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TCG Crossover Management, LLC

SEC CIK
0001839948
Latest filing
Aug 14, 2026

Holdings in Q2 2026

Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.

Institution overview
Positions
54
+5 vs. Q1 2026
Portfolio value
$4.16B
+$665.1M (+19.0%) vs. Q1 2026
Filed
Aug 14, 2026
SEC
Holdings of TCG Crossover Management, LLC in Q2 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
ABVXAbivax S.A.SPONSORED ADS6,007,834$800.6M19.2%−473,251−7.3%ReducedHistory
TNGXTango Therapeutics, Inc.COM9,081,201$283.9M6.8%−1,449,870−13.8%ReducedHistory
CGONCG Oncology, Inc.COM3,670,206$260.8M6.3%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM4,854,436$187.9M4.5%−92,458−1.9%ReducedHistory
IMVTImmunovant, Inc.COM4,457,988$171.8M4.1%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW1,900,582$168.7M4.1%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM1,676,624$163.4M3.9%00.0%UnchangedHistory
MIRMMirum Pharmaceuticals, Inc.COM1,062,049$124.3M3.0%00.0%UnchangedHistory
ZLABZai Lab LtdADR6,137,627$116.6M2.8%+6,137,627NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM6,243,812$112.1M2.7%00.0%UnchangedHistory
GLUEMonte Rosa Therapeutics, Inc.COM4,622,151$111.9M2.7%00.0%UnchangedHistory
BCRXBiocryst Pharmaceuticals IncCOM11,020,968$110.2M2.6%00.0%UnchangedHistory
VORVor Biopharma Inc.COM NEW5,673,078$104.4M2.5%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM3,248,980$103.8M2.5%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM4,615,144$102.5M2.5%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM1,341,862$98.1M2.4%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM4,273,356$80.0M1.9%00.0%UnchangedHistory
SVRASavara IncCOM12,362,205$76.2M1.8%00.0%UnchangedHistory
AURAAura Biosciences, Inc.COM9,533,333$67.7M1.6%+9,533,333NewHistory
RVMDRevolution Medicines, Inc.COM340,899$63.8M1.5%−235,574−40.9%ReducedHistory
TRAXFirst Tracks Biotherapeutics, Inc.ORD SHS2,895,304$58.3M1.4%+2,895,304NewHistory
KODKodiak Sciences Inc.COM1,445,538$56.3M1.4%00.0%UnchangedHistory
AVTXAvalo Therapeutics, Inc.COM NEW3,017,120$55.8M1.3%+2,278,737+308.6%AddedHistory
LBRXLB Pharmaceuticals IncCOM SHS1,447,310$47.0M1.1%−392,179−21.3%ReducedHistory
IPSCCentury Therapeutics, Inc.COM17,754,430$43.4M1.0%00.0%UnchangedHistory
TECXTectonic Therapeutic, Inc.COM1,204,891$41.4M1.0%00.0%UnchangedHistory
XNCRXencor IncCOM2,452,138$39.5M0.9%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM NEW1,473,101$38.2M0.9%00.0%UnchangedHistory
EDITEditas Medicine, Inc.COM11,111,111$36.0M0.9%+11,111,111NewHistory
MBXMBX Biosciences, Inc.COM650,000$35.9M0.9%00.0%UnchangedHistory
PHVSPharvaris N.V.COM1,008,229$34.9M0.8%+1,008,229NewHistory
SLNSilence Therapeutics plcADS3,033,560$33.3M0.8%00.0%UnchangedHistory
IFRXInflaRx N.V.COM14,500,000$32.5M0.8%+14,500,000NewHistory
ALTAltimmune, Inc.COM NEW10,000,000$30.4M0.7%+10,000,000NewHistory
JANXJanux Therapeutics, Inc.COM1,789,617$27.5M0.7%00.0%UnchangedHistory
CATXPerspective Therapeutics, Inc.COM NEW7,915,567$27.0M0.6%00.0%UnchangedHistory
AGMBAgomAb Therapeutics NVSPONSORED ADS2,053,233$26.7M0.6%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM1,779,952$26.5M0.6%−2,851,365−61.6%ReducedHistory
AKTSAktis Oncology, Inc.COM696,560$22.5M0.5%+696,560NewHistory
ALECAlector, Inc.COM10,000,000$20.1M0.5%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM NEW920,000$19.6M0.5%+920,000NewHistory
MNPRMonopar TherapeuticsCOM NEW203,327$18.8M0.5%+71,224+53.9%AddedHistory
OCULOcular Therapeutix, IncCOM1,647,752$16.2M0.4%00.0%UnchangedHistory
ADCTADC Therapeutics SASHS11,390,175$12.2M0.3%00.0%UnchangedHistory
ALXOAlx Oncology Holdings IncCOM5,655,487$11.7M0.3%−7,356,362−56.5%ReducedHistory
TRDAEntrada Therapeutics, Inc.COM1,060,230$7.80M0.2%−1,227,270−53.7%ReducedHistory
CGEMCullinan Therapeutics, Inc.COM406,786$7.41M0.2%00.0%UnchangedHistory
ARVNArvinas, Inc.COM707,098$5.88M0.1%−1,680,363−70.4%ReducedHistory
KRROKorro Bio, Inc.COM416,301$5.49M0.1%00.0%UnchangedHistory
RACCResearch Alliance Corp IIIORD SHS CL A500,000$5.35M0.1%+500,000NewHistory
LONALeonaBio, Inc.COM464,398$4.27M0.1%00.0%UnchangedHistory
JATTJATT II Acquisition Corp.ORD SHS200,000$2.27M0.1%+200,000NewHistory
CNTXContext Therapeutics Inc.COM2,682,696$1.49M<0.1%00.0%UnchangedHistory
EIKNEikon Therapeutics, Inc.COM37,902$494.6K<0.1%+37,902NewHistory

Sold out since Q1 2026 (7)

Positions held at the end of Q1 2026 that are gone from this filing.

Positions of TCG Crossover Management, LLC sold out since Q1 2026
SecurityClassShares in Q1 2026Value in Q1 2026% of portfolio in Q1 2026History
CNTACentessa Pharmaceuticals plcSPONSORED ADS4,286,480$170.3M4.9%History
FULCFulcrum Therapeutics, Inc.COM5,250,000$40.3M1.2%History
LQDALiquidia CorpCOM NEW403,048$15.2M0.4%History
URGNUroGen Pharma Ltd.COM405,365$7.29M0.2%History
GPCRStructure Therapeutics Inc.SPONSORED ADS140,411$6.77M0.2%History
UPBUpstream Bio, Inc.COM181,063$1.63M<0.1%History
VTGNVistagen Therapeutics, Inc.COM2,676,580$1.53M<0.1%History