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Darwin Global Management, Ltd.

SEC CIK
0001839209
Latest filing
Aug 14, 2026

Holdings in Q4 2021

Holdings as of Dec 31, 2021, filed Feb 14, 2022. Long positions only; changes compare share counts with Q3 2021.

Institution overview
Positions
13
+1 vs. Q3 2021
Portfolio value
$654.6M
+$111.3M (+20.5%) vs. Q3 2021
Filed
Feb 14, 2022
SEC
Holdings of Darwin Global Management, Ltd. in Q4 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
PFEPfizer IncStock7,697,762$454.6M69.4%+7,697,762NewHistory
NTLAIntellia Therapeutics, Inc.COM605,587$71.6M10.9%−146,437−19.5%ReducedHistory
AZNAstraZeneca PLCSPONSORED ADR511,908$29.8M4.6%+511,908NewHistory
INBXInhibrx Biosciences, Inc.COM591,975$25.9M3.9%+49,389+9.1%AddedHistory
BNTXBioNTech SESPONSORED ADS90,057$23.2M3.5%−42,875−32.3%ReducedHistory
ENTAEnanta Pharmaceuticals IncCOM166,190$12.4M1.9%+166,190NewHistory
FATEFate Therapeutics IncCOM153,537$8.98M1.4%−199,713−56.5%ReducedHistory
KROSKeros Therapeutics, Inc.COM111,500$6.52M1.0%+111,500NewHistory
VIRVir Biotechnology, Inc.COM145,841$6.11M0.9%+100,530+221.9%AddedHistory
ChemoCentryx, Inc.16383L106COM161,802$5.89M0.9%+161,802New–
FULCFulcrum Therapeutics, Inc.COM317,428$5.62M0.9%+283,431+833.7%AddedHistory
ACRSAclaris Therapeutics, Inc.COM216,143$3.14M0.5%+56,750+35.6%AddedHistory
VERVVerve Therapeutics, Inc.COM23,104$852.0K0.1%−4,293−15.7%ReducedHistory

Sold out since Q3 2021 (4)

Positions held at the end of Q3 2021 that are gone from this filing.

Positions of Darwin Global Management, Ltd. sold out since Q3 2021
SecurityClassShares in Q3 2021Value in Q3 2021% of portfolio in Q3 2021History
XLRNAcceleron Pharma IncCOM2,000,000$344.2M63.4%History
BBIOBridgeBio Pharma, Inc.COM253,692$11.9M2.2%History
IVVDInvivyd, Inc.COM86,528$3.65M0.7%History
JBIOJade Biosciences, Inc.COM12,484$262.0K<0.1%History