.1%00.0%UnchangedHistory
PHATPhathom Pharmaceuticals, Inc.COM740,918$12.3M10.5%+187,991+34.0%AddedHistory
VRDNViridian Therapeutics, Inc.COM282,531$8.79M7.5%+192,531+213.9%AddedHistory
MISTMilestone Pharmaceuticals Inc.COM4,118,321$8.32M7.1%−1,006,569−19.6%ReducedHistory
KYTXKyverna Therapeutics, Inc.COM666,666$6.27M5.4%+666,666NewHistory
CMPSCOMPASS Pathways plcSPONSORED ADS861,778$5.95M5.1%+351,778+69.0%AddedHistory
IVAInventiva S.A.ADS1,000,000$4.65M4.0%+1,000,000NewHistory
DCTHDelcath Systems, Inc.COM NEW438,509$4.43M3.8%00.0%UnchangedHistory
ABEOAbeona Therapeutics Inc.COM NEW830,780$4.38M3.7%−143,242−14.7%ReducedHistory
CLDXCelldex Therapeutics, Inc.COM NEW154,300$4.19M3.6%−700−0.5%ReducedHistory
NKTRNektar TherapeuticsCOM NEW82,822$3.50M3.0%+33,822+69.0%AddedHistory
OCSOculis Holding AGORDINARY SHARES172,839$3.45M2.9%+172,839NewHistory
SABSSAB Biotherapeutics, Inc.COM NEW652,881$2.44M2.1%+652,881NewHistory
RGNXREGENXBIO Inc.COM116,896$1.68M1.4%+116,896NewHistory
LONALeonaBio, Inc.COM149,279$1.13M1.0%00.0%UnchangedHistory
LENZLENZ Therapeutics, Inc.COM59,085$945.4K0.8%+59,085NewHistory
AARDAardvark Therapeutics, Inc.COM46,408$609.1K0.5%+46,408NewHistory
ZVRAZevra Therapeutics, Inc.COM NEW63,683$570.6K0.5%−168,191−72.5%ReducedHistory
KLRSKalaris Therapeutics, Inc.COM42,053$354.9K0.3%+42,053NewHistory

Sold out since Q3 2025 (4)

Positions held at the end of Q3 2025 that are gone from this filing.

Positions of Propel Bio Management, LLC sold out since Q3 2025
SecurityClassShares in Q3 2025Value in Q3 2025% of portfolio in Q3 2025History
AKROAkero Therapeutics, Inc.COM228,884$10.9M10.9%History
APLTApplied Therapeutics, Inc.COM11,285,420$6.83M6.8%History
TCRXTScan Therapeutics, Inc.COM1,932,304$3.52M3.5%History
JSPRJasper Therapeutics, Inc.COM NEW1,028,806$2.45M2.5%History