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TCG Crossover Management, LLC

SEC CIK
0001839948
Latest filing
Aug 14, 2026

Holdings in Q1 2024

Holdings as of Mar 31, 2024, filed May 15, 2024. Long positions only; changes compare share counts with Q4 2023.

Institution overview
Positions
33
+4 vs. Q4 2023
Portfolio value
$1.26B
+$363.2M (+40.3%) vs. Q4 2023
Filed
May 15, 2024
SEC
Holdings of TCG Crossover Management, LLC in Q1 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CGONCG Oncology, Inc.COM3,570,206$156.7M12.4%+3,570,206NewHistory
DYNDyne Therapeutics, Inc.COM2,650,150$75.2M5.9%+1,000,000+60.6%AddedHistory
ATXSAstria Therapeutics, Inc.COM5,278,928$74.3M5.9%+5,278,928NewHistory
SLNSilence Therapeutics plcADS3,295,350$71.2M5.6%+1,190,475+56.6%AddedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS1,598,421$68.5M5.4%−511,163−24.2%ReducedHistory
JBIOJade Biosciences, Inc.COM2,201,274$65.1M5.1%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM1,750,387$61.2M4.8%00.0%UnchangedHistory
KROSKeros Therapeutics, Inc.COM879,344$58.2M4.6%+879,344NewHistory
GERNGeron CorpCOM17,391,639$57.4M4.5%−5,984,200−25.6%ReducedHistory
SVRASavara IncCOM10,000,000$49.8M3.9%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM5,319,148$48.4M3.8%+5,319,148NewHistory
COGTCogent Biosciences, Inc.COM6,214,375$41.8M3.3%+583,333+10.4%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM2,272,728$41.5M3.3%+2,272,728NewHistory
MLYSMineralys Therapeutics, Inc.COM3,185,185$41.1M3.3%+3,185,185NewHistory
MDGLMadrigal Pharmaceuticals, Inc.COM149,283$39.9M3.2%−30,634−17.0%ReducedHistory
TRMLTourmaline Bio, Inc.COM1,477,593$33.8M2.7%+469,691+46.6%AddedHistory
TYRATyra Biosciences, Inc.COM1,989,103$32.6M2.6%00.0%UnchangedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS3,858,000$32.1M2.5%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,423,642$30.4M2.4%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM793,829$28.9M2.3%−349,028−30.5%ReducedHistory
ADVMAdverum Biotechnologies, Inc.COM2,008,340$28.4M2.2%+2,008,340NewHistory
SLNOSoleno Therapeutics IncCOM NEW550,000$23.5M1.9%+550,000NewHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS2,040,816$23.1M1.8%00.0%UnchangedHistory
ABVXAbivax S.A.SPONSORED ADS1,100,000$15.7M1.2%00.0%UnchangedHistory
VTGNVistagen Therapeutics, Inc.COM NEW2,676,580$14.1M1.1%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM1,163,356$13.8M1.1%−2,232,139−65.7%ReducedHistory
CCCCC4 Therapeutics, Inc.COM STK1,276,574$10.4M0.8%00.0%UnchangedHistory
TRDAEntrada Therapeutics, Inc.COM584,955$8.29M0.7%00.0%UnchangedHistory
ANTXAN2 Therapeutics, Inc.COM1,555,118$5.05M0.4%−1,123,091−41.9%ReducedHistory
KODKodiak Sciences Inc.COM899,999$4.73M0.4%+632,058+235.9%AddedHistory
VTYXVentyx Biosciences, Inc.COM815,724$4.49M0.4%00.0%UnchangedHistory
NKTRNektar TherapeuticsCOM4,000,000$3.74M0.3%+4,000,000NewHistory
CABACabaletta Bio, Inc.COM86,795$1.48M0.1%−400,000−82.2%ReducedHistory

Sold out since Q4 2023 (5)

Positions held at the end of Q4 2023 that are gone from this filing.

Positions of TCG Crossover Management, LLC sold out since Q4 2023
SecurityClassShares in Q4 2023Value in Q4 2023% of portfolio in Q4 2023History
ICVXIcosavax, Inc.COM3,703,704$58.4M6.5%History
RYZBRayzeBio, Inc.COM869,908$54.1M6.0%History
Gracell Biotechnologies Inc38406L103SPONSORED ADS4,514,786$45.3M5.0%–
NRIXNurix Therapeutics, Inc.COM717,654$7.41M0.8%History
TSHATaysha Gene Therapies, Inc.COM SHS2,912,861$5.16M0.6%History