Avidity Partners Management LP
- SEC CIK
- 0001791827
- Latest filing
- Aug 14, 2026
Holdings in Q1 2022
Holdings as of Mar 31, 2022, filed May 16, 2022. Long positions only; changes compare share counts with Q4 2021.
- Positions
- 91
- −6 vs. Q4 2021
- Portfolio value
- $4.51B
- −$208.9M (−4.4%) vs. Q4 2021
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| AZNAstraZeneca PLC | SPONSORED ADR | 3,700,000 | $245.5M | 5.4% | +832,800+29.0% | Added | History |
| ABBVAbbVie Inc. | Stock | 1,466,100 | $237.7M | 5.3% | −518,900−26.1% | Reduced | History |
| ARVNArvinas, Inc. | COM | 2,915,300 | $196.2M | 4.4% | +387,327+15.3% | Added | History |
| ELVElevance Health, Inc. | Stock | 399,400 | $196.2M | 4.4% | +78,400+24.4% | Added | History |
| MRKMerck & Co., Inc. | Stock | 2,370,000 | $194.5M | 4.3% | +2,370,000 | New | History |
| AVTRAvantor, Inc. | COM | 5,668,300 | $191.7M | 4.3% | +876,300+18.3% | Added | History |
| BAXBaxter International Inc | Stock | 1,915,500 | $148.5M | 3.3% | +150,500+8.5% | Added | History |
| ZNTLZentalis Pharmaceuticals, Inc. | COM | 3,176,999 | $146.6M | 3.3% | +461,999+17.0% | Added | History |
| BHVNBiohaven Ltd. | COM | 1,231,000 | $146.0M | 3.2% | +91,000+8.0% | Added | History |
| VRTXVertex Pharmaceuticals Inc | Stock | 545,600 | $142.4M | 3.2% | +265,600+94.9% | Added | History |
| UNHUnitedHealth Group Inc | Stock | 259,600 | $132.4M | 2.9% | +136,500+110.9% | Added | History |
| UTHRUnited Therapeutics Corp | COM | 718,946 | $129.0M | 2.9% | +183,946+34.4% | Added | History |
| HZNPHorizon Therapeutics Public Ltd Co | SHS | 1,131,400 | $119.0M | 2.6% | +119,400+11.8% | Added | History |
| MRTXMirati Therapeutics, Inc. | COM | 1,393,000 | $114.5M | 2.5% | +586,600+72.7% | Added | History |
| ISEEIVERIC bio, Inc. | COM | 6,475,400 | $109.0M | 2.4% | −479,600−6.9% | Reduced | History |
| NBIXNeurocrine Biosciences Inc | Stock | 1,160,000 | $108.8M | 2.4% | −100,000−7.9% | Reduced | History |
| IOVAIovance Biotherapeutics, Inc. | COM | 6,043,219 | $100.6M | 2.2% | +2,263,219+59.9% | Added | History |
| ISRGIntuitive Surgical Inc | COM NEW | 325,000 | $98.0M | 2.2% | +325,000 | New | History |
| CTLTCatalent, Inc. | COM | 782,000 | $86.7M | 1.9% | +87,000+12.5% | Added | History |
| HUMHumana Inc | Stock | 198,900 | $86.6M | 1.9% | +198,900 | New | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 4,823,400 | $83.8M | 1.9% | 00.0% | Unchanged | History |
| BIIBBiogen Inc. | COM | 365,000 | $76.9M | 1.7% | +365,000 | New | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 869,000 | $63.1M | 1.4% | +169,000+24.1% | Added | History |
| JNJJohnson & Johnson | Stock | 354,000 | $62.7M | 1.4% | +354,000 | New | History |
| ACETAdicet Bio, Inc. | COM | 3,120,000 | $62.3M | 1.4% | +85,996+2.8% | Added | History |
| KZRKezar Life Sciences, Inc. | COM | 3,518,000 | $58.5M | 1.3% | +289,800+9.0% | Added | History |
| MCKMcKesson Corp | Stock | 189,500 | $58.0M | 1.3% | +189,500 | New | History |
| ARGXArgenx SE | SPONSORED ADR | 176,000 | $55.5M | 1.2% | +176,000 | New | History |
| BSXBoston Scientific Corp | Stock | 1,196,100 | $53.0M | 1.2% | +1,196,100 | New | History |
| NTRANatera, Inc. | COM | 1,300,000 | $52.9M | 1.2% | +360,000+38.3% | Added | History |
| EWEdwards Lifesciences Corp | Stock | 440,000 | $51.8M | 1.1% | +440,000 | New | History |
| ARWRArrowhead Pharmaceuticals, Inc. | COM | 955,000 | $43.9M | 1.0% | +80,000+9.1% | Added | History |
| IMCRImmunocore Holdings plc | ADS | 1,363,800 | $40.8M | 0.9% | +133,800+10.9% | Added | History |
| LEGNLegend Biotech Corp | SPONSORED ADS | 1,095,000 | $39.8M | 0.9% | +383,100+53.8% | Added | History |
| State Street SPDR S&P Biotech ETF78464A870 | ETF | 440,000 | $39.5M | 0.9% | +440,000 | New | – |
| BHCBausch Health Companies Inc. | Stock | 1,694,700 | $38.7M | 0.9% | +1,694,700 | New | History |
| Avidity Biosciences, Inc.05370A108 | COM | 2,045,000 | $37.8M | 0.8% | +230,000+12.7% | Added | – |
| INSMINSMED Inc | COM PAR $.01 | 1,354,539 | $31.8M | 0.7% | −95,461−6.6% | Reduced | History |
| ATECAlphatec Holdings, Inc. | COM NEW | 2,735,600 | $31.5M | 0.7% | −37,400−1.3% | Reduced | History |
| IDYAIDEAYA Biosciences, Inc. | COM | 2,690,000 | $30.1M | 0.7% | +137,000+5.4% | Added | History |
| ChemoCentryx, Inc.16383L106 | COM | 1,175,000 | $29.5M | 0.7% | +530,600+82.3% | Added | – |
| AXSMAxsome Therapeutics, Inc. | COM | 711,000 | $29.4M | 0.7% | −64,000−8.3% | Reduced | History |
| RCUSArcus Biosciences, Inc. | COM | 912,000 | $28.8M | 0.6% | +912,000 | New | History |
| NTLAIntellia Therapeutics, Inc. | COM | 390,075 | $28.3M | 0.6% | +390,075 | New | History |
| PHATPhathom Pharmaceuticals, Inc. | COM | 1,946,000 | $26.5M | 0.6% | +50,000+2.6% | Added | History |
| CRBUCaribou Biosciences, Inc. | COM | 2,819,067 | $25.9M | 0.6% | +145,000+5.4% | Added | History |
| NUVBNuvation Bio Inc. | COM CL A | 4,855,006 | $25.5M | 0.6% | −2,527,482−34.2% | Reduced | History |
| Bellus Health Inc New07987C204 | COM NEW | 3,685,000 | $25.4M | 0.6% | −90,000−2.4% | Reduced | – |
| SPNESeaSpine Holdings Corp | COM | 2,010,000 | $24.4M | 0.5% | 00.0% | Unchanged | History |
| PENPenumbra Inc | COM | 104,000 | $23.1M | 0.5% | +104,000 | New | History |
| SIBNSI-BONE, Inc. | COM | 1,000,000 | $22.6M | 0.5% | +12,600+1.3% | Added | History |
| VIRVir Biotechnology, Inc. | COM | 780,000 | $20.1M | 0.4% | +80,000+11.4% | Added | History |
| VRDNViridian Therapeutics, Inc. | COM | 1,040,000 | $19.2M | 0.4% | −238,261−18.6% | Reduced | History |
| BPMCBlueprint Medicines Corp | COM | 291,184 | $18.6M | 0.4% | −703,816−70.7% | Reduced | History |
| ALTAltimmune, Inc. | COM NEW | 2,865,000 | $17.4M | 0.4% | +100,000+3.6% | Added | History |
| EPIXESSA Pharma Inc. | COM NEW | 2,460,000 | $15.2M | 0.3% | 00.0% | Unchanged | History |
| SGENSeagen Inc. | COM | 100,000 | $14.4M | 0.3% | −585,000−85.4% | Reduced | History |
| LKFTLakefront Biotherapeutics NV | SPON ADR | 215,000 | $13.3M | 0.3% | +215,000 | New | History |
| IPSCCentury Therapeutics, Inc. | COM | 865,000 | $10.9M | 0.2% | +13,478+1.6% | Added | History |
| ALPNAlpine Immune Sciences, Inc. | COM | 1,207,000 | $10.8M | 0.2% | −138,000−10.3% | Reduced | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 210,000 | $10.7M | 0.2% | +210,000 | New | History |
| ANTXAN2 Therapeutics, Inc. | COM | 688,330 | $10.4M | 0.2% | +688,330 | New | History |
| ERASErasca, Inc. | COM | 995,000 | $8.56M | 0.2% | +995,000 | New | History |
| SSentinelOne, Inc. | CL A | 204,500 | $7.92M | 0.2% | −3,500−1.7% | Reduced | History |
| CYTCyteir Therapeutics, Inc. | COM | 1,850,000 | $6.97M | 0.2% | +4620.0% | Added | History |
| PHASPhaseBio Pharmaceuticals Inc | COM | 4,405,000 | $5.82M | 0.1% | 00.0% | Unchanged | History |
| CMAXCareMax, Inc. | COM CL A | 755,329 | $5.64M | 0.1% | −72,073−8.7% | Reduced | History |
| TNGXTango Therapeutics, Inc. | COM | 721,000 | $5.46M | 0.1% | +16,000+2.3% | Added | History |
| HYPRHyperfine, Inc. | COM CL A | 1,503,754 | $5.32M | 0.1% | −10,656−0.7% | Reduced | History |
| Medicus Sciences AcquisitionG5960S108 | CL A SHS | 520,000 | $5.09M | 0.1% | 00.0% | Unchanged | – |
| BCLS Acquisition CorpG0904B105 | COM CL A | 500,000 | $4.93M | 0.1% | 00.0% | Unchanged | – |
| Dynamics Special Purpose Cor268010105 | CLASS A COM | 500,000 | $4.93M | 0.1% | 00.0% | Unchanged | – |
| ARYDARYA Sciences Acquisition Corp IV | CL A | 500,000 | $4.90M | 0.1% | 00.0% | Unchanged | History |
| Panacea Acquisition Corp. IIG6882C106 | CL A SHS | 500,000 | $4.88M | 0.1% | 00.0% | Unchanged | – |
| MLTXMoonLake Immunotherapeutics | COM CL A | 400,000 | $4.44M | 0.1% | 00.0% | Unchanged | History |
| Field Trip Health Ord31656R102 | COM | 2,976,000 | $3.99M | 0.1% | −229,000−7.1% | Reduced | – |
| OBIOOrchestra BioMed Holdings, Inc. | ORD SHS | 400,000 | $3.96M | 0.1% | 00.0% | Unchanged | History |
| LENZLENZ Therapeutics, Inc. | COM | 710,000 | $3.62M | 0.1% | 00.0% | Unchanged | History |
| ONCSOncosec Medical Inc | COM | 2,945,000 | $3.39M | 0.1% | 00.0% | Unchanged | History |
| OTICOtonomy, Inc. | COM | 1,349,905 | $3.24M | 0.1% | +1,349,905 | New | History |
| WGSGeneDx Holdings Corp. | COMMON STOCK | 950,000 | $2.92M | 0.1% | 00.0% | Unchanged | History |
| CMPXCompass Therapeutics, Inc. | COM | 2,000,000 | $2.74M | 0.1% | 00.0% | Unchanged | History |
| GRTSGritstone bio, Inc. | COM | 560,000 | $2.31M | 0.1% | −3,810,000−87.2% | Reduced | History |
| SNCEScience 37 Holdings, Inc. | COM | 430,000 | $2.30M | 0.1% | +36,000+9.1% | Added | History |
| SCYXScynexis Inc | COM NEW | 544,043 | $2.13M | <0.1% | −1,695,235−75.7% | Reduced | History |
| PROKProkidney Corp. | CLASS A ORD SHS | 200,000 | $1.98M | <0.1% | 00.0% | Unchanged | History |
| AKLIAkili, Inc. | CLASS A ORD SHS | 200,000 | $1.98M | <0.1% | 00.0% | Unchanged | History |
| DNABSocial Capital Suvretta Holdings Corp. II | CLASS A ORD SHS | 200,000 | $1.95M | <0.1% | 00.0% | Unchanged | History |
| DNADSocial Capital Suvretta Holdings Corp. IV | CLASS A ORD SHS | 200,000 | $1.95M | <0.1% | 00.0% | Unchanged | History |
| Nuvation Bio Inc.67080N119 | *W EXP 07/07/202 | 99,999 | $76.0K | <0.1% | 00.0% | Unchanged | – |
| Medicus Sciences AcquisitionG5960S124 | *W EXP 02/12/202 | 57,770 | $25.0K | <0.1% | 00.0% | Unchanged | – |
Options (1)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| SPDR Ser Tr78464A900 | CALL | – | $296.6M |
Sold out since Q4 2021 (25)
Positions held at the end of Q4 2021 that are gone from this filing.
| Security | Class | Shares in Q4 2021 | Value in Q4 2021 | % of portfolio in Q4 2021 | History |
|---|---|---|---|---|---|
| PFEPfizer Inc | Stock | 2,090,000 | $123.4M | 2.6% | History |
| ARNAArena Pharmaceuticals Inc | COM NEW | 1,215,500 | $113.0M | 2.4% | History |
| LLYEli Lilly & Co | Stock | 344,800 | $95.2M | 2.0% | History |
| HOLXHologic Inc | COM | 1,064,000 | $81.5M | 1.7% | History |
| SHCSotera Health Co | COM | 2,960,000 | $69.7M | 1.5% | History |
| ALNYAlnylam Pharmaceuticals, Inc. | COM | 370,000 | $62.7M | 1.3% | History |
| STVNStevanato Group S.p.A. | ORD SHS | 2,541,893 | $57.1M | 1.2% | History |
| KYMRKymera Therapeutics, Inc. | COM | 670,000 | $42.5M | 0.9% | History |
| OCDXOrtho Clinical Diagnostics Holdings plc | ORD SHS | 1,790,000 | $38.3M | 0.8% | History |
| AMNAmn Healthcare Services Inc | COM | 280,100 | $34.3M | 0.7% | History |
| GBTGlobal Blood Therapeutics, Inc. | COM | 862,000 | $25.2M | 0.5% | History |
| RLMDRelmada Therapeutics, Inc. | COM | 731,536 | $16.5M | 0.3% | History |
| ACADAcadia Pharmaceuticals Inc | COM | 300,000 | $7.00M | 0.1% | History |
| TILInstil Bio, Inc. | COM | 408,140 | $6.98M | 0.1% | History |
| TRMLTourmaline Bio, Inc. | COM | 455,037 | $6.96M | 0.1% | History |
| DHDefinitive Healthcare Corp. | CLASS A COM | 250,000 | $6.83M | 0.1% | History |
| EQRXEQRx, Inc. | COM | 1,000,000 | $6.82M | 0.1% | History |
| GLUEMonte Rosa Therapeutics, Inc. | COM | 300,000 | $6.13M | 0.1% | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 485,000 | $5.78M | 0.1% | History |
| TRDAEntrada Therapeutics, Inc. | COM | 255,000 | $4.37M | 0.1% | History |
| SLGCSomaLogic, Inc. | CLASS A COM | 330,000 | $3.84M | 0.1% | History |
| MRUSMerus N.V. | COM | 103,000 | $3.27M | 0.1% | History |
| STTKShattuck Labs, Inc. | COM | 165,000 | $1.40M | <0.1% | History |
| TCRTAlaunos Therapeutics, Inc. | COM | 590,000 | $643.0K | <0.1% | History |
| SLGCWSomaLogic, Inc. | *W EXP 03/01/202 | 65,999 | $220.0K | <0.1% | History |