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Prosight Management, LP

SEC CIK
0001617201
Latest filing
Aug 14, 2026

Holdings in Q4 2021

Holdings as of Dec 31, 2021, filed Feb 14, 2022. Long positions only; changes compare share counts with Q3 2021.

Institution overview
Positions
32
−8 vs. Q3 2021
Portfolio value
$150.2M
−$20.7M (−12.1%) vs. Q3 2021
Filed
Feb 14, 2022
SEC
Holdings of Prosight Management, LP in Q4 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
PRTAProthena Corp Public Ltd CoSHS441,000$21.8M14.5%+117,700+36.4%AddedHistory
LKFTLakefront Biotherapeutics NVSPON ADR345,900$19.1M12.7%+95,220+38.0%AddedHistory
ALBOAlbireo Pharma, Inc.COM514,082$12.0M8.0%+69,062+15.5%AddedHistory
CUECue Biopharma, Inc.COM829,042$9.38M6.2%+173,857+26.5%AddedHistory
EHCEncompass Health CorpCOM122,187$7.97M5.3%+90,540+286.1%AddedHistory
OSCROscar Health, Inc.CL A925,000$7.26M4.8%+736,600+391.0%AddedHistory
CNVYConvey Health Solutions Holdings, Inc.COM777,000$6.50M4.3%+38,988+5.3%AddedHistory
KZRKezar Life Sciences, Inc.COM360,000$6.02M4.0%−269,957−42.9%ReducedHistory
ZGNXZogenix, Inc.COM NEW362,909$5.90M3.9%−127,973−26.1%ReducedHistory
CRLCharles River Laboratories International, Inc.COM15,481$5.83M3.9%+15,481NewHistory
KALVKalVista Pharmaceuticals, Inc.COM409,620$5.42M3.6%+152,229+59.1%AddedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM31,907$5.41M3.6%+31,907NewHistory
ALDXAldeyra Therapeutics, Inc.COM1,155,300$4.62M3.1%+420,300+57.2%AddedHistory
ARNAArena Pharmaceuticals IncCOM NEW45,000$4.18M2.8%−108,400−70.7%ReducedHistory
AGLagilon health, inc.COM150,000$4.05M2.7%+40,490+37.0%AddedHistory
MORFMorphic Holding, Inc.COM72,898$3.45M2.3%+2,898+4.1%AddedHistory
PRQRProQR Therapeutics N.V.SHS EURO356,617$2.86M1.9%+74,361+26.3%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM128,705$2.81M1.9%+128,705NewHistory
STTKShattuck Labs, Inc.COM260,243$2.21M1.5%+91,002+53.8%AddedHistory
CGTXCognition Therapeutics IncCOM301,979$1.91M1.3%+301,979NewHistory
Panacea Acquisition Corp. IIG6882C106CL A SHS195,855$1.90M1.3%+6,915+3.7%Added–
GMEDGlobus Medical IncStock20,188$1.46M1.0%+20,188NewHistory
ACCDAccolade, Inc.COM50,000$1.32M0.9%−47,988−49.0%ReducedHistory
CRSPCRISPR Therapeutics AGNAMEN AKT17,364$1.32M0.9%+17,364NewHistory
IOVAIovance Biotherapeutics, Inc.COM68,800$1.31M0.9%−205,961−75.0%ReducedHistory
SIOXSio Gene Therapies Inc.COMMON802,180$1.03M0.7%+308,972+62.6%AddedHistory
MRNAModerna, Inc.Stock3,700$940.0K0.6%+3,700NewHistory
CBAYCymaBay Therapeutics, Inc.COM166,775$564.0K0.4%+166,775NewHistory
PRCTPROCEPT BioRobotics CorpCOM20,000$500.0K0.3%+20,000NewHistory
XCURExicure, Inc.COM2,426,508$490.0K0.3%−2,698,492−52.7%ReducedHistory
ODTOdonate Therapeutics, Inc.COM298,900$404.0K0.3%+298,900NewHistory
SPRYARS Pharmaceuticals, Inc.COM53,815$358.0K0.2%+53,815NewHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Prosight Management, LP in Q4 2021
SecurityClassPutsCalls
Galapagos NV36315X901CALL–$11.0M
Prothena Corp PLCG72800908CALL–$2.57M
Progyny Inc74340E953PUT$2.52M–
West Pharmaceutical SVSC Inc955306955PUT$704.0K–

Sold out since Q3 2021 (19)

Positions held at the end of Q3 2021 that are gone from this filing.

Positions of Prosight Management, LP sold out since Q3 2021
SecurityClassShares in Q3 2021Value in Q3 2021% of portfolio in Q3 2021History
MTCRMetacrine, Inc.COM1,145,034$3.93M2.3%History
MGTXMeiraGTx Holdings plcCOM291,080$3.84M2.2%History
HUMHumana IncStock9,000$3.50M2.0%History
AMEDAmedisys IncCOM20,000$2.98M1.7%History
VRTXVertex Pharmaceuticals IncStock15,000$2.72M1.6%History
HAEHaemonetics CorpCOM38,319$2.71M1.6%History
ABBVAbbVie Inc.Stock24,800$2.67M1.6%History
IRTCiRhythm Holdings, Inc.COM37,396$2.19M1.3%History
ZBHZimmer Biomet Holdings, Inc.Stock13,000$1.90M1.1%History
WATWaters CorpCOM4,000$1.43M0.8%History
UNHUnitedHealth Group IncStock3,300$1.29M0.8%History
CLLSCellectis S.A.SPON ADS87,103$1.10M0.6%History
ASMBAssembly Biosciences, Inc.COM265,634$924.0K0.5%History
ALECAlector, Inc.COM27,378$625.0K0.4%History
LFSTLifeStance Health Group, Inc.COM38,774$562.0K0.3%History
ORGOOrganogenesis Holdings Inc.COM38,000$541.0K0.3%History
ONCROncorus, Inc.COM55,411$518.0K0.3%History
MDXGMimedx Group, Inc.COM44,225$268.0K0.2%History
APTOAptose Biosciences Inc.COM NEW70,563$154.0K0.1%History